-----------------------
| PDB : 4Q66
-----------------------
Chain : K
   1
strd MLSQTSIPEVKEDVIGYALHQRRARVGQFQDLGPPDLITLIKSLPSSSST
sunp MLSQTSIPEVKEDVIGYALHQRRARVGQFQDLGPPDLITLIKSLPSSSST
sres MLSQTSIPEVKEDVIGYALHQRRARVGQFQDLGPPDLITLIKSLPSSSST
spdb --SQTSIPEVKEDVIGYALHQRRARVGQFQDLGPPDLI------------
ssec --TTTTTCEECTTTTTHHHHHHHHTTTTTTTTTCCEET------------
srsa --qHPEEANDYPxfjcPEKgNASdOBplEjUADCAAAA------------
snac --------------------------------------------------

  51
strd TTATASANDNGATSNINGQDPTTIVTELHSHDKLKGQIGTFFYCMGIDTS
sunp TTATASANDNGATSNINGQDPTTIVTELHSHDKLKGQIGTFFYCMGIDTS
sres TTATASANDNGATSNINGQDPTTIVTELHSHDKLKGQIGTFFYCMGIDTS
spdb ----------------------------------------FFYCMGIDTS
ssec ----------------------------------------TTEEECCCTT
srsa ----------------------------------------EEAAABBCAL
snac --------------------------------------------------

 101
strd DPTSITIFAKKITDLFLDTPQIWFGKKKHFHVSKISISSWNAFRKYDVNI
sunp DPTSITIFAKKITDLFLDTPQIWFGKKKHFHVSKISISSWNAFRKYDVNI
sres DPTSITIFAKKITDLFLDTPQIWFGKKKHFHVSKISISSWNAFRKYDVNI
spdb DPTSITIFAKKITDLFLDTPQIWFGKK-HFHVSKISISSWNAFRKYDVNI
ssec THHHHHHHHHHHHHHHHTTTTTTTTTC-CCTTTTCCEEEEETTTTEEEEE
srsa WJfCBRUHGbfINPQOgigMkIUqklq-tmMfcPQFCADAABDcWGAABC
snac ----------------------------------------------

 151
strd IVHIPGTVQTYIINSDGEQSQLPSVAEASSGRNSQDLNVNMIWAETFMSG
sunp IVHIPGTVQTYIINSDGEQSQLPSVAEASSGRNSQDLNVNMIWAETFMSG
sres IVHIPGTVQTYIINSDGEQSQLPSVAEASSGRNSQDLNVNMIWAETFMSG
spdb IVH----VQTYIINSDGEQSQLPSV-----------LNVNMIWAETFMSG
ssec ETT----TEEEEETTTTCBCCCCCC-----------CHHHHHHHHHHHHH
srsa FNc----mdHEDAOXuMjdbfBZxx-----------xpJeQJDDAAAABB
snac 

 201
strd IVRDIMIMKDNRADGESQNLVETLIFNPFTSGELEDVANNFIKLFPLVYE
sunp IVRDIMIMKDNRADGESQNLVETLIFNPFTSGELEDVANNFIKLFPLVYE
sres IVRDIMIMKDNRADGESQNLVETLIFNPFTSGELEDVANNFIKLFPLVYE
spdb IVRDIMIMKDNRADGESQNLVETLIFNPFTSGELEDVANNFIKLFPLVYE
ssec HHHHHHHHHHCGGGTTTCCTTTEEECTTTTTTTTTCHHHHHHHHCGGGTT
srsa BAACAABAMKCRXZHCcKlAPBACAPBABRLWPxYQBAMGAAiIARcACf
snac 

 251
strd KGVYLDAPTHVLNPSLTNNYLVETLVEIVRLTKSLEACRKMLKKLIEIHP
sunp KGVYLDAPTHVLNPSLTNNYLVETLVEIVRLTKSLEACRKMLKKLIEIHP
sres KGVYLDAPTHVLNPSLTNNYLVETLVEIVRLTKSLEACRKMLKKLIEIHP
spdb KGVYLDAPTHVLNPSLTNNYLVETLVEIVRLTKSLEACRKMLKKLIEIHP
ssec TGGGGCCTTTTTTTTTTTTHHHHHHHHHHHHHCCHHHHHHHHHHHHHTTT
srsa JBRhAUABHPAMRNDMAGABAAEAAECAAPEAPAIZJAUkGAacDMjjJU
snac 

 301
strd EAVIILIRVYFACDLEIDAVDLINEQLNSPSSFLADDSKTSHIQLIFKSE
sunp EAVIILIRVYFACDLEIDAVDLINEQLNSPSSFLADDSKTSHIQLIFKSE
sres EAVIILIRVYFACDLEIDAVDLINEQLNSPSSFLADDSKTSHIQLIFKSE
spdb EAVIILIRVYFACDLE-DAVDLINEQLNSPSSFLAD---TSHIQLIFKSE
ssec THHHHHHHHHHHHCCC-HHHHHHHHHHCTTTTTTTT---CCHHHHHHHHH
srsa GABAAAAKAEMIEqKc-iAOnKAYVFMhNowFFKax---poeYMUOBVCD
snac 

 351
strd LLSIQSEFLLDVKRDYKLAKEVAMEAVNCAPNEFKTWYLLTRIYIKLNDM
sunp LLSIQSEFLLDVKRDYKLAKEVAMEAVNCAPNEFKTWYLLTRIYIKLNDM
sres LLSIQSEFLLDVKRDYKLAKEVAMEAVNCAPNEFKTWYLLTRIYIKLNDM
spdb LLSIQSEFLLDVKRDYKLAKEVAMEAVNCAPNEFKTWYLLTRIYIKLNDM
ssec HHHHHHHHHHHTTTCHHHHHHHHHHHHHHTTTTHHHHHHHHHHHHHHCCH
srsa AEDEMAOGHDdYfnMSldANbGAOZADkFBZbEALAJHACALAFCXLjPB
snac 

 401
strd SNALLSLNACPMSQVKEKYVLRRIAPITSDENLHLPLPLDASIEEISSLN
sunp SNALLSLNACPMSQVKEKYVLRRIAPITSDENLHLPLPLDASIEEISSLN
sres SNALLSLNACPMSQVKEKYVLRRIAPITSDENLHLPLPLDASIEEISSLN
spdb SNALLSLNACPMS-VKEKYVLRRIAPI---ENLHLPLPLD---------N
ssec HHHHHHHHHCCCC-CCCCCCCCTTTTC---CCEECCTTTT---------C
srsa TRAAJBABNBKJL-xKiIBKBZSAAhg---xTSHUGZDax---------i
snac 

 451
strd PMDVQLEQKSADPNLVNLSASSLKSTFQLAYKLLTEIVQITGWEQLLKYR
sunp PMDVQLEQKSADPNLVNLSASSLKSTFQLAYKLLTEIVQITGWEQLLKYR
sres PMDVQLEQKSADPNLVNLSASSLKSTFQLAYKLLTEIVQITGWEQLLKYR
spdb PMDVQLEQKSADPNLVNLSASSLKSTFQLAYKLLTEIVQITGWEQLLKYR
ssec CCCCCCCCCCCCHHHHHTTTTTTCHHHHHHHHHHHHHHHHHCHHHHHHHH
srsa PcPrqbXuTwQWebAYkCbBVmIUHAPLNABYBACOACbaESKlXATmPL
snac 

 501
strd SKIFVMEDEYQGSTSSIDEAEVRGNDISKMRSKRLCERWLDNLFMLLYED
sunp SKIFVMEDEYQGSTSSIDEAEVRGNDISKMRSKRLCERWLDNLFMLLYED
sres SKIFVMEDEYQGSTSSIDEAEVRGNDISKMRSKRLCERWLDNLFMLLYED
spdb SKIFVM------S---------------K-R---LCERWLDNLFMLLYED
ssec HHHBTT------T---------------T-B---CCTTHHHHHHHHHHHH
srsa jnGCWx------x---------------a-Y---kFalGAPaAAdBAZQA
snac 

 551
strd LKTYTDWQSEQLYFDAQNSKYHKLTVEWELFGLCAKRLGHLPEAAKAFQI
sunp LKTYTDWQSEQLYFDAQNSKYHKLTVEWELFGLCAKRLGHLPEAAKAFQI
sres LKTYTDWQSEQLYFDAQNSKYHKLTVEWELFGLCAKRLGHLPEAAKAFQI
spdb LKTYTDWQSEQLYFDA-----HKLTVEWELFGLCAKRLGHLPEAAKAFQI
ssec HHHHHHHHHHHHHHCC-----CCCHHHHHHHHHHHHHHCCHHHHHHHHHH
srsa KYDGdfDOdTMnnclx-----nIWDEJBGKAAMAATJAgKXWPBCbABcS
snac 

 601
strd GLSQRFSPVCAKNLLQFYIDEHKRIRRDSVSANSELTSSQILSSINDIDS
sunp GLSQRFSPVCAKNLLQFYIDEHKRIRRDSVSANSELTSSQILSSINDIDS
sres GLSQRFSPVCAKNLLQFYIDEHKRIRRDSVSANSELTSSQILSSINDIDS
spdb GLSQRFSPVCAKNLLQFYIDEHKRIRRDS------L-SS-I----NDIDS
ssec HHHHCCCHHHHHHHHHHHHHHHHHHHHHH------H-HH-H----HHHHH
srsa AJnbLGAIOAAHJBAYJJCUMCYZIfrlx------x-oX-H----YnDCL
snac 

 651
strd SIIDLVVKICCWNHRWYIEFSIILIDALSVAVQDMGITKVHNEIASRFSD
sunp SIIDLVVKICCWNHRWYIEFSIILIDALSVAVQDMGITKVHNEIASRFSD
sres SIIDLVVKICCWNHRWYIEFSIILIDALSVAVQDMGITKVHNEIASRFSD
spdb SIIDLVVKICCWNHRWYIEFSIILIDALSVAVQDMGITKVHNEIASRFSD
ssec HHHHHHHHHHHHHHHHCBCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCH
srsa KAAMCAARABHJDFKUADGADAGABQCAHHACnRDZNhaAOdMAQqjHYn
snac 

 701
strd PVAQLIDDNILNFLKNFTNDTFDN---------------
sunp PVAQLIDDNILNFLKNFTNDTFDN---------------
sres PVAQLIDDNILNFLKNFTNDTFDNGTENLYFQGHHHHHH
spdb PVAQLIDDNILNFLKNFTNDTF-----------------
ssec HHHHHHHHHHHHHHHHHTTTTC-----------------
srsa ZFAYFALaFBCQABecNATsXS-----------------
snac 

Chain : E
   1
strd MLSQTSIPEVKEDVIGYALHQRRARVGQFQDLGPPDLITLIKSLPSSSST
sunp MLSQTSIPEVKEDVIGYALHQRRARVGQFQDLGPPDLITLIKSLPSSSST
sres MLSQTSIPEVKEDVIGYALHQRRARVGQFQDLGPPDLITLIKSLPSSSST
spdb -LSQTSIPEVK--VIGYALHQRRARVG---DLGPPDLI------------
ssec -TTTTTTCBCC--TTTHHHHHHHHCCC---CCCCCEET------------
srsa -wiLOCHBdGx--xxgSGMiPGhmjHx---lAIRABCG------------
snac --------------------------------------------------

  51
strd TTATASANDNGATSNINGQDPTTIVTELHSHDKLKGQIGTFFYCMGIDTS
sunp TTATASANDNGATSNINGQDPTTIVTELHSHDKLKGQIGTFFYCMGIDTS
sres TTATASANDNGATSNINGQDPTTIVTELHSHDKLKGQIGTFFYCMGIDTS
spdb ----------------------------------------FFYCMGIDTS
ssec ----------------------------------------TTEEECCCTT
srsa ----------------------------------------JGDAABBIAM
snac --------------------------------------------------

 101
strd DPTSITIFAKKITDLFLDTPQIWFGKKKHFHVSKISISSWNAFRKYDVNI
sunp DPTSITIFAKKITDLFLDTPQIWFGKKKHFHVSKISISSWNAFRKYDVNI
sres DPTSITIFAKKITDLFLDTPQIWFGKKKHFHVSKISISSWNAFRKYDVNI
spdb DPTSITIFAKKITDLFLDTPQI----------S-IS-S-WNAFRKYDVNI
ssec THHHHHHHHHHHHHTTTCCCCC----------C-EE-E-EETTTTEEEEE
srsa WNfKBSbJGZhSZXPrgojblx----------b-DA-C-EAACbcGBBCB
snac --------------------------------------------------

 151
strd IVHIPGTVQTYIINSDGEQSQLPSVAEASSGRNSQDLNVNMIWAETFMSG
sunp IVHIPGTVQTYIINSDGEQSQLPSVAEASSGRNSQDLNVNMIWAETFMSG
sres IVHIPGTVQTYIINSDGEQSQLPSVAEASSGRNSQDLNVNMIWAETFMSG
spdb IV-----VQTYIINS-----------------N-----VNMIWAETFMSG
ssec ET-----TEEEEECC-----------------H-----HHHHHHHHHHHH
srsa Qj-----pldPXFls-----------------x-----fqQNHEAAAABC
snac --------------------------------

 201
strd IVRDIMIMKDNRADGESQNLVETLIFNPFTSGELEDVANNFIKLFPLVYE
sunp IVRDIMIMKDNRADGESQNLVETLIFNPFTSGELEDVANNFIKLFPLVYE
sres IVRDIMIMKDNRADGESQNLVETLIFNPFTSGELEDVANNFIKLFPLVYE
spdb IVRDIMIMKDNRADGESQNLVETLIFNPFTSG---DVANNFIKLFPLVYE
ssec HHHHHHHHHHCGGGTTTCCTTTEEECTTTTTT---THHHHHHHHCGGGTT
srsa BAACAAAALKBRYZHCVImIPIABAPBAARMx---eBBQOAAlHAQcBCg
snac 

 251
strd KGVYLDAPTHVLNPSLTNNYLVETLVEIVRLTKSLEACRKMLKKLIEIHP
sunp KGVYLDAPTHVLNPSLTNNYLVETLVEIVRLTKSLEACRKMLKKLIEIHP
sres KGVYLDAPTHVLNPSLTNNYLVETLVEIVRLTKSLEACRKMLKKLIEIHP
spdb KGVYLDAPTHVLNPSLTNNYLVETLVEIVRLTKSLEACRKMLKKLIEIHP
ssec TGGGGCCTTTTTTTTTTTTHHHHHHHHHHHHHCCHHHHHHHHHHHHHTTT
srsa JBThAWABHPBORODLAHABAAFAAEBAAPDAPALeKAVmEAYhDLoiIV
snac 

 301
strd EAVIILIRVYFACDLEIDAVDLINEQLNSPSSFLADDSKTSHIQLIFKSE
sunp EAVIILIRVYFACDLEIDAVDLINEQLNSPSSFLADDSKTSHIQLIFKSE
sres EAVIILIRVYFACDLEIDAVDLINEQLNSPSSFLADDSKTSHIQLIFKSE
spdb EAVIILIRVYFACDLEIDAVDLINEQLNSPSSFLAD---TSHIQLIFKSE
ssec THHHHHHHHHHHHCCHHHHHHHHHHHHCTTTTTTTT---CCHHHHHHHHH
srsa GABAAAAKABLHEpLTjYAPjKAZTFLhMnqFFKZx---pneXMVOBVDD
snac 

 351
strd LLSIQSEFLLDVKRDYKLAKEVAMEAVNCAPNEFKTWYLLTRIYIKLNDM
sunp LLSIQSEFLLDVKRDYKLAKEVAMEAVNCAPNEFKTWYLLTRIYIKLNDM
sres LLSIQSEFLLDVKRDYKLAKEVAMEAVNCAPNEFKTWYLLTRIYIKLNDM
spdb LLSIQSEFLLDVKRDYKLAKEVAMEAVNCAPNEFKTWYLLTRIYIKLNDM
ssec HHHHHHHHHHHTTTCHHHHHHHHHHHHHHTTTTHHHHHHHHHHHHHHCCH
srsa AECFMAPHHCcSdjSKndAMcGAOZADjFCacEAMAJHACAKAFCUQjPB
snac 

 401
strd SNALLSLNACPMSQVKEKYVLRRIAPITSDENLHLPLPLDASIEEISSLN
sunp SNALLSLNACPMSQVKEKYVLRRIAPITSDENLHLPLPLDASIEEISSLN
sres SNALLSLNACPMSQVKEKYVLRRIAPITSDENLHLPLPLDASIEEISSLN
spdb SNALLSLNACPMSQVKEKYVLR--API-----LHLPLP-----------N
ssec HHHHHHHHHCCCTTTTCCCCCC--CCC-----CBCCCC-----------C
srsa VRAAIBADTBLECuqKhJBKEi--Mlt-----nOcGkX-----------x
snac 

 451
strd PMDVQLEQKSADPNLVNLSASSLKSTFQLAYKLLTEIVQITGWEQLLKYR
sunp PMDVQLEQKSADPNLVNLSASSLKSTFQLAYKLLTEIVQITGWEQLLKYR
sres PMDVQLEQKSADPNLVNLSASSLKSTFQLAYKLLTEIVQITGWEQLLKYR
spdb PMDVQLEQKSADPNLVNLSASSLKSTFQLAYKLLTEIVQITGWEQLLKYR
ssec CCCCCCCCCCCCHHHHHTTTTTTCHHHHHHHHHHHHHHHHHCHHHHHHHH
srsa WNlopYaqUtRWfaAYkDbBVmIWJANLNABZBACOADbaESKlXASmRK
snac 

 501
strd SKIFVMEDEYQGSTSSIDEAEVRGNDISKMRSKRLCERWLDNLFMLLYED
sunp SKIFVMEDEYQGSTSSIDEAEVRGNDISKMRSKRLCERWLDNLFMLLYED
sres SKIFVMEDEYQGSTSSIDEAEVRGNDISKMRSKRLCERWLDNLFMLLYED
spdb SKIFV-------S---------------K-R---LCERWLDNLFMLLYED
ssec HHHTT-------T---------------T-T---CCTTHHHHHHHHHHHH
srsa mnGBm-------x---------------e-Z---lFblGANaAAcBAYPA
snac 

 551
strd LKTYTDWQSEQLYFDAQNSKYHKLTVEWELFGLCAKRLGHLPEAAKAFQI
sunp LKTYTDWQSEQLYFDAQNSKYHKLTVEWELFGLCAKRLGHLPEAAKAFQI
sres LKTYTDWQSEQLYFDAQNSKYHKLTVEWELFGLCAKRLGHLPEAAKAFQI
spdb LKTYTDWQSEQL-------K---LTVEWELFGLCAKRLGHLPEAAKAFQI
ssec HHHHHHHHHHHH-------C---CHHHHHHHHHHHHHHCCHHHHHHHHHH
srsa KYDEceDQhhbx-------X---UCDIEFJAAKAATJAeHXWOBCfABcR
snac 

 601
strd GLSQRFSPVCAKNLLQFYIDEHKRIRRDSVSANSELTSSQILSSINDIDS
sunp GLSQRFSPVCAKNLLQFYIDEHKRIRRDSVSANSELTSSQILSSINDIDS
sres GLSQRFSPVCAKNLLQFYIDEHKRIRRDSVSANSELTSSQILSSINDIDS
spdb GLSQRFSPVCAKNLLQFYIDEHKRIRRDS-------TSSQILSSINDIDS
ssec HHTTTCCHHHHHHHHHHHHHHHHHHHHHH-------CHHHHHHHHHHHHH
srsa AKoeMHCLOAAIJBAWJJCUMDgbIfnlv-------slfdSjaPFVmEAK
snac 

 651
strd SIIDLVVKICCWNHRWYIEFSIILIDALSVAVQDMGITKVHNEIASRFSD
sunp SIIDLVVKICCWNHRWYIEFSIILIDALSVAVQDMGITKVHNEIASRFSD
sres SIIDLVVKICCWNHRWYIEFSIILIDALSVAVQDMGITKVHNEIASRFSD
spdb SIIDLVVKICCWNHRWYIEFSIILIDALSVAVQDMGITKVHNEIASRFSD
ssec HHHHHHHHHHHHHHHHCBCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCH
srsa JAAMBAASABNGCGPRADGAFAHBAPBAIGACmREaPiaAOeNARqjLao
snac 

 701
strd PVAQLIDDNILNFLKNFTNDTFDN---------------
sunp PVAQLIDDNILNFLKNFTNDTFDN---------------
sres PVAQLIDDNILNFLKNFTNDTFDNGTENLYFQGHHHHHH
spdb PVAQLIDDNILNFLKNFTNDTF-----------------
ssec HHHHHHHHHHHHHHHHTTTTTC-----------------
srsa fLAXJAJUFBCQABeZNBSuXY-----------------
snac 

Chain : B
   1
strd MLSQTSIPEVKEDVIGYALHQRRARVGQFQDLGPPDLITLIKSLPSSSST
sunp MLSQTSIPEVKEDVIGYALHQRRARVGQFQDLGPPDLITLIKSLPSSSST
sres MLSQTSIPEVKEDVIGYALHQRRARVGQFQDLGPPDLITLIKSLPSSSST
spdb --SQTSIPEV----------QRRARVGQF-DLGP-DLI------------
ssec --CTTTTCBC----------CCCTTTTTT-TTTC-EET------------
srsa --xxQGOAea----------lbWmZRxxS-jAQM-DKT------------
snac --------------------------------------------------

  51
strd TTATASANDNGATSNINGQDPTTIVTELHSHDKLKGQIGTFFYCMGIDTS
sunp TTATASANDNGATSNINGQDPTTIVTELHSHDKLKGQIGTFFYCMGIDTS
sres TTATASANDNGATSNINGQDPTTIVTELHSHDKLKGQIGTFFYCMGIDTS
spdb ----------------------------------------FFYCMGIDTS
ssec ----------------------------------------TTEEECCCTT
srsa ----------------------------------------OHBAALEPCN
snac --------------------------------------------------

 101
strd DPTSITIFAKKITDLFLDTPQIWFGKKKHFHVSKISISSWNAFRKYDVNI
sunp DPTSITIFAKKITDLFLDTPQIWFGKKKHFHVSKISISSWNAFRKYDVNI
sres DPTSITIFAKKITDLFLDTPQIWFGKKKHFHVSKISISSWNAFRKYDVNI
spdb DPTSITIFA-----------------------S--S---WNAFRKYDV--
ssec THHHHHHHH-----------------------B--C---EETTTTEEC--
srsa WQgMNjnWw-----------------------f--C---DBBCffeZP--
snac --------------------------------------------------

 151
strd IVHIPGTVQTYIINSDGEQSQLPSVAEASSGRNSQDLNVNMIWAETFMSG
sunp IVHIPGTVQTYIINSDGEQSQLPSVAEASSGRNSQDLNVNMIWAETFMSG
sres IVHIPGTVQTYIINSDGEQSQLPSVAEASSGRNSQDLNVNMIWAETFMSG
spdb -V-----------N--------------------------MIWAETFMSG
ssec -H-----------H--------------------------HHHHHHHHHH
srsa -p-----------q--------------------------VVKEBAAAAC
snac --------------------------------------------------

 201
strd IVRDIMIMKDNRADGESQNLVETLIFNPFTSGELEDVANNFIKLFPLVYE
sunp IVRDIMIMKDNRADGESQNLVETLIFNPFTSGELEDVANNFIKLFPLVYE
sres IVRDIMIMKDNRADGESQNLVETLIFNPFTSGELEDVANNFIKLFPLVYE
spdb IVRDIMIMKDNRADGESQNLVETLIFNPFT---LEDVANNFIKLFPLVYE
ssec HHHHHHHHHHCGGGTTTCCTTTEEECTTTT---CCCHHHHHHHHCGGGTT
srsa BAACAAAANKDVZYGEdIuMTHBBASCBBa---xYMEAMJABlHARbACg
snac --------------------------------

 251
strd KGVYLDAPTHVLNPSLTNNYLVETLVEIVRLTKSLEACRKMLKKLIEIHP
sunp KGVYLDAPTHVLNPSLTNNYLVETLVEIVRLTKSLEACRKMLKKLIEIHP
sres KGVYLDAPTHVLNPSLTNNYLVETLVEIVRLTKSLEACRKMLKKLIEIHP
spdb KGVYLDAPTHV-NPSLTNNYLVETLVEIVRLTKSLEACRKMLKKLIEIHP
ssec TGGGGCCTTTT-CCTTTTTHHHHHHHHHHHHHCCHHHHHHHHHHHHHTTT
srsa IBThAVABHQG-UQEMAIABAAGAAECAAPEAQAKeLAWiFAXeBNqjJT
snac 

 301
strd EAVIILIRVYFACDLEIDAVDLINEQLNSPSSFLADDSKTSHIQLIFKSE
sunp EAVIILIRVYFACDLEIDAVDLINEQLNSPSSFLADDSKTSHIQLIFKSE
sres EAVIILIRVYFACDLEIDAVDLINEQLNSPSSFLADDSKTSHIQLIFKSE
spdb EAVIILIRVYFACDLEIDAVDLINEQLNSPSSFL---S---HIQLIFKSE
ssec THHHHHHHHHHHHCCHHHHHHHHHHHHCTTTTCC---C---CHHHHHHHH
srsa GABAAAAKACLIEpKSkYAPiKAYTENhMurMKU---u---mfPcOBWCC
snac 

 351
strd LLSIQSEFLLDVKRDYKLAKEVAMEAVNCAPNEFKTWYLLTRIYIKLNDM
sunp LLSIQSEFLLDVKRDYKLAKEVAMEAVNCAPNEFKTWYLLTRIYIKLNDM
sres LLSIQSEFLLDVKRDYKLAKEVAMEAVNCAPNEFKTWYLLTRIYIKLNDM
spdb LLSIQSEFLLDVKRDYKLAKEVAMEAVNCAPNEFKTWYLLTRIYIKLNDM
ssec HHHHHHHHHHHTTTCHHHHHHHHHHHHHHTTTTHHHHHHHHHHHHHHCCH
srsa AEDGLAOHHCWOdXWOmdANcGAPaAClPCafFDMAJHACAMAFCYPkPB
snac 

 401
strd SNALLSLNACPMSQVKEKYVLRRIAPITSDENLHLPLPLDASIEEISSLN
sunp SNALLSLNACPMSQVKEKYVLRRIAPITSDENLHLPLPLDASIEEISSLN
sres SNALLSLNACPMSQVKEKYVLRRIAPITSDENLHLPLPLDASIEEISSLN
spdb SNALLSLNACPMSQVKEKYVL--IAPI-----LHLPLPLD--------L-
ssec HHHHHHHHHCCCTTTTCCCCC--CCCC-----CBCCCCCC--------C-
srsa TQAAIBADUANIJnqMoKBbN--TFoj-----mbaGdGxY--------x-
snac 

 451
strd PMDVQLEQKSADPNLVNLSASSLKSTFQLAYKLLTEIVQITGWEQLLKYR
sunp PMDVQLEQKSADPNLVNLSASSLKSTFQLAYKLLTEIVQITGWEQLLKYR
sres PMDVQLEQKSADPNLVNLSASSLKSTFQLAYKLLTEIVQITGWEQLLKYR
spdb ------EQKS-DPNLVNLSASSLKSTFQLAYKLLTEIVQITGWEQLLKYR
ssec ------CCCC-CHHHHHTTTTTTCHHHHHHHHHHHHHHHHHCHHHHHHHH
srsa ------YxRw-XfaAelDcBUnJVKAKLNABYBACNAEbbFRLkXARlQL
snac 

 501
strd SKIFVMEDEYQGSTSSIDEAEVRGNDISKMRSKRLCERWLDNLFMLLYED
sunp SKIFVMEDEYQGSTSSIDEAEVRGNDISKMRSKRLCERWLDNLFMLLYED
sres SKIFVMEDEYQGSTSSIDEAEVRGNDISKMRSKRLCERWLDNLFMLLYED
spdb SKIFV-----------------------K-R---LCERWLDNLFMLLYED
ssec HHHTT-----------------------T-T---TCTTHHHHHHHHHHHH
srsa lkGCq-----------------------q-a---jFbkGANaAAcBAZOA
snac 

 551
strd LKTYTDWQSEQLYFDAQNSKYHKLTVEWELFGLCAKRLGHLPEAAKAFQI
sunp LKTYTDWQSEQLYFDAQNSKYHKLTVEWELFGLCAKRLGHLPEAAKAFQI
sres LKTYTDWQSEQLYFDAQNSKYHKLTVEWELFGLCAKRLGHLPEAAKAFQI
spdb LKTYTDWQSE---------K---LTVEWELFGLCAKRLGHLPEAAKAFQI
ssec HHHHHHHHHH---------C---CHHHHHHHHHHHHHHCCHHHHHHHHHH
srsa LYDFZgGaqr---------Y---UBGIHGKAALAAUJAcIWWOBCgABdT
snac 

 601
strd GLSQRFSPVCAKNLLQFYIDEHKRIRRDSVSANSELTSSQILSSINDIDS
sunp GLSQRFSPVCAKNLLQFYIDEHKRIRRDSVSANSELTSSQILSSINDIDS
sres GLSQRFSPVCAKNLLQFYIDEHKRIRRDSVSANSELTSSQILSSINDIDS
spdb GLSQRFSPVCAKNLLQFYIDEHKRIRRDSVS-----TSSQILSSINDIDS
ssec HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH-----CHHHHHHHHHHHHH
srsa AJneRTALPAAIJBATJJDVKCaaGZfeWox-----pomjQkaPEVmEBN
snac 

 651
strd SIIDLVVKICCWNHRWYIEFSIILIDALSVAVQDMGITKVHNEIASRFSD
sunp SIIDLVVKICCWNHRWYIEFSIILIDALSVAVQDMGITKVHNEIASRFSD
sres SIIDLVVKICCWNHRWYIEFSIILIDALSVAVQDMGITKVHNEIASRFSD
spdb SIIDLVVKICCWNHRWYIEF-IILIDALSVAVQDMG--KVHNEIASRFSD
ssec HHHHHHHHHHHHHHHHCBCC-HHHHHHHHHHHHHCC--HHHHHHHHHCCH
srsa JABMCAAUABTIEEUTADGD-AEDBLBANHAQrQDu--hBThNARplKZo
snac 

 701
strd PVAQLIDDNILNFLKNFTNDTFDN---------------
sunp PVAQLIDDNILNFLKNFTNDTFDN---------------
sres PVAQLIDDNILNFLKNFTNDTFDNGTENLYFQGHHHHHH
spdb PVAQLIDDNILNFLKNFTNDT------------------
ssec HHHHHHHHHHHHHHHHTTTCC------------------
srsa WHBZBAJYEBFPAHlZMDQxr------------------
snac 

Chain : H
   1
strd MLSQTSIPEVKEDVIGYALHQRRARVGQFQDLGPPDLITLIKSLPSSSST
sunp MLSQTSIPEVKEDVIGYALHQRRARVGQFQDLGPPDLITLIKSLPSSSST
sres MLSQTSIPEVKEDVIGYALHQRRARVGQFQDLGPPDLITLIKSLPSSSST
spdb ---------V----------------------------------------
ssec ---------H----------------------------------------
srsa ---------p----------------------------------------
snac --------------------------------------------------

  51
strd TTATASANDNGATSNINGQDPTTIVTELHSHDKLKGQIGTFFYCMGIDTS
sunp TTATASANDNGATSNINGQDPTTIVTELHSHDKLKGQIGTFFYCMGIDTS
sres TTATASANDNGATSNINGQDPTTIVTELHSHDKLKGQIGTFFYCMGIDTS
spdb -------N------------------------------------M-I---
ssec -------H------------------------------------H-H---
srsa -------q------------------------------------e-e---
snac --------------------------------------------------

 101
strd DPTSITIFAKKITDLFLDTPQIWFGKKKHFHVSKISISSWNAFRKYDVNI
sunp DPTSITIFAKKITDLFLDTPQIWFGKKKHFHVSKISISSWNAFRKYDVNI
sres DPTSITIFAKKITDLFLDTPQIWFGKKKHFHVSKISISSWNAFRKYDVNI
spdb ----------------------W------------------A--------
ssec ----------------------H------------------H--------
srsa ----------------------m------------------U--------
snac --------------------------------------------------

 151
strd IVHIPGTVQTYIINSDGEQSQLPSVAEASSGRNSQDLNVNMIWAETFMSG
sunp IVHIPGTVQTYIINSDGEQSQLPSVAEASSGRNSQDLNVNMIWAETFMSG
sres IVHIPGTVQTYIINSDGEQSQLPSVAEASSGRNSQDLNVNMIWAETFMSG
spdb -----------------E---------------------------T-MSG
ssec -----------------H---------------------------H-HHH
srsa -----------------Y---------------------------f-fOJ
snac --------------------------------------------------

 201
strd IVRDIMIMKDNRADGESQNLVETLIFNPFTSGELEDVANNFIKLFPLVYE
sunp IVRDIMIMKDNRADGESQNLVETLIFNPFTSGELEDVANNFIKLFPLVYE
sres IVRDIMIMKDNRADGESQNLVETLIFNPFTSGELEDVANNFIKLFPLVYE
spdb IVRDIMIMKDNRADGESQNL------NPFTSG----------K-------
ssec HHHHHHHTTTTGGGTTTCCC------TTTTTC----------C-------
srsa SDiZACUFMWRWZmGEafxx------TLQmpx----------n-------
snac --------------------------------------------------

 251
strd KGVYLDAPTHVLNPSLTNNYLVETLVEIVRLTKSLEACRKMLKKLIEIHP
sunp KGVYLDAPTHVLNPSLTNNYLVETLVEIVRLTKSLEACRKMLKKLIEIHP
sres KGVYLDAPTHVLNPSLTNNYLVETLVEIVRLTKSLEACRKMLKKLIEIHP
spdb -GVYLDAPTHVLNPSLTNNYLVETL-EIVRLTKSLEACRKMLK-LIE--P
ssec -CGGGCCTTTTTTTTTTTTHHHHHH-HHHHHHCCHHHHHHHHH-CCC--C
srsa -EUrRYBBQSCNRODYAHALQFFCS-GLBQIKPJMfYCarZAY-jNx--h
snac --------------------------------------------------

 301
strd EAVIILIRVYFACDLEIDAVDLINEQLNSPSSFLADDSKTSHIQLIFKSE
sunp EAVIILIRVYFACDLEIDAVDLINEQLNSPSSFLADDSKTSHIQLIFKSE
sres EAVIILIRVYFACDLEIDAVDLINEQLNSPSSFLADDSKTSHIQLIFKSE
spdb EAVIILIRVYFACDLEIDAVDLINEQL------------TSHIQLIFKSE
ssec CHHHHHHHHHHHHCCHHHHHHHHHHHH------------CCHHHHHHHHH
srsa TCCBEAAQCCLMEpMTjaAOhJAjmWa------------uqgThTKFWCD
snac --------------------------------------------------

 351
strd LLSIQSEFLLDVKRDYKLAKEVAMEAVNCAPNEFKTWYLLTRIYIKLNDM
sunp LLSIQSEFLLDVKRDYKLAKEVAMEAVNCAPNEFKTWYLLTRIYIKLNDM
sres LLSIQSEFLLDVKRDYKLAKEVAMEAVNCAPNEFKTWYLLTRIYIKLNDM
spdb LLSIQSEFLLDVKRDYKLAKEVAMEAVNCAPNEFKTWYLLTRIYIKLNDM
ssec HHHHHHHHHTTTTCCHHHHHHHHHHHHHHTTTTHHHHHHHHHHHHHHCCH
srsa DEDFMAQGHEcVhrXOlcANbHAOaACjFBabEANAJHACAMAFCZPnQB
snac --------------------------------------------------

 401
strd SNALLSLNACPMSQVKEKYVLRRIAPITSDENLHLPLPLDASIEEISSLN
sunp SNALLSLNACPMSQVKEKYVLRRIAPITSDENLHLPLPLDASIEEISSLN
sres SNALLSLNACPMSQVKEKYVLRRIAPITSDENLHLPLPLDASIEEISSLN
spdb SNALLSLNACPMSQVK------------S---------------------
ssec HHHHHHHHHCCCTTTT------------C---------------------
srsa VRAAJBACRBLGDovT------------d---------------------
snac -

 451
strd PMDVQLEQKSADPNLVNLSASSLKSTFQLAYKLLTEIVQITGWEQLLKYR
sunp PMDVQLEQKSADPNLVNLSASSLKSTFQLAYKLLTEIVQITGWEQLLKYR
sres PMDVQLEQKSADPNLVNLSASSLKSTFQLAYKLLTEIVQITGWEQLLKYR
spdb -------------------------TFQLAYKLLTEIVQITGWEQLLKYR
ssec -------------------------HHHHHHHHHHHHHHHHCHHHHHHHH
srsa -------------------------ANVMAEZBADNAEibFQKnVATnRL
snac 

 501
strd SKIFVMEDEYQGSTSSIDEAEVRGNDISKMRSKRLCERWLDNLFMLLYED
sunp SKIFVMEDEYQGSTSSIDEAEVRGNDISKMRSKRLCERWLDNLFMLLYED
sres SKIFVMEDEYQGSTSSIDEAEVRGNDISKMRSKRLCERWLDNLFMLLYED
spdb SKIFV-----------------------K-R---LCERWLDNLFMLLYED
ssec HTTTT-----------------------T-T---TCTTHHHHHHHHHHHH
srsa mmGBn-----------------------p-Z---jGckGAPaCAbTAaaE
snac 

 551
strd LKTYTDWQSEQLYFDAQNSKYHKLTVEWELFGLCAKRLGHLPEAAKAFQI
sunp LKTYTDWQSEQLYFDAQNSKYHKLTVEWELFGLCAKRLGHLPEAAKAFQI
sres LKTYTDWQSEQLYFDAQNSKYHKLTVEWELFGLCAKRLGHLPEAAKAFQI
spdb LKTYTDWQS----F-----------------GLCAKRLG--PEAAKA---
ssec HHHHHHHHH----H-----------------HHHHHHHC--HHHHHH---
srsa MZYNdlfdx----M-----------------QXCCZaDr--dSLLsd---
snac 

 601
strd GLSQRFSPVCAKNLLQFYIDEHKRIRRDSVSANSELTSSQILSSINDIDS
sunp GLSQRFSPVCAKNLLQFYIDEHKRIRRDSVSANSELTSSQILSSINDIDS
sres GLSQRFSPVCAKNLLQFYIDEHKRIRRDSVSANSELTSSQILSSINDIDS
spdb --S----PVCAKNLLQFYIDEHKRIR--S-S---------I----NDIDS
ssec --C----HHHHHHHHHHHHHHHHHHH--H-H---------H----HHHHH
srsa --v----OYbHJPPAVMNDcLEkmTr--x-X---------K----fmEKV
snac 

 651
strd SIIDLVVKICCWNHRWYIEFSIILIDALSVAVQDMGITKVHNEIASRFSD
sunp SIIDLVVKICCWNHRWYIEFSIILIDALSVAVQDMGITKVHNEIASRFSD
sres SIIDLVVKICCWNHRWYIEFSIILIDALSVAVQDMGITKVHNEIASRFSD
spdb SIIDLVVKICCWNH-----FSIILIDALSVAVQ--GITKVHNEIA-----
ssec HHHHHHHHHHHHHH-----CCHHHHHHHHHHHH--CHHHHHHHCC-----
srsa JAFaEAKfBGfeVs-----SDAFAKLCCTIIMx--khilCYmbOx-----
snac 

 701
strd PVAQLIDDNILNFLKNFTNDTFDN---------------
sunp PVAQLIDDNILNFLKNFTNDTFDN---------------
sres PVAQLIDDNILNFLKNFTNDTFDNGTENLYFQGHHHHHH
spdb PVAQLI---IL------TNDT------------------
ssec HHHHHH---TT------CCCC------------------
srsa xYNuUE---Sb------ocxt------------------
snac