IDLC_HUMAN 2019

Gene Name IDLC

Description Axonemal dynein light intermediate polypeptide 1

Length 258

9606

Sequence

>sp|O14645|IDLC_HUMAN Axonemal dynein light intermediate polypeptide 1
MIPPADSLLKYDTPVLVSRNTEKRSPKARLLKVSPQQPGPSGSAPQPPKTKLPSTPCVPDPTKQAEEILNAILPPREWVEDTQLWIQQVSSTPSTRMDVVHLQEQLDLKLQQRQARETGICPVRRELYSQCFDELIREVTINCAERGLLLLRVRDEIRMTIAAYQTLYESSVAFGMRKALQAEQGKSDMERKIAELETEKRDLERQVNEQKAKCEATEKRESERRQVEEKKHNEEIQFLKRTNQQLKAQLEGIIAPKK

Domains

Loading...

Help

What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

CF206_HUMAN

Cilia- and flagella-associated protein 206

0.195

IF122_HUMAN

Intraflagellar transport protein 122 homolog

0.245

DRC4_HUMAN

Dynein regulatory complex subunit 4

0.245

IFT56_HUMAN

Intraflagellar transport protein 56

0.245

CFA52_HUMAN

Cilia- and flagella-associated protein 52

0.248

CB5D1_HUMAN

Cytochrome b5 domain-containing protein 1

0.252

RSH4A_HUMAN

Radial spoke head protein 4 homolog A

0.252

WDR35_HUMAN

WD repeat-containing protein 35

0.269

IF172_HUMAN

Intraflagellar transport protein 172 homolog

0.269

CFA43_HUMAN

Cilia- and flagella-associated protein 43

0.276

PACRG_HUMAN

Parkin coregulated gene protein

0.289

IFT80_HUMAN

Intraflagellar transport protein 80 homolog

0.290

CFA57_HUMAN

Cilia- and flagella-associated protein 57

0.292

IQUB_HUMAN

IQ and ubiquitin-like domain-containing protein

0.292

WDR63_HUMAN

WD repeat-containing protein 63

0.294

RSPH9_HUMAN

Radial spoke head protein 9 homolog

0.296

IFT46_HUMAN

Intraflagellar transport protein 46 homolog

0.305

WDR19_HUMAN

WD repeat-containing protein 19

0.307

IFT57_HUMAN

Intraflagellar transport protein 57 homolog

0.307

IF140_HUMAN

Intraflagellar transport protein 140 homolog

0.309

DRC11_HUMAN

Dynein regulatory complex protein 11

0.312

SPAG6_HUMAN

Sperm-associated antigen 6

0.312

DRC7_HUMAN

Dynein regulatory complex subunit 7

0.312

HYDIN_HUMAN

Hydrocephalus-inducing protein homolog

0.314

CCD39_HUMAN

Coiled-coil domain-containing protein 39

0.314

DRC1_HUMAN

Dynein regulatory complex protein 1

0.316

RSPH3_HUMAN

Radial spoke head protein 3 homolog

0.318

CC113_HUMAN

Coiled-coil domain-containing protein 113

0.318

TT30B_HUMAN

Tetratricopeptide repeat protein 30B

0.322

TILB_HUMAN

Protein tilB homolog

0.325

EFHC1_HUMAN

EF-hand domain-containing protein 1

0.325

DNAL1_HUMAN

Dynein light chain 1, axonemal

0.331

CCD40_HUMAN

Coiled-coil domain-containing protein 40

0.335

IFT52_HUMAN

Intraflagellar transport protein 52 homolog

0.337

RSH6A_HUMAN

Radial spoke head protein 6 homolog A

0.338

TT30A_HUMAN

Tetratricopeptide repeat protein 30A

0.339

ZMY10_HUMAN

Zinc finger MYND domain-containing protein 10

0.341

MIPT3_HUMAN

TRAF3-interacting protein 1

0.341

DAAF5_HUMAN

Dynein assembly factor 5, axonemal

0.345

ENKUR_HUMAN

Enkurin

0.349

CFA44_HUMAN

Cilia- and flagella-associated protein 44

0.354

CF251_HUMAN

Cilia- and flagella-associated protein 251

0.354

CLUA1_HUMAN

Clusterin-associated protein 1

0.356

TT21B_HUMAN

Tetratricopeptide repeat protein 21B

0.360

CFA58_HUMAN

Cilia- and flagella-associated protein 58

0.366

DRC5_HUMAN

Dynein regulatory complex subunit 5

0.371

CFA91_HUMAN

Cilia- and flagella-associated protein 91

0.371

CFA61_HUMAN

Cilia- and flagella-associated protein 61

0.373

KIFA3_HUMAN

Kinesin-associated protein 3

0.376

CFA45_HUMAN

Cilia- and flagella-associated protein 45

0.383

DRC3_HUMAN

Dynein regulatory complex subunit 3

0.384

CCD42_HUMAN

Coiled-coil domain-containing protein 42

0.385

CFA65_HUMAN

Cilia- and flagella-associated protein 65

0.385

CASC1_HUMAN

Protein CASC1

0.390

DNAI2_HUMAN

Dynein intermediate chain 2, axonemal

0.391

SSNA1_HUMAN

Sjoegren syndrome nuclear autoantigen 1

0.393

IFT81_HUMAN

Intraflagellar transport protein 81 homolog

0.396

CCD63_HUMAN

Coiled-coil domain-containing protein 63

0.398

DYH7_HUMAN

Dynein heavy chain 7, axonemal

0.398

CE104_HUMAN

Centrosomal protein of 104 kDa

0.399

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

CF206_HUMAN

Cilia- and flagella-associated protein 206

0.285

IQUB_HUMAN

IQ and ubiquitin-like domain-containing protein

0.309

RSH4A_HUMAN

Radial spoke head protein 4 homolog A

0.316

IF172_HUMAN

Intraflagellar transport protein 172 homolog

0.317

CFA43_HUMAN

Cilia- and flagella-associated protein 43

0.318

IFT46_HUMAN

Intraflagellar transport protein 46 homolog

0.323

IF122_HUMAN

Intraflagellar transport protein 122 homolog

0.323

DRC7_HUMAN

Dynein regulatory complex subunit 7

0.326

IFT80_HUMAN

Intraflagellar transport protein 80 homolog

0.328

IFT56_HUMAN

Intraflagellar transport protein 56

0.328

PACRG_HUMAN

Parkin coregulated gene protein

0.329

WDR35_HUMAN

WD repeat-containing protein 35

0.329

CFA57_HUMAN

Cilia- and flagella-associated protein 57

0.329

CFA44_HUMAN

Cilia- and flagella-associated protein 44

0.336

IF140_HUMAN

Intraflagellar transport protein 140 homolog

0.339

DRC4_HUMAN

Dynein regulatory complex subunit 4

0.342

WDR19_HUMAN

WD repeat-containing protein 19

0.342

IFT57_HUMAN

Intraflagellar transport protein 57 homolog

0.343

RSPH9_HUMAN

Radial spoke head protein 9 homolog

0.346

RSPH3_HUMAN

Radial spoke head protein 3 homolog

0.348

CFA45_HUMAN

Cilia- and flagella-associated protein 45

0.350

DRC11_HUMAN

Dynein regulatory complex protein 11

0.355

CFA52_HUMAN

Cilia- and flagella-associated protein 52

0.355

IFT52_HUMAN

Intraflagellar transport protein 52 homolog

0.357

DRC1_HUMAN

Dynein regulatory complex protein 1

0.357

MIPT3_HUMAN

TRAF3-interacting protein 1

0.359

CLUA1_HUMAN

Clusterin-associated protein 1

0.361

WDR63_HUMAN

WD repeat-containing protein 63

0.362

CASC1_HUMAN

Protein CASC1

0.366

CCD39_HUMAN

Coiled-coil domain-containing protein 39

0.366

CFA91_HUMAN

Cilia- and flagella-associated protein 91

0.368

DAAF5_HUMAN

Dynein assembly factor 5, axonemal

0.371

PIHD3_HUMAN

Protein PIH1D3

0.371

DNAI2_HUMAN

Dynein intermediate chain 2, axonemal

0.372

DRC5_HUMAN

Dynein regulatory complex subunit 5

0.373

IFT88_HUMAN

Intraflagellar transport protein 88 homolog

0.374

DNAL4_HUMAN

Dynein light chain 4, axonemal

0.377

DC2L1_HUMAN

Cytoplasmic dynein 2 light intermediate chain 1

0.377

KIFA3_HUMAN

Kinesin-associated protein 3

0.379

TT21B_HUMAN

Tetratricopeptide repeat protein 21B

0.381

CFA61_HUMAN

Cilia- and flagella-associated protein 61

0.382

ENKUR_HUMAN

Enkurin

0.386

TT30B_HUMAN

Tetratricopeptide repeat protein 30B

0.386

TBC19_HUMAN

TBC1 domain family member 19

0.386

IFT20_HUMAN

Intraflagellar transport protein 20 homolog

0.386

DNAI1_HUMAN

Dynein intermediate chain 1, axonemal

0.387

CFA58_HUMAN

Cilia- and flagella-associated protein 58

0.388

DRC2_HUMAN

Dynein regulatory complex subunit 2

0.390

C2D2A_HUMAN

Coiled-coil and C2 domain-containing protein 2A

0.390

TT30A_HUMAN

Tetratricopeptide repeat protein 30A

0.391

EFHC2_HUMAN

EF-hand domain-containing family member C2

0.392

POC1A_HUMAN

POC1 centriolar protein homolog A

0.392

TILB_HUMAN

Protein tilB homolog

0.394

EFHC1_HUMAN

EF-hand domain-containing protein 1

0.397

CENPJ_HUMAN

Centromere protein J

0.398

RIBC2_HUMAN

RIB43A-like with coiled-coils protein 2

0.398

CP131_HUMAN

Centrosomal protein of 131 kDa

0.400

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 79 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy