QSPP_HUMAN 2019

Gene Name QSPP

Description Queuosine salvage protein

Length 341

9606

Sequence

>sp|Q5T6V5|QSPP_HUMAN Queuosine salvage protein
MDGLLNPRESSKFIAENSRDVFIDSGGVRRVAELLLAKAAGPELRVEGWKALHELNPRAADEAAVNWVFVTDTLNFSFWSEQDEHKCVVRYRGKTYSGYWSLCAAVNRALDEGIPITSASYYATVTLDQVRNILRSDTDVSMPLVEERHRILNETGKILLEKFGGSFLNCVRESENSAQKLMHLVVESFPSYRDVTLFEGKRVSFYKRAQILVADTWSVLEGKGDGCFKDISSITMFADYRLPQVLAHLGALKYSDDLLKKLLKGEMLSYGDRQEVEIRGCSLWCVELIRDCLLELIEQKGEKPNGEINSILLDYYLWDYAHDHREDMKGIPFHRIRCIYY

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

No protein with similar profile across the domains were found

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

TGT_HUMAN

Queuine tRNA-ribosyltransferase catalytic subunit 1

0.338

S35F1_HUMAN

Solute carrier family 35 member F1

0.357

S35F2_HUMAN

Solute carrier family 35 member F2

0.362

CSN1_HUMAN

COP9 signalosome complex subunit 1

0.362

RPN2_HUMAN

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

0.367

SUOX_HUMAN

Sulfite oxidase, mitochondrial

0.368

GEPH_HUMAN

Gephyrin

0.369

HGD_HUMAN

Homogentisate 1,2-dioxygenase

0.371

DDB1_HUMAN

DNA damage-binding protein 1

0.372

VPS51_HUMAN

Vacuolar protein sorting-associated protein 51 homolog

0.373

PPIL2_HUMAN

RING-type E3 ubiquitin-protein ligase PPIL2

0.375

UCHL5_HUMAN

Ubiquitin carboxyl-terminal hydrolase isozyme L5

0.379

PIMT_HUMAN

Protein-L-isoaspartate(D-aspartate) O-methyltransferase

0.379

CSN4_HUMAN

COP9 signalosome complex subunit 4

0.381

ODB2_HUMAN

Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

0.381

ACLY_HUMAN

ATP-citrate synthase

0.382

EIF3M_HUMAN

Eukaryotic translation initiation factor 3 subunit M

0.385

TASP1_HUMAN

Threonine aspartase 1

0.385

MOCS1_HUMAN

Molybdenum cofactor biosynthesis protein 1

0.386

MOCOS_HUMAN

Molybdenum cofactor sulfurase

0.388

ARL8B_HUMAN

ADP-ribosylation factor-like protein 8B

0.390

PIN4_HUMAN

Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4

0.391

RBM39_HUMAN

RNA-binding protein 39

0.391

CAND1_HUMAN

Cullin-associated NEDD8-dissociated protein 1

0.391

MCCB_HUMAN

Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

0.391

YIPF1_HUMAN

Protein YIPF1

0.391

STALP_HUMAN

AMSH-like protease

0.392

KDM8_HUMAN

Bifunctional peptidase and arginyl-hydroxylase JMJD5

0.393

OGT1_HUMAN

UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

0.394

ACSF2_HUMAN

Acyl-CoA synthetase family member 2, mitochondrial

0.394

CLPP_HUMAN

ATP-dependent Clp protease proteolytic subunit, mitochondrial

0.394

EIF3L_HUMAN

Eukaryotic translation initiation factor 3 subunit L

0.394

CP4V2_HUMAN

Cytochrome P450 4V2

0.395

STABP_HUMAN

STAM-binding protein

0.395

PPWD1_HUMAN

Peptidylprolyl isomerase domain and WD repeat-containing protein 1

0.395

HEXB_HUMAN

Beta-hexosaminidase subunit beta

0.395

CLPT1_HUMAN

Cleft lip and palate transmembrane protein 1

0.395

VPS36_HUMAN

Vacuolar protein-sorting-associated protein 36

0.396

TIM_HUMAN

Protein timeless homolog

0.397

IVD_HUMAN

Isovaleryl-CoA dehydrogenase, mitochondrial

0.398

ODBB_HUMAN

2-oxoisovalerate dehydrogenase subunit beta, mitochondrial

0.398

CTBL1_HUMAN

Beta-catenin-like protein 1

0.399

EIF3D_HUMAN

Eukaryotic translation initiation factor 3 subunit D

0.399

ODBA_HUMAN

2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial

0.399

GPTC1_HUMAN

G patch domain-containing protein 1

0.400

CD11B_HUMAN

Cyclin-dependent kinase 11B

0.400

CHRD1_HUMAN

Cysteine and histidine-rich domain-containing protein 1

0.400

EIF3E_HUMAN

Eukaryotic translation initiation factor 3 subunit E

0.400

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 119 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy