SATB1_HUMAN 2019

Gene Name SATB1

Description DNA-binding protein SATB1

Length 763

9606

Sequence

>sp|Q01826|SATB1_HUMAN DNA-binding protein SATB1
MDHLNEATQGKEHSEMSNNVSDPKGPPAKIARLEQNGSPLGRGRLGSTGAKMQGVPLKHSGHLMKTNLRKGTMLPVFCVVEHYENAIEYDCKEEHAEFVLVRKDMLFNQLIEMALLSLGYSHSSAAQAKGLIQVGKWNPVPLSYVTDAPDATVADMLQDVYHVVTLKIQLHSCPKLEDLPPEQWSHTTVRNALKDLLKDMNQSSLAKECPLSQSMISSIVNSTYYANVSAAKCQEFGRWYKHFKKTKDMMVEMDSLSELSQQGANHVNFGQQPVPGNTAEQPPSPAQLSHGSQPSVRTPLPNLHPGLVSTPISPQLVNQQLVMAQLLNQQYAVNRLLAQQSLNQQYLNHPPPVSRSMNKPLEQQVSTNTEVSSEIYQWVRDELKRAGISQAVFARVAFNRTQGLLSEILRKEEDPKTASQSLLVNLRAMQNFLQLPEAERDRIYQDERERSLNAASAMGPAPLISTPPSRPPQVKTATIATERNGKPENNTMNINASIYDEIQQEMKRAKVSQALFAKVAATKSQGWLCELLRWKEDPSPENRTLWENLSMIRRFLSLPQPERDAIYEQESNAVHHHGDRPPHIIHVPAEQIQQQQQQQQQQQQQQQAPPPPQPQQQPQTGPRLPPRQPTVASPAESDEENRQKTRPRTKISVEALGILQSFIQDVGLYPDEEAIQTLSAQLDLPKYTIIKFFQNQRYYLKHHGKLKDNSGLEVDVAEYKEEELLKDLEESVQDKNTNTLFSVKLEEELSVEGNTDINTDLKD

Domains

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Help

What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

SATB2_HUMAN

DNA-binding protein SATB2

0.162

RM51_HUMAN

39S ribosomal protein L51, mitochondrial

0.224

GNRHR_HUMAN

Gonadotropin-releasing hormone receptor

0.224

TMCC3_HUMAN

Transmembrane and coiled-coil domain protein 3

0.271

TMCC2_HUMAN

Transmembrane and coiled-coil domains protein 2

0.274

ALK_HUMAN

ALK tyrosine kinase receptor

0.274

SGCE_HUMAN

Epsilon-sarcoglycan

0.277

LEG8_HUMAN

Galectin-8

0.312

CTNL1_HUMAN

Alpha-catulin

0.312

TMCC1_HUMAN

Transmembrane and coiled-coil domains protein 1

0.312

NEO1_HUMAN

Neogenin

0.312

T22D2_HUMAN

TSC22 domain family protein 2

0.316

FA20C_HUMAN

Extracellular serine/threonine protein kinase FAM20C

0.316

CALRL_HUMAN

Calcitonin gene-related peptide type 1 receptor

0.316

MTP_HUMAN

Microsomal triglyceride transfer protein large subunit

0.316

DCC_HUMAN

Netrin receptor DCC

0.316

RB40B_HUMAN

Ras-related protein Rab-40B

0.324

ZEB2_HUMAN

Zinc finger E-box-binding homeobox 2

0.341

NDUB5_HUMAN

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial

0.341

MYO9A_HUMAN

Unconventional myosin-IXa

0.345

MBTD1_HUMAN

MBT domain-containing protein 1

0.345

BIG3_HUMAN

Brefeldin A-inhibited guanine nucleotide-exchange protein 3

0.345

NEGR1_HUMAN

Neuronal growth regulator 1

0.345

SYT4_HUMAN

Synaptotagmin-4

0.345

SBK1_HUMAN

Serine/threonine-protein kinase SBK1

0.349

STAU2_HUMAN

Double-stranded RNA-binding protein Staufen homolog 2

0.349

FA43A_HUMAN

Protein FAM43A

0.354

TWSG1_HUMAN

Twisted gastrulation protein homolog 1

0.354

SPRE2_HUMAN

Sprouty-related, EVH1 domain-containing protein 2

0.354

FER3L_HUMAN

Fer3-like protein

0.354

TICN2_HUMAN

Testican-2

0.354

FA43B_HUMAN

Protein FAM43B

0.354

T132E_HUMAN

Transmembrane protein 132E

0.358

SESD1_HUMAN

SEC14 domain and spectrin repeat-containing protein 1

0.358

BAG2_HUMAN

BAG family molecular chaperone regulator 2

0.358

GRPR_HUMAN

Gastrin-releasing peptide receptor

0.358

CCG5_HUMAN

Voltage-dependent calcium channel gamma-5 subunit

0.358

RB40C_HUMAN

Ras-related protein Rab-40C

0.363

ZEB1_HUMAN

Zinc finger E-box-binding homeobox 1

0.369

RT31_HUMAN

28S ribosomal protein S31, mitochondrial

0.369

NDUBA_HUMAN

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10

0.369

NR2C1_HUMAN

Nuclear receptor subfamily 2 group C member 1

0.374

CRYA2_HUMAN

Alpha-crystallin A2 chain

0.374

HME2_HUMAN

Homeobox protein engrailed-2

0.374

IKKE_HUMAN

Inhibitor of nuclear factor kappa-B kinase subunit epsilon

0.374

GRASP_HUMAN

General receptor for phosphoinositides 1-associated scaffold protein

0.374

HAND2_HUMAN

Heart- and neural crest derivatives-expressed protein 2

0.374

STAU1_HUMAN

Double-stranded RNA-binding protein Staufen homolog 1

0.378

TULP4_HUMAN

Tubby-related protein 4

0.378

SALL1_HUMAN

Sal-like protein 1

0.378

EFNB1_HUMAN

Ephrin-B1

0.378

PRD16_HUMAN

Histone-lysine N-methyltransferase PRDM16

0.378

GDF11_HUMAN

Growth/differentiation factor 11

0.378

VSX2_HUMAN

Visual system homeobox 2

0.378

MPRIP_HUMAN

Myosin phosphatase Rho-interacting protein

0.378

MYO9B_HUMAN

Unconventional myosin-IXb

0.378

AMOT_HUMAN

Angiomotin

0.378

SPDEF_HUMAN

SAM pointed domain-containing Ets transcription factor

0.378

AMOL2_HUMAN

Angiomotin-like protein 2

0.378

EFNB2_HUMAN

Ephrin-B2

0.378

TM10C_HUMAN

tRNA methyltransferase 10 homolog C

0.383

TUTLB_HUMAN

Protein turtle homolog B

0.383

SPIR2_HUMAN

Protein spire homolog 2

0.383

NPAS4_HUMAN

Neuronal PAS domain-containing protein 4

0.383

SGCB_HUMAN

Beta-sarcoglycan

0.383

STOX2_HUMAN

Storkhead-box protein 2

0.387

MED29_HUMAN

Mediator of RNA polymerase II transcription subunit 29

0.387

INHBA_HUMAN

Inhibin beta A chain

0.387

FA20A_HUMAN

Pseudokinase FAM20A

0.387

TMED6_HUMAN

Transmembrane emp24 domain-containing protein 6

0.387

NMUR1_HUMAN

Neuromedin-U receptor 1

0.387

SSR5_HUMAN

Somatostatin receptor type 5

0.387

SPRE1_HUMAN

Sprouty-related, EVH1 domain-containing protein 1

0.387

NMBR_HUMAN

Neuromedin-B receptor

0.392

PRDM8_HUMAN

PR domain zinc finger protein 8

0.392

NR2C2_HUMAN

Nuclear receptor subfamily 2 group C member 2

0.394

DACH2_HUMAN

Dachshund homolog 2

0.394

CD5R1_HUMAN

Cyclin-dependent kinase 5 activator 1

0.394

DACH1_HUMAN

Dachshund homolog 1

0.394

BTBD7_HUMAN

BTB/POZ domain-containing protein 7

0.394

HDC_HUMAN

Headcase protein homolog

0.394

CSTN1_HUMAN

Calsyntenin-1

0.394

FBX42_HUMAN

F-box only protein 42

0.399

FEZF1_HUMAN

Fez family zinc finger protein 1

0.399

PAR3L_HUMAN

Partitioning defective 3 homolog B

0.399

RAB30_HUMAN

Ras-related protein Rab-30

0.399

NID1_HUMAN

Nidogen-1

0.399

DIRA2_HUMAN

GTP-binding protein Di-Ras2

0.399

NFIL3_HUMAN

Nuclear factor interleukin-3-regulated protein

0.399

ACM2_HUMAN

Muscarinic acetylcholine receptor M2

0.399

SYDE2_HUMAN

Rho GTPase-activating protein SYDE2

0.399

CASC3_HUMAN

Protein CASC3

0.399

ACM3_HUMAN

Muscarinic acetylcholine receptor M3

0.399

CEBPG_HUMAN

CCAAT/enhancer-binding protein gamma

0.399

SKIL_HUMAN

Ski-like protein

0.399

S12A8_HUMAN

Solute carrier family 12 member 8

0.399

DLL1_HUMAN

Delta-like protein 1

0.399

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

SATB2_HUMAN

DNA-binding protein SATB2

0.191

RM51_HUMAN

39S ribosomal protein L51, mitochondrial

0.383

TMCC1_HUMAN

Transmembrane and coiled-coil domains protein 1

0.387

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 37 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy