DJB14_HUMAN 2019

Gene Name DJB14

Description DnaJ homolog subfamily B member 14

Length 379

9606

Sequence

>sp|Q8TBM8|DJB14_HUMAN DnaJ homolog subfamily B member 14
MEGNRDEAEKCVEIAREALNAGNREKAQRFLQKAEKLYPLPSARALLEIIMKNGSTAGNSPHCRKPSGSGDQSKPNCTKDSTSGSGEGGKGYTKDQVDGVLSINKCKNYYEVLGVTKDAGDEDLKKAYRKLALKFHPDKNHAPGATDAFKKIGNAYAVLSNPEKRKQYDLTGNEEQACNHQNNGRFNFHRGCEADITPEDLFNIFFGGGFPSGSVHSFSNGRAGYSQQHQHRHSGHEREEERGDGGFSVFIQLMPIIVLILVSLLSQLMVSNPPYSLYPRSGTGQTIKMQTENLGVVYYVNKDFKNEYKGMLLQKVEKSVEEDYVTNIRNNCWKERQQKTDMQYAAKVYRDDRLRRKADALSMDNCKELERLTSLYKGG

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

DJB12_HUMAN

DnaJ homolog subfamily B member 12

0.208

CTBL1_HUMAN

Beta-catenin-like protein 1

0.349

EIF3E_HUMAN

Eukaryotic translation initiation factor 3 subunit E

0.370

KIN17_HUMAN

DNA/RNA-binding protein KIN17

0.370

PRP4_HUMAN

U4/U6 small nuclear ribonucleoprotein Prp4

0.372

DMAP1_HUMAN

DNA methyltransferase 1-associated protein 1

0.373

TFP11_HUMAN

Tuftelin-interacting protein 11

0.378

EIFCL_HUMAN

Eukaryotic translation initiation factor 3 subunit C-like protein

0.378

SNW1_HUMAN

SNW domain-containing protein 1

0.378

EIF3C_HUMAN

Eukaryotic translation initiation factor 3 subunit C

0.378

LETM1_HUMAN

Mitochondrial proton/calcium exchanger protein

0.379

MFRN2_HUMAN

Mitoferrin-2

0.380

COPZ1_HUMAN

Coatomer subunit zeta-1

0.380

U2AF2_HUMAN

Splicing factor U2AF 65 kDa subunit

0.382

VAC14_HUMAN

Protein VAC14 homolog

0.382

RBM22_HUMAN

Pre-mRNA-splicing factor RBM22

0.382

ZC3HF_HUMAN

Zinc finger CCCH domain-containing protein 15

0.383

SF3B3_HUMAN

Splicing factor 3B subunit 3

0.384

PRP17_HUMAN

Pre-mRNA-processing factor 17

0.384

RAB6A_HUMAN

Ras-related protein Rab-6A

0.385

VPS53_HUMAN

Vacuolar protein sorting-associated protein 53 homolog

0.385

BT3L4_HUMAN

Transcription factor BTF3 homolog 4

0.385

VPS18_HUMAN

Vacuolar protein sorting-associated protein 18 homolog

0.385

RBM8A_HUMAN

RNA-binding protein 8A

0.386

PRP6_HUMAN

Pre-mRNA-processing factor 6

0.386

EIF3A_HUMAN

Eukaryotic translation initiation factor 3 subunit A

0.386

PA2G4_HUMAN

Proliferation-associated protein 2G4

0.386

AP1S2_HUMAN

AP-1 complex subunit sigma-2

0.388

PRP19_HUMAN

Pre-mRNA-processing factor 19

0.388

SNUT2_HUMAN

U4/U6.U5 tri-snRNP-associated protein 2

0.388

P4K2B_HUMAN

Phosphatidylinositol 4-kinase type 2-beta

0.390

P4R3A_HUMAN

Serine/threonine-protein phosphatase 4 regulatory subunit 3A

0.390

ORC2_HUMAN

Origin recognition complex subunit 2

0.390

DPOA2_HUMAN

DNA polymerase alpha subunit B

0.390

VPS35_HUMAN

Vacuolar protein sorting-associated protein 35

0.391

PLRG1_HUMAN

Pleiotropic regulator 1

0.391

DBR1_HUMAN

Lariat debranching enzyme

0.391

CC130_HUMAN

Coiled-coil domain-containing protein 130

0.392

TI17A_HUMAN

Mitochondrial import inner membrane translocase subunit Tim17-A

0.392

RAB7A_HUMAN

Ras-related protein Rab-7a

0.392

NAA15_HUMAN

N-alpha-acetyltransferase 15, NatA auxiliary subunit

0.392

EIF3F_HUMAN

Eukaryotic translation initiation factor 3 subunit F

0.393

CWC15_HUMAN

Spliceosome-associated protein CWC15 homolog

0.393

VPS36_HUMAN

Vacuolar protein-sorting-associated protein 36

0.393

BUD13_HUMAN

BUD13 homolog

0.393

STX16_HUMAN

Syntaxin-16

0.393

FNTB_HUMAN

Protein farnesyltransferase subunit beta

0.393

NSF1C_HUMAN

NSFL1 cofactor p47

0.393

BTF3_HUMAN

Transcription factor BTF3

0.393

TPPC3_HUMAN

Trafficking protein particle complex subunit 3

0.393

UBP14_HUMAN

Ubiquitin carboxyl-terminal hydrolase 14

0.393

FNTA_HUMAN

Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

0.393

ASTRB_HUMAN

Protein Aster-B

0.394

RPN1_HUMAN

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

0.394

MAEA_HUMAN

E3 ubiquitin-protein transferase MAEA

0.394

CTDP1_HUMAN

RNA polymerase II subunit A C-terminal domain phosphatase

0.395

TPPC8_HUMAN

Trafficking protein particle complex subunit 8

0.396

RTF2_HUMAN

Replication termination factor 2

0.396

MFRN1_HUMAN

Mitoferrin-1

0.397

CATD_HUMAN

Cathepsin D

0.397

SNR40_HUMAN

U5 small nuclear ribonucleoprotein 40 kDa protein

0.397

SF3B1_HUMAN

Splicing factor 3B subunit 1

0.398

EIF3B_HUMAN

Eukaryotic translation initiation factor 3 subunit B

0.398

CRNL1_HUMAN

Crooked neck-like protein 1

0.398

KDM5A_HUMAN

Lysine-specific demethylase 5A

0.399

PRPF3_HUMAN

U4/U6 small nuclear ribonucleoprotein Prp3

0.399

CLH1_HUMAN

Clathrin heavy chain 1

0.399

SMD3_HUMAN

Small nuclear ribonucleoprotein Sm D3

0.399

XPO2_HUMAN

Exportin-2

0.399

BYST_HUMAN

Bystin

0.399

TAM41_HUMAN

Phosphatidate cytidylyltransferase, mitochondrial

0.400

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

DJB12_HUMAN

DnaJ homolog subfamily B member 12

0.208

CTBL1_HUMAN

Beta-catenin-like protein 1

0.349

EIF3E_HUMAN

Eukaryotic translation initiation factor 3 subunit E

0.370

KIN17_HUMAN

DNA/RNA-binding protein KIN17

0.370

PRP4_HUMAN

U4/U6 small nuclear ribonucleoprotein Prp4

0.372

DMAP1_HUMAN

DNA methyltransferase 1-associated protein 1

0.373

TFP11_HUMAN

Tuftelin-interacting protein 11

0.378

EIFCL_HUMAN

Eukaryotic translation initiation factor 3 subunit C-like protein

0.378

SNW1_HUMAN

SNW domain-containing protein 1

0.378

EIF3C_HUMAN

Eukaryotic translation initiation factor 3 subunit C

0.378

LETM1_HUMAN

Mitochondrial proton/calcium exchanger protein

0.379

MFRN2_HUMAN

Mitoferrin-2

0.380

COPZ1_HUMAN

Coatomer subunit zeta-1

0.380

U2AF2_HUMAN

Splicing factor U2AF 65 kDa subunit

0.382

VAC14_HUMAN

Protein VAC14 homolog

0.382

RBM22_HUMAN

Pre-mRNA-splicing factor RBM22

0.382

ZC3HF_HUMAN

Zinc finger CCCH domain-containing protein 15

0.383

SF3B3_HUMAN

Splicing factor 3B subunit 3

0.384

PRP17_HUMAN

Pre-mRNA-processing factor 17

0.384

RAB6A_HUMAN

Ras-related protein Rab-6A

0.385

VPS53_HUMAN

Vacuolar protein sorting-associated protein 53 homolog

0.385

BT3L4_HUMAN

Transcription factor BTF3 homolog 4

0.385

VPS18_HUMAN

Vacuolar protein sorting-associated protein 18 homolog

0.385

RBM8A_HUMAN

RNA-binding protein 8A

0.386

PRP6_HUMAN

Pre-mRNA-processing factor 6

0.386

EIF3A_HUMAN

Eukaryotic translation initiation factor 3 subunit A

0.386

PA2G4_HUMAN

Proliferation-associated protein 2G4

0.386

AP1S2_HUMAN

AP-1 complex subunit sigma-2

0.388

PRP19_HUMAN

Pre-mRNA-processing factor 19

0.388

SNUT2_HUMAN

U4/U6.U5 tri-snRNP-associated protein 2

0.388

P4K2B_HUMAN

Phosphatidylinositol 4-kinase type 2-beta

0.390

P4R3A_HUMAN

Serine/threonine-protein phosphatase 4 regulatory subunit 3A

0.390

ORC2_HUMAN

Origin recognition complex subunit 2

0.390

DPOA2_HUMAN

DNA polymerase alpha subunit B

0.390

VPS35_HUMAN

Vacuolar protein sorting-associated protein 35

0.391

PLRG1_HUMAN

Pleiotropic regulator 1

0.391

DBR1_HUMAN

Lariat debranching enzyme

0.391

CC130_HUMAN

Coiled-coil domain-containing protein 130

0.392

TI17A_HUMAN

Mitochondrial import inner membrane translocase subunit Tim17-A

0.392

RAB7A_HUMAN

Ras-related protein Rab-7a

0.392

NAA15_HUMAN

N-alpha-acetyltransferase 15, NatA auxiliary subunit

0.392

EIF3F_HUMAN

Eukaryotic translation initiation factor 3 subunit F

0.393

CWC15_HUMAN

Spliceosome-associated protein CWC15 homolog

0.393

VPS36_HUMAN

Vacuolar protein-sorting-associated protein 36

0.393

BUD13_HUMAN

BUD13 homolog

0.393

STX16_HUMAN

Syntaxin-16

0.393

FNTB_HUMAN

Protein farnesyltransferase subunit beta

0.393

NSF1C_HUMAN

NSFL1 cofactor p47

0.393

BTF3_HUMAN

Transcription factor BTF3

0.393

TPPC3_HUMAN

Trafficking protein particle complex subunit 3

0.393

UBP14_HUMAN

Ubiquitin carboxyl-terminal hydrolase 14

0.393

FNTA_HUMAN

Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

0.393

ASTRB_HUMAN

Protein Aster-B

0.394

RPN1_HUMAN

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

0.394

MAEA_HUMAN

E3 ubiquitin-protein transferase MAEA

0.394

CTDP1_HUMAN

RNA polymerase II subunit A C-terminal domain phosphatase

0.395

TPPC8_HUMAN

Trafficking protein particle complex subunit 8

0.396

RTF2_HUMAN

Replication termination factor 2

0.396

MFRN1_HUMAN

Mitoferrin-1

0.397

CATD_HUMAN

Cathepsin D

0.397

SNR40_HUMAN

U5 small nuclear ribonucleoprotein 40 kDa protein

0.397

SF3B1_HUMAN

Splicing factor 3B subunit 1

0.398

EIF3B_HUMAN

Eukaryotic translation initiation factor 3 subunit B

0.398

CRNL1_HUMAN

Crooked neck-like protein 1

0.398

KDM5A_HUMAN

Lysine-specific demethylase 5A

0.399

PRPF3_HUMAN

U4/U6 small nuclear ribonucleoprotein Prp3

0.399

CLH1_HUMAN

Clathrin heavy chain 1

0.399

SMD3_HUMAN

Small nuclear ribonucleoprotein Sm D3

0.399

XPO2_HUMAN

Exportin-2

0.399

BYST_HUMAN

Bystin

0.399

TAM41_HUMAN

Phosphatidate cytidylyltransferase, mitochondrial

0.400

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 134 organisms (of 369)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy