ZNT10_HUMAN 2019

Gene Name ZNT10

Description Zinc transporter 10

Length 485

9606

Sequence

>sp|Q6XR72|ZNT10_HUMAN Zinc transporter 10
MGRYSGKTCRLLFMLVLTVAFFVAELVSGYLGNSIALLSDSFNMLSDLISLCVGLSAGYIARRPTRGFSATYGYARAEVVGALSNAVFLTALCFTIFVEAVLRLARPERIDDPELVLIVGVLGLLVNVVGLLIFQDCAAWFACCLRGRSRRLQQRQQLAEGCVPGAFGGPQGAEDPRRAADPTAPGSDSAVTLRGTSVERKREKGATVFANVAGDSFNTQNEPEDMMKKEKKSEALNIRGVLLHVMGDALGSVVVVITAIIFYVLPLKSEDPCNWQCYIDPSLTVLMVIIILSSAFPLIKETAAILLQMVPKGVNMEELMSKLSAVPGISSVHEVHIWELVSGKIIATLHIKYPKDRGYQDASTKIREIFHHAGIHNVTIQFENVDLKEPLEQKDLLLLCNSPCISKGCAKQLCCPPGALPLAHVNGCAEHNGGPSLDTYGSDGLSRRDAREVAIEVSLDSCLSDHGQSLNKTQEDQCYVNRTHF

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

No protein with similar profile across the domains were found

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

ZNT1_HUMAN

Zinc transporter 1

0.281

PAK2_HUMAN

Serine/threonine-protein kinase PAK 2

0.359

AL4A1_HUMAN

Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial

0.363

PAK1_HUMAN

Serine/threonine-protein kinase PAK 1

0.363

PAK3_HUMAN

Serine/threonine-protein kinase PAK 3

0.363

GOLP3_HUMAN

Golgi phosphoprotein 3

0.365

CLCN5_HUMAN

H(+)/Cl(-) exchange transporter 5

0.365

CLCN4_HUMAN

H(+)/Cl(-) exchange transporter 4

0.365

SLMAP_HUMAN

Sarcolemmal membrane-associated protein

0.366

DPOG1_HUMAN

DNA polymerase subunit gamma-1

0.366

PBDC1_HUMAN

Protein PBDC1

0.368

VIGLN_HUMAN

Vigilin

0.369

CLCN3_HUMAN

H(+)/Cl(-) exchange transporter 3

0.372

COX5A_HUMAN

Cytochrome c oxidase subunit 5A, mitochondrial

0.374

SYNC_HUMAN

Asparagine--tRNA ligase, cytoplasmic

0.374

GYS2_HUMAN

Glycogen [starch] synthase, liver

0.376

SEPR_HUMAN

Prolyl endopeptidase FAP

0.376

SYRM_HUMAN

Probable arginine--tRNA ligase, mitochondrial

0.377

SURF4_HUMAN

Surfeit locus protein 4

0.378

SOS1_HUMAN

Son of sevenless homolog 1

0.378

HIP1_HUMAN

Huntingtin-interacting protein 1

0.378

HIP1R_HUMAN

Huntingtin-interacting protein 1-related protein

0.380

GLP3L_HUMAN

Golgi phosphoprotein 3-like

0.381

DPP4_HUMAN

Dipeptidyl peptidase 4

0.382

GATA3_HUMAN

Trans-acting T-cell-specific transcription factor GATA-3

0.382

GDE_HUMAN

Glycogen debranching enzyme

0.383

CMC1_HUMAN

Calcium-binding mitochondrial carrier protein Aralar1

0.386

SRF_HUMAN

Serum response factor

0.386

DPP10_HUMAN

Inactive dipeptidyl peptidase 10

0.387

CUL1_HUMAN

Cullin-1

0.387

S39A9_HUMAN

Zinc transporter ZIP9

0.388

IQGA1_HUMAN

Ras GTPase-activating-like protein IQGAP1

0.389

DOCK3_HUMAN

Dedicator of cytokinesis protein 3

0.389

SOS2_HUMAN

Son of sevenless homolog 2

0.389

DOCK5_HUMAN

Dedicator of cytokinesis protein 5

0.390

GATA4_HUMAN

Transcription factor GATA-4

0.390

GYS1_HUMAN

Glycogen [starch] synthase, muscle

0.390

NPRL2_HUMAN

GATOR complex protein NPRL2

0.392

ACON_HUMAN

Aconitate hydratase, mitochondrial

0.392

AVL9_HUMAN

Late secretory pathway protein AVL9 homolog

0.392

TRM44_HUMAN

Probable tRNA (uracil-O(2)-)-methyltransferase

0.393

TM9S2_HUMAN

Transmembrane 9 superfamily member 2

0.393

PP2BB_HUMAN

Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform

0.393

AT2C2_HUMAN

Calcium-transporting ATPase type 2C member 2

0.394

GATA2_HUMAN

Endothelial transcription factor GATA-2

0.395

PAN3_HUMAN

PAN2-PAN3 deadenylation complex subunit PAN3

0.395

STRP1_HUMAN

Striatin-interacting protein 1

0.396

S2536_HUMAN

Solute carrier family 25 member 36

0.396

SEPT7_HUMAN

Septin-7

0.396

LIS1_HUMAN

Platelet-activating factor acetylhydrolase IB subunit alpha

0.397

DOP1_HUMAN

Protein dopey-1

0.397

TOM70_HUMAN

Mitochondrial import receptor subunit TOM70

0.397

DOT1L_HUMAN

Histone-lysine N-methyltransferase, H3 lysine-79 specific

0.398

DOP2_HUMAN

Protein dopey-2

0.398

PP2BA_HUMAN

Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform

0.399

RAGP1_HUMAN

Ran GTPase-activating protein 1

0.400

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 83 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy