GIMD1_HUMAN 2019

Gene Name GIMD1

Description GTPase IMAP family member GIMD1

Length 217

9606

Sequence

>sp|P0DJR0|GIMD1_HUMAN GTPase IMAP family member GIMD1
MTDPNKMIINLALFGMTQSGKSSAGNILLGSTDFHSSFAPCSVTTCCSLGRSCHLHSFMRRGGLEVALQVQVLDTPGYPHSRLSKKYVKQEVKEALAHHFGQGGLHLALLVQRADVPFCGQEVTDPVQMIQELLGHAWMNYTAILFTHAEKIEEAGLTEDKYLHEASDTLKTLLNSIQHKYVFQYKKGKSLNEQRMKILERIMEFIKENCYQVLTFK

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

AKND1_HUMAN

Protein AKNAD1

0.000

ICOSL_HUMAN

ICOS ligand

0.000

KCD18_HUMAN

BTB/POZ domain-containing protein KCTD18

0.267

PIANP_HUMAN

PILR alpha-associated neural protein

0.267

IL18_HUMAN

Interleukin-18

0.267

PARM1_HUMAN

Prostate androgen-regulated mucin-like protein 1

0.267

CLD16_HUMAN

Claudin-16

0.267

TRI14_HUMAN

Tripartite motif-containing protein 14

0.267

MFAP3_HUMAN

Microfibril-associated glycoprotein 3

0.267

MSLN_HUMAN

Mesothelin

0.267

VWCE_HUMAN

von Willebrand factor C and EGF domain-containing protein

0.267

GPR15_HUMAN

G-protein coupled receptor 15

0.277

TPO_HUMAN

Thrombopoietin

0.277

SMCO3_HUMAN

Single-pass membrane and coiled-coil domain-containing protein 3

0.277

A0A087X1L8_HUMAN

Uncharacterized protein

0.277

CAMP_HUMAN

Cathelicidin antimicrobial peptide

0.277

VSIG4_HUMAN

V-set and immunoglobulin domain-containing protein 4

0.277

L37A3_HUMAN

Leucine-rich repeat-containing protein 37A3

0.277

IQCJ_HUMAN

IQ domain-containing protein J

0.277

SACA1_HUMAN

Sperm acrosome membrane-associated protein 1

0.277

CD47_HUMAN

Leukocyte surface antigen CD47

0.277

SIAL_HUMAN

Bone sialoprotein 2

0.277

EGLN_HUMAN

Endoglin

0.277

MB214_HUMAN

Protein mab-21-like 4

0.277

SNTAN_HUMAN

Sentan

0.277

L37A1_HUMAN

Leucine-rich repeat-containing protein 37A

0.277

L37A2_HUMAN

Leucine-rich repeat-containing protein 37A2

0.277

PDZD9_HUMAN

PDZ domain-containing protein 9

0.277

A0A0G2JMZ2_HUMAN

Uncharacterized protein

0.277

IKZF3_HUMAN

Zinc finger protein Aiolos

0.365

CD6_HUMAN

T-cell differentiation antigen CD6

0.365

TNF15_HUMAN

Tumor necrosis factor ligand superfamily member 15

0.365

SPT16_HUMAN

Spermatogenesis-associated protein 16

0.365

CD28_HUMAN

T-cell-specific surface glycoprotein CD28

0.365

LAG3_HUMAN

Lymphocyte activation gene 3 protein

0.365

ZP2_HUMAN

Zona pellucida sperm-binding protein 2

0.365

ZBTB6_HUMAN

Zinc finger and BTB domain-containing protein 6

0.378

IFNK_HUMAN

Interferon kappa

0.378

LPAR5_HUMAN

Lysophosphatidic acid receptor 5

0.378

BCAS1_HUMAN

Breast carcinoma-amplified sequence 1

0.378

XKR2_HUMAN

XK-related protein 2

0.378

LAPM5_HUMAN

Lysosomal-associated transmembrane protein 5

0.378

TAF1D_HUMAN

TATA box-binding protein-associated factor RNA polymerase I subunit D

0.378

PRR36_HUMAN

Proline-rich protein 36

0.378

HMGN1_HUMAN

Non-histone chromosomal protein HMG-14

0.378

I13R1_HUMAN

Interleukin-13 receptor subunit alpha-1

0.378

MFAP5_HUMAN

Microfibrillar-associated protein 5

0.378

PROF3_HUMAN

Profilin-3

0.378

CC183_HUMAN

Coiled-coil domain-containing protein 183

0.378

CCD68_HUMAN

Coiled-coil domain-containing protein 68

0.378

INGR1_HUMAN

Interferon gamma receptor 1

0.378

CNCG_HUMAN

Retinal cone rhodopsin-sensitive cGMP 3,5-cyclic phosphodiesterase subunit gamma

0.378

CASPE_HUMAN

Caspase-14

0.378

IGSF1_HUMAN

Immunoglobulin superfamily member 1

0.378

AKAP8_HUMAN

A-kinase anchor protein 8

0.378

IRAK2_HUMAN

Interleukin-1 receptor-associated kinase-like 2

0.378

LNP1_HUMAN

Leukemia NUP98 fusion partner 1

0.378

IL22_HUMAN

Interleukin-22

0.378

INGR2_HUMAN

Interferon gamma receptor 2

0.378

ZN654_HUMAN

Zinc finger protein 654

0.378

NPS_HUMAN

Neuropeptide S

0.392

SHSA5_HUMAN

Protein shisa-5

0.392

LR37B_HUMAN

Leucine-rich repeat-containing protein 37B

0.392

CNTF_HUMAN

Ciliary neurotrophic factor

0.392

IGJ_HUMAN

Immunoglobulin J chain

0.392

CA094_HUMAN

Uncharacterized protein C1orf94

0.392

A1AG2_HUMAN

Alpha-1-acid glycoprotein 2

0.392

O52R1_HUMAN

Olfactory receptor 52R1

0.392

GSDMA_HUMAN

Gasdermin-A

0.392

FNDC9_HUMAN

Fibronectin type III domain-containing protein 9

0.392

BASP1_HUMAN

Brain acid soluble protein 1

0.392

NFAM1_HUMAN

NFAT activation molecule 1

0.392

LEP_HUMAN

Leptin

0.392

AKAP5_HUMAN

A-kinase anchor protein 5

0.392

K1C23_HUMAN

Keratin, type I cytoskeletal 23

0.392

UPKL2_HUMAN

Uroplakin-3b-like protein 2

0.392

OSTP_HUMAN

Osteopontin

0.392

VEXIN_HUMAN

Vexin

0.392

M4A15_HUMAN

Membrane-spanning 4-domains subfamily A member 15

0.392

MTCP1_HUMAN

Protein p13 MTCP-1

0.392

CO062_HUMAN

Uncharacterized protein C15orf62, mitochondrial

0.392

CD8B_HUMAN

T-cell surface glycoprotein CD8 beta chain

0.392

ZPBP2_HUMAN

Zona pellucida-binding protein 2

0.392

CC120_HUMAN

Coiled-coil domain-containing protein 120

0.392

IL15_HUMAN

Interleukin-15

0.392

TB182_HUMAN

182 kDa tankyrase-1-binding protein

0.392

GKN2_HUMAN

Gastrokine-2

0.392

PML_HUMAN

Protein PML

0.392

CD5_HUMAN

T-cell surface glycoprotein CD5

0.392

SPERT_HUMAN

Spermatid-associated protein

0.392

TNFL8_HUMAN

Tumor necrosis factor ligand superfamily member 8

0.392

MUC16_HUMAN

Mucin-16

0.392

TM109_HUMAN

Transmembrane protein 109

0.392

ZPBP1_HUMAN

Zona pellucida-binding protein 1

0.392

CD8B2_HUMAN

Putative T-cell surface glycoprotein CD8 beta-2 chain

0.392

MROH7_HUMAN

Maestro heat-like repeat-containing protein family member 7

0.392

FYB2_HUMAN

FYN-binding protein 2

0.392

MISSL_HUMAN

MAPK-interacting and spindle-stabilizing protein-like

0.392

CF132_HUMAN

Uncharacterized protein C6orf132

0.392

TSN32_HUMAN

Tetraspanin-32

0.392

IL9R_HUMAN

Interleukin-9 receptor

0.392

CD4_HUMAN

T-cell surface glycoprotein CD4

0.392

PSYR_HUMAN

Psychosine receptor

0.392

IL23R_HUMAN

Interleukin-23 receptor

0.392

CC185_HUMAN

Coiled-coil domain-containing protein 185

0.392

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

LAPM5_HUMAN

Lysosomal-associated transmembrane protein 5

0.378

LRAD1_HUMAN

Low-density lipoprotein receptor class A domain-containing protein 1

0.380

ICOSL_HUMAN

ICOS ligand

0.380

GSG1_HUMAN

Germ cell-specific gene 1 protein

0.392

MFAP5_HUMAN

Microfibrillar-associated protein 5

0.395

IL22_HUMAN

Interleukin-22

0.395

TREM2_HUMAN

Triggering receptor expressed on myeloid cells 2

0.395

SPERT_HUMAN

Spermatid-associated protein

0.397

LSME1_HUMAN

Leucine-rich single-pass membrane protein 1

0.400

GKN2_HUMAN

Gastrokine-2

0.400

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 14 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy