ZN618_HUMAN 2019

Gene Name ZN618

Description Zinc finger protein 618

Length 954

9606

Sequence

>sp|Q5T7W0|ZN618_HUMAN Zinc finger protein 618
MNQPGGAAAPQADGASAAGRKSTASRERLKRSQKSTKVEGPEPVPAEASLSAEQGTMTEVKVKTELPDDYIQEVIWQGEAKEEKKAVSKDGTSDVPAEICVVIGGVRNQQTLDGKAPEGSPHGGSVRSRYSGTWIFDQALRYASGSYECGICGKKYKYYNCFQTHVRAHRDTEATSGEGASQSNNFRYTCDICGKKYKYYSCFQEHRDLHAVDVFSVEGAPENRADPFDQGVVATDEVKEEPPEPFQKIGPKTGNYTCEFCGKQYKYYTPYQEHVALHAPISTAPGWEPPDDPDTGSECSHPEVSPSPRFVAAKTQTNQSGKKAPASVVRCATLLHRTPPATQTQTFRTPNSGSPASKATAAESAFSRRVEGKAQNHFEETNSSSQNSSEPYTCGACGIQFQFYNNLLEHMQSHAADNENNIASNQSRSPPAVVEEKWKPQAQRNSANNTTTSGLTPNSMIPEKERQNIAERLLRVMCADLGALSVVSGKEFLKLAQTLVDSGARYGAFSVTEILGNFNTLALKHLPRMYNQVKVKVTCALGSNACLGIGVTCHSQSVGPDSCYILTAYQAEGNHIKSYVLGVKGADIRDSGDLVHHWVQNVLSEFVMSEIRTVYVTDCRVSTSAFSKAGMCLRCSACALNSVVQSVLSKRTLQARSMHEVIELLNVCEDLAGSTGLAKETFGSLEETSPPPCWNSVTDSLLLVHERYEQICEFYSRAKKMNLIQSLNKHLLSNLAAILTPVKQAVIELSNESQPTLQLVLPTYVRLEKLFTAKANDAGTVSKLCHLFLEALKENFKVHPAHKVAMILDPQQKLRPVPPYQHEEIIGKVCELINEVKESWAEEADFEPAAKKPRSAAVENPAAQEDDRLGKNEVYDYLQEPLFQATPDLFQYWSCVTQKHTKLAKLAFWLLAVPAVGARSGCVNMCEQALLIKRRRLLSPEDMNKLMFLKSNML

Domains

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Help

What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

OLFL3_HUMAN

Olfactomedin-like protein 3

0.361

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

ZBT18_HUMAN

Zinc finger and BTB domain-containing protein 18

0.355

VCAM1_HUMAN

Vascular cell adhesion protein 1

0.355

ZBTB1_HUMAN

Zinc finger and BTB domain-containing protein 1

0.355

RIC3_HUMAN

Protein RIC-3

0.365

EURL_HUMAN

Protein EURL homolog

0.365

ZN644_HUMAN

Zinc finger protein 644

0.367

GHR_HUMAN

Growth hormone receptor

0.367

LEG1_HUMAN

Galectin-1

0.367

MERB1_HUMAN

bMERB domain-containing protein 1

0.367

PENK_HUMAN

Proenkephalin-A

0.367

NEXMI_HUMAN

Neurite extension and migration factor

0.367

SYBU_HUMAN

Syntabulin

0.367

OCLN_HUMAN

Occludin

0.367

P33MX_HUMAN

Putative monooxygenase p33MONOX

0.367

ADNP_HUMAN

Activity-dependent neuroprotector homeobox protein

0.367

ZPLD1_HUMAN

Zona pellucida-like domain-containing protein 1

0.367

VSTM4_HUMAN

V-set and transmembrane domain-containing protein 4

0.367

ZN131_HUMAN

Zinc finger protein 131

0.367

PDGFC_HUMAN

Platelet-derived growth factor C

0.367

ZBT10_HUMAN

Zinc finger and BTB domain-containing protein 10

0.367

NPY_HUMAN

Pro-neuropeptide Y

0.367

MFA3L_HUMAN

Microfibrillar-associated protein 3-like

0.367

PRL_HUMAN

Prolactin

0.367

MYZAP_HUMAN

Myocardial zonula adherens protein

0.367

REST_HUMAN

RE1-silencing transcription factor

0.369

K1107_HUMAN

AP2-interacting clathrin-endocytosis protein

0.369

ZBT20_HUMAN

Zinc finger and BTB domain-containing protein 20

0.369

CCPG1_HUMAN

Cell cycle progression protein 1

0.369

OLFM4_HUMAN

Olfactomedin-4

0.369

SCF_HUMAN

Kit ligand

0.369

CCD80_HUMAN

Coiled-coil domain-containing protein 80

0.378

GCR_HUMAN

Glucocorticoid receptor

0.378

ZN142_HUMAN

Zinc finger protein 142

0.378

CEP55_HUMAN

Centrosomal protein of 55 kDa

0.378

CD166_HUMAN

CD166 antigen

0.378

PTHR_HUMAN

Parathyroid hormone-related protein

0.380

GDNF_HUMAN

Glial cell line-derived neurotrophic factor

0.380

TANK_HUMAN

TRAF family member-associated NF-kappa-B activator

0.380

PALMD_HUMAN

Palmdelphin

0.380

LUR1L_HUMAN

Leucine rich adaptor protein 1-like

0.380

SPIN1_HUMAN

Spindlin-1

0.380

F131B_HUMAN

Protein FAM131B

0.380

AKA11_HUMAN

A-kinase anchor protein 11

0.380

RAG2_HUMAN

V(D)J recombination-activating protein 2

0.380

TMM51_HUMAN

Transmembrane protein 51

0.380

ZP3_HUMAN

Zona pellucida sperm-binding protein 3

0.380

PRDM5_HUMAN

PR domain zinc finger protein 5

0.380

BFSP1_HUMAN

Filensin

0.380

EDAR_HUMAN

Tumor necrosis factor receptor superfamily member EDAR

0.380

ITGBL_HUMAN

Integrin beta-like protein 1

0.380

ZN276_HUMAN

Zinc finger protein 276

0.380

FMOD_HUMAN

Fibromodulin

0.380

CCSE2_HUMAN

Serine-rich coiled-coil domain-containing protein 2

0.380

MNAR1_HUMAN

Major intrinsically disordered Notch2-binding receptor 1

0.380

CKLF3_HUMAN

CKLF-like MARVEL transmembrane domain-containing protein 3

0.380

NLRX1_HUMAN

NLR family member X1

0.380

ZN335_HUMAN

Zinc finger protein 335

0.380

ZBT16_HUMAN

Zinc finger and BTB domain-containing protein 16

0.380

LUZP1_HUMAN

Leucine zipper protein 1

0.380

CXD2_HUMAN

Gap junction delta-2 protein

0.380

PHAG1_HUMAN

Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

0.380

TEFF1_HUMAN

Tomoregulin-1

0.380

SMS_HUMAN

Somatostatin

0.380

SKA3_HUMAN

Spindle and kinetochore-associated protein 3

0.380

TF_HUMAN

Tissue factor

0.380

ABEC2_HUMAN

C->U-editing enzyme APOBEC-2

0.380

NYAP2_HUMAN

Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2

0.380

NAIF1_HUMAN

Nuclear apoptosis-inducing factor 1

0.380

CDCP1_HUMAN

CUB domain-containing protein 1

0.380

F1711_HUMAN

Protein FAM171A1

0.380

CLD11_HUMAN

Claudin-11

0.380

CXCR4_HUMAN

C-X-C chemokine receptor type 4

0.380

CCR7_HUMAN

C-C chemokine receptor type 7

0.380

LGI1_HUMAN

Leucine-rich glioma-inactivated protein 1

0.380

ZBTB2_HUMAN

Zinc finger and BTB domain-containing protein 2

0.380

M3K8_HUMAN

Mitogen-activated protein kinase kinase kinase 8

0.380

ANGT_HUMAN

Angiotensinogen

0.380

LYRIC_HUMAN

Protein LYRIC

0.380

FPRP_HUMAN

Prostaglandin F2 receptor negative regulator

0.380

MBP_HUMAN

Myelin basic protein

0.380

LEPR_HUMAN

Leptin receptor

0.380

AZI2_HUMAN

5-azacytidine-induced protein 2

0.380

CAD17_HUMAN

Cadherin-17

0.380

IL12B_HUMAN

Interleukin-12 subunit beta

0.382

ZBT14_HUMAN

Zinc finger and BTB domain-containing protein 14

0.382

BFSP2_HUMAN

Phakinin

0.382

ZBT24_HUMAN

Zinc finger and BTB domain-containing protein 24

0.382

LBH_HUMAN

Protein LBH

0.382

MYOZ2_HUMAN

Myozenin-2

0.382

ZBT41_HUMAN

Zinc finger and BTB domain-containing protein 41

0.382

CXAR_HUMAN

Coxsackievirus and adenovirus receptor

0.389

ZBT44_HUMAN

Zinc finger and BTB domain-containing protein 44

0.389

STC2_HUMAN

Stanniocalcin-2

0.389

CCG1_HUMAN

Voltage-dependent calcium channel gamma-1 subunit

0.389

GAK1B_HUMAN

Golgi-associated kinase 1B

0.389

BORG2_HUMAN

Cdc42 effector protein 3

0.389

STXB6_HUMAN

Syntaxin-binding protein 6

0.389

LEGL_HUMAN

Galectin-related protein

0.389

NHSL1_HUMAN

NHS-like protein 1

0.390

EMP2_HUMAN

Epithelial membrane protein 2

0.390

CALD1_HUMAN

Caldesmon

0.390

LARGN_HUMAN

Protein Largen

0.390

EPYC_HUMAN

Epiphycan

0.390

FAKD2_HUMAN

FAST kinase domain-containing protein 2, mitochondrial

0.390

PXDC1_HUMAN

PX domain-containing protein 1

0.390

CFLAR_HUMAN

CASP8 and FADD-like apoptosis regulator

0.390

CIPC_HUMAN

CLOCK-interacting pacemaker

0.390

BEND7_HUMAN

BEN domain-containing protein 7

0.390

TM263_HUMAN

Transmembrane protein 263

0.390

PEDF_HUMAN

Pigment epithelium-derived factor

0.390

SGO1_HUMAN

Shugoshin 1

0.390

ZBT11_HUMAN

Zinc finger and BTB domain-containing protein 11

0.390

AGRF5_HUMAN

Adhesion G protein-coupled receptor F5

0.390

ASTN1_HUMAN

Astrotactin-1

0.390

CDHR1_HUMAN

Cadherin-related family member 1

0.390

CO8A_HUMAN

Complement component C8 alpha chain

0.390

PCD19_HUMAN

Protocadherin-19

0.390

MRAP2_HUMAN

Melanocortin-2 receptor accessory protein 2

0.392

SUSD6_HUMAN

Sushi domain-containing protein 6

0.392

SUSD1_HUMAN

Sushi domain-containing protein 1

0.392

SARG_HUMAN

Specifically androgen-regulated gene protein

0.392

F168A_HUMAN

Protein FAM168A

0.392

JCAD_HUMAN

Junctional protein associated with coronary artery disease

0.392

F163B_HUMAN

Protein FAM163B

0.392

CC126_HUMAN

Coiled-coil domain-containing protein 126

0.392

APOH_HUMAN

Beta-2-glycoprotein 1

0.392

AKA12_HUMAN

A-kinase anchor protein 12

0.392

FETUB_HUMAN

Fetuin-B

0.392

HECAM_HUMAN

Hepatocyte cell adhesion molecule

0.392

F180A_HUMAN

Protein FAM180A

0.392

ACKR3_HUMAN

Atypical chemokine receptor 3

0.392

R7BP_HUMAN

Regulator of G-protein signaling 7-binding protein

0.392

BSPRY_HUMAN

B box and SPRY domain-containing protein

0.392

ESAM_HUMAN

Endothelial cell-selective adhesion molecule

0.392

ERRFI_HUMAN

ERBB receptor feedback inhibitor 1

0.392

OLFL3_HUMAN

Olfactomedin-like protein 3

0.392

IKIP_HUMAN

Inhibitor of nuclear factor kappa-B kinase-interacting protein

0.392

HBEGF_HUMAN

Proheparin-binding EGF-like growth factor

0.392

SYNEM_HUMAN

Synemin

0.392

CMGA_HUMAN

Chromogranin-A

0.392

TR150_HUMAN

Thyroid hormone receptor-associated protein 3

0.392

FNDC7_HUMAN

Fibronectin type III domain-containing protein 7

0.392

GP176_HUMAN

G-protein coupled receptor 176

0.392

EVPL_HUMAN

Envoplakin

0.392

F168B_HUMAN

Myelin-associated neurite-outgrowth inhibitor

0.392

MIME_HUMAN

Mimecan

0.392

ZN652_HUMAN

Zinc finger protein 652

0.392

CFAI_HUMAN

Complement factor I

0.392

GPC5C_HUMAN

G-protein coupled receptor family C group 5 member C

0.392

TSG6_HUMAN

Tumor necrosis factor-inducible gene 6 protein

0.392

MFR1L_HUMAN

Mitochondrial fission regulator 1-like

0.392

GTF2I_HUMAN

General transcription factor II-I

0.392

PEPL_HUMAN

Periplakin

0.392

PGFRL_HUMAN

Platelet-derived growth factor receptor-like protein

0.392

TM182_HUMAN

Transmembrane protein 182

0.392

CAVN2_HUMAN

Caveolae-associated protein 2

0.392

TRH_HUMAN

Pro-thyrotropin-releasing hormone

0.392

XIRP2_HUMAN

Xin actin-binding repeat-containing protein 2

0.392

UIF_HUMAN

UAP56-interacting factor

0.392

TSN1_HUMAN

Tetraspanin-1

0.392

PRELP_HUMAN

Prolargin

0.392

GDF9_HUMAN

Growth/differentiation factor 9

0.392

SCN3B_HUMAN

Sodium channel subunit beta-3

0.392

MAL_HUMAN

Myelin and lymphocyte protein

0.392

NUFP2_HUMAN

Nuclear fragile X mental retardation-interacting protein 2

0.392

F222B_HUMAN

Protein FAM222B

0.392

F131A_HUMAN

Protein FAM131A

0.392

BAG5_HUMAN

BAG family molecular chaperone regulator 5

0.392

ZBT25_HUMAN

Zinc finger and BTB domain-containing protein 25

0.394

TCIM_HUMAN

Transcriptional and immune response regulator

0.394

RN214_HUMAN

RING finger protein 214

0.394

ICAL_HUMAN

Calpastatin

0.394

5HT5A_HUMAN

5-hydroxytryptamine receptor 5A

0.397

PRLR_HUMAN

Prolactin receptor

0.399

NEXN_HUMAN

Nexilin

0.399

P3IP1_HUMAN

Phosphoinositide-3-kinase-interacting protein 1

0.399

HG2A_HUMAN

HLA class II histocompatibility antigen gamma chain

0.399

NET4_HUMAN

Netrin-4

0.399

HMGX3_HUMAN

HMG domain-containing protein 3

0.399

STC1_HUMAN

Stanniocalcin-1

0.399

NECT1_HUMAN

Nectin-1

0.399

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 23 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy