CF206_HUMAN 2019

Gene Name CF206

Description Cilia- and flagella-associated protein 206

Length 622

9606

Sequence

>sp|Q8IYR0|CF206_HUMAN Cilia- and flagella-associated protein 206
MPPTQAESVIRSIIREIGQECAAHGEIVSETLIAFMVKAVVLDPSNGFNMDRTLMKSDVQNLVKLCMTRLLDTKNPSLDTIKMQVYFDMNYTNRVEFLEEHHRVLESRLGSVTREITDNRACAKEELESLYRKIISYVLLRSGLGSPTDIKTVREVTAALQSVFPQAELGTFLTLSKKDKERQLKELTMIVTGIRLFNRDCGKGGEGIDDLPAVLHVAIPATMQHIDYQLETARSQVYRYTAILEKAANDPLMRAELQPYMLKEALYNIRQYEVFLQIILSDIITGAQEVEMMTKQLGAHLEQLKMTIKSKIAVPTSQVFPIFIALSTLWTSLQDETIVVGVLSNLFTHIQPFLGAHELYFPERVMQCHLNGATVKTDVCRMKEHMEDRVNVADFRKLEWLFPETTANFDKLLIQYRGFCAYTFAATDGLLLPGNPAIGILKYKEKYYTFNSKDAAYSFAENPEHYIDIVREKAKKNTELIQLLELHQQFETFIPYSQMRDADKHYIKPITKCESSTQTNTHILPPTIVRSYEWNEWELRRKAIKLANLRQKVTHSVQTDLSHLRRENCSQVYPPKDTSTQSMREDSTGVPRPQIYLAGLRGGKSEITDEVKVNLTRDVDET

Domains

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Help

What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

IDLC_HUMAN

Axonemal dynein light intermediate polypeptide 1

0.195

CFA52_HUMAN

Cilia- and flagella-associated protein 52

0.225

RSH4A_HUMAN

Radial spoke head protein 4 homolog A

0.228

CB5D1_HUMAN

Cytochrome b5 domain-containing protein 1

0.228

CFA43_HUMAN

Cilia- and flagella-associated protein 43

0.255

DRC4_HUMAN

Dynein regulatory complex subunit 4

0.271

RSPH9_HUMAN

Radial spoke head protein 9 homolog

0.277

DRC7_HUMAN

Dynein regulatory complex subunit 7

0.296

SPAG6_HUMAN

Sperm-associated antigen 6

0.296

HYDIN_HUMAN

Hydrocephalus-inducing protein homolog

0.298

DRC1_HUMAN

Dynein regulatory complex protein 1

0.300

RSPH3_HUMAN

Radial spoke head protein 3 homolog

0.302

CC113_HUMAN

Coiled-coil domain-containing protein 113

0.302

IF122_HUMAN

Intraflagellar transport protein 122 homolog

0.310

IFT56_HUMAN

Intraflagellar transport protein 56

0.310

CFA57_HUMAN

Cilia- and flagella-associated protein 57

0.314

IQUB_HUMAN

IQ and ubiquitin-like domain-containing protein

0.314

WDR63_HUMAN

WD repeat-containing protein 63

0.316

CCD40_HUMAN

Coiled-coil domain-containing protein 40

0.320

RSH6A_HUMAN

Radial spoke head protein 6 homolog A

0.322

DRC5_HUMAN

Dynein regulatory complex subunit 5

0.322

IFT57_HUMAN

Intraflagellar transport protein 57 homolog

0.327

IF172_HUMAN

Intraflagellar transport protein 172 homolog

0.329

WDR35_HUMAN

WD repeat-containing protein 35

0.329

DRC11_HUMAN

Dynein regulatory complex protein 11

0.333

CCD39_HUMAN

Coiled-coil domain-containing protein 39

0.335

CFA44_HUMAN

Cilia- and flagella-associated protein 44

0.340

CF251_HUMAN

Cilia- and flagella-associated protein 251

0.340

CASC1_HUMAN

Protein CASC1

0.344

PACRG_HUMAN

Parkin coregulated gene protein

0.345

TILB_HUMAN

Protein tilB homolog

0.345

IFT80_HUMAN

Intraflagellar transport protein 80 homolog

0.347

DNAL1_HUMAN

Dynein light chain 1, axonemal

0.351

CFA58_HUMAN

Cilia- and flagella-associated protein 58

0.354

IFT46_HUMAN

Intraflagellar transport protein 46 homolog

0.358

CFA91_HUMAN

Cilia- and flagella-associated protein 91

0.358

WDR19_HUMAN

WD repeat-containing protein 19

0.360

ZMY10_HUMAN

Zinc finger MYND domain-containing protein 10

0.360

CFA61_HUMAN

Cilia- and flagella-associated protein 61

0.360

IF140_HUMAN

Intraflagellar transport protein 140 homolog

0.362

DAAF5_HUMAN

Dynein assembly factor 5, axonemal

0.364

ENKUR_HUMAN

Enkurin

0.369

CFA45_HUMAN

Cilia- and flagella-associated protein 45

0.371

TT30B_HUMAN

Tetratricopeptide repeat protein 30B

0.371

CFA65_HUMAN

Cilia- and flagella-associated protein 65

0.373

CP100_HUMAN

Cilia- and flagella-associated protein 100

0.373

CCD42_HUMAN

Coiled-coil domain-containing protein 42

0.373

DRC3_HUMAN

Dynein regulatory complex subunit 3

0.374

EFHC1_HUMAN

EF-hand domain-containing protein 1

0.376

SSNA1_HUMAN

Sjoegren syndrome nuclear autoantigen 1

0.383

IFT52_HUMAN

Intraflagellar transport protein 52 homolog

0.384

TT30A_HUMAN

Tetratricopeptide repeat protein 30A

0.387

CCD63_HUMAN

Coiled-coil domain-containing protein 63

0.387

MIPT3_HUMAN

TRAF3-interacting protein 1

0.389

CE104_HUMAN

Centrosomal protein of 104 kDa

0.389

CP131_HUMAN

Centrosomal protein of 131 kDa

0.392

PIHD3_HUMAN

Protein PIH1D3

0.395

SPEF2_HUMAN

Sperm flagellar protein 2

0.395

ZMY12_HUMAN

Zinc finger MYND domain-containing protein 12

0.395

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

IDLC_HUMAN

Axonemal dynein light intermediate polypeptide 1

0.195

CFA52_HUMAN

Cilia- and flagella-associated protein 52

0.225

RSH4A_HUMAN

Radial spoke head protein 4 homolog A

0.228

CB5D1_HUMAN

Cytochrome b5 domain-containing protein 1

0.228

CFA43_HUMAN

Cilia- and flagella-associated protein 43

0.255

DRC4_HUMAN

Dynein regulatory complex subunit 4

0.271

RSPH9_HUMAN

Radial spoke head protein 9 homolog

0.277

DRC7_HUMAN

Dynein regulatory complex subunit 7

0.296

SPAG6_HUMAN

Sperm-associated antigen 6

0.296

HYDIN_HUMAN

Hydrocephalus-inducing protein homolog

0.298

DRC1_HUMAN

Dynein regulatory complex protein 1

0.300

RSPH3_HUMAN

Radial spoke head protein 3 homolog

0.302

CC113_HUMAN

Coiled-coil domain-containing protein 113

0.302

IF122_HUMAN

Intraflagellar transport protein 122 homolog

0.310

IFT56_HUMAN

Intraflagellar transport protein 56

0.310

CFA57_HUMAN

Cilia- and flagella-associated protein 57

0.314

IQUB_HUMAN

IQ and ubiquitin-like domain-containing protein

0.314

WDR63_HUMAN

WD repeat-containing protein 63

0.316

CCD40_HUMAN

Coiled-coil domain-containing protein 40

0.320

RSH6A_HUMAN

Radial spoke head protein 6 homolog A

0.322

DRC5_HUMAN

Dynein regulatory complex subunit 5

0.322

IFT57_HUMAN

Intraflagellar transport protein 57 homolog

0.327

IF172_HUMAN

Intraflagellar transport protein 172 homolog

0.329

WDR35_HUMAN

WD repeat-containing protein 35

0.329

DRC11_HUMAN

Dynein regulatory complex protein 11

0.333

CCD39_HUMAN

Coiled-coil domain-containing protein 39

0.335

CFA44_HUMAN

Cilia- and flagella-associated protein 44

0.340

CF251_HUMAN

Cilia- and flagella-associated protein 251

0.340

CASC1_HUMAN

Protein CASC1

0.344

PACRG_HUMAN

Parkin coregulated gene protein

0.345

TILB_HUMAN

Protein tilB homolog

0.345

IFT80_HUMAN

Intraflagellar transport protein 80 homolog

0.347

DNAL1_HUMAN

Dynein light chain 1, axonemal

0.351

CFA58_HUMAN

Cilia- and flagella-associated protein 58

0.354

IFT46_HUMAN

Intraflagellar transport protein 46 homolog

0.358

CFA91_HUMAN

Cilia- and flagella-associated protein 91

0.358

WDR19_HUMAN

WD repeat-containing protein 19

0.360

ZMY10_HUMAN

Zinc finger MYND domain-containing protein 10

0.360

CFA61_HUMAN

Cilia- and flagella-associated protein 61

0.360

IF140_HUMAN

Intraflagellar transport protein 140 homolog

0.362

DAAF5_HUMAN

Dynein assembly factor 5, axonemal

0.364

ENKUR_HUMAN

Enkurin

0.369

CFA45_HUMAN

Cilia- and flagella-associated protein 45

0.371

TT30B_HUMAN

Tetratricopeptide repeat protein 30B

0.371

CFA65_HUMAN

Cilia- and flagella-associated protein 65

0.373

CP100_HUMAN

Cilia- and flagella-associated protein 100

0.373

CCD42_HUMAN

Coiled-coil domain-containing protein 42

0.373

DRC3_HUMAN

Dynein regulatory complex subunit 3

0.374

EFHC1_HUMAN

EF-hand domain-containing protein 1

0.376

SSNA1_HUMAN

Sjoegren syndrome nuclear autoantigen 1

0.383

IFT52_HUMAN

Intraflagellar transport protein 52 homolog

0.384

TT30A_HUMAN

Tetratricopeptide repeat protein 30A

0.387

CCD63_HUMAN

Coiled-coil domain-containing protein 63

0.387

MIPT3_HUMAN

TRAF3-interacting protein 1

0.389

CE104_HUMAN

Centrosomal protein of 104 kDa

0.389

CP131_HUMAN

Centrosomal protein of 131 kDa

0.392

PIHD3_HUMAN

Protein PIH1D3

0.395

SPEF2_HUMAN

Sperm flagellar protein 2

0.395

ZMY12_HUMAN

Zinc finger MYND domain-containing protein 12

0.395

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 76 organisms (of 369)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy