IFM3_HUMAN 2019

Gene Name IFM3

Description Interferon-induced transmembrane protein 3

Length 133

9606

Sequence

>sp|Q01628|IFM3_HUMAN Interferon-induced transmembrane protein 3
MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTILLIVIPVLIFQAYG

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

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What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

ARMX3_HUMAN

Armadillo repeat-containing X-linked protein 3

0.333

IFM2_HUMAN

Interferon-induced transmembrane protein 2

0.333

TRI27_HUMAN

Zinc finger protein RFP

0.333

ANR26_HUMAN

Ankyrin repeat domain-containing protein 26

0.387

SMI19_HUMAN

Small integral membrane protein 19

0.387

BEND5_HUMAN

BEN domain-containing protein 5

0.387

GFRA2_HUMAN

GDNF family receptor alpha-2

0.387

UR2R_HUMAN

Urotensin-2 receptor

0.387

GP153_HUMAN

Probable G-protein coupled receptor 153

0.387

CJ088_HUMAN

Uncharacterized protein C10orf88

0.387

PKR1_HUMAN

Prokineticin receptor 1

0.387

K1671_HUMAN

Uncharacterized protein KIAA1671

0.397

CRBA2_HUMAN

Beta-crystallin A2

0.397

CCD30_HUMAN

Coiled-coil domain-containing protein 30

0.397

HIC2_HUMAN

Hypermethylated in cancer 2 protein

0.397

ZN319_HUMAN

Zinc finger protein 319

0.397

PAR2_HUMAN

Proteinase-activated receptor 2

0.397

HXC13_HUMAN

Homeobox protein Hox-C13

0.397

CYTL1_HUMAN

Cytokine-like protein 1

0.397

BTC_HUMAN

Probetacellulin

0.397

ZN513_HUMAN

Zinc finger protein 513

0.397

CAVN4_HUMAN

Caveolae-associated protein 4

0.397

P121A_HUMAN

Nuclear envelope pore membrane protein POM 121

0.397

CHP3_HUMAN

Calcineurin B homologous protein 3

0.397

BSPRY_HUMAN

B box and SPRY domain-containing protein

0.397

P3IP1_HUMAN

Phosphoinositide-3-kinase-interacting protein 1

0.397

CML1_HUMAN

Chemokine-like receptor 1

0.397

F222A_HUMAN

Protein FAM222A

0.397

BT1A1_HUMAN

Butyrophilin subfamily 1 member A1

0.397

MYP0_HUMAN

Myelin protein P0

0.397

EVPL_HUMAN

Envoplakin

0.397

CN028_HUMAN

Uncharacterized protein C14orf28

0.397

HXA13_HUMAN

Homeobox protein Hox-A13

0.397

CALC_HUMAN

Calcitonin

0.397

PCD19_HUMAN

Protocadherin-19

0.397

ZN438_HUMAN

Zinc finger protein 438

0.397

TMG4_HUMAN

Transmembrane gamma-carboxyglutamic acid protein 4

0.397

CPLX3_HUMAN

Complexin-3

0.397

DBND1_HUMAN

Dysbindin domain-containing protein 1

0.397

TM240_HUMAN

Transmembrane protein 240

0.397

MPZL1_HUMAN

Myelin protein zero-like protein 1

0.397

RN214_HUMAN

RING finger protein 214

0.397

HECA2_HUMAN

HEPACAM family member 2

0.397

FETUB_HUMAN

Fetuin-B

0.397

SE6L1_HUMAN

Seizure 6-like protein

0.397

SLIK2_HUMAN

SLIT and NTRK-like protein 2

0.397

K1C18_HUMAN

Keratin, type I cytoskeletal 18

0.397

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

CC117_HUMAN

Coiled-coil domain-containing protein 117

0.356

F168A_HUMAN

Protein FAM168A

0.365

ZN148_HUMAN

Zinc finger protein 148

0.365

AKA12_HUMAN

A-kinase anchor protein 12

0.365

ERRFI_HUMAN

ERBB receptor feedback inhibitor 1

0.365

CCD30_HUMAN

Coiled-coil domain-containing protein 30

0.365

RN214_HUMAN

RING finger protein 214

0.367

MFAP2_HUMAN

Microfibrillar-associated protein 2

0.371

CKLF3_HUMAN

CKLF-like MARVEL transmembrane domain-containing protein 3

0.378

FMOD_HUMAN

Fibromodulin

0.378

SKA3_HUMAN

Spindle and kinetochore-associated protein 3

0.378

PRDM5_HUMAN

PR domain zinc finger protein 5

0.378

PHAG1_HUMAN

Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

0.378

SMS_HUMAN

Somatostatin

0.378

ZN335_HUMAN

Zinc finger protein 335

0.378

CLD11_HUMAN

Claudin-11

0.378

CCSE2_HUMAN

Serine-rich coiled-coil domain-containing protein 2

0.378

ANGT_HUMAN

Angiotensinogen

0.378

CXD2_HUMAN

Gap junction delta-2 protein

0.378

PALMD_HUMAN

Palmdelphin

0.378

CCR7_HUMAN

C-C chemokine receptor type 7

0.378

APJ_HUMAN

Apelin receptor

0.380

CCKN_HUMAN

Cholecystokinin

0.380

SYNCI_HUMAN

Syncoilin

0.380

IN35_HUMAN

Interferon-induced 35 kDa protein

0.380

DSG2_HUMAN

Desmoglein-2

0.380

CAVN4_HUMAN

Caveolae-associated protein 4

0.380

SE6L1_HUMAN

Seizure 6-like protein

0.380

PRSR2_HUMAN

Proline and serine-rich protein 2

0.382

TM108_HUMAN

Transmembrane protein 108

0.382

PDYN_HUMAN

Proenkephalin-B

0.382

CX021_HUMAN

Uncharacterized protein CXorf21

0.382

GEMC1_HUMAN

Geminin coiled-coil domain-containing protein 1

0.382

BTC_HUMAN

Probetacellulin

0.382

PCD12_HUMAN

Protocadherin-12

0.382

MAVS_HUMAN

Mitochondrial antiviral-signaling protein

0.387

CO039_HUMAN

Uncharacterized protein C15orf39

0.387

P33MX_HUMAN

Putative monooxygenase p33MONOX

0.390

LEG1_HUMAN

Galectin-1

0.390

CRBB1_HUMAN

Beta-crystallin B1

0.390

PCD19_HUMAN

Protocadherin-19

0.390

PDGFC_HUMAN

Platelet-derived growth factor C

0.390

VSTM4_HUMAN

V-set and transmembrane domain-containing protein 4

0.390

ZN644_HUMAN

Zinc finger protein 644

0.390

ZPLD1_HUMAN

Zona pellucida-like domain-containing protein 1

0.390

ADNP_HUMAN

Activity-dependent neuroprotector homeobox protein

0.390

NPY_HUMAN

Pro-neuropeptide Y

0.390

MERB1_HUMAN

bMERB domain-containing protein 1

0.390

PRL_HUMAN

Prolactin

0.390

STYK1_HUMAN

Tyrosine-protein kinase STYK1

0.390

MYZAP_HUMAN

Myocardial zonula adherens protein

0.390

GHR_HUMAN

Growth hormone receptor

0.390

OCLN_HUMAN

Occludin

0.390

ZN131_HUMAN

Zinc finger protein 131

0.390

EPYC_HUMAN

Epiphycan

0.390

SYBU_HUMAN

Syntabulin

0.390

PENK_HUMAN

Proenkephalin-A

0.390

NEXMI_HUMAN

Neurite extension and migration factor

0.390

MFA3L_HUMAN

Microfibrillar-associated protein 3-like

0.390

FETUB_HUMAN

Fetuin-B

0.392

SUSD1_HUMAN

Sushi domain-containing protein 1

0.392

SARG_HUMAN

Specifically androgen-regulated gene protein

0.392

JCAD_HUMAN

Junctional protein associated with coronary artery disease

0.392

SLIK1_HUMAN

SLIT and NTRK-like protein 1

0.392

CC126_HUMAN

Coiled-coil domain-containing protein 126

0.392

TNMD_HUMAN

Tenomodulin

0.392

ACKR3_HUMAN

Atypical chemokine receptor 3

0.392

BSPRY_HUMAN

B box and SPRY domain-containing protein

0.392

MRAP2_HUMAN

Melanocortin-2 receptor accessory protein 2

0.392

SYNEM_HUMAN

Synemin

0.392

CMGA_HUMAN

Chromogranin-A

0.392

FNDC7_HUMAN

Fibronectin type III domain-containing protein 7

0.392

EVPL_HUMAN

Envoplakin

0.392

F168B_HUMAN

Myelin-associated neurite-outgrowth inhibitor

0.392

ZN652_HUMAN

Zinc finger protein 652

0.392

GPC5C_HUMAN

G-protein coupled receptor family C group 5 member C

0.392

PEPL_HUMAN

Periplakin

0.392

CAVN2_HUMAN

Caveolae-associated protein 2

0.392

TSN1_HUMAN

Tetraspanin-1

0.392

OLFM4_HUMAN

Olfactomedin-4

0.392

PRELP_HUMAN

Prolargin

0.392

GDF9_HUMAN

Growth/differentiation factor 9

0.392

ZBT20_HUMAN

Zinc finger and BTB domain-containing protein 20

0.392

NUFP2_HUMAN

Nuclear fragile X mental retardation-interacting protein 2

0.392

F222B_HUMAN

Protein FAM222B

0.392

ZN513_HUMAN

Zinc finger protein 513

0.394

CHP3_HUMAN

Calcineurin B homologous protein 3

0.394

MYBPH_HUMAN

Myosin-binding protein H

0.394

DACT1_HUMAN

Dapper homolog 1

0.394

NEUM_HUMAN

Neuromodulin

0.394

AKAP2_HUMAN

A-kinase anchor protein 2

0.394

NOBOX_HUMAN

Homeobox protein NOBOX

0.397

SEZ6_HUMAN

Seizure protein 6 homolog

0.397

CYTL1_HUMAN

Cytokine-like protein 1

0.397

P2Y10_HUMAN

Putative P2Y purinoceptor 10

0.397

MDFI_HUMAN

MyoD family inhibitor

0.397

CTLA4_HUMAN

Cytotoxic T-lymphocyte protein 4

0.397

BMF_HUMAN

Bcl-2-modifying factor

0.397

BRID5_HUMAN

BRICHOS domain-containing protein 5

0.399

CYYR1_HUMAN

Cysteine and tyrosine-rich protein 1

0.399

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 17 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy