OXDA_HUMAN 2019

Gene Name OXDA

Description D-amino-acid oxidase

Length 347

9606

Sequence

>sp|P14920|OXDA_HUMAN D-amino-acid oxidase
MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAGLWQPYLSDPNNPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLTPRELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGADVIVNCTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHDPERGIYNSPYIIPGTQTVTLGGIFQLGNWSELNNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGPSNTEVIHNYGHGGYGLTIHWGCALEAAKLFGRILEEKKLSRMPPSHL

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

OXDD_HUMAN

D-aspartate oxidase

0.336

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

OXDD_HUMAN

D-aspartate oxidase

0.216

ACON_HUMAN

Aconitate hydratase, mitochondrial

0.338

ACATN_HUMAN

Acetyl-coenzyme A transporter 1

0.353

S2536_HUMAN

Solute carrier family 25 member 36

0.362

TSC2_HUMAN

Tuberin

0.364

CACP_HUMAN

Carnitine O-acetyltransferase

0.365

AADAT_HUMAN

Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial

0.366

AL4A1_HUMAN

Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial

0.369

DOT1L_HUMAN

Histone-lysine N-methyltransferase, H3 lysine-79 specific

0.370

CMC1_HUMAN

Calcium-binding mitochondrial carrier protein Aralar1

0.370

FBXW7_HUMAN

F-box/WD repeat-containing protein 7

0.371

S35F6_HUMAN

Solute carrier family 35 member F6

0.372

SOS1_HUMAN

Son of sevenless homolog 1

0.372

CCHL_HUMAN

Cytochrome c-type heme lyase

0.377

VIGLN_HUMAN

Vigilin

0.378

S2533_HUMAN

Solute carrier family 25 member 33

0.379

PAN3_HUMAN

PAN2-PAN3 deadenylation complex subunit PAN3

0.380

ASM_HUMAN

Sphingomyelin phosphodiesterase

0.380

CNDP2_HUMAN

Cytosolic non-specific dipeptidase

0.381

PLPL6_HUMAN

Neuropathy target esterase

0.381

CLAT_HUMAN

Choline O-acetyltransferase

0.382

DEPD5_HUMAN

GATOR complex protein DEPDC5

0.383

PYC_HUMAN

Pyruvate carboxylase, mitochondrial

0.383

NPRL2_HUMAN

GATOR complex protein NPRL2

0.385

SOS2_HUMAN

Son of sevenless homolog 2

0.386

RRAGA_HUMAN

Ras-related GTP-binding protein A

0.386

RCC1_HUMAN

Regulator of chromosome condensation

0.386

TBC20_HUMAN

TBC1 domain family member 20

0.386

AT133_HUMAN

Probable cation-transporting ATPase 13A3

0.387

PAK2_HUMAN

Serine/threonine-protein kinase PAK 2

0.387

PLPL7_HUMAN

Patatin-like phospholipase domain-containing protein 7

0.387

SYCC_HUMAN

Cysteine--tRNA ligase, cytoplasmic

0.388

RICTR_HUMAN

Rapamycin-insensitive companion of mTOR

0.388

RMND1_HUMAN

Required for meiotic nuclear division protein 1 homolog

0.389

TRM44_HUMAN

Probable tRNA (uracil-O(2)-)-methyltransferase

0.389

C560_HUMAN

Succinate dehydrogenase cytochrome b560 subunit, mitochondrial

0.389

PAN2_HUMAN

PAN2-PAN3 deadenylation complex catalytic subunit PAN2

0.390

HID1_HUMAN

Protein HID1

0.390

S39A9_HUMAN

Zinc transporter ZIP9

0.390

DPP4_HUMAN

Dipeptidyl peptidase 4

0.390

SLMAP_HUMAN

Sarcolemmal membrane-associated protein

0.390

LIS1_HUMAN

Platelet-activating factor acetylhydrolase IB subunit alpha

0.390

DYHC1_HUMAN

Cytoplasmic dynein 1 heavy chain 1

0.391

TOM70_HUMAN

Mitochondrial import receptor subunit TOM70

0.391

STRP1_HUMAN

Striatin-interacting protein 1

0.392

CLCN3_HUMAN

H(+)/Cl(-) exchange transporter 3

0.392

SEPT7_HUMAN

Septin-7

0.393

LMA2L_HUMAN

VIP36-like protein

0.393

DPOG1_HUMAN

DNA polymerase subunit gamma-1

0.394

GOLP3_HUMAN

Golgi phosphoprotein 3

0.395

DCPS_HUMAN

m7GpppX diphosphatase

0.395

DC1I2_HUMAN

Cytoplasmic dynein 1 intermediate chain 2

0.396

CLCN4_HUMAN

H(+)/Cl(-) exchange transporter 4

0.396

SURF4_HUMAN

Surfeit locus protein 4

0.396

PAK1_HUMAN

Serine/threonine-protein kinase PAK 1

0.396

HIP1_HUMAN

Huntingtin-interacting protein 1

0.396

PAK3_HUMAN

Serine/threonine-protein kinase PAK 3

0.396

GSH1_HUMAN

Glutamate--cysteine ligase catalytic subunit

0.397

PGPS1_HUMAN

CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial

0.397

DPP10_HUMAN

Inactive dipeptidyl peptidase 10

0.398

GGPPS_HUMAN

Geranylgeranyl pyrophosphate synthase

0.398

ZNT1_HUMAN

Zinc transporter 1

0.399

PAXI_HUMAN

Paxillin

0.399

RRAGC_HUMAN

Ras-related GTP-binding protein C

0.399

AT2C1_HUMAN

Calcium-transporting ATPase type 2C member 1

0.400

TXTP_HUMAN

Tricarboxylate transport protein, mitochondrial

0.400

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 91 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy