UB2J1_HUMAN 2019

Gene Name UB2J1

Description Ubiquitin-conjugating enzyme E2 J1

Length 318

9606

Sequence

>sp|Q9Y385|UB2J1_HUMAN Ubiquitin-conjugating enzyme E2 J1
METRYNLKSPAVKRLMKEAAELKDPTDHYHAQPLEDNLFEWHFTVRGPPDSDFDGGVYHGRIVLPPEYPMKPPSIILLTANGRFEVGKKICLSISGHHPETWQPSWSIRTALLAIIGFMPTKGEGAIGSLDYTPEERRALAKKSQDFCCEGCGSAMKDVLLPLKSGSDSSQADQEAKELARQISFKAEVNSSGKTISESDLNHSFSLTDLQDDIPTTFQGATASTSYGLQNSSAASFHQPTQPVAKNTSMSPRQRRAQQQSQRRLSTSPDVIQGHQPRDNHTDHGGSAVLIVILTLALAALIFRRIYLANEYIFDFEL

Domains

Loading...

Help

What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

SNAB_HUMAN

Beta-soluble NSF attachment protein

0.366

VPS35_HUMAN

Vacuolar protein sorting-associated protein 35

0.366

SEC13_HUMAN

Protein SEC13 homolog

0.372

SNAA_HUMAN

Alpha-soluble NSF attachment protein

0.374

CLH1_HUMAN

Clathrin heavy chain 1

0.374

DIEXF_HUMAN

Digestive organ expansion factor homolog

0.376

MTOR_HUMAN

Serine/threonine-protein kinase mTOR

0.376

TPPC5_HUMAN

Trafficking protein particle complex subunit 5

0.376

UBP13_HUMAN

Ubiquitin carboxyl-terminal hydrolase 13

0.376

EIF3D_HUMAN

Eukaryotic translation initiation factor 3 subunit D

0.377

EIF3E_HUMAN

Eukaryotic translation initiation factor 3 subunit E

0.377

CAP1_HUMAN

Adenylyl cyclase-associated protein 1

0.377

AP2B1_HUMAN

AP-2 complex subunit beta

0.382

PSA1_HUMAN

Proteasome subunit alpha type-1

0.382

BOP1_HUMAN

Ribosome biogenesis protein BOP1

0.382

U2AF5_HUMAN

Splicing factor U2AF 35 kDa subunit-like protein

0.383

U2AF1_HUMAN

Splicing factor U2AF 35 kDa subunit

0.383

U3IP2_HUMAN

U3 small nucleolar RNA-interacting protein 2

0.384

FNTA_HUMAN

Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

0.384

EMC3_HUMAN

ER membrane protein complex subunit 3

0.385

RPF2_HUMAN

Ribosome production factor 2 homolog

0.386

COPB_HUMAN

Coatomer subunit beta

0.386

RTF2_HUMAN

Replication termination factor 2

0.386

CRNL1_HUMAN

Crooked neck-like protein 1

0.389

SF3B1_HUMAN

Splicing factor 3B subunit 1

0.389

EIF3B_HUMAN

Eukaryotic translation initiation factor 3 subunit B

0.389

TPPC4_HUMAN

Trafficking protein particle complex subunit 4

0.390

H2B1C_HUMAN

Histone H2B type 1-C/E/F/G/I

0.390

BYST_HUMAN

Bystin

0.390

SSF1_HUMAN

Suppressor of SWI4 1 homolog

0.390

SF3B3_HUMAN

Splicing factor 3B subunit 3

0.390

NUP98_HUMAN

Nuclear pore complex protein Nup98-Nup96

0.391

UTP11_HUMAN

Probable U3 small nucleolar RNA-associated protein 11

0.391

RAB6A_HUMAN

Ras-related protein Rab-6A

0.391

PA2G4_HUMAN

Proliferation-associated protein 2G4

0.392

AP1G1_HUMAN

AP-1 complex subunit gamma-1

0.392

RAN_HUMAN

GTP-binding nuclear protein Ran

0.393

BRX1_HUMAN

Ribosome biogenesis protein BRX1 homolog

0.393

HM13_HUMAN

Minor histocompatibility antigen H13

0.393

CDC73_HUMAN

Parafibromin

0.393

PSMD3_HUMAN

26S proteasome non-ATPase regulatory subunit 3

0.394

UBP5_HUMAN

Ubiquitin carboxyl-terminal hydrolase 5

0.394

NSF_HUMAN

Vesicle-fusing ATPase

0.394

RBM19_HUMAN

Probable RNA-binding protein 19

0.394

PAPOG_HUMAN

Poly(A) polymerase gamma

0.394

CDC5L_HUMAN

Cell division cycle 5-like protein

0.394

UGGG1_HUMAN

UDP-glucose:glycoprotein glucosyltransferase 1

0.395

TMEDA_HUMAN

Transmembrane emp24 domain-containing protein 10

0.395

HEAT1_HUMAN

HEAT repeat-containing protein 1

0.395

TBL3_HUMAN

Transducin beta-like protein 3

0.395

PAPOA_HUMAN

Poly(A) polymerase alpha

0.395

PSA6_HUMAN

Proteasome subunit alpha type-6

0.395

GSK3B_HUMAN

Glycogen synthase kinase-3 beta

0.395

SF3A3_HUMAN

Splicing factor 3A subunit 3

0.395

CALM1_HUMAN

Calmodulin-1

0.397

PLRG1_HUMAN

Pleiotropic regulator 1

0.397

CALM2_HUMAN

Calmodulin-2

0.397

DBR1_HUMAN

Lariat debranching enzyme

0.397

A0A0B4J2E5_HUMAN

Uncharacterized protein

0.397

TCPQ_HUMAN

T-complex protein 1 subunit theta

0.397

RAB7A_HUMAN

Ras-related protein Rab-7a

0.398

NAA15_HUMAN

N-alpha-acetyltransferase 15, NatA auxiliary subunit

0.398

SPT6H_HUMAN

Transcription elongation factor SPT6

0.398

H2B2F_HUMAN

Histone H2B type 2-F

0.398

PFD3_HUMAN

Prefoldin subunit 3

0.398

H2B1D_HUMAN

Histone H2B type 1-D

0.398

RS12_HUMAN

40S ribosomal protein S12

0.398

H2B1K_HUMAN

Histone H2B type 1-K

0.398

STX16_HUMAN

Syntaxin-16

0.399

UBP14_HUMAN

Ubiquitin carboxyl-terminal hydrolase 14

0.399

TPPC3_HUMAN

Trafficking protein particle complex subunit 3

0.399

SNW1_HUMAN

SNW domain-containing protein 1

0.399

DYL2_HUMAN

Dynein light chain 2, cytoplasmic

0.399

ALG1_HUMAN

Chitobiosyldiphosphodolichol beta-mannosyltransferase

0.399

RPAB3_HUMAN

DNA-directed RNA polymerases I, II, and III subunit RPABC3

0.399

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

AT2A2_HUMAN

Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

0.357

ACPH_HUMAN

Acylamino-acid-releasing enzyme

0.366

EIF3L_HUMAN

Eukaryotic translation initiation factor 3 subunit L

0.367

EIF3E_HUMAN

Eukaryotic translation initiation factor 3 subunit E

0.368

EIF3D_HUMAN

Eukaryotic translation initiation factor 3 subunit D

0.370

RBM39_HUMAN

RNA-binding protein 39

0.373

NUDC_HUMAN

Nuclear migration protein nudC

0.373

CATIN_HUMAN

Cactin

0.376

CSN1_HUMAN

COP9 signalosome complex subunit 1

0.376

PPWD1_HUMAN

Peptidylprolyl isomerase domain and WD repeat-containing protein 1

0.377

CHRD1_HUMAN

Cysteine and histidine-rich domain-containing protein 1

0.378

ACLY_HUMAN

ATP-citrate synthase

0.381

AT2A1_HUMAN

Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

0.383

PPIL2_HUMAN

RING-type E3 ubiquitin-protein ligase PPIL2

0.383

KDM8_HUMAN

Bifunctional peptidase and arginyl-hydroxylase JMJD5

0.383

FAN1_HUMAN

Fanconi-associated nuclease 1

0.383

GPTC1_HUMAN

G patch domain-containing protein 1

0.384

HCDH_HUMAN

Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial

0.387

CLPT1_HUMAN

Cleft lip and palate transmembrane protein 1

0.388

EIF3M_HUMAN

Eukaryotic translation initiation factor 3 subunit M

0.389

PIMT_HUMAN

Protein-L-isoaspartate(D-aspartate) O-methyltransferase

0.389

U5S1_HUMAN

116 kDa U5 small nuclear ribonucleoprotein component

0.390

NDUV2_HUMAN

NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

0.391

CTBL1_HUMAN

Beta-catenin-like protein 1

0.392

ODBA_HUMAN

2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial

0.392

EIF3K_HUMAN

Eukaryotic translation initiation factor 3 subunit K

0.393

CSN4_HUMAN

COP9 signalosome complex subunit 4

0.394

ODBB_HUMAN

2-oxoisovalerate dehydrogenase subunit beta, mitochondrial

0.394

DDB1_HUMAN

DNA damage-binding protein 1

0.394

DNJC3_HUMAN

DnaJ homolog subfamily C member 3

0.395

CCD12_HUMAN

Coiled-coil domain-containing protein 12

0.395

ARL8B_HUMAN

ADP-ribosylation factor-like protein 8B

0.396

NDUV1_HUMAN

NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

0.397

CHDH_HUMAN

Choline dehydrogenase, mitochondrial

0.397

CSN7B_HUMAN

COP9 signalosome complex subunit 7b

0.397

MCCB_HUMAN

Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

0.398

AT2A3_HUMAN

Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

0.399

EMC2_HUMAN

ER membrane protein complex subunit 2

0.399

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 137 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy