ZN362_HUMAN 2019

Gene Name ZN362

Description Zinc finger protein 362

Length 420

9606

Sequence

>sp|Q5T0B9|ZN362_HUMAN Zinc finger protein 362
MSRSSPSGKGHSRMAEPRFNNPYFWPPPPTMPSQLDNLVLINKIKEQLMAEKIRPPHLPPTSASSQQPLLVPPAPAESSQAVMSLPKLQQVPGLHPQAVPQPDVALHARPATSTVTGLGLSTRTPSVSTSESSAGAGTGTGTSTPSTPTTTSQSRLIASSPTLISGITSPPLLDSIKTIQGHGLLGPPKSERGRKKIKAENPGGPPVLVVPYPILASGETAKEGKTYRCKVCPLTFFTKSEMQIHSKSHTEAKPHKCPHCSKSFANASYLAQHLRIHLGVKPYHCSYCDKSFRQLSHLQQHTRIHTGDRPYKCPHPGCEKAFTQLSNLQSHQRQHNKDKPYKCPNCYRAYSDSASLQIHLSAHAIKHAKAYCCSMCGRAYTSETYLMKHMSKHTVVEHLVSHHSPQRTESPGIPVRISLI

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

PRDM1_HUMAN

PR domain zinc finger protein 1

0.333

ZEB1_HUMAN

Zinc finger E-box-binding homeobox 1

0.361

LEG8_HUMAN

Galectin-8

0.369

DACH1_HUMAN

Dachshund homolog 1

0.386

CSTN1_HUMAN

Calsyntenin-1

0.386

NR2C2_HUMAN

Nuclear receptor subfamily 2 group C member 2

0.386

DACH2_HUMAN

Dachshund homolog 2

0.386

UNC5D_HUMAN

Netrin receptor UNC5D

0.390

NDUB5_HUMAN

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial

0.390

SALL4_HUMAN

Sal-like protein 4

0.390

ACM2_HUMAN

Muscarinic acetylcholine receptor M2

0.390

ACM3_HUMAN

Muscarinic acetylcholine receptor M3

0.390

ZEB2_HUMAN

Zinc finger E-box-binding homeobox 2

0.390

DIRA2_HUMAN

GTP-binding protein Di-Ras2

0.390

UNC5C_HUMAN

Netrin receptor UNC5C

0.390

NPHN_HUMAN

Nephrin

0.394

RM39_HUMAN

39S ribosomal protein L39, mitochondrial

0.394

SYT4_HUMAN

Synaptotagmin-4

0.394

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

LEG8_HUMAN

Galectin-8

0.337

SC5A8_HUMAN

Sodium-coupled monocarboxylate transporter 1

0.345

FA20C_HUMAN

Extracellular serine/threonine protein kinase FAM20C

0.353

KIRR1_HUMAN

Kin of IRRE-like protein 1

0.358

ALK_HUMAN

ALK tyrosine kinase receptor

0.362

KIRR3_HUMAN

Kin of IRRE-like protein 3

0.362

PRDM1_HUMAN

PR domain zinc finger protein 1

0.363

BCL7B_HUMAN

B-cell CLL/lymphoma 7 protein family member B

0.367

CSTN1_HUMAN

Calsyntenin-1

0.367

RORB_HUMAN

Nuclear receptor ROR-beta

0.367

UNC5D_HUMAN

Netrin receptor UNC5D

0.367

SALL1_HUMAN

Sal-like protein 1

0.369

AKAP1_HUMAN

A-kinase anchor protein 1, mitochondrial

0.369

ERBB2_HUMAN

Receptor tyrosine-protein kinase erbB-2

0.370

SARM1_HUMAN

Sterile alpha and TIR motif-containing protein 1

0.372

TEF_HUMAN

Thyrotroph embryonic factor

0.372

NR5A2_HUMAN

Nuclear receptor subfamily 5 group A member 2

0.373

5HT1B_HUMAN

5-hydroxytryptamine receptor 1B

0.374

ERBB4_HUMAN

Receptor tyrosine-protein kinase erbB-4

0.375

ZSWM8_HUMAN

Zinc finger SWIM domain-containing protein 8

0.375

CSPG4_HUMAN

Chondroitin sulfate proteoglycan 4

0.375

SAV1_HUMAN

Protein salvador homolog 1

0.375

5HT1A_HUMAN

5-hydroxytryptamine receptor 1A

0.375

ZEB1_HUMAN

Zinc finger E-box-binding homeobox 1

0.376

BNC2_HUMAN

Zinc finger protein basonuclin-2

0.377

ZEB2_HUMAN

Zinc finger E-box-binding homeobox 2

0.377

WLS_HUMAN

Protein wntless homolog

0.377

P85A_HUMAN

Phosphatidylinositol 3-kinase regulatory subunit alpha

0.377

UNC79_HUMAN

Protein unc-79 homolog

0.379

E41L5_HUMAN

Band 4.1-like protein 5

0.380

PROX1_HUMAN

Prospero homeobox protein 1

0.380

ROR1_HUMAN

Inactive tyrosine-protein kinase transmembrane receptor ROR1

0.380

CALRL_HUMAN

Calcitonin gene-related peptide type 1 receptor

0.380

NRCAM_HUMAN

Neuronal cell adhesion molecule

0.381

SEM6D_HUMAN

Semaphorin-6D

0.381

NDUB5_HUMAN

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial

0.382

UNC5C_HUMAN

Netrin receptor UNC5C

0.382

HINFP_HUMAN

Histone H4 transcription factor

0.383

AT1B1_HUMAN

Sodium/potassium-transporting ATPase subunit beta-1

0.383

AT1B4_HUMAN

Protein ATP1B4

0.383

ACM5_HUMAN

Muscarinic acetylcholine receptor M5

0.383

DAB2_HUMAN

Disabled homolog 2

0.383

APBA1_HUMAN

Amyloid-beta A4 precursor protein-binding family A member 1

0.383

ZN384_HUMAN

Zinc finger protein 384

0.384

RUND1_HUMAN

RUN domain-containing protein 1

0.384

RM39_HUMAN

39S ribosomal protein L39, mitochondrial

0.385

CYLD_HUMAN

Ubiquitin carboxyl-terminal hydrolase CYLD

0.385

ITB1_HUMAN

Integrin beta-1

0.386

HNF6_HUMAN

Hepatocyte nuclear factor 6

0.386

TNNI1_HUMAN

Troponin I, slow skeletal muscle

0.387

SPRC_HUMAN

SPARC

0.387

TSHR_HUMAN

Thyrotropin receptor

0.387

FBX25_HUMAN

F-box only protein 25

0.387

NFASC_HUMAN

Neurofascin

0.387

DAB1_HUMAN

Disabled homolog 1

0.387

TPD54_HUMAN

Tumor protein D54

0.387

T22D2_HUMAN

TSC22 domain family protein 2

0.388

DVL3_HUMAN

Segment polarity protein dishevelled homolog DVL-3

0.388

EGFR_HUMAN

Epidermal growth factor receptor

0.388

SUSD2_HUMAN

Sushi domain-containing protein 2

0.388

SYDE2_HUMAN

Rho GTPase-activating protein SYDE2

0.388

ACM2_HUMAN

Muscarinic acetylcholine receptor M2

0.388

NAB1_HUMAN

NGFI-A-binding protein 1

0.388

DOXA2_HUMAN

Dual oxidase maturation factor 2

0.388

T22D1_HUMAN

TSC22 domain family protein 1

0.389

APBA2_HUMAN

Amyloid-beta A4 precursor protein-binding family A member 2

0.389

TRIO_HUMAN

Triple functional domain protein

0.389

OFUT1_HUMAN

GDP-fucose protein O-fucosyltransferase 1

0.389

FERM2_HUMAN

Fermitin family homolog 2

0.389

TM38A_HUMAN

Trimeric intracellular cation channel type A

0.389

FERM1_HUMAN

Fermitin family homolog 1

0.389

TPD53_HUMAN

Tumor protein D53

0.389

HLF_HUMAN

Hepatic leukemia factor

0.390

TPST1_HUMAN

Protein-tyrosine sulfotransferase 1

0.390

MADD_HUMAN

MAP kinase-activating death domain protein

0.390

NEO1_HUMAN

Neogenin

0.390

ACHA7_HUMAN

Neuronal acetylcholine receptor subunit alpha-7

0.391

RIPL1_HUMAN

RILP-like protein 1

0.391

LRRF2_HUMAN

Leucine-rich repeat flightless-interacting protein 2

0.391

SEM6A_HUMAN

Semaphorin-6A

0.391

ERBB3_HUMAN

Receptor tyrosine-protein kinase erbB-3

0.391

CTNL1_HUMAN

Alpha-catulin

0.391

ACK1_HUMAN

Activated CDC42 kinase 1

0.392

ERP44_HUMAN

Endoplasmic reticulum resident protein 44

0.392

MESD_HUMAN

LRP chaperone MESD

0.393

BMP2_HUMAN

Bone morphogenetic protein 2

0.393

RM51_HUMAN

39S ribosomal protein L51, mitochondrial

0.393

BAG2_HUMAN

BAG family molecular chaperone regulator 2

0.393

NDUBA_HUMAN

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10

0.394

FBSP1_HUMAN

F-box/SPRY domain-containing protein 1

0.394

RBCC1_HUMAN

RB1-inducible coiled-coil protein 1

0.394

BC11A_HUMAN

B-cell lymphoma/leukemia 11A

0.395

NUMB_HUMAN

Protein numb homolog

0.395

ILF2_HUMAN

Interleukin enhancer-binding factor 2

0.395

MED19_HUMAN

Mediator of RNA polymerase II transcription subunit 19

0.395

FOXO3_HUMAN

Forkhead box protein O3

0.395

GLCE_HUMAN

D-glucuronyl C5-epimerase

0.395

BARH2_HUMAN

BarH-like 2 homeobox protein

0.396

EPHA4_HUMAN

Ephrin type-A receptor 4

0.396

BICD1_HUMAN

Protein bicaudal D homolog 1

0.396

HTF4_HUMAN

Transcription factor 12

0.396

MPRIP_HUMAN

Myosin phosphatase Rho-interacting protein

0.397

OSR2_HUMAN

Protein odd-skipped-related 2

0.397

MACOI_HUMAN

Macoilin

0.397

RGAP1_HUMAN

Rac GTPase-activating protein 1

0.397

GNRHR_HUMAN

Gonadotropin-releasing hormone receptor

0.398

PO4F3_HUMAN

POU domain, class 4, transcription factor 3

0.398

BMP5_HUMAN

Bone morphogenetic protein 5

0.398

CUBN_HUMAN

Cubilin

0.398

ELF2_HUMAN

ETS-related transcription factor Elf-2

0.398

SMCE1_HUMAN

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

0.398

RM40_HUMAN

39S ribosomal protein L40, mitochondrial

0.399

BCL7A_HUMAN

B-cell CLL/lymphoma 7 protein family member A

0.399

CSTN3_HUMAN

Calsyntenin-3

0.399

CBL_HUMAN

E3 ubiquitin-protein ligase CBL

0.399

RORA_HUMAN

Nuclear receptor ROR-alpha

0.400

TMM47_HUMAN

Transmembrane protein 47

0.400

RT30_HUMAN

39S ribosomal protein S30, mitochondrial

0.400

JIP1_HUMAN

C-Jun-amino-terminal kinase-interacting protein 1

0.400

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 42 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy