SMAP_HUMAN 2019

Gene Name SMAP

Description Small acidic protein

Length 183

9606

Sequence

>sp|O00193|SMAP_HUMAN Small acidic protein
MSAARESHPHGVKRSASPDDDLGSSNWEAADLGNEERKQKFLRLMGAGKKEHTGRLVIGDHKSTSHFRTGEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKKDAKSNYKMMFVKSSGS

Domains

Loading...

Help

What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

No protein with similar profile across the domains were found

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

SYP2L_HUMAN

Synaptopodin 2-like protein

0.318

IRF4_HUMAN

Interferon regulatory factor 4

0.326

PC11X_HUMAN

Protocadherin-11 X-linked

0.326

PCDH9_HUMAN

Protocadherin-9

0.327

PCDH1_HUMAN

Protocadherin-1

0.341

DEDD_HUMAN

Death effector domain-containing protein

0.342

M3K14_HUMAN

Mitogen-activated protein kinase kinase kinase 14

0.349

IRF6_HUMAN

Interferon regulatory factor 6

0.352

PCD20_HUMAN

Protocadherin-20

0.357

CL029_HUMAN

Uncharacterized protein C12orf29

0.357

TM196_HUMAN

Transmembrane protein 196

0.358

NXPE3_HUMAN

NXPE family member 3

0.358

ZN451_HUMAN

E3 SUMO-protein ligase ZNF451

0.360

CIKS_HUMAN

Adapter protein CIKS

0.360

CLN6_HUMAN

Ceroid-lipofuscinosis neuronal protein 6

0.360

LPAR1_HUMAN

Lysophosphatidic acid receptor 1

0.362

S1PR1_HUMAN

Sphingosine 1-phosphate receptor 1

0.362

FBX38_HUMAN

F-box only protein 38

0.364

ZFAT_HUMAN

Zinc finger protein ZFAT

0.369

MYPN_HUMAN

Myopalladin

0.371

SLAI1_HUMAN

SLAIN motif-containing protein 1

0.371

IRF8_HUMAN

Interferon regulatory factor 8

0.371

I17RD_HUMAN

Interleukin-17 receptor D

0.373

PCD18_HUMAN

Protocadherin-18

0.373

AROS_HUMAN

Active regulator of SIRT1

0.373

CASC4_HUMAN

Protein CASC4

0.373

E4F1_HUMAN

Transcription factor E4F1

0.374

IBP5_HUMAN

Insulin-like growth factor-binding protein 5

0.374

ZN507_HUMAN

Zinc finger protein 507

0.374

PROS_HUMAN

Vitamin K-dependent protein S

0.376

F167A_HUMAN

Protein FAM167A

0.376

CF062_HUMAN

Uncharacterized protein C6orf62

0.380

ZN366_HUMAN

Zinc finger protein 366

0.380

NRP1_HUMAN

Neuropilin-1

0.381

PC11Y_HUMAN

Protocadherin-11 Y-linked

0.381

CNMD_HUMAN

Leukocyte cell-derived chemotaxin 1

0.383

TNF10_HUMAN

Tumor necrosis factor ligand superfamily member 10

0.383

SLAI2_HUMAN

SLAIN motif-containing protein 2

0.383

TR11B_HUMAN

Tumor necrosis factor receptor superfamily member 11B

0.383

MIEAP_HUMAN

Mitochondria-eating protein

0.384

HRH3_HUMAN

Histamine H3 receptor

0.385

CSF3R_HUMAN

Granulocyte colony-stimulating factor receptor

0.385

DZAN1_HUMAN

Double zinc ribbon and ankyrin repeat-containing protein 1

0.386

STC2_HUMAN

Stanniocalcin-2

0.387

ZN292_HUMAN

Zinc finger protein 292

0.387

STXB6_HUMAN

Syntaxin-binding protein 6

0.387

CXAR_HUMAN

Coxsackievirus and adenovirus receptor

0.387

SH3B4_HUMAN

SH3 domain-binding protein 4

0.387

TNIP2_HUMAN

TNFAIP3-interacting protein 2

0.387

PCOC2_HUMAN

Procollagen C-endopeptidase enhancer 2

0.387

BORG2_HUMAN

Cdc42 effector protein 3

0.387

T178B_HUMAN

Transmembrane protein 178B

0.387

PDZ11_HUMAN

PDZ domain-containing protein 11

0.390

FOXM1_HUMAN

Forkhead box protein M1

0.391

DBLOH_HUMAN

Diablo homolog, mitochondrial

0.391

TSN15_HUMAN

Tetraspanin-15

0.391

F199X_HUMAN

Protein FAM199X

0.391

CILP1_HUMAN

Cartilage intermediate layer protein 1

0.391

OPRK_HUMAN

Kappa-type opioid receptor

0.393

AF1L1_HUMAN

Actin filament-associated protein 1-like 1

0.393

AF1L2_HUMAN

Actin filament-associated protein 1-like 2

0.393

MPP9_HUMAN

M-phase phosphoprotein 9

0.393

PLXC1_HUMAN

Plexin-C1

0.393

MATR3_HUMAN

Matrin-3

0.395

VWC2L_HUMAN

von Willebrand factor C domain-containing protein 2-like

0.395

SPIT1_HUMAN

Kunitz-type protease inhibitor 1

0.395

I17RA_HUMAN

Interleukin-17 receptor A

0.395

TNR21_HUMAN

Tumor necrosis factor receptor superfamily member 21

0.395

MDH1B_HUMAN

Putative malate dehydrogenase 1B

0.396

NEXN_HUMAN

Nexilin

0.397

SYNG1_HUMAN

Synapse differentiation-inducing gene protein 1

0.397

PRLR_HUMAN

Prolactin receptor

0.397

NET4_HUMAN

Netrin-4

0.397

IMPG2_HUMAN

Interphotoreceptor matrix proteoglycan 2

0.397

HSPB7_HUMAN

Heat shock protein beta-7

0.397

STC1_HUMAN

Stanniocalcin-1

0.397

TXD16_HUMAN

Thioredoxin domain-containing protein 16

0.397

PARI_HUMAN

PCNA-interacting partner

0.397

NRP2_HUMAN

Neuropilin-2

0.397

TSN18_HUMAN

Tetraspanin-18

0.399

ATL2_HUMAN

ADAMTS-like protein 2

0.399

TNR5_HUMAN

Tumor necrosis factor receptor superfamily member 5

0.399

CEP55_HUMAN

Centrosomal protein of 55 kDa

0.399

CCD80_HUMAN

Coiled-coil domain-containing protein 80

0.399

CRBA1_HUMAN

Beta-crystallin A3

0.399

CD166_HUMAN

CD166 antigen

0.399

NR0B2_HUMAN

Nuclear receptor subfamily 0 group B member 2

0.399

PTN_HUMAN

Pleiotrophin

0.399

GPR12_HUMAN

G-protein coupled receptor 12

0.399

TPA_HUMAN

Tissue-type plasminogen activator

0.399

MACC1_HUMAN

Metastasis-associated in colon cancer protein 1

0.399

ZN142_HUMAN

Zinc finger protein 142

0.399

FBLN7_HUMAN

Fibulin-7

0.399

ITBP1_HUMAN

Integrin beta-1-binding protein 1

0.399

OTUL_HUMAN

Ubiquitin thioesterase otulin

0.399

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 27 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy