ANTR2_HUMAN 2019

Gene Name ANTR2

Description Anthrax toxin receptor 2

Length 489

9606

Sequence

>sp|P58335|ANTR2_HUMAN Anthrax toxin receptor 2
MVAERSPARSPGSWLFPGLWLLVLSGPGGLLRAQEQPSCRRAFDLYFVLDKSGSVANNWIEIYNFVQQLAERFVSPEMRLSFIVFSSQATIILPLTGDRGKISKGLEDLKRVSPVGETYIHEGLKLANEQIQKAGGLKTSSIIIALTDGKLDGLVPSYAEKEAKISRSLGASVYCVGVLDFEQAQLERIADSKEQVFPVKGGFQALKGIINSILAQSCTEILELQPSSVCVGEEFQIVLSGRGFMLGSRNGSVLCTYTVNETYTTSVKPVSVQLNSMLCPAPILNKAGETLDVSVSFNGGKSVISGSLIVTATECSNGIAAIIVILVLLLLLGIGLMWWFWPLCCKVVIKDPPPPPAPAPKEEEEEPLPTKKWPTVDASYYGGRGVGGIKRMEVRWGDKGSTEEGARLEKAKNAVVKIPEETEEPIRPRPPRPKPTHQPPQTKWYTPIKGRLDALWALLRRQYDRVSLMRPQEGDEVCIWECIEKELTA

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

No protein with similar profile across the domains were found

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

TNR19_HUMAN

Tumor necrosis factor receptor superfamily member 19

0.305

TNIP1_HUMAN

TNFAIP3-interacting protein 1

0.359

K0355_HUMAN

Uncharacterized protein KIAA0355

0.359

HNMT_HUMAN

Histamine N-methyltransferase

0.362

SIMC1_HUMAN

SUMO-interacting motif-containing protein 1

0.362

FANCC_HUMAN

Fanconi anemia group C protein

0.364

ANTR1_HUMAN

Anthrax toxin receptor 1

0.364

DKK2_HUMAN

Dickkopf-related protein 2

0.364

CCD73_HUMAN

Coiled-coil domain-containing protein 73

0.366

CDCA2_HUMAN

Cell division cycle-associated protein 2

0.368

PEA15_HUMAN

Astrocytic phosphoprotein PEA-15

0.368

TECTB_HUMAN

Beta-tectorin

0.370

CTHR1_HUMAN

Collagen triple helix repeat-containing protein 1

0.372

CNMD_HUMAN

Leukocyte cell-derived chemotaxin 1

0.374

KTBL1_HUMAN

KATNB1-like protein 1

0.374

MTFR1_HUMAN

Mitochondrial fission regulator 1

0.374

PRDM2_HUMAN

PR domain zinc finger protein 2

0.376

TARSH_HUMAN

Target of Nesh-SH3

0.376

STC2_HUMAN

Stanniocalcin-2

0.378

KNL1_HUMAN

Kinetochore scaffold 1

0.378

GAK1B_HUMAN

Golgi-associated kinase 1B

0.378

CNTLN_HUMAN

Centlein

0.382

CFAI_HUMAN

Complement factor I

0.382

TNMD_HUMAN

Tenomodulin

0.382

F168A_HUMAN

Protein FAM168A

0.382

ZN148_HUMAN

Zinc finger protein 148

0.382

R7BP_HUMAN

Regulator of G-protein signaling 7-binding protein

0.382

GT2D1_HUMAN

General transcription factor II-I repeat domain-containing protein 1

0.382

EDNRA_HUMAN

Endothelin-1 receptor

0.382

AFAP1_HUMAN

Actin filament-associated protein 1

0.383

SMPX_HUMAN

Small muscular protein

0.384

UIMC1_HUMAN

BRCA1-A complex subunit RAP80

0.384

PECA1_HUMAN

Platelet endothelial cell adhesion molecule

0.384

AL5AP_HUMAN

Arachidonate 5-lipoxygenase-activating protein

0.384

PIT1_HUMAN

Pituitary-specific positive transcription factor 1

0.385

ASB7_HUMAN

Ankyrin repeat and SOCS box protein 7

0.387

MASP1_HUMAN

Mannan-binding lectin serine protease 1

0.387

RET4_HUMAN

Retinol-binding protein 4

0.387

MATR3_HUMAN

Matrin-3

0.387

TALD3_HUMAN

Protein TALPID3

0.387

HPLN1_HUMAN

Hyaluronan and proteoglycan link protein 1

0.387

PRLR_HUMAN

Prolactin receptor

0.389

AKAP6_HUMAN

A-kinase anchor protein 6

0.389

NET4_HUMAN

Netrin-4

0.389

TGFB3_HUMAN

Transforming growth factor beta-3 proprotein

0.389

STC1_HUMAN

Stanniocalcin-1

0.389

CD166_HUMAN

CD166 antigen

0.391

ZN142_HUMAN

Zinc finger protein 142

0.391

LR75A_HUMAN

Leucine-rich repeat-containing protein 75A

0.391

TPA_HUMAN

Tissue-type plasminogen activator

0.391

MACC1_HUMAN

Metastasis-associated in colon cancer protein 1

0.391

CCSE2_HUMAN

Serine-rich coiled-coil domain-containing protein 2

0.393

PRDM5_HUMAN

PR domain zinc finger protein 5

0.393

LEPR_HUMAN

Leptin receptor

0.393

DRAXI_HUMAN

Draxin

0.393

ANGT_HUMAN

Angiotensinogen

0.393

SKA3_HUMAN

Spindle and kinetochore-associated protein 3

0.393

HDX_HUMAN

Highly divergent homeobox

0.393

GPNMB_HUMAN

Transmembrane glycoprotein NMB

0.393

BFSP1_HUMAN

Filensin

0.393

PHAG1_HUMAN

Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

0.393

MUC18_HUMAN

Cell surface glycoprotein MUC18

0.393

GDNF_HUMAN

Glial cell line-derived neurotrophic factor

0.393

TANK_HUMAN

TRAF family member-associated NF-kappa-B activator

0.393

MBP_HUMAN

Myelin basic protein

0.393

CAD17_HUMAN

Cadherin-17

0.393

SMS_HUMAN

Somatostatin

0.393

SCG3_HUMAN

Secretogranin-3

0.393

LUZP1_HUMAN

Leucine zipper protein 1

0.393

MREG_HUMAN

Melanoregulin

0.393

LGI2_HUMAN

Leucine-rich repeat LGI family member 2

0.393

WIZ_HUMAN

Protein Wiz

0.395

PROK1_HUMAN

Prokineticin-1

0.395

IN35_HUMAN

Interferon-induced 35 kDa protein

0.395

ZBT46_HUMAN

Zinc finger and BTB domain-containing protein 46

0.395

CLCF1_HUMAN

Cardiotrophin-like cytokine factor 1

0.395

DCSTP_HUMAN

Dendritic cell-specific transmembrane protein

0.395

HRH2_HUMAN

Histamine H2 receptor

0.396

NXPE3_HUMAN

NXPE family member 3

0.396

LYVE1_HUMAN

Lymphatic vessel endothelial hyaluronic acid receptor 1

0.397

CPZIP_HUMAN

CapZ-interacting protein

0.397

OBF1_HUMAN

POU domain class 2-associating factor 1

0.397

PDYN_HUMAN

Proenkephalin-B

0.397

GEMI4_HUMAN

Gem-associated protein 4

0.398

PEAK1_HUMAN

Inactive tyrosine-protein kinase PEAK1

0.398

RAG1_HUMAN

V(D)J recombination-activating protein 1

0.398

SIA7E_HUMAN

Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5

0.398

NTF3_HUMAN

Neurotrophin-3

0.398

TOPZ1_HUMAN

Protein TOPAZ1

0.399

TGFB2_HUMAN

Transforming growth factor beta-2 proprotein

0.400

PRSR1_HUMAN

Proline and serine-rich protein 1

0.400

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 21 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy