MAFG_HUMAN 2019

Gene Name MAFG

Description Transcription factor MafG

Length 162

9606

Sequence

>sp|O15525|MAFG_HUMAN Transcription factor MafG
MTTPNKGNKALKVKREPGENGTSLTDEELVTMSVRELNQHLRGLSKEEIVQLKQRRRTLKNRGYAASCRVKRVTQKEELEKQKAELQQEVEKLASENASMKLELDALRSKYEALQTFARTVARSPVAPARGPLAAGLGPLVPGKVAATSVITIVKSKTDARS

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

MAFK_HUMAN

Transcription factor MafK

0.152

CREL2_HUMAN

Cysteine-rich with EGF-like domain protein 2

0.323

FEM1C_HUMAN

Protein fem-1 homolog C

0.326

AKA10_HUMAN

A-kinase anchor protein 10, mitochondrial

0.330

PEBB_HUMAN

Core-binding factor subunit beta

0.330

TTC17_HUMAN

Tetratricopeptide repeat protein 17

0.330

IKKE_HUMAN

Inhibitor of nuclear factor kappa-B kinase subunit epsilon

0.333

TSHR_HUMAN

Thyrotropin receptor

0.333

CC85A_HUMAN

Coiled-coil domain-containing protein 85A

0.337

NF2L2_HUMAN

Nuclear factor erythroid 2-related factor 2

0.337

AIMP2_HUMAN

Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

0.341

RHG10_HUMAN

Rho GTPase-activating protein 10

0.350

PRIC2_HUMAN

Prickle-like protein 2

0.354

AGRL2_HUMAN

Adhesion G protein-coupled receptor L2

0.354

HLF_HUMAN

Hepatic leukemia factor

0.354

EPHA4_HUMAN

Ephrin type-A receptor 4

0.354

JPH1_HUMAN

Junctophilin-1

0.354

RHG42_HUMAN

Rho GTPase-activating protein 42

0.354

VAS1_HUMAN

V-type proton ATPase subunit S1

0.357

DDR2_HUMAN

Discoidin domain-containing receptor 2

0.357

CASP7_HUMAN

Caspase-7

0.357

XKR6_HUMAN

XK-related protein 6

0.361

DAB1_HUMAN

Disabled homolog 1

0.361

S12A8_HUMAN

Solute carrier family 12 member 8

0.361

PAR3L_HUMAN

Partitioning defective 3 homolog B

0.361

SPSB1_HUMAN

SPRY domain-containing SOCS box protein 1

0.361

CEBPG_HUMAN

CCAAT/enhancer-binding protein gamma

0.361

TTYH2_HUMAN

Protein tweety homolog 2

0.361

MBTD1_HUMAN

MBT domain-containing protein 1

0.365

TMCC3_HUMAN

Transmembrane and coiled-coil domain protein 3

0.365

NRF1_HUMAN

Nuclear respiratory factor 1

0.365

TRIB2_HUMAN

Tribbles homolog 2

0.365

NF2L1_HUMAN

Endoplasmic reticulum membrane sensor NFE2L1

0.365

CG026_HUMAN

Uncharacterized protein C7orf26

0.369

MED30_HUMAN

Mediator of RNA polymerase II transcription subunit 30

0.369

LMBL1_HUMAN

Lethal(3)malignant brain tumor-like protein 1

0.369

TAB1_HUMAN

TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

0.369

MAFB_HUMAN

Transcription factor MafB

0.374

RHG19_HUMAN

Rho GTPase-activating protein 19

0.374

SSR2_HUMAN

Somatostatin receptor type 2

0.374

SNX6_HUMAN

Sorting nexin-6

0.374

OFUT1_HUMAN

GDP-fucose protein O-fucosyltransferase 1

0.374

RT22_HUMAN

28S ribosomal protein S22, mitochondrial

0.378

CACB2_HUMAN

Voltage-dependent L-type calcium channel subunit beta-2

0.378

CPEB3_HUMAN

Cytoplasmic polyadenylation element-binding protein 3

0.378

WLS_HUMAN

Protein wntless homolog

0.378

CACB4_HUMAN

Voltage-dependent L-type calcium channel subunit beta-4

0.378

NONO_HUMAN

Non-POU domain-containing octamer-binding protein

0.382

AP2A_HUMAN

Transcription factor AP-2-alpha

0.382

TEF_HUMAN

Thyrotroph embryonic factor

0.382

TSN5_HUMAN

Tetraspanin-5

0.382

FOXO1_HUMAN

Forkhead box protein O1

0.382

PRIC1_HUMAN

Prickle-like protein 1

0.382

NFIA_HUMAN

Nuclear factor 1 A-type

0.382

AP2B_HUMAN

Transcription factor AP-2-beta

0.382

FOXO3_HUMAN

Forkhead box protein O3

0.382

CREL1_HUMAN

Cysteine-rich with EGF-like domain protein 1

0.382

NFIB_HUMAN

Nuclear factor 1 B-type

0.382

OPHN1_HUMAN

Oligophrenin-1

0.382

JPH3_HUMAN

Junctophilin-3

0.382

GO45_HUMAN

Golgin-45

0.386

ZER1_HUMAN

Protein zer-1 homolog

0.386

SFPQ_HUMAN

Splicing factor, proline- and glutamine-rich

0.386

NDUBA_HUMAN

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10

0.386

INTU_HUMAN

Protein inturned

0.386

KPCD1_HUMAN

Serine/threonine-protein kinase D1

0.386

DAG1_HUMAN

Dystroglycan

0.386

P66B_HUMAN

Transcriptional repressor p66-beta

0.390

ZN704_HUMAN

Zinc finger protein 704

0.390

DLP1_HUMAN

Decaprenyl-diphosphate synthase subunit 2

0.390

NAB1_HUMAN

NGFI-A-binding protein 1

0.390

P66A_HUMAN

Transcriptional repressor p66-alpha

0.390

DAB2_HUMAN

Disabled homolog 2

0.390

GRASP_HUMAN

General receptor for phosphoinositides 1-associated scaffold protein

0.390

HAND2_HUMAN

Heart- and neural crest derivatives-expressed protein 2

0.390

UBAP2_HUMAN

Ubiquitin-associated protein 2

0.390

JIP1_HUMAN

C-Jun-amino-terminal kinase-interacting protein 1

0.390

MCF2L_HUMAN

Guanine nucleotide exchange factor DBS

0.390

TXD11_HUMAN

Thioredoxin domain-containing protein 11

0.390

KANL1_HUMAN

KAT8 regulatory NSL complex subunit 1

0.394

SPSY_HUMAN

Spermine synthase

0.394

RYK_HUMAN

Tyrosine-protein kinase RYK

0.394

UBP31_HUMAN

Ubiquitin carboxyl-terminal hydrolase 31

0.394

EFNB2_HUMAN

Ephrin-B2

0.394

TBK1_HUMAN

Serine/threonine-protein kinase TBK1

0.394

TMCC1_HUMAN

Transmembrane and coiled-coil domains protein 1

0.394

FRITZ_HUMAN

WD repeat-containing and planar cell polarity effector protein fritz homolog

0.394

GNRHR_HUMAN

Gonadotropin-releasing hormone receptor

0.394

ECSIT_HUMAN

Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

0.396

ARFP1_HUMAN

Arfaptin-1

0.396

BTBDA_HUMAN

BTB/POZ domain-containing protein 10

0.396

SPIR2_HUMAN

Protein spire homolog 2

0.399

SP130_HUMAN

Histone deacetylase complex subunit SAP130

0.399

USH1G_HUMAN

Usher syndrome type-1G protein

0.399

GXLT2_HUMAN

Glucoside xylosyltransferase 2

0.399

RXFP1_HUMAN

Relaxin receptor 1

0.399

PPM1H_HUMAN

Protein phosphatase 1H

0.399

WNT1_HUMAN

Proto-oncogene Wnt-1

0.399

WHRN_HUMAN

Whirlin

0.399

TET3_HUMAN

Methylcytosine dioxygenase TET3

0.399

RGAP1_HUMAN

Rac GTPase-activating protein 1

0.400

FERM1_HUMAN

Fermitin family homolog 1

0.400

MIGA1_HUMAN

Mitoguardin 1

0.400

FGFR1_HUMAN

Fibroblast growth factor receptor 1

0.400

FERM2_HUMAN

Fermitin family homolog 2

0.400

SYT1_HUMAN

Synaptotagmin-1

0.400

RUNX2_HUMAN

Runt-related transcription factor 2

0.400

TET5A_HUMAN

Terminal nucleotidyltransferase 5A

0.400

ARHGB_HUMAN

Rho guanine nucleotide exchange factor 11

0.400

ANKL2_HUMAN

Ankyrin repeat and LEM domain-containing protein 2

0.400

FGFR2_HUMAN

Fibroblast growth factor receptor 2

0.400

BAF_HUMAN

Barrier-to-autointegration factor

0.400

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

MAFK_HUMAN

Transcription factor MafK

0.282

CC85A_HUMAN

Coiled-coil domain-containing protein 85A

0.397

CASP7_HUMAN

Caspase-7

0.399

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 43 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy