KC1G2_HUMAN 2019

Gene Name KC1G2

Description Casein kinase I isoform gamma-2

Length 415

9606

Sequence

>sp|P78368|KC1G2_HUMAN Casein kinase I isoform gamma-2
MDFDKKGGKGETEEGRRMSKAGGGRSSHGIRSSGTSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATEGVPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTKRQHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRSGFVFDYEYDWAGKPLPTPIGTVHTDLPSQPQLRDKTQPHSKNQALNSTNGELNADDPTAGHSNAPITAPAEVEVADETKCCCFFKRRKRKSLQRHK

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

KC1G1_HUMAN

Casein kinase I isoform gamma-1

0.316

DPOG1_HUMAN

DNA polymerase subunit gamma-1

0.393

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

GOLP3_HUMAN

Golgi phosphoprotein 3

0.313

RHOA_HUMAN

Transforming protein RhoA

0.324

SEPT7_HUMAN

Septin-7

0.334

SLMAP_HUMAN

Sarcolemmal membrane-associated protein

0.337

RHOC_HUMAN

Rho-related GTP-binding protein RhoC

0.337

DPOG1_HUMAN

DNA polymerase subunit gamma-1

0.337

COX5A_HUMAN

Cytochrome c oxidase subunit 5A, mitochondrial

0.338

SYRM_HUMAN

Probable arginine--tRNA ligase, mitochondrial

0.338

SURF4_HUMAN

Surfeit locus protein 4

0.340

CLCN3_HUMAN

H(+)/Cl(-) exchange transporter 3

0.340

CLCN4_HUMAN

H(+)/Cl(-) exchange transporter 4

0.340

KC1G1_HUMAN

Casein kinase I isoform gamma-1

0.341

SYNC_HUMAN

Asparagine--tRNA ligase, cytoplasmic

0.344

RAGP1_HUMAN

Ran GTPase-activating protein 1

0.345

CLCN5_HUMAN

H(+)/Cl(-) exchange transporter 5

0.347

VIGLN_HUMAN

Vigilin

0.348

SRF_HUMAN

Serum response factor

0.350

PAK2_HUMAN

Serine/threonine-protein kinase PAK 2

0.351

PAK1_HUMAN

Serine/threonine-protein kinase PAK 1

0.352

GYS2_HUMAN

Glycogen [starch] synthase, liver

0.355

PAK3_HUMAN

Serine/threonine-protein kinase PAK 3

0.355

DPP10_HUMAN

Inactive dipeptidyl peptidase 10

0.357

FBXW7_HUMAN

F-box/WD repeat-containing protein 7

0.357

DPP4_HUMAN

Dipeptidyl peptidase 4

0.358

GATA4_HUMAN

Transcription factor GATA-4

0.361

CUL1_HUMAN

Cullin-1

0.361

GATA2_HUMAN

Endothelial transcription factor GATA-2

0.362

SEPR_HUMAN

Prolyl endopeptidase FAP

0.362

HIP1R_HUMAN

Huntingtin-interacting protein 1-related protein

0.363

GYS1_HUMAN

Glycogen [starch] synthase, muscle

0.364

KC1G3_HUMAN

Casein kinase I isoform gamma-3

0.364

PBDC1_HUMAN

Protein PBDC1

0.367

S39A9_HUMAN

Zinc transporter ZIP9

0.367

HIP1_HUMAN

Huntingtin-interacting protein 1

0.368

AL4A1_HUMAN

Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial

0.368

ZNT1_HUMAN

Zinc transporter 1

0.371

PB1_HUMAN

Protein polybromo-1

0.372

PLPL6_HUMAN

Neuropathy target esterase

0.374

ATP9A_HUMAN

Probable phospholipid-transporting ATPase IIA

0.374

TOM70_HUMAN

Mitochondrial import receptor subunit TOM70

0.375

POMT2_HUMAN

Protein O-mannosyl-transferase 2

0.376

RCC1_HUMAN

Regulator of chromosome condensation

0.377

DYR_HUMAN

Dihydrofolate reductase

0.377

SOS1_HUMAN

Son of sevenless homolog 1

0.377

GATA6_HUMAN

Transcription factor GATA-6

0.377

GATA3_HUMAN

Trans-acting T-cell-specific transcription factor GATA-3

0.377

IQGA1_HUMAN

Ras GTPase-activating-like protein IQGAP1

0.378

DOT1L_HUMAN

Histone-lysine N-methyltransferase, H3 lysine-79 specific

0.378

UB2G2_HUMAN

Ubiquitin-conjugating enzyme E2 G2

0.379

GDE_HUMAN

Glycogen debranching enzyme

0.379

TRM44_HUMAN

Probable tRNA (uracil-O(2)-)-methyltransferase

0.379

SNX12_HUMAN

Sorting nexin-12

0.380

AVL9_HUMAN

Late secretory pathway protein AVL9 homolog

0.382

AT133_HUMAN

Probable cation-transporting ATPase 13A3

0.383

DPP6_HUMAN

Dipeptidyl aminopeptidase-like protein 6

0.385

ATP9B_HUMAN

Probable phospholipid-transporting ATPase IIB

0.385

SOS2_HUMAN

Son of sevenless homolog 2

0.385

OGFD1_HUMAN

Prolyl 3-hydroxylase OGFOD1

0.386

TM9S2_HUMAN

Transmembrane 9 superfamily member 2

0.386

CACP_HUMAN

Carnitine O-acetyltransferase

0.387

ERGI2_HUMAN

Endoplasmic reticulum-Golgi intermediate compartment protein 2

0.387

CEGT_HUMAN

Ceramide glucosyltransferase

0.387

DCPS_HUMAN

m7GpppX diphosphatase

0.389

YLAT2_HUMAN

Y+L amino acid transporter 2

0.389

PLPL7_HUMAN

Patatin-like phospholipase domain-containing protein 7

0.390

DOP1_HUMAN

Protein dopey-1

0.390

RFX2_HUMAN

DNA-binding protein RFX2

0.391

SNX3_HUMAN

Sorting nexin-3

0.391

H33_HUMAN

Histone H3.3

0.391

ACON_HUMAN

Aconitate hydratase, mitochondrial

0.391

DEPD5_HUMAN

GATOR complex protein DEPDC5

0.392

PP2BA_HUMAN

Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform

0.392

DOCK5_HUMAN

Dedicator of cytokinesis protein 5

0.392

STRP1_HUMAN

Striatin-interacting protein 1

0.392

RFX3_HUMAN

Transcription factor RFX3

0.392

AT2C1_HUMAN

Calcium-transporting ATPase type 2C member 1

0.393

DOP2_HUMAN

Protein dopey-2

0.394

S2536_HUMAN

Solute carrier family 25 member 36

0.395

GATA5_HUMAN

Transcription factor GATA-5

0.396

NPRL2_HUMAN

GATOR complex protein NPRL2

0.396

IQGA3_HUMAN

Ras GTPase-activating-like protein IQGAP3

0.396

DOCK3_HUMAN

Dedicator of cytokinesis protein 3

0.397

M3K4_HUMAN

Mitogen-activated protein kinase kinase kinase 4

0.398

GSH1_HUMAN

Glutamate--cysteine ligase catalytic subunit

0.400

HYAS3_HUMAN

Hyaluronan synthase 3

0.400

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 86 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy