RPP29_HUMAN 2019

Gene Name RPP29

Description Ribonuclease P protein subunit p29

Length 220

9606

Sequence

>sp|O95707|RPP29_HUMAN Ribonuclease P protein subunit p29
MKSVIYHALSQKEANDSDVQPSGAQRAEAFVRAFLKRSTPRMSPQAREDQLQRKAVVLEYFTRHKRKEKKKKAKGLSARQRRELRLFDIKPEQQRYSLFLPLHELWKQYIRDLCSGLKPDTQPQMIQAKLLKADLHGAIISVTKSKCPSYVGITGILLQETKHIFKIITKEDRLKVIPKLNCVFTVETDGFISYIYGSKFQLRSSERSAKKFKAKGTIDL

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

KDM5A_HUMAN

Lysine-specific demethylase 5A

0.365

RBP10_HUMAN

Ran-binding protein 10

0.368

RANB9_HUMAN

Ran-binding protein 9

0.369

TI17A_HUMAN

Mitochondrial import inner membrane translocase subunit Tim17-A

0.374

EIF3F_HUMAN

Eukaryotic translation initiation factor 3 subunit F

0.375

MAEA_HUMAN

E3 ubiquitin-protein transferase MAEA

0.377

OST48_HUMAN

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

0.378

VAPA_HUMAN

Vesicle-associated membrane protein-associated protein A

0.380

ZC3HF_HUMAN

Zinc finger CCCH domain-containing protein 15

0.382

PWP2_HUMAN

Periodic tryptophan protein 2 homolog

0.383

HAT1_HUMAN

Histone acetyltransferase type B catalytic subunit

0.383

TAM41_HUMAN

Phosphatidate cytidylyltransferase, mitochondrial

0.383

VAPB_HUMAN

Vesicle-associated membrane protein-associated protein B/C

0.384

ORC4_HUMAN

Origin recognition complex subunit 4

0.384

UB2V2_HUMAN

Ubiquitin-conjugating enzyme E2 variant 2

0.385

PRP4_HUMAN

U4/U6 small nuclear ribonucleoprotein Prp4

0.386

AP1S2_HUMAN

AP-1 complex subunit sigma-2

0.386

DAD1_HUMAN

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

0.387

DMAP1_HUMAN

DNA methyltransferase 1-associated protein 1

0.388

FIG4_HUMAN

Polyphosphoinositide phosphatase

0.389

ORC2_HUMAN

Origin recognition complex subunit 2

0.389

A0A0B4J2E5_HUMAN

Uncharacterized protein

0.390

VPS35_HUMAN

Vacuolar protein sorting-associated protein 35

0.390

TI17B_HUMAN

Mitochondrial import inner membrane translocase subunit Tim17-B

0.392

KDM5B_HUMAN

Lysine-specific demethylase 5B

0.392

CWC15_HUMAN

Spliceosome-associated protein CWC15 homolog

0.392

PP6R3_HUMAN

Serine/threonine-protein phosphatase 6 regulatory subunit 3

0.392

BUD13_HUMAN

BUD13 homolog

0.392

SNW1_HUMAN

SNW domain-containing protein 1

0.392

UBP7_HUMAN

Ubiquitin carboxyl-terminal hydrolase 7

0.392

RPN1_HUMAN

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

0.393

CHMP6_HUMAN

Charged multivesicular body protein 6

0.393

LETM1_HUMAN

Mitochondrial proton/calcium exchanger protein

0.393

GID8_HUMAN

Glucose-induced degradation protein 8 homolog

0.396

UBP12_HUMAN

Ubiquitin carboxyl-terminal hydrolase 12

0.396

PIGT_HUMAN

GPI transamidase component PIG-T

0.397

CLH1_HUMAN

Clathrin heavy chain 1

0.398

GPAA1_HUMAN

Glycosylphosphatidylinositol anchor attachment 1 protein

0.398

EIF3H_HUMAN

Eukaryotic translation initiation factor 3 subunit H

0.399

BT3L4_HUMAN

Transcription factor BTF3 homolog 4

0.399

VPS18_HUMAN

Vacuolar protein sorting-associated protein 18 homolog

0.399

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

KDM5A_HUMAN

Lysine-specific demethylase 5A

0.365

RBP10_HUMAN

Ran-binding protein 10

0.368

RANB9_HUMAN

Ran-binding protein 9

0.369

TI17A_HUMAN

Mitochondrial import inner membrane translocase subunit Tim17-A

0.374

EIF3F_HUMAN

Eukaryotic translation initiation factor 3 subunit F

0.375

MAEA_HUMAN

E3 ubiquitin-protein transferase MAEA

0.377

OST48_HUMAN

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

0.378

VAPA_HUMAN

Vesicle-associated membrane protein-associated protein A

0.380

ZC3HF_HUMAN

Zinc finger CCCH domain-containing protein 15

0.382

PWP2_HUMAN

Periodic tryptophan protein 2 homolog

0.383

HAT1_HUMAN

Histone acetyltransferase type B catalytic subunit

0.383

TAM41_HUMAN

Phosphatidate cytidylyltransferase, mitochondrial

0.383

VAPB_HUMAN

Vesicle-associated membrane protein-associated protein B/C

0.384

ORC4_HUMAN

Origin recognition complex subunit 4

0.384

UB2V2_HUMAN

Ubiquitin-conjugating enzyme E2 variant 2

0.385

PRP4_HUMAN

U4/U6 small nuclear ribonucleoprotein Prp4

0.386

AP1S2_HUMAN

AP-1 complex subunit sigma-2

0.386

DAD1_HUMAN

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

0.387

DMAP1_HUMAN

DNA methyltransferase 1-associated protein 1

0.388

FIG4_HUMAN

Polyphosphoinositide phosphatase

0.389

ORC2_HUMAN

Origin recognition complex subunit 2

0.389

A0A0B4J2E5_HUMAN

Uncharacterized protein

0.390

VPS35_HUMAN

Vacuolar protein sorting-associated protein 35

0.390

TI17B_HUMAN

Mitochondrial import inner membrane translocase subunit Tim17-B

0.392

KDM5B_HUMAN

Lysine-specific demethylase 5B

0.392

CWC15_HUMAN

Spliceosome-associated protein CWC15 homolog

0.392

PP6R3_HUMAN

Serine/threonine-protein phosphatase 6 regulatory subunit 3

0.392

BUD13_HUMAN

BUD13 homolog

0.392

SNW1_HUMAN

SNW domain-containing protein 1

0.392

UBP7_HUMAN

Ubiquitin carboxyl-terminal hydrolase 7

0.392

RPN1_HUMAN

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

0.393

CHMP6_HUMAN

Charged multivesicular body protein 6

0.393

LETM1_HUMAN

Mitochondrial proton/calcium exchanger protein

0.393

GID8_HUMAN

Glucose-induced degradation protein 8 homolog

0.396

UBP12_HUMAN

Ubiquitin carboxyl-terminal hydrolase 12

0.396

PIGT_HUMAN

GPI transamidase component PIG-T

0.397

CLH1_HUMAN

Clathrin heavy chain 1

0.398

GPAA1_HUMAN

Glycosylphosphatidylinositol anchor attachment 1 protein

0.398

EIF3H_HUMAN

Eukaryotic translation initiation factor 3 subunit H

0.399

BT3L4_HUMAN

Transcription factor BTF3 homolog 4

0.399

VPS18_HUMAN

Vacuolar protein sorting-associated protein 18 homolog

0.399

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 136 organisms (of 369)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy