STX10_HUMAN 2019

Gene Name STX10

Description Syntaxin-10

Length 249

9606

Sequence

>sp|O60499|STX10_HUMAN Syntaxin-10
MSLEDPFFVVRGEVQKAVNTARGLYQRWCELLQESAAVGREELDWTTNELRNGLRSIEWDLEDLEETIGIVEANPGKFKLPAGDLQERKVFVERMREAVQEMKDHMVSPTAVAFLERNNREILAGKPAAQKSPSDLLDASAVSATSRYIEEQQATQQLIMDEQDQQLEMVSGSIQVLKHMSGRVGEELDEQGIMLDAFAQEMDHTQSRMDGVLRKLAKVSHMTSDRRQWCAIAVLVGVLLLVLILLFSL

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

STX6_HUMAN

Syntaxin-6

0.331

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

STX6_HUMAN

Syntaxin-6

0.256

NDUV2_HUMAN

NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

0.362

NDUV1_HUMAN

NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

0.363

NDUS8_HUMAN

NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial

0.367

NDUA9_HUMAN

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial

0.372

NDUF5_HUMAN

Arginine-hydroxylase NDUFAF5, mitochondrial

0.372

NDUS7_HUMAN

NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

0.372

EIF3F_HUMAN

Eukaryotic translation initiation factor 3 subunit F

0.374

SND1_HUMAN

Staphylococcal nuclease domain-containing protein 1

0.374

RBM42_HUMAN

RNA-binding protein 42

0.375

CAND1_HUMAN

Cullin-associated NEDD8-dissociated protein 1

0.375

CSN2_HUMAN

COP9 signalosome complex subunit 2

0.378

PA2G4_HUMAN

Proliferation-associated protein 2G4

0.379

PPT1_HUMAN

Palmitoyl-protein thioesterase 1

0.380

AP2A1_HUMAN

AP-2 complex subunit alpha-1

0.384

MPU1_HUMAN

Mannose-P-dolichol utilization defect 1 protein

0.386

IMDH1_HUMAN

Inosine-5-monophosphate dehydrogenase 1

0.386

VPS54_HUMAN

Vacuolar protein sorting-associated protein 54

0.388

EIF3H_HUMAN

Eukaryotic translation initiation factor 3 subunit H

0.389

GANAB_HUMAN

Neutral alpha-glucosidase AB

0.389

AAKG1_HUMAN

5-AMP-activated protein kinase subunit gamma-1

0.389

CERS5_HUMAN

Ceramide synthase 5

0.390

GRWD1_HUMAN

Glutamate-rich WD repeat-containing protein 1

0.390

NDUF7_HUMAN

Protein arginine methyltransferase NDUFAF7, mitochondrial

0.390

GUAA_HUMAN

GMP synthase [glutamine-hydrolyzing]

0.391

VPS36_HUMAN

Vacuolar protein-sorting-associated protein 36

0.391

H2A1_HUMAN

Histone H2A type 1

0.391

PRP19_HUMAN

Pre-mRNA-processing factor 19

0.391

EFTU_HUMAN

Elongation factor Tu, mitochondrial

0.392

UMPS_HUMAN

Uridine 5-monophosphate synthase

0.392

CISY_HUMAN

Citrate synthase, mitochondrial

0.392

F261_HUMAN

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1

0.392

H2A2B_HUMAN

Histone H2A type 2-B

0.392

AP2M1_HUMAN

AP-2 complex subunit mu

0.393

H2A1B_HUMAN

Histone H2A type 1-B/E

0.393

KCC1D_HUMAN

Calcium/calmodulin-dependent protein kinase type 1D

0.393

LETM1_HUMAN

Mitochondrial proton/calcium exchanger protein

0.393

ANM1_HUMAN

Protein arginine N-methyltransferase 1

0.394

H2A1C_HUMAN

Histone H2A type 1-C

0.394

MPCP_HUMAN

Phosphate carrier protein, mitochondrial

0.394

PGP_HUMAN

Glycerol-3-phosphate phosphatase

0.394

EXOS4_HUMAN

Exosome complex component RRP41

0.394

SPEE_HUMAN

Spermidine synthase

0.394

H2B3B_HUMAN

Histone H2B type 3-B

0.394

U5S1_HUMAN

116 kDa U5 small nuclear ribonucleoprotein component

0.395

IMPA1_HUMAN

Inositol monophosphatase 1

0.395

SRP68_HUMAN

Signal recognition particle subunit SRP68

0.395

PPWD1_HUMAN

Peptidylprolyl isomerase domain and WD repeat-containing protein 1

0.395

ATP7B_HUMAN

Copper-transporting ATPase 2

0.395

STX16_HUMAN

Syntaxin-16

0.396

NDUS4_HUMAN

NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial

0.396

H2A1A_HUMAN

Histone H2A type 1-A

0.396

AAKG3_HUMAN

5-AMP-activated protein kinase subunit gamma-3

0.396

AT2B3_HUMAN

Plasma membrane calcium-transporting ATPase 3

0.396

FPPS_HUMAN

Farnesyl pyrophosphate synthase

0.396

AP1B1_HUMAN

AP-1 complex subunit beta-1

0.396

KCC1A_HUMAN

Calcium/calmodulin-dependent protein kinase type 1

0.396

CAB39_HUMAN

Calcium-binding protein 39

0.396

G6PD_HUMAN

Glucose-6-phosphate 1-dehydrogenase

0.397

SMAP1_HUMAN

Stromal membrane-associated protein 1

0.397

HEMH_HUMAN

Ferrochelatase, mitochondrial

0.397

VPS52_HUMAN

Vacuolar protein sorting-associated protein 52 homolog

0.397

SF3B3_HUMAN

Splicing factor 3B subunit 3

0.397

MPI_HUMAN

Mannose-6-phosphate isomerase

0.397

PNKP_HUMAN

Bifunctional polynucleotide phosphatase/kinase

0.397

PRP31_HUMAN

U4/U6 small nuclear ribonucleoprotein Prp31

0.397

SCYL1_HUMAN

N-terminal kinase-like protein

0.397

EIF3E_HUMAN

Eukaryotic translation initiation factor 3 subunit E

0.398

BCS1_HUMAN

Mitochondrial chaperone BCS1

0.398

MPPB_HUMAN

Mitochondrial-processing peptidase subunit beta

0.398

CB39L_HUMAN

Calcium-binding protein 39-like

0.398

LIAS_HUMAN

Lipoyl synthase, mitochondrial

0.398

ATPG_HUMAN

ATP synthase subunit gamma, mitochondrial

0.398

SDHB_HUMAN

Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

0.398

GCH1_HUMAN

GTP cyclohydrolase 1

0.399

DX39B_HUMAN

Spliceosome RNA helicase DDX39B

0.399

H2AJ_HUMAN

Histone H2A.J

0.399

CPSF1_HUMAN

Cleavage and polyadenylation specificity factor subunit 1

0.399

SGPL1_HUMAN

Sphingosine-1-phosphate lyase 1

0.399

CAP2_HUMAN

Adenylyl cyclase-associated protein 2

0.399

EIF3D_HUMAN

Eukaryotic translation initiation factor 3 subunit D

0.399

NCPR_HUMAN

NADPH--cytochrome P450 reductase

0.399

ULA1_HUMAN

NEDD8-activating enzyme E1 regulatory subunit

0.399

H2A2A_HUMAN

Histone H2A type 2-A

0.399

SNR40_HUMAN

U5 small nuclear ribonucleoprotein 40 kDa protein

0.399

CPSF2_HUMAN

Cleavage and polyadenylation specificity factor subunit 2

0.399

CHMP5_HUMAN

Charged multivesicular body protein 5

0.399

PURA1_HUMAN

Adenylosuccinate synthetase isozyme 1

0.399

SYF1_HUMAN

Pre-mRNA-splicing factor SYF1

0.399

EFGM_HUMAN

Elongation factor G, mitochondrial

0.399

DLDH_HUMAN

Dihydrolipoyl dehydrogenase, mitochondrial

0.399

XPO2_HUMAN

Exportin-2

0.399

CBS_HUMAN

Cystathionine beta-synthase

0.399

CBSL_HUMAN

Cystathionine beta-synthase-like protein

0.399

GLYM_HUMAN

Serine hydroxymethyltransferase, mitochondrial

0.399

KAT3_HUMAN

Kynurenine--oxoglutarate transaminase 3

0.399

TBCB_HUMAN

Tubulin-folding cofactor B

0.399

DCOR_HUMAN

Ornithine decarboxylase

0.400

PURA2_HUMAN

Adenylosuccinate synthetase isozyme 2

0.400

ABCB5_HUMAN

ATP-binding cassette sub-family B member 5

0.400

CRNL1_HUMAN

Crooked neck-like protein 1

0.400

MDHM_HUMAN

Malate dehydrogenase, mitochondrial

0.400

SMYD3_HUMAN

Histone-lysine N-methyltransferase SMYD3

0.400

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 120 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy