IN80C_HUMAN 2019

Gene Name IN80C

Description INO80 complex subunit C

Length 192

9606

Sequence

>sp|Q6PI98|IN80C_HUMAN INO80 complex subunit C
MAAQIPIVATTSTPGIVRNSKKRPASPSHNGSSGGGYGASKKKKASASSFAQGISMEAMSENKMVPSEFSTGPVEKAAKPLPFKDPNFVHSGHGGAVAGKKNRTWKNLKQILASERALPWQLNDPNYFSIDAPPSFKPAKKYSDVSGLLANYTDPQSKLRFSTIEEFSYIRRLPSDVVTGYLALRKATSIVP

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

No protein with similar profile across the domains were found

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

ARP5_HUMAN

Actin-related protein 5

0.295

ARP8_HUMAN

Actin-related protein 8

0.297

INO80_HUMAN

Chromatin-remodeling ATPase INO80

0.303

GID4_HUMAN

Glucose-induced degradation protein 4 homolog

0.365

THG1_HUMAN

Probable tRNA(His) guanylyltransferase

0.366

SYMC_HUMAN

Methionine--tRNA ligase, cytoplasmic

0.370

IPO11_HUMAN

Importin-11

0.371

MIA40_HUMAN

Mitochondrial intermembrane space import and assembly protein 40

0.373

OSBL8_HUMAN

Oxysterol-binding protein-related protein 8

0.374

PPOX_HUMAN

Protoporphyrinogen oxidase

0.376

HEM3_HUMAN

Porphobilinogen deaminase

0.376

CND2_HUMAN

Condensin complex subunit 2

0.376

HEM2_HUMAN

Delta-aminolevulinic acid dehydratase

0.377

HEM6_HUMAN

Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial

0.377

NADK_HUMAN

NAD kinase

0.377

TBC15_HUMAN

TBC1 domain family member 15

0.377

DCUP_HUMAN

Uroporphyrinogen decarboxylase

0.377

IPO9_HUMAN

Importin-9

0.378

PUR2_HUMAN

Trifunctional purine biosynthetic protein adenosine-3

0.378

UBP22_HUMAN

Ubiquitin carboxyl-terminal hydrolase 22

0.381

FGGY_HUMAN

FGGY carbohydrate kinase domain-containing protein

0.381

UBP10_HUMAN

Ubiquitin carboxyl-terminal hydrolase 10

0.381

CNIH4_HUMAN

Protein cornichon homolog 4

0.382

PUR1_HUMAN

Amidophosphoribosyltransferase

0.383

PUR9_HUMAN

Bifunctional purine biosynthesis protein PURH

0.383

NIT2_HUMAN

Omega-amidase NIT2

0.385

PICAL_HUMAN

Phosphatidylinositol-binding clathrin assembly protein

0.386

SERC_HUMAN

Phosphoserine aminotransferase

0.387

T2AG_HUMAN

Transcription initiation factor IIA subunit 2

0.387

HEMH_HUMAN

Ferrochelatase, mitochondrial

0.387

ATE1_HUMAN

Arginyl-tRNA--protein transferase 1

0.389

PI4KA_HUMAN

Phosphatidylinositol 4-kinase alpha

0.389

PDCL3_HUMAN

Phosducin-like protein 3

0.390

CCNB2_HUMAN

G2/mitotic-specific cyclin-B2

0.390

PDP1_HUMAN

[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial

0.390

TTC37_HUMAN

Tetratricopeptide repeat protein 37

0.390

RPN1_HUMAN

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

0.390

ARPC2_HUMAN

Actin-related protein 2/3 complex subunit 2

0.391

TBC17_HUMAN

TBC1 domain family member 17

0.391

ORC4_HUMAN

Origin recognition complex subunit 4

0.391

VPS8_HUMAN

Vacuolar protein sorting-associated protein 8 homolog

0.391

PPID_HUMAN

Peptidyl-prolyl cis-trans isomerase D

0.392

GNA1_HUMAN

Glucosamine 6-phosphate N-acetyltransferase

0.392

UBR7_HUMAN

Putative E3 ubiquitin-protein ligase UBR7

0.393

GATA_HUMAN

Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial

0.393

ARLY_HUMAN

Argininosuccinate lyase

0.393

PEX1_HUMAN

Peroxisome biogenesis factor 1

0.393

RNF10_HUMAN

RING finger protein 10

0.393

PANK4_HUMAN

Pantothenate kinase 4

0.393

HXK4_HUMAN

Glucokinase

0.393

VDAC2_HUMAN

Voltage-dependent anion-selective channel protein 2

0.393

NOP14_HUMAN

Nucleolar protein 14

0.393

ALDH2_HUMAN

Aldehyde dehydrogenase, mitochondrial

0.393

PUR4_HUMAN

Phosphoribosylformylglycinamidine synthase

0.393

PLST_HUMAN

Plastin-3

0.394

NADE_HUMAN

Glutamine-dependent NAD(+) synthetase

0.394

AP180_HUMAN

Clathrin coat assembly protein AP180

0.394

PYR1_HUMAN

CAD protein

0.394

WDR1_HUMAN

WD repeat-containing protein 1

0.394

TNPO3_HUMAN

Transportin-3

0.394

HXK1_HUMAN

Hexokinase-1

0.394

PLD1_HUMAN

Phospholipase D1

0.394

SNF5_HUMAN

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

0.395

RRP12_HUMAN

RRP12-like protein

0.395

HMDH_HUMAN

3-hydroxy-3-methylglutaryl-coenzyme A reductase

0.395

CND3_HUMAN

Condensin complex subunit 3

0.395

GNAO_HUMAN

Guanine nucleotide-binding protein G(o) subunit alpha

0.395

EXOC5_HUMAN

Exocyst complex component 5

0.395

PEX14_HUMAN

Peroxisomal membrane protein PEX14

0.396

CHMP3_HUMAN

Charged multivesicular body protein 3

0.396

B3A3_HUMAN

Anion exchange protein 3

0.396

BECN1_HUMAN

Beclin-1

0.396

CDC42_HUMAN

Cell division control protein 42 homolog

0.397

MIRO1_HUMAN

Mitochondrial Rho GTPase 1

0.397

MARH6_HUMAN

E3 ubiquitin-protein ligase MARCH6

0.397

RBBP5_HUMAN

Retinoblastoma-binding protein 5

0.397

HAOX1_HUMAN

Hydroxyacid oxidase 1

0.397

TMED2_HUMAN

Transmembrane emp24 domain-containing protein 2

0.397

BTAF1_HUMAN

TATA-binding protein-associated factor 172

0.397

IPO4_HUMAN

Importin-4

0.397

DHSO_HUMAN

Sorbitol dehydrogenase

0.397

FANCM_HUMAN

Fanconi anemia group M protein

0.397

VDAC1_HUMAN

Voltage-dependent anion-selective channel protein 1

0.397

S35F5_HUMAN

Solute carrier family 35 member F5

0.398

PIGS_HUMAN

GPI transamidase component PIG-S

0.398

LICH_HUMAN

Lysosomal acid lipase/cholesteryl ester hydrolase

0.398

RPAP1_HUMAN

RNA polymerase II-associated protein 1

0.398

GCSP_HUMAN

Glycine dehydrogenase (decarboxylating), mitochondrial

0.398

STK24_HUMAN

Serine/threonine-protein kinase 24

0.398

PIGT_HUMAN

GPI transamidase component PIG-T

0.398

BCS1_HUMAN

Mitochondrial chaperone BCS1

0.399

GDIR1_HUMAN

Rho GDP-dissociation inhibitor 1

0.399

MO4L1_HUMAN

Mortality factor 4-like protein 1

0.399

PISD_HUMAN

Phosphatidylserine decarboxylase proenzyme, mitochondrial

0.399

HMCS1_HUMAN

Hydroxymethylglutaryl-CoA synthase, cytoplasmic

0.399

PEX7_HUMAN

Peroxisomal targeting signal 2 receptor

0.399

NIPBL_HUMAN

Nipped-B-like protein

0.399

PLPP4_HUMAN

Phospholipid phosphatase 4

0.400

CHD1_HUMAN

Chromodomain-helicase-DNA-binding protein 1

0.400

NMNA1_HUMAN

Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1

0.400

CCNB1_HUMAN

G2/mitotic-specific cyclin-B1

0.400

HACL1_HUMAN

2-hydroxyacyl-CoA lyase 1

0.400

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 103 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy