TMM19_HUMAN 2019

Gene Name TMM19

Description Transmembrane protein 19

Length 336

9606

Sequence

>sp|Q96HH6|TMM19_HUMAN Transmembrane protein 19
MTDLNDNICKRYIKMITNIVILSLIICISLAFWIISMTASTYYGNLRPISPWRWLFSVVVPVLIVSNGLKKKSLDHSGALGGLVVGFILTIANFSFFTSLLMFFLSSSKLTKWKGEVKKRLDSEYKEGGQRNWVQVFCNGAVPTELALLYMIENGPGEIPVDFSKQYSASWMCLSLLAALACSAGDTWASEVGPVLSKSSPRLITTWEKVPVGTNGGVTVVGLVSSLLGGTFVGIAYFLTQLIFVNDLDISAPQWPIIAFGGLAGLLGSIVDSYLGATMQYTGLDESTGMVVNSPTNKARHIAGKPILDNNAVNLFSSVLIALLLPTAAWGFWPRG

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

No protein with similar profile across the domains were found

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

ECD_HUMAN

Protein ecdysoneless homolog

0.333

CSN7B_HUMAN

COP9 signalosome complex subunit 7b

0.351

CSN7A_HUMAN

COP9 signalosome complex subunit 7a

0.353

CSN4_HUMAN

COP9 signalosome complex subunit 4

0.355

STRAP_HUMAN

Serine-threonine kinase receptor-associated protein

0.355

CSN1_HUMAN

COP9 signalosome complex subunit 1

0.356

ACLY_HUMAN

ATP-citrate synthase

0.362

GCDH_HUMAN

Glutaryl-CoA dehydrogenase, mitochondrial

0.364

MCCB_HUMAN

Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

0.371

MMSA_HUMAN

Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial

0.374

CSN3_HUMAN

COP9 signalosome complex subunit 3

0.377

ACSF2_HUMAN

Acyl-CoA synthetase family member 2, mitochondrial

0.377

UVRAG_HUMAN

UV radiation resistance-associated gene protein

0.379

MOCOS_HUMAN

Molybdenum cofactor sulfurase

0.379

S45A2_HUMAN

Membrane-associated transporter protein

0.379

EIF3D_HUMAN

Eukaryotic translation initiation factor 3 subunit D

0.380

IVD_HUMAN

Isovaleryl-CoA dehydrogenase, mitochondrial

0.381

EIF3E_HUMAN

Eukaryotic translation initiation factor 3 subunit E

0.381

RBM39_HUMAN

RNA-binding protein 39

0.383

MOCS1_HUMAN

Molybdenum cofactor biosynthesis protein 1

0.383

IPO11_HUMAN

Importin-11

0.384

CLPT1_HUMAN

Cleft lip and palate transmembrane protein 1

0.385

EIF3F_HUMAN

Eukaryotic translation initiation factor 3 subunit F

0.385

PIMT_HUMAN

Protein-L-isoaspartate(D-aspartate) O-methyltransferase

0.386

GEPH_HUMAN

Gephyrin

0.387

PUR2_HUMAN

Trifunctional purine biosynthetic protein adenosine-3

0.388

GPTC1_HUMAN

G patch domain-containing protein 1

0.389

CAND1_HUMAN

Cullin-associated NEDD8-dissociated protein 1

0.389

NADK_HUMAN

NAD kinase

0.390

ODBB_HUMAN

2-oxoisovalerate dehydrogenase subunit beta, mitochondrial

0.390

CHDH_HUMAN

Choline dehydrogenase, mitochondrial

0.391

ODBA_HUMAN

2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial

0.391

CCD12_HUMAN

Coiled-coil domain-containing protein 12

0.392

INO1_HUMAN

Inositol-3-phosphate synthase 1

0.392

EIF3L_HUMAN

Eukaryotic translation initiation factor 3 subunit L

0.392

PUR1_HUMAN

Amidophosphoribosyltransferase

0.393

HMGCL_HUMAN

Hydroxymethylglutaryl-CoA lyase, mitochondrial

0.393

3HIDH_HUMAN

3-hydroxyisobutyrate dehydrogenase, mitochondrial

0.393

CTBL1_HUMAN

Beta-catenin-like protein 1

0.393

KDM8_HUMAN

Bifunctional peptidase and arginyl-hydroxylase JMJD5

0.394

THOC1_HUMAN

THO complex subunit 1

0.394

VTA1_HUMAN

Vacuolar protein sorting-associated protein VTA1 homolog

0.394

RBM8A_HUMAN

RNA-binding protein 8A

0.395

U5S1_HUMAN

116 kDa U5 small nuclear ribonucleoprotein component

0.395

GALM_HUMAN

Aldose 1-epimerase

0.395

HEM6_HUMAN

Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial

0.395

DCUP_HUMAN

Uroporphyrinogen decarboxylase

0.395

TPC10_HUMAN

Trafficking protein particle complex subunit 10

0.395

PHYD1_HUMAN

Phytanoyl-CoA dioxygenase domain-containing protein 1

0.395

PUR9_HUMAN

Bifunctional purine biosynthesis protein PURH

0.396

HAOX1_HUMAN

Hydroxyacid oxidase 1

0.396

EIF3M_HUMAN

Eukaryotic translation initiation factor 3 subunit M

0.397

PPOX_HUMAN

Protoporphyrinogen oxidase

0.397

NDUF6_HUMAN

NADH dehydrogenase (ubiquinone) complex I, assembly factor 6

0.398

RIC1_HUMAN

RAB6A-GEF complex partner protein 1

0.398

HMGC2_HUMAN

3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic

0.398

PPWD1_HUMAN

Peptidylprolyl isomerase domain and WD repeat-containing protein 1

0.398

SYF2_HUMAN

Pre-mRNA-splicing factor SYF2

0.398

EMC2_HUMAN

ER membrane protein complex subunit 2

0.399

NDUV1_HUMAN

NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

0.399

SND1_HUMAN

Staphylococcal nuclease domain-containing protein 1

0.399

PPT1_HUMAN

Palmitoyl-protein thioesterase 1

0.399

DNJC3_HUMAN

DnaJ homolog subfamily C member 3

0.399

NDUA9_HUMAN

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial

0.399

EIF3K_HUMAN

Eukaryotic translation initiation factor 3 subunit K

0.400

ARLY_HUMAN

Argininosuccinate lyase

0.400

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 121 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy