QPCTL_HUMAN 2019

Gene Name QPCTL

Description Glutaminyl-peptide cyclotransferase-like protein

Length 382

9606

Sequence

>sp|Q9NXS2|QPCTL_HUMAN Glutaminyl-peptide cyclotransferase-like protein
MRSGGRGRPRLRLGERGLMEPLLPPKRRLLPRVRLLPLLLALAVGSAFYTIWSGWHRRTEELPLGRELRVPLIGSLPEARLRRVVGQLDPQRLWSTYLRPLLVVRTPGSPGNLQVRKFLEATLRSLTAGWHVELDPFTASTPLGPVDFGNVVATLDPRAARHLTLACHYDSKLFPPGSTPFVGATDSAVPCALLLELAQALDLELSRAKKQAAPVTLQLLFLDGEEALKEWGPKDSLYGSRHLAQLMESIPHSPGPTRIQAIELFMLLDLLGAPNPTFYSHFPRTVRWFHRLRSIEKRLHRLNLLQSHPQEVMYFQPGEPFGSVEDDHIPFLRRGVPVLHLISTPFPAVWHTPADTEVNLHPPTVHNLCRILAVFLAEYLGL

Domains

Loading...

Help

What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

QPCT_HUMAN

Glutaminyl-peptide cyclotransferase

0.357

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

QPCT_HUMAN

Glutaminyl-peptide cyclotransferase

0.197

GYS1_HUMAN

Glycogen [starch] synthase, muscle

0.333

AL4A1_HUMAN

Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial

0.335

CLCN3_HUMAN

H(+)/Cl(-) exchange transporter 3

0.338

PAK2_HUMAN

Serine/threonine-protein kinase PAK 2

0.338

CLCN5_HUMAN

H(+)/Cl(-) exchange transporter 5

0.341

CLCN4_HUMAN

H(+)/Cl(-) exchange transporter 4

0.341

PAK1_HUMAN

Serine/threonine-protein kinase PAK 1

0.346

PAK3_HUMAN

Serine/threonine-protein kinase PAK 3

0.346

GYS2_HUMAN

Glycogen [starch] synthase, liver

0.353

GOLP3_HUMAN

Golgi phosphoprotein 3

0.358

SLMAP_HUMAN

Sarcolemmal membrane-associated protein

0.359

VIGLN_HUMAN

Vigilin

0.362

COX5A_HUMAN

Cytochrome c oxidase subunit 5A, mitochondrial

0.364

SYNC_HUMAN

Asparagine--tRNA ligase, cytoplasmic

0.365

KMT5C_HUMAN

Histone-lysine N-methyltransferase KMT5C

0.366

DPP4_HUMAN

Dipeptidyl peptidase 4

0.369

SOS1_HUMAN

Son of sevenless homolog 1

0.369

SEPR_HUMAN

Prolyl endopeptidase FAP

0.370

KMT5B_HUMAN

Histone-lysine N-methyltransferase KMT5B

0.370

DPP10_HUMAN

Inactive dipeptidyl peptidase 10

0.371

CUL1_HUMAN

Cullin-1

0.372

DOCK1_HUMAN

Dedicator of cytokinesis protein 1

0.372

DOCK2_HUMAN

Dedicator of cytokinesis protein 2

0.372

RRAGB_HUMAN

Ras-related GTP-binding protein B

0.372

SOS2_HUMAN

Son of sevenless homolog 2

0.374

DBNL_HUMAN

Drebrin-like protein

0.375

SURF4_HUMAN

Surfeit locus protein 4

0.375

DPOG1_HUMAN

DNA polymerase subunit gamma-1

0.376

DOCK5_HUMAN

Dedicator of cytokinesis protein 5

0.377

SRF_HUMAN

Serum response factor

0.377

HIP1_HUMAN

Huntingtin-interacting protein 1

0.378

ZNT1_HUMAN

Zinc transporter 1

0.379

COR1A_HUMAN

Coronin-1A

0.379

GDE_HUMAN

Glycogen debranching enzyme

0.380

HIP1R_HUMAN

Huntingtin-interacting protein 1-related protein

0.380

STRP1_HUMAN

Striatin-interacting protein 1

0.381

COR1B_HUMAN

Coronin-1B

0.382

SYRM_HUMAN

Probable arginine--tRNA ligase, mitochondrial

0.383

STRP2_HUMAN

Striatin-interacting protein 2

0.383

PP2BA_HUMAN

Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform

0.384

DEPD5_HUMAN

GATOR complex protein DEPDC5

0.384

CORO6_HUMAN

Coronin-6

0.384

DOT1L_HUMAN

Histone-lysine N-methyltransferase, H3 lysine-79 specific

0.386

TM9S2_HUMAN

Transmembrane 9 superfamily member 2

0.387

PP2BB_HUMAN

Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform

0.387

ACES_HUMAN

Acetylcholinesterase

0.387

S39A9_HUMAN

Zinc transporter ZIP9

0.388

DOCK3_HUMAN

Dedicator of cytokinesis protein 3

0.389

PP2BC_HUMAN

Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform

0.390

SNX12_HUMAN

Sorting nexin-12

0.390

COR1C_HUMAN

Coronin-1C

0.391

NPRL2_HUMAN

GATOR complex protein NPRL2

0.392

ACON_HUMAN

Aconitate hydratase, mitochondrial

0.392

RRAGD_HUMAN

Ras-related GTP-binding protein D

0.392

TRM44_HUMAN

Probable tRNA (uracil-O(2)-)-methyltransferase

0.393

S2536_HUMAN

Solute carrier family 25 member 36

0.393

PBDC1_HUMAN

Protein PBDC1

0.393

SEPT7_HUMAN

Septin-7

0.393

CHLE_HUMAN

Cholinesterase

0.394

DPP6_HUMAN

Dipeptidyl aminopeptidase-like protein 6

0.395

RHOA_HUMAN

Transforming protein RhoA

0.395

PAXI_HUMAN

Paxillin

0.397

RRAGC_HUMAN

Ras-related GTP-binding protein C

0.397

S2533_HUMAN

Solute carrier family 25 member 33

0.397

RICTR_HUMAN

Rapamycin-insensitive companion of mTOR

0.398

PAN3_HUMAN

PAN2-PAN3 deadenylation complex subunit PAN3

0.398

RRAGA_HUMAN

Ras-related GTP-binding protein A

0.398

YLAT1_HUMAN

Y+L amino acid transporter 1

0.399

LIS1_HUMAN

Platelet-activating factor acetylhydrolase IB subunit alpha

0.400

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 87 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy