MOGT3_HUMAN 2019

Gene Name MOGT3

Description 2-acylglycerol O-acyltransferase 3

Length 341

9606

Sequence

>sp|Q86VF5|MOGT3_HUMAN 2-acylglycerol O-acyltransferase 3
MGVATTLQPPTTSKTLQKQHLEAVGAYQYVLTFLFMGPFFSLLVFVLLFTSLWPFSVFYLVWLYVDWDTPNQGGRRSEWIRNRAIWRQLRDYYPVKLVKTAELPPDRNYVLGAHPHGIMCTGFLCNFSTESNGFSQLFPGLRPWLAVLAGLFYLPVYRDYIMSFGLCPVSRQSLDFILSQPQLGQAVVIMVGGAHEALYSVPGEHCLTLQKRKGFVRLALRHGASLVPVYSFGENDIFRLKAFATGSWQHWCQLTFKKLMGFSPCIFWGRGLFSATSWGLLPFAVPITTVVGRPIPVPQRLHPTEEEVNHYHALYMTALEQLFEEHKESCGVPASTCLTFI

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

DG2L6_HUMAN

Diacylglycerol O-acyltransferase 2-like protein 6

0.361

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

MOGT1_HUMAN

2-acylglycerol O-acyltransferase 1

0.322

DGAT2_HUMAN

Diacylglycerol O-acyltransferase 2

0.323

DG2L6_HUMAN

Diacylglycerol O-acyltransferase 2-like protein 6

0.333

MOGT2_HUMAN

2-acylglycerol O-acyltransferase 2

0.342

AWAT2_HUMAN

Acyl-CoA wax alcohol acyltransferase 2

0.352

AL1B1_HUMAN

Aldehyde dehydrogenase X, mitochondrial

0.360

ALAT1_HUMAN

Alanine aminotransferase 1

0.368

BCAT2_HUMAN

Branched-chain-amino-acid aminotransferase, mitochondrial

0.371

FMO2_HUMAN

Dimethylaniline monooxygenase [N-oxide-forming] 2

0.373

AWAT1_HUMAN

Acyl-CoA wax alcohol acyltransferase 1

0.373

NB5R2_HUMAN

NADH-cytochrome b5 reductase 2

0.375

KCC1B_HUMAN

Calcium/calmodulin-dependent protein kinase type 1B

0.377

FMO1_HUMAN

Dimethylaniline monooxygenase [N-oxide-forming] 1

0.377

MAOX_HUMAN

NADP-dependent malic enzyme

0.379

FMO4_HUMAN

Dimethylaniline monooxygenase [N-oxide-forming] 4

0.380

AT2B3_HUMAN

Plasma membrane calcium-transporting ATPase 3

0.381

H2B3B_HUMAN

Histone H2B type 3-B

0.382

S14L5_HUMAN

SEC14-like protein 5

0.382

AAKG3_HUMAN

5-AMP-activated protein kinase subunit gamma-3

0.383

FMO3_HUMAN

Dimethylaniline monooxygenase [N-oxide-forming] 3

0.383

F16P2_HUMAN

Fructose-1,6-bisphosphatase isozyme 2

0.385

PDCL2_HUMAN

Phosducin-like protein 2

0.386

STAG3_HUMAN

Cohesin subunit SA-3

0.388

NB5R1_HUMAN

NADH-cytochrome b5 reductase 1

0.388

ATP7B_HUMAN

Copper-transporting ATPase 2

0.388

LIPN_HUMAN

Lipase member N

0.389

GANC_HUMAN

Neutral alpha-glucosidase C

0.390

LIPJ_HUMAN

Lipase member J

0.390

HMCS2_HUMAN

Hydroxymethylglutaryl-CoA synthase, mitochondrial

0.391

PDK4_HUMAN

[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial

0.391

LIPG_HUMAN

Gastric triacylglycerol lipase

0.391

FMO6_HUMAN

Putative dimethylaniline monooxygenase [N-oxide-forming] 6

0.392

LIPK_HUMAN

Lipase member K

0.392

HS105_HUMAN

Heat shock protein 105 kDa

0.392

AP1G2_HUMAN

AP-1 complex subunit gamma-like 2

0.393

PAQR2_HUMAN

Adiponectin receptor protein 2

0.393

ALDR_HUMAN

Aldo-keto reductase family 1 member B1

0.394

RD21L_HUMAN

Double-strand-break repair protein rad21-like protein 1

0.394

H2B1A_HUMAN

Histone H2B type 1-A

0.394

TCPW_HUMAN

T-complex protein 1 subunit zeta-2

0.394

P5CS_HUMAN

Delta-1-pyrroline-5-carboxylate synthase

0.395

NAA16_HUMAN

N-alpha-acetyltransferase 16, NatA auxiliary subunit

0.395

S36A3_HUMAN

Proton-coupled amino acid transporter 3

0.395

HEMH_HUMAN

Ferrochelatase, mitochondrial

0.395

F261_HUMAN

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1

0.396

AT2B4_HUMAN

Plasma membrane calcium-transporting ATPase 4

0.396

TKTL2_HUMAN

Transketolase-like protein 2

0.396

S14L4_HUMAN

SEC14-like protein 4

0.396

DX39A_HUMAN

ATP-dependent RNA helicase DDX39A

0.397

MO4L2_HUMAN

Mortality factor 4-like protein 2

0.397

COQ8B_HUMAN

Atypical kinase COQ8B, mitochondrial

0.397

ANM1_HUMAN

Protein arginine N-methyltransferase 1

0.397

2AAB_HUMAN

Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

0.398

SPEE_HUMAN

Spermidine synthase

0.398

PLPP5_HUMAN

Phospholipid phosphatase 5

0.398

CBSL_HUMAN

Cystathionine beta-synthase-like protein

0.398

CBS_HUMAN

Cystathionine beta-synthase

0.398

VATE2_HUMAN

V-type proton ATPase subunit E 2

0.398

CLH2_HUMAN

Clathrin heavy chain 2

0.398

AAKG1_HUMAN

5-AMP-activated protein kinase subunit gamma-1

0.398

HEM6_HUMAN

Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial

0.398

GSK3A_HUMAN

Glycogen synthase kinase-3 alpha

0.398

ASF1B_HUMAN

Histone chaperone ASF1B

0.399

F16P1_HUMAN

Fructose-1,6-bisphosphatase 1

0.399

MOB1B_HUMAN

MOB kinase activator 1B

0.399

KPYR_HUMAN

Pyruvate kinase PKLR

0.399

HDAC1_HUMAN

Histone deacetylase 1

0.399

ALAT2_HUMAN

Alanine aminotransferase 2

0.399

H2AJ_HUMAN

Histone H2A.J

0.400

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 110 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy