MPIP3_HUMAN 2019

Gene Name MPIP3

Description M-phase inducer phosphatase 3

Length 473

9606

Sequence

>sp|P30307|MPIP3_HUMAN M-phase inducer phosphatase 3
MSTELFSSTREEGSSGSGPSFRSNQRKMLNLLLERDTSFTVCPDVPRTPVGKFLGDSANLSILSGGTPKRCLDLSNLSSGEITATQLTTSADLDETGHLDSSGLQEVHLAGMNHDQHLMKCSPAQLLCSTPNGLDRGHRKRDAMCSSSANKENDNGNLVDSEMKYLGSPITTVPKLDKNPNLGEDQAEEISDELMEFSLKDQEAKVSRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDKVKKKYFSGQGKLRKGLCLKKTVSLCDITITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQDLKYVNPETVAALLSGKFQGLIEKFYVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKKPIVPLDTQKRIIIVFHCEFSSERGPRMCRCLREEDRSLNQYPALYYPELYILKGGYRDFFPEYMELCEPQSYCPMHHQDHKTELLRCRSQSKVQEGERQLREQIALLVKDMSP

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

MPIP2_HUMAN

M-phase inducer phosphatase 2

0.265

MPIP1_HUMAN

M-phase inducer phosphatase 1

0.280

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

MPIP2_HUMAN

M-phase inducer phosphatase 2

0.163

MPIP1_HUMAN

M-phase inducer phosphatase 1

0.219

CC14B_HUMAN

Dual specificity protein phosphatase CDC14B

0.354

AT134_HUMAN

Probable cation-transporting ATPase 13A4

0.361

ACON_HUMAN

Aconitate hydratase, mitochondrial

0.363

CC14A_HUMAN

Dual specificity protein phosphatase CDC14A

0.364

RRAGB_HUMAN

Ras-related GTP-binding protein B

0.364

FBXW7_HUMAN

F-box/WD repeat-containing protein 7

0.366

AT133_HUMAN

Probable cation-transporting ATPase 13A3

0.367

SYNC_HUMAN

Asparagine--tRNA ligase, cytoplasmic

0.369

PP2BB_HUMAN

Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform

0.373

PAK1_HUMAN

Serine/threonine-protein kinase PAK 1

0.374

PGPS1_HUMAN

CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial

0.376

RCC1_HUMAN

Regulator of chromosome condensation

0.376

ACATN_HUMAN

Acetyl-coenzyme A transporter 1

0.376

PAK2_HUMAN

Serine/threonine-protein kinase PAK 2

0.376

SOS1_HUMAN

Son of sevenless homolog 1

0.376

SEPT7_HUMAN

Septin-7

0.376

AT135_HUMAN

Probable cation-transporting ATPase 13A5

0.377

CBPA3_HUMAN

Mast cell carboxypeptidase A

0.379

STRP2_HUMAN

Striatin-interacting protein 2

0.381

RHOA_HUMAN

Transforming protein RhoA

0.381

RRAGD_HUMAN

Ras-related GTP-binding protein D

0.381

GSH1_HUMAN

Glutamate--cysteine ligase catalytic subunit

0.381

DEPD5_HUMAN

GATOR complex protein DEPDC5

0.382

PP2BC_HUMAN

Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform

0.382

PLPL6_HUMAN

Neuropathy target esterase

0.382

VIGLN_HUMAN

Vigilin

0.382

PAK3_HUMAN

Serine/threonine-protein kinase PAK 3

0.383

PP2BA_HUMAN

Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform

0.385

DCPS_HUMAN

m7GpppX diphosphatase

0.385

NPRL2_HUMAN

GATOR complex protein NPRL2

0.386

SOS2_HUMAN

Son of sevenless homolog 2

0.387

STRP1_HUMAN

Striatin-interacting protein 1

0.387

GOLP3_HUMAN

Golgi phosphoprotein 3

0.388

AL4A1_HUMAN

Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial

0.389

RAGP1_HUMAN

Ran GTPase-activating protein 1

0.389

SYYC_HUMAN

Tyrosine--tRNA ligase, cytoplasmic

0.389

RHOC_HUMAN

Rho-related GTP-binding protein RhoC

0.389

DYHC1_HUMAN

Cytoplasmic dynein 1 heavy chain 1

0.389

IQGA3_HUMAN

Ras GTPase-activating-like protein IQGAP3

0.389

SYRM_HUMAN

Probable arginine--tRNA ligase, mitochondrial

0.390

CBPA5_HUMAN

Carboxypeptidase A5

0.390

RRAGA_HUMAN

Ras-related GTP-binding protein A

0.390

CLCN5_HUMAN

H(+)/Cl(-) exchange transporter 5

0.391

GYS1_HUMAN

Glycogen [starch] synthase, muscle

0.391

SYCC_HUMAN

Cysteine--tRNA ligase, cytoplasmic

0.392

CBPA4_HUMAN

Carboxypeptidase A4

0.392

GYS2_HUMAN

Glycogen [starch] synthase, liver

0.392

COR1A_HUMAN

Coronin-1A

0.392

AT2C1_HUMAN

Calcium-transporting ATPase type 2C member 1

0.392

RICTR_HUMAN

Rapamycin-insensitive companion of mTOR

0.392

H33_HUMAN

Histone H3.3

0.393

RMND1_HUMAN

Required for meiotic nuclear division protein 1 homolog

0.393

AVL9_HUMAN

Late secretory pathway protein AVL9 homolog

0.393

SRF_HUMAN

Serum response factor

0.393

CBPB1_HUMAN

Carboxypeptidase B

0.394

PLPL7_HUMAN

Patatin-like phospholipase domain-containing protein 7

0.394

PAN3_HUMAN

PAN2-PAN3 deadenylation complex subunit PAN3

0.396

DPP10_HUMAN

Inactive dipeptidyl peptidase 10

0.396

CUL1_HUMAN

Cullin-1

0.396

CLCN3_HUMAN

H(+)/Cl(-) exchange transporter 3

0.397

GATA4_HUMAN

Transcription factor GATA-4

0.397

CLCN4_HUMAN

H(+)/Cl(-) exchange transporter 4

0.397

DPP4_HUMAN

Dipeptidyl peptidase 4

0.397

LIS1_HUMAN

Platelet-activating factor acetylhydrolase IB subunit alpha

0.397

RRAGC_HUMAN

Ras-related GTP-binding protein C

0.398

COR1B_HUMAN

Coronin-1B

0.398

DOT1L_HUMAN

Histone-lysine N-methyltransferase, H3 lysine-79 specific

0.398

CCHL_HUMAN

Cytochrome c-type heme lyase

0.398

CMC2_HUMAN

Calcium-binding mitochondrial carrier protein Aralar2

0.399

PLK1_HUMAN

Serine/threonine-protein kinase PLK1

0.399

S2536_HUMAN

Solute carrier family 25 member 36

0.399

ATP9A_HUMAN

Probable phospholipid-transporting ATPase IIA

0.400

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 108 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy