IFIT1_HUMAN 2019

Gene Name IFIT1

Description Interferon-induced protein with tetratricopeptide repeats 1

Length 478

9606

Sequence

>sp|P09914|IFIT1_HUMAN Interferon-induced protein with tetratricopeptide repeats 1
MSTNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAYVKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENSVRQGP

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

INS_HUMAN

Insulin

0.224

PRD15_HUMAN

PR domain zinc finger protein 15

0.309

HECA2_HUMAN

HEPACAM family member 2

0.316

CRBA2_HUMAN

Beta-crystallin A2

0.316

CHP3_HUMAN

Calcineurin B homologous protein 3

0.316

MPZL1_HUMAN

Myelin protein zero-like protein 1

0.316

CML1_HUMAN

Chemokine-like receptor 1

0.316

ZN319_HUMAN

Zinc finger protein 319

0.316

FETUB_HUMAN

Fetuin-B

0.316

EVPL_HUMAN

Envoplakin

0.316

K1C18_HUMAN

Keratin, type I cytoskeletal 18

0.316

BT1A1_HUMAN

Butyrophilin subfamily 1 member A1

0.316

HXC13_HUMAN

Homeobox protein Hox-C13

0.316

TM240_HUMAN

Transmembrane protein 240

0.316

TMG4_HUMAN

Transmembrane gamma-carboxyglutamic acid protein 4

0.316

CALC_HUMAN

Calcitonin

0.316

BHE40_HUMAN

Class E basic helix-loop-helix protein 40

0.369

HECAM_HUMAN

Hepatocyte cell adhesion molecule

0.378

SCN4B_HUMAN

Sodium channel subunit beta-4

0.378

NLRX1_HUMAN

NLR family member X1

0.378

XIRP2_HUMAN

Xin actin-binding repeat-containing protein 2

0.378

K1C19_HUMAN

Keratin, type I cytoskeletal 19

0.378

CEP68_HUMAN

Centrosomal protein of 68 kDa

0.378

CKLF3_HUMAN

CKLF-like MARVEL transmembrane domain-containing protein 3

0.378

CE024_HUMAN

UPF0461 protein C5orf24

0.378

ZBTB1_HUMAN

Zinc finger and BTB domain-containing protein 1

0.378

ZBT41_HUMAN

Zinc finger and BTB domain-containing protein 41

0.378

CCR7_HUMAN

C-C chemokine receptor type 7

0.378

IFFO1_HUMAN

Intermediate filament family orphan 1

0.378

VEZF1_HUMAN

Vascular endothelial zinc finger 1

0.378

SOCS1_HUMAN

Suppressor of cytokine signaling 1

0.378

ZN644_HUMAN

Zinc finger protein 644

0.378

SHL2A_HUMAN

Protein shisa-like-2A

0.378

SPI1_HUMAN

Transcription factor PU.1

0.378

MYOZ2_HUMAN

Myozenin-2

0.378

ANGT_HUMAN

Angiotensinogen

0.378

ZN516_HUMAN

Zinc finger protein 516

0.378

EMIL3_HUMAN

EMILIN-3

0.378

RGR_HUMAN

RPE-retinal G protein-coupled receptor

0.378

LBH_HUMAN

Protein LBH

0.378

PRDM5_HUMAN

PR domain zinc finger protein 5

0.378

BT2A1_HUMAN

Butyrophilin subfamily 2 member A1

0.378

GDNF_HUMAN

Glial cell line-derived neurotrophic factor

0.378

BAG5_HUMAN

BAG family molecular chaperone regulator 5

0.378

F1711_HUMAN

Protein FAM171A1

0.378

TEFF1_HUMAN

Tomoregulin-1

0.378

F163B_HUMAN

Protein FAM163B

0.378

F168B_HUMAN

Myelin-associated neurite-outgrowth inhibitor

0.378

PALM_HUMAN

Paralemmin-1

0.378

MYZAP_HUMAN

Myocardial zonula adherens protein

0.378

ZPLD1_HUMAN

Zona pellucida-like domain-containing protein 1

0.378

MALD3_HUMAN

MARVEL domain-containing protein 3

0.378

CLCF1_HUMAN

Cardiotrophin-like cytokine factor 1

0.378

LRC17_HUMAN

Leucine-rich repeat-containing protein 17

0.378

BFSP1_HUMAN

Filensin

0.378

LT4R1_HUMAN

Leukotriene B4 receptor 1

0.378

SDF1_HUMAN

Stromal cell-derived factor 1

0.378

ESM1_HUMAN

Endothelial cell-specific molecule 1

0.378

SCN2B_HUMAN

Sodium channel subunit beta-2

0.378

DSC2_HUMAN

Desmocollin-2

0.378

OTOSP_HUMAN

Otospiralin

0.378

UN93B_HUMAN

Protein unc-93 homolog B1

0.378

BT2A2_HUMAN

Butyrophilin subfamily 2 member A2

0.378

VTNC_HUMAN

Vitronectin

0.378

CCSE2_HUMAN

Serine-rich coiled-coil domain-containing protein 2

0.378

TSG6_HUMAN

Tumor necrosis factor-inducible gene 6 protein

0.378

CR025_HUMAN

Uncharacterized protein C18orf25

0.378

CLD11_HUMAN

Claudin-11

0.378

NRIP1_HUMAN

Nuclear receptor-interacting protein 1

0.378

BFSP2_HUMAN

Phakinin

0.378

G37L1_HUMAN

G-protein coupled receptor 37-like 1

0.378

DACT1_HUMAN

Dapper homolog 1

0.378

GDF9_HUMAN

Growth/differentiation factor 9

0.378

F168A_HUMAN

Protein FAM168A

0.378

SMS_HUMAN

Somatostatin

0.378

OLFM4_HUMAN

Olfactomedin-4

0.378

GHR_HUMAN

Growth hormone receptor

0.378

CCKN_HUMAN

Cholecystokinin

0.378

PEPL_HUMAN

Periplakin

0.378

ZBT18_HUMAN

Zinc finger and BTB domain-containing protein 18

0.378

CASP4_HUMAN

Caspase-4

0.378

A0A0G2JMH6_HUMAN

HLA-DRA

0.378

ZBTB2_HUMAN

Zinc finger and BTB domain-containing protein 2

0.378

AJAP1_HUMAN

Adherens junction-associated protein 1

0.378

FA83D_HUMAN

Protein FAM83D

0.378

TRIL_HUMAN

TLR4 interactor with leucine rich repeats

0.378

SHSL1_HUMAN

Protein shisa-like-1

0.378

TMM82_HUMAN

Transmembrane protein 82

0.378

TANK_HUMAN

TRAF family member-associated NF-kappa-B activator

0.378

CCG1_HUMAN

Voltage-dependent calcium channel gamma-1 subunit

0.378

NXPH2_HUMAN

Neurexophilin-2

0.378

CABP1_HUMAN

Calcium-binding protein 1

0.378

K121L_HUMAN

Uncharacterized protein KIAA1211-like

0.378

MYBPH_HUMAN

Myosin-binding protein H

0.378

RAG2_HUMAN

V(D)J recombination-activating protein 2

0.378

MFA3L_HUMAN

Microfibrillar-associated protein 3-like

0.378

DRA_HUMAN

HLA class II histocompatibility antigen, DR alpha chain

0.378

PDGFD_HUMAN

Platelet-derived growth factor D

0.378

CLD18_HUMAN

Claudin-18

0.378

GP182_HUMAN

G-protein coupled receptor 182

0.378

MBP_HUMAN

Myelin basic protein

0.378

VISTA_HUMAN

V-type immunoglobulin domain-containing suppressor of T-cell activation

0.378

PENK_HUMAN

Proenkephalin-A

0.378

SPIN1_HUMAN

Spindlin-1

0.378

ITGBL_HUMAN

Integrin beta-like protein 1

0.378

ALPK3_HUMAN

Alpha-protein kinase 3

0.378

CXA5_HUMAN

Gap junction alpha-5 protein

0.378

ZFP91_HUMAN

E3 ubiquitin-protein ligase ZFP91

0.378

NYAP2_HUMAN

Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2

0.378

GEMC1_HUMAN

Geminin coiled-coil domain-containing protein 1

0.378

SARG_HUMAN

Specifically androgen-regulated gene protein

0.378

APOH_HUMAN

Beta-2-glycoprotein 1

0.378

ACKR3_HUMAN

Atypical chemokine receptor 3

0.378

LXN_HUMAN

Latexin

0.378

GP183_HUMAN

G-protein coupled receptor 183

0.378

TM125_HUMAN

Transmembrane protein 125

0.378

ZP3_HUMAN

Zona pellucida sperm-binding protein 3

0.378

MLC1_HUMAN

Membrane protein MLC1

0.378

SCG2_HUMAN

Secretogranin-2

0.378

ZN276_HUMAN

Zinc finger protein 276

0.378

VSTM4_HUMAN

V-set and transmembrane domain-containing protein 4

0.378

CO9A3_HUMAN

Collagen alpha-3(IX) chain

0.378

ZBT14_HUMAN

Zinc finger and BTB domain-containing protein 14

0.378

AUGN_HUMAN

Augurin

0.378

RGCC_HUMAN

Regulator of cell cycle RGCC

0.378

M3K8_HUMAN

Mitogen-activated protein kinase kinase kinase 8

0.378

FAKD2_HUMAN

FAST kinase domain-containing protein 2, mitochondrial

0.378

SLAP1_HUMAN

Src-like-adapter

0.378

CRAD_HUMAN

Cancer-related regulator of actin dynamics

0.378

PDGFC_HUMAN

Platelet-derived growth factor C

0.378

PXDC1_HUMAN

PX domain-containing protein 1

0.378

NHSL1_HUMAN

NHS-like protein 1

0.378

TSN1_HUMAN

Tetraspanin-1

0.378

MAML2_HUMAN

Mastermind-like protein 2

0.378

PHAG1_HUMAN

Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

0.378

ZN131_HUMAN

Zinc finger protein 131

0.378

COLI_HUMAN

Pro-opiomelanocortin

0.378

SYNEM_HUMAN

Synemin

0.378

FGF19_HUMAN

Fibroblast growth factor 19

0.378

TM263_HUMAN

Transmembrane protein 263

0.378

MERB1_HUMAN

bMERB domain-containing protein 1

0.378

CCPG1_HUMAN

Cell cycle progression protein 1

0.378

VCAM1_HUMAN

Vascular cell adhesion protein 1

0.378

EVA1B_HUMAN

Protein eva-1 homolog B

0.378

ZBT20_HUMAN

Zinc finger and BTB domain-containing protein 20

0.378

NPY_HUMAN

Pro-neuropeptide Y

0.378

ANDR_HUMAN

Androgen receptor

0.378

TF_HUMAN

Tissue factor

0.378

CEP55_HUMAN

Centrosomal protein of 55 kDa

0.378

KDF1_HUMAN

Keratinocyte differentiation factor 1

0.378

PALMD_HUMAN

Palmdelphin

0.378

RIPL2_HUMAN

RILP-like protein 2

0.378

CDCP1_HUMAN

CUB domain-containing protein 1

0.378

CA159_HUMAN

Uncharacterized protein C1orf159

0.378

PTAFR_HUMAN

Platelet-activating factor receptor

0.378

CXD2_HUMAN

Gap junction delta-2 protein

0.378

GP176_HUMAN

G-protein coupled receptor 176

0.378

WIZ_HUMAN

Protein Wiz

0.378

ABEC2_HUMAN

C->U-editing enzyme APOBEC-2

0.378

S100Z_HUMAN

Protein S100-Z

0.378

CKAP4_HUMAN

Cytoskeleton-associated protein 4

0.378

TSN10_HUMAN

Tetraspanin-10

0.378

LEGL_HUMAN

Galectin-related protein

0.378

SUSD6_HUMAN

Sushi domain-containing protein 6

0.378

PRL_HUMAN

Prolactin

0.378

PPDPF_HUMAN

Pancreatic progenitor cell differentiation and proliferation factor

0.378

MTURN_HUMAN

Maturin

0.378

REST_HUMAN

RE1-silencing transcription factor

0.378

GPR39_HUMAN

G-protein coupled receptor 39

0.378

P33MX_HUMAN

Putative monooxygenase p33MONOX

0.378

PPR1C_HUMAN

Protein phosphatase 1 regulatory subunit 1C

0.378

VIP_HUMAN

VIP peptides

0.378

NSG2_HUMAN

Neuronal vesicle trafficking-associated protein 2

0.378

TRADD_HUMAN

Tumor necrosis factor receptor type 1-associated DEATH domain protein

0.378

FPRP_HUMAN

Prostaglandin F2 receptor negative regulator

0.378

CAVN1_HUMAN

Caveolae-associated protein 1

0.378

NEXMI_HUMAN

Neurite extension and migration factor

0.378

SGO1_HUMAN

Shugoshin 1

0.378

ZN536_HUMAN

Zinc finger protein 536

0.378

FA83H_HUMAN

Protein FAM83H

0.378

TNR6_HUMAN

Tumor necrosis factor receptor superfamily member 6

0.378

FNDC7_HUMAN

Fibronectin type III domain-containing protein 7

0.378

MXRA8_HUMAN

Matrix remodeling-associated protein 8

0.378

APJ_HUMAN

Apelin receptor

0.378

TRH_HUMAN

Pro-thyrotropin-releasing hormone

0.378

SUSD1_HUMAN

Sushi domain-containing protein 1

0.378

UROL1_HUMAN

Uromodulin-like 1

0.378

AMGO1_HUMAN

Amphoterin-induced protein 1

0.378

DSC1_HUMAN

Desmocollin-1

0.378

ZBT24_HUMAN

Zinc finger and BTB domain-containing protein 24

0.378

TM182_HUMAN

Transmembrane protein 182

0.378

CDHR1_HUMAN

Cadherin-related family member 1

0.378

SYNE3_HUMAN

Nesprin-3

0.378

IL12B_HUMAN

Interleukin-12 subunit beta

0.378

PRELP_HUMAN

Prolargin

0.378

CRGN_HUMAN

Gamma-crystallin N

0.378

MNAR1_HUMAN

Major intrinsically disordered Notch2-binding receptor 1

0.378

PTHR_HUMAN

Parathyroid hormone-related protein

0.378

AKA12_HUMAN

A-kinase anchor protein 12

0.378

SKA3_HUMAN

Spindle and kinetochore-associated protein 3

0.378

OCLN_HUMAN

Occludin

0.378

OX2G_HUMAN

OX-2 membrane glycoprotein

0.378

PI3R6_HUMAN

Phosphoinositide 3-kinase regulatory subunit 6

0.378

MRAP2_HUMAN

Melanocortin-2 receptor accessory protein 2

0.378

TMM51_HUMAN

Transmembrane protein 51

0.378

RAMP1_HUMAN

Receptor activity-modifying protein 1

0.378

MPZL2_HUMAN

Myelin protein zero-like protein 2

0.378

ERRFI_HUMAN

ERBB receptor feedback inhibitor 1

0.378

NXPH1_HUMAN

Neurexophilin-1

0.378

MIME_HUMAN

Mimecan

0.378

LEG1_HUMAN

Galectin-1

0.378

ZBT16_HUMAN

Zinc finger and BTB domain-containing protein 16

0.378

IKIP_HUMAN

Inhibitor of nuclear factor kappa-B kinase-interacting protein

0.378

CFAI_HUMAN

Complement factor I

0.378

AKA11_HUMAN

A-kinase anchor protein 11

0.378

LRTM2_HUMAN

Leucine-rich repeat and transmembrane domain-containing protein 2

0.378

K1C17_HUMAN

Keratin, type I cytoskeletal 17

0.378

NUFP2_HUMAN

Nuclear fragile X mental retardation-interacting protein 2

0.378

T4S4_HUMAN

Transmembrane 4 L6 family member 4

0.378

CAR19_HUMAN

Caspase recruitment domain-containing protein 19

0.378

CRP_HUMAN

C-reactive protein

0.378

FMOD_HUMAN

Fibromodulin

0.378

SUSD3_HUMAN

Sushi domain-containing protein 3

0.378

ZN335_HUMAN

Zinc finger protein 335

0.378

CXCR4_HUMAN

C-X-C chemokine receptor type 4

0.378

CAVN2_HUMAN

Caveolae-associated protein 2

0.378

VWA1_HUMAN

von Willebrand factor A domain-containing protein 1

0.378

LEPR_HUMAN

Leptin receptor

0.378

MMP23_HUMAN

Matrix metalloproteinase-23

0.378

TM204_HUMAN

Transmembrane protein 204

0.378

NEUM_HUMAN

Neuromodulin

0.378

SP2_HUMAN

Transcription factor Sp2

0.378

CLD22_HUMAN

Claudin-22

0.378

MYADM_HUMAN

Myeloid-associated differentiation marker

0.387

PMEL_HUMAN

Melanocyte protein PMEL

0.387

BRI3B_HUMAN

BRI3-binding protein

0.387

CCSE1_HUMAN

Serine-rich coiled-coil domain-containing protein 1

0.387

CTXN3_HUMAN

Cortexin-3

0.387

TM108_HUMAN

Transmembrane protein 108

0.387

TBKB1_HUMAN

TANK-binding kinase 1-binding protein 1

0.387

TMG3_HUMAN

Transmembrane gamma-carboxyglutamic acid protein 3

0.387

IFM2_HUMAN

Interferon-induced transmembrane protein 2

0.387

OGR1_HUMAN

Ovarian cancer G-protein coupled receptor 1

0.387

DDIT3_HUMAN

DNA damage-inducible transcript 3 protein

0.387

CLM7_HUMAN

CMRF35-like molecule 7

0.387

TAFA5_HUMAN

Chemokine-like protein TAFA-5

0.387

ARMX3_HUMAN

Armadillo repeat-containing X-linked protein 3

0.387

THMS2_HUMAN

Protein THEMIS2

0.387

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

CXD2_HUMAN

Gap junction delta-2 protein

0.346

ZN335_HUMAN

Zinc finger protein 335

0.346

F1711_HUMAN

Protein FAM171A1

0.346

CKLF3_HUMAN

CKLF-like MARVEL transmembrane domain-containing protein 3

0.346

CLD11_HUMAN

Claudin-11

0.346

FMOD_HUMAN

Fibromodulin

0.346

CCR7_HUMAN

C-C chemokine receptor type 7

0.346

ZBTB2_HUMAN

Zinc finger and BTB domain-containing protein 2

0.346

MALD3_HUMAN

MARVEL domain-containing protein 3

0.350

GAK1B_HUMAN

Golgi-associated kinase 1B

0.357

BEND4_HUMAN

BEN domain-containing protein 4

0.357

PENK_HUMAN

Proenkephalin-A

0.359

OCLN_HUMAN

Occludin

0.359

ZN644_HUMAN

Zinc finger protein 644

0.359

ADNP_HUMAN

Activity-dependent neuroprotector homeobox protein

0.359

GHR_HUMAN

Growth hormone receptor

0.359

SYBU_HUMAN

Syntabulin

0.359

LEG1_HUMAN

Galectin-1

0.359

BEND7_HUMAN

BEN domain-containing protein 7

0.359

SGO1_HUMAN

Shugoshin 1

0.359

MERB1_HUMAN

bMERB domain-containing protein 1

0.359

VSTM4_HUMAN

V-set and transmembrane domain-containing protein 4

0.359

MFA3L_HUMAN

Microfibrillar-associated protein 3-like

0.359

MYZAP_HUMAN

Myocardial zonula adherens protein

0.359

ZPLD1_HUMAN

Zona pellucida-like domain-containing protein 1

0.359

PDGFC_HUMAN

Platelet-derived growth factor C

0.359

CFLAR_HUMAN

CASP8 and FADD-like apoptosis regulator

0.359

ZN131_HUMAN

Zinc finger protein 131

0.359

LARGN_HUMAN

Protein Largen

0.359

NPY_HUMAN

Pro-neuropeptide Y

0.359

PRL_HUMAN

Prolactin

0.359

NEXMI_HUMAN

Neurite extension and migration factor

0.359

P33MX_HUMAN

Putative monooxygenase p33MONOX

0.359

PEPL_HUMAN

Periplakin

0.361

ZBT20_HUMAN

Zinc finger and BTB domain-containing protein 20

0.361

ERRFI_HUMAN

ERBB receptor feedback inhibitor 1

0.361

CCPG1_HUMAN

Cell cycle progression protein 1

0.361

OLFL3_HUMAN

Olfactomedin-like protein 3

0.361

EVPL_HUMAN

Envoplakin

0.361

TSN1_HUMAN

Tetraspanin-1

0.361

CAVN2_HUMAN

Caveolae-associated protein 2

0.361

FETUB_HUMAN

Fetuin-B

0.361

GP176_HUMAN

G-protein coupled receptor 176

0.361

F222B_HUMAN

Protein FAM222B

0.361

F168B_HUMAN

Myelin-associated neurite-outgrowth inhibitor

0.361

AKA12_HUMAN

A-kinase anchor protein 12

0.361

GDF9_HUMAN

Growth/differentiation factor 9

0.361

PRLR_HUMAN

Prolactin receptor

0.370

CCD80_HUMAN

Coiled-coil domain-containing protein 80

0.372

CEP55_HUMAN

Centrosomal protein of 55 kDa

0.372

ZN142_HUMAN

Zinc finger protein 142

0.372

CD166_HUMAN

CD166 antigen

0.372

GCR_HUMAN

Glucocorticoid receptor

0.372

ASB4_HUMAN

Ankyrin repeat and SOCS box protein 4

0.372

TF_HUMAN

Tissue factor

0.374

NLRX1_HUMAN

NLR family member X1

0.374

CCSE2_HUMAN

Serine-rich coiled-coil domain-containing protein 2

0.374

ABEC2_HUMAN

C->U-editing enzyme APOBEC-2

0.374

F131B_HUMAN

Protein FAM131B

0.374

GDNF_HUMAN

Glial cell line-derived neurotrophic factor

0.374

EDAR_HUMAN

Tumor necrosis factor receptor superfamily member EDAR

0.374

ZBTB1_HUMAN

Zinc finger and BTB domain-containing protein 1

0.374

RAG2_HUMAN

V(D)J recombination-activating protein 2

0.374

BFSP1_HUMAN

Filensin

0.374

FPRP_HUMAN

Prostaglandin F2 receptor negative regulator

0.374

CXCR4_HUMAN

C-X-C chemokine receptor type 4

0.374

TEFF1_HUMAN

Tomoregulin-1

0.374

CDCP1_HUMAN

CUB domain-containing protein 1

0.374

TANK_HUMAN

TRAF family member-associated NF-kappa-B activator

0.374

TMM51_HUMAN

Transmembrane protein 51

0.374

M3K8_HUMAN

Mitogen-activated protein kinase kinase kinase 8

0.374

MNAR1_HUMAN

Major intrinsically disordered Notch2-binding receptor 1

0.374

LGI1_HUMAN

Leucine-rich glioma-inactivated protein 1

0.374

SPIN1_HUMAN

Spindlin-1

0.374

ZP3_HUMAN

Zona pellucida sperm-binding protein 3

0.374

MBP_HUMAN

Myelin basic protein

0.374

RAB12_HUMAN

Ras-related protein Rab-12

0.374

LUZP1_HUMAN

Leucine zipper protein 1

0.374

PRDM5_HUMAN

PR domain zinc finger protein 5

0.374

ITGBL_HUMAN

Integrin beta-like protein 1

0.374

CAD17_HUMAN

Cadherin-17

0.374

LUR1L_HUMAN

Leucine rich adaptor protein 1-like

0.374

NYAP2_HUMAN

Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2

0.374

AKA11_HUMAN

A-kinase anchor protein 11

0.374

ZBT18_HUMAN

Zinc finger and BTB domain-containing protein 18

0.374

LYRIC_HUMAN

Protein LYRIC

0.374

PHAG1_HUMAN

Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

0.374

VCAM1_HUMAN

Vascular cell adhesion protein 1

0.374

ZBT16_HUMAN

Zinc finger and BTB domain-containing protein 16

0.374

SKA3_HUMAN

Spindle and kinetochore-associated protein 3

0.374

PALMD_HUMAN

Palmdelphin

0.374

ANGT_HUMAN

Angiotensinogen

0.374

PTHR_HUMAN

Parathyroid hormone-related protein

0.374

SMS_HUMAN

Somatostatin

0.374

AZI2_HUMAN

5-azacytidine-induced protein 2

0.374

LEPR_HUMAN

Leptin receptor

0.374

OGR1_HUMAN

Ovarian cancer G-protein coupled receptor 1

0.376

OX2G_HUMAN

OX-2 membrane glycoprotein

0.376

C99L2_HUMAN

CD99 antigen-like protein 2

0.376

ZBT14_HUMAN

Zinc finger and BTB domain-containing protein 14

0.376

DSG2_HUMAN

Desmoglein-2

0.376

IN35_HUMAN

Interferon-induced 35 kDa protein

0.376

ZN711_HUMAN

Zinc finger protein 711

0.376

SYNCI_HUMAN

Syncoilin

0.376

ESM1_HUMAN

Endothelial cell-specific molecule 1

0.376

PCD10_HUMAN

Protocadherin-10

0.376

DSC2_HUMAN

Desmocollin-2

0.376

MYOZ2_HUMAN

Myozenin-2

0.376

GP149_HUMAN

Probable G-protein coupled receptor 149

0.376

NRIP1_HUMAN

Nuclear receptor-interacting protein 1

0.376

MAL2_HUMAN

Protein MAL2

0.376

BFSP2_HUMAN

Phakinin

0.376

GPR39_HUMAN

G-protein coupled receptor 39

0.376

CKAP4_HUMAN

Cytoskeleton-associated protein 4

0.376

INSY2_HUMAN

Inhibitory synaptic factor 2A

0.378

COLI_HUMAN

Pro-opiomelanocortin

0.378

SCN2B_HUMAN

Sodium channel subunit beta-2

0.378

RAMP1_HUMAN

Receptor activity-modifying protein 1

0.378

PRDM2_HUMAN

PR domain zinc finger protein 2

0.382

CCG1_HUMAN

Voltage-dependent calcium channel gamma-1 subunit

0.384

LEGL_HUMAN

Galectin-related protein

0.384

FABP6_HUMAN

Gastrotropin

0.384

RIC3_HUMAN

Protein RIC-3

0.384

EURL_HUMAN

Protein EURL homolog

0.384

CXAR_HUMAN

Coxsackievirus and adenovirus receptor

0.384

BORG2_HUMAN

Cdc42 effector protein 3

0.384

STXB6_HUMAN

Syntaxin-binding protein 6

0.384

STC2_HUMAN

Stanniocalcin-2

0.384

PXDC1_HUMAN

PX domain-containing protein 1

0.386

STYK1_HUMAN

Tyrosine-protein kinase STYK1

0.386

NHSL1_HUMAN

NHS-like protein 1

0.386

CALD1_HUMAN

Caldesmon

0.386

EPYC_HUMAN

Epiphycan

0.386

CO8A_HUMAN

Complement component C8 alpha chain

0.386

TM263_HUMAN

Transmembrane protein 263

0.386

PCD19_HUMAN

Protocadherin-19

0.386

TR19L_HUMAN

Tumor necrosis factor receptor superfamily member 19L

0.386

CDHR1_HUMAN

Cadherin-related family member 1

0.386

PEDF_HUMAN

Pigment epithelium-derived factor

0.386

FAKD2_HUMAN

FAST kinase domain-containing protein 2, mitochondrial

0.386

AGRF5_HUMAN

Adhesion G protein-coupled receptor F5

0.386

ASTN1_HUMAN

Astrotactin-1

0.386

EMP2_HUMAN

Epithelial membrane protein 2

0.386

CRBB1_HUMAN

Beta-crystallin B1

0.386

ZBT10_HUMAN

Zinc finger and BTB domain-containing protein 10

0.386

BAG5_HUMAN

BAG family molecular chaperone regulator 5

0.388

XIRP2_HUMAN

Xin actin-binding repeat-containing protein 2

0.388

AGR2_HUMAN

Anterior gradient protein 2 homolog

0.388

TR150_HUMAN

Thyroid hormone receptor-associated protein 3

0.388

SOGA1_HUMAN

Protein SOGA1

0.388

GPC5C_HUMAN

G-protein coupled receptor family C group 5 member C

0.388

F163B_HUMAN

Protein FAM163B

0.388

IKIP_HUMAN

Inhibitor of nuclear factor kappa-B kinase-interacting protein

0.388

HBEGF_HUMAN

Proheparin-binding EGF-like growth factor

0.388

REST_HUMAN

RE1-silencing transcription factor

0.388

CFAI_HUMAN

Complement factor I

0.388

JCAD_HUMAN

Junctional protein associated with coronary artery disease

0.388

K1107_HUMAN

AP2-interacting clathrin-endocytosis protein

0.388

F180A_HUMAN

Protein FAM180A

0.388

F168A_HUMAN

Protein FAM168A

0.388

SCF_HUMAN

Kit ligand

0.388

TRH_HUMAN

Pro-thyrotropin-releasing hormone

0.388

SUSD1_HUMAN

Sushi domain-containing protein 1

0.388

UIF_HUMAN

UAP56-interacting factor

0.388

ZN652_HUMAN

Zinc finger protein 652

0.388

ESAM_HUMAN

Endothelial cell-selective adhesion molecule

0.388

PRELP_HUMAN

Prolargin

0.388

ACKR3_HUMAN

Atypical chemokine receptor 3

0.388

OLFM4_HUMAN

Olfactomedin-4

0.388

SARG_HUMAN

Specifically androgen-regulated gene protein

0.388

MFR1L_HUMAN

Mitochondrial fission regulator 1-like

0.388

K1549_HUMAN

UPF0606 protein KIAA1549

0.388

ZN148_HUMAN

Zinc finger protein 148

0.388

APOH_HUMAN

Beta-2-glycoprotein 1

0.388

FNDC7_HUMAN

Fibronectin type III domain-containing protein 7

0.388

R7BP_HUMAN

Regulator of G-protein signaling 7-binding protein

0.388

TM182_HUMAN

Transmembrane protein 182

0.388

SCN3B_HUMAN

Sodium channel subunit beta-3

0.388

SYNEM_HUMAN

Synemin

0.388

HECAM_HUMAN

Hepatocyte cell adhesion molecule

0.388

CC126_HUMAN

Coiled-coil domain-containing protein 126

0.388

SLIK1_HUMAN

SLIT and NTRK-like protein 1

0.388

SUSD6_HUMAN

Sushi domain-containing protein 6

0.388

CMGA_HUMAN

Chromogranin-A

0.388

MIME_HUMAN

Mimecan

0.388

F131A_HUMAN

Protein FAM131A

0.388

NUFP2_HUMAN

Nuclear fragile X mental retardation-interacting protein 2

0.388

MAL_HUMAN

Myelin and lymphocyte protein

0.388

TSG6_HUMAN

Tumor necrosis factor-inducible gene 6 protein

0.388

MRAP2_HUMAN

Melanocortin-2 receptor accessory protein 2

0.388

BSPRY_HUMAN

B box and SPRY domain-containing protein

0.388

PGFRL_HUMAN

Platelet-derived growth factor receptor-like protein

0.388

MYCT1_HUMAN

Myc target protein 1

0.390

IL20_HUMAN

Interleukin-20

0.390

SLAP1_HUMAN

Src-like-adapter

0.390

TRADD_HUMAN

Tumor necrosis factor receptor type 1-associated DEATH domain protein

0.390

MYBPH_HUMAN

Myosin-binding protein H

0.390

FA83D_HUMAN

Protein FAM83D

0.390

MCR_HUMAN

Mineralocorticoid receptor

0.390

CHP3_HUMAN

Calcineurin B homologous protein 3

0.390

BRI3B_HUMAN

BRI3-binding protein

0.390

VTM2L_HUMAN

V-set and transmembrane domain-containing protein 2-like protein

0.390

EMIL2_HUMAN

EMILIN-2

0.390

ANGL3_HUMAN

Angiopoietin-related protein 3

0.390

BMF_HUMAN

Bcl-2-modifying factor

0.392

GP183_HUMAN

G-protein coupled receptor 183

0.392

RET4_HUMAN

Retinol-binding protein 4

0.393

MATR3_HUMAN

Matrin-3

0.393

AROS_HUMAN

Active regulator of SIRT1

0.393

CASC4_HUMAN

Protein CASC4

0.393

GPBL1_HUMAN

Vasculin-like protein 1

0.393

K1C19_HUMAN

Keratin, type I cytoskeletal 19

0.394

MCL1_HUMAN

Induced myeloid leukemia cell differentiation protein Mcl-1

0.395

NET4_HUMAN

Netrin-4

0.395

HMGX3_HUMAN

HMG domain-containing protein 3

0.395

NEXN_HUMAN

Nexilin

0.395

FNDC1_HUMAN

Fibronectin type III domain-containing protein 1

0.395

STC1_HUMAN

Stanniocalcin-1

0.395

FANCC_HUMAN

Fanconi anemia group C protein

0.395

TPA_HUMAN

Tissue-type plasminogen activator

0.397

KLH42_HUMAN

Kelch-like protein 42

0.397

FBLN7_HUMAN

Fibulin-7

0.397

BCL9_HUMAN

B-cell CLL/lymphoma 9 protein

0.397

TSN18_HUMAN

Tetraspanin-18

0.397

T150A_HUMAN

Transmembrane protein 150A

0.397

MC4R_HUMAN

Melanocortin receptor 4

0.397

CRBA1_HUMAN

Beta-crystallin A3

0.397

PROS_HUMAN

Vitamin K-dependent protein S

0.397

VEGFA_HUMAN

Vascular endothelial growth factor A

0.397

VEZF1_HUMAN

Vascular endothelial zinc finger 1

0.397

TM206_HUMAN

Transmembrane protein 206

0.397

PTN_HUMAN

Pleiotrophin

0.397

TSN12_HUMAN

Tetraspanin-12

0.397

RGR_HUMAN

RPE-retinal G protein-coupled receptor

0.397

ZFP91_HUMAN

E3 ubiquitin-protein ligase ZFP91

0.397

VTNC_HUMAN

Vitronectin

0.397

NR0B2_HUMAN

Nuclear receptor subfamily 0 group B member 2

0.397

SRPX2_HUMAN

Sushi repeat-containing protein SRPX2

0.397

IFIT5_HUMAN

Interferon-induced protein with tetratricopeptide repeats 5

0.399

LGI2_HUMAN

Leucine-rich repeat LGI family member 2

0.399

SCG3_HUMAN

Secretogranin-3

0.399

ZN276_HUMAN

Zinc finger protein 276

0.399

UN93B_HUMAN

Protein unc-93 homolog B1

0.399

LRAD3_HUMAN

Low-density lipoprotein receptor class A domain-containing protein 3

0.399

RFTN2_HUMAN

Raftlin-2

0.399

MUC18_HUMAN

Cell surface glycoprotein MUC18

0.399

SRPX_HUMAN

Sushi repeat-containing protein SRPX

0.399

LRC52_HUMAN

Leucine-rich repeat-containing protein 52

0.399

PRD15_HUMAN

PR domain zinc finger protein 15

0.399

ZN438_HUMAN

Zinc finger protein 438

0.399

CLD10_HUMAN

Claudin-10

0.399

GPNMB_HUMAN

Transmembrane glycoprotein NMB

0.399

CDCA2_HUMAN

Cell division cycle-associated protein 2

0.399

SYNE3_HUMAN

Nesprin-3

0.399

NAIF1_HUMAN

Nuclear apoptosis-inducing factor 1

0.399

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 18 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy