RBM28_HUMAN 2019

Gene Name RBM28

Description RNA-binding protein 28

Length 759

9606

Sequence

>sp|Q9NW13|RBM28_HUMAN RNA-binding protein 28
MAGLTLFVGRLPPSARSEQLEELFSQVGPVKQCFVVTEKGSKACRGFGYVTFSMLEDVQRALKEITTFEGCKINVTVAKKKLRNKTKEKGKNENSECPKKEPKAKKAKVADKKARLIIRNLSFKCSEDDLKTVFAQFGAVLEVNIPRKPDGKMRGFGFVQFKNLLEAGKALKGMNMKEIKGRTVAVDWAVAKDKYKDTQSVSAIGEEKSHESKHQESVKKKGREEEDMEEEENDDDDDDDDEEDGVFDDEDEEEENIESKVTKPVQIQKRAVKRPAPAKSSDHSEEDSDLEESDSIDDGEELAQSDTSTEEQEDKAVQVSNKKKRKLPSDVNEGKTVFIRNLSFDSEEEELGELLQQFGELKYVRIVLHPDTEHSKGCAFAQFMTQEAAQKCLLAASPENEAGGLKLDGRQLKVDLAVTRDEAAKLQTTKVKKPTGTRNLYLAREGLIRAGTKAAEGVSAADMAKRERFELLKHQKLKDQNIFVSRTRLCLHNLPKAVDDKQLRKLLLSATSGEKGVRIKECRVMRDLKGVHGNMKGQSLGYAFAEFQEHEHALKALRLINNNPEIFGPLKRPIVEFSLEDRRKLKMKELRIQRSLQKMRSKPATGEPQKGQPEPAKDQQQKAAQHHTEEQSKVPPEQKRKAGSTSWTGFQTKAEVEQVELPDGKKRRKVLALPSHRGPKIRLRDKGKVKPVHPKKPKPQINQWKQEKQQLSSEQVSRKKAKGNKTETRFNQLVEQYKQKLLGPSKGAPLAKRSKWFDS

Domains

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Help

What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

NOL6_HUMAN

Nucleolar protein 6

0.373

STK26_HUMAN

Serine/threonine-protein kinase 26

0.375

SNAA_HUMAN

Alpha-soluble NSF attachment protein

0.376

ALG9_HUMAN

Alpha-1,2-mannosyltransferase ALG9

0.377

DIEXF_HUMAN

Digestive organ expansion factor homolog

0.377

SRP68_HUMAN

Signal recognition particle subunit SRP68

0.378

CKAP5_HUMAN

Cytoskeleton-associated protein 5

0.380

RAE1L_HUMAN

mRNA export factor

0.383

TCPQ_HUMAN

T-complex protein 1 subunit theta

0.383

SNAB_HUMAN

Beta-soluble NSF attachment protein

0.383

WDR75_HUMAN

WD repeat-containing protein 75

0.384

STX16_HUMAN

Syntaxin-16

0.385

CEBPZ_HUMAN

CCAAT/enhancer-binding protein zeta

0.386

PGTA_HUMAN

Geranylgeranyl transferase type-2 subunit alpha

0.386

STK25_HUMAN

Serine/threonine-protein kinase 25

0.387

COG4_HUMAN

Conserved oligomeric Golgi complex subunit 4

0.388

UTP20_HUMAN

Small subunit processome component 20 homolog

0.388

KRI1_HUMAN

Protein KRI1 homolog

0.389

CRNL1_HUMAN

Crooked neck-like protein 1

0.390

VPS41_HUMAN

Vacuolar protein sorting-associated protein 41 homolog

0.390

H2B1C_HUMAN

Histone H2B type 1-C/E/F/G/I

0.391

CLH1_HUMAN

Clathrin heavy chain 1

0.391

STK24_HUMAN

Serine/threonine-protein kinase 24

0.392

UTP15_HUMAN

U3 small nucleolar RNA-associated protein 15 homolog

0.392

UTP11_HUMAN

Probable U3 small nucleolar RNA-associated protein 11

0.392

BT3L4_HUMAN

Transcription factor BTF3 homolog 4

0.392

RRS1_HUMAN

Ribosome biogenesis regulatory protein homolog

0.393

IPO5_HUMAN

Importin-5

0.395

CDC73_HUMAN

Parafibromin

0.395

CNOT7_HUMAN

CCR4-NOT transcription complex subunit 7

0.395

UGGG1_HUMAN

UDP-glucose:glycoprotein glucosyltransferase 1

0.396

CPSF1_HUMAN

Cleavage and polyadenylation specificity factor subunit 1

0.396

SNF8_HUMAN

Vacuolar-sorting protein SNF8

0.396

TBL3_HUMAN

Transducin beta-like protein 3

0.397

PSA6_HUMAN

Proteasome subunit alpha type-6

0.397

CNOT8_HUMAN

CCR4-NOT transcription complex subunit 8

0.397

SF3B2_HUMAN

Splicing factor 3B subunit 2

0.397

ERGI3_HUMAN

Endoplasmic reticulum-Golgi intermediate compartment protein 3

0.397

A0A0B4J2E5_HUMAN

Uncharacterized protein

0.398

VPS35_HUMAN

Vacuolar protein sorting-associated protein 35

0.398

BOP1_HUMAN

Ribosome biogenesis protein BOP1

0.398

PSA1_HUMAN

Proteasome subunit alpha type-1

0.398

TCF25_HUMAN

Transcription factor 25

0.399

H2B2F_HUMAN

Histone H2B type 2-F

0.399

ZN622_HUMAN

Zinc finger protein 622

0.399

H2B1K_HUMAN

Histone H2B type 1-K

0.399

RAB7A_HUMAN

Ras-related protein Rab-7a

0.399

PFD3_HUMAN

Prefoldin subunit 3

0.399

H2B1D_HUMAN

Histone H2B type 1-D

0.399

TSR1_HUMAN

Pre-rRNA-processing protein TSR1 homolog

0.399

NAA15_HUMAN

N-alpha-acetyltransferase 15, NatA auxiliary subunit

0.399

SPT6H_HUMAN

Transcription elongation factor SPT6

0.399

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

NOL6_HUMAN

Nucleolar protein 6

0.373

STK26_HUMAN

Serine/threonine-protein kinase 26

0.375

SNAA_HUMAN

Alpha-soluble NSF attachment protein

0.376

ALG9_HUMAN

Alpha-1,2-mannosyltransferase ALG9

0.377

DIEXF_HUMAN

Digestive organ expansion factor homolog

0.377

SRP68_HUMAN

Signal recognition particle subunit SRP68

0.378

CKAP5_HUMAN

Cytoskeleton-associated protein 5

0.380

RAE1L_HUMAN

mRNA export factor

0.383

TCPQ_HUMAN

T-complex protein 1 subunit theta

0.383

SNAB_HUMAN

Beta-soluble NSF attachment protein

0.383

WDR75_HUMAN

WD repeat-containing protein 75

0.384

STX16_HUMAN

Syntaxin-16

0.385

CEBPZ_HUMAN

CCAAT/enhancer-binding protein zeta

0.386

PGTA_HUMAN

Geranylgeranyl transferase type-2 subunit alpha

0.386

STK25_HUMAN

Serine/threonine-protein kinase 25

0.387

COG4_HUMAN

Conserved oligomeric Golgi complex subunit 4

0.388

UTP20_HUMAN

Small subunit processome component 20 homolog

0.388

KRI1_HUMAN

Protein KRI1 homolog

0.389

CRNL1_HUMAN

Crooked neck-like protein 1

0.390

VPS41_HUMAN

Vacuolar protein sorting-associated protein 41 homolog

0.390

H2B1C_HUMAN

Histone H2B type 1-C/E/F/G/I

0.391

CLH1_HUMAN

Clathrin heavy chain 1

0.391

STK24_HUMAN

Serine/threonine-protein kinase 24

0.392

UTP15_HUMAN

U3 small nucleolar RNA-associated protein 15 homolog

0.392

UTP11_HUMAN

Probable U3 small nucleolar RNA-associated protein 11

0.392

BT3L4_HUMAN

Transcription factor BTF3 homolog 4

0.392

RRS1_HUMAN

Ribosome biogenesis regulatory protein homolog

0.393

IPO5_HUMAN

Importin-5

0.395

CDC73_HUMAN

Parafibromin

0.395

CNOT7_HUMAN

CCR4-NOT transcription complex subunit 7

0.395

UGGG1_HUMAN

UDP-glucose:glycoprotein glucosyltransferase 1

0.396

CPSF1_HUMAN

Cleavage and polyadenylation specificity factor subunit 1

0.396

SNF8_HUMAN

Vacuolar-sorting protein SNF8

0.396

TBL3_HUMAN

Transducin beta-like protein 3

0.397

PSA6_HUMAN

Proteasome subunit alpha type-6

0.397

CNOT8_HUMAN

CCR4-NOT transcription complex subunit 8

0.397

SF3B2_HUMAN

Splicing factor 3B subunit 2

0.397

ERGI3_HUMAN

Endoplasmic reticulum-Golgi intermediate compartment protein 3

0.397

A0A0B4J2E5_HUMAN

Uncharacterized protein

0.398

VPS35_HUMAN

Vacuolar protein sorting-associated protein 35

0.398

BOP1_HUMAN

Ribosome biogenesis protein BOP1

0.398

PSA1_HUMAN

Proteasome subunit alpha type-1

0.398

TCF25_HUMAN

Transcription factor 25

0.399

H2B2F_HUMAN

Histone H2B type 2-F

0.399

ZN622_HUMAN

Zinc finger protein 622

0.399

H2B1K_HUMAN

Histone H2B type 1-K

0.399

RAB7A_HUMAN

Ras-related protein Rab-7a

0.399

PFD3_HUMAN

Prefoldin subunit 3

0.399

H2B1D_HUMAN

Histone H2B type 1-D

0.399

TSR1_HUMAN

Pre-rRNA-processing protein TSR1 homolog

0.399

NAA15_HUMAN

N-alpha-acetyltransferase 15, NatA auxiliary subunit

0.399

SPT6H_HUMAN

Transcription elongation factor SPT6

0.399

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 135 organisms (of 369)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy