RIPP2_HUMAN 2019

Gene Name RIPP2

Description Protein ripply2

Length 128

9606

Sequence

>sp|Q5TAB7|RIPP2_HUMAN Protein ripply2
MENAGGAEGTESGAAACAATDGPTRRAGADSGYAGFWRPWVDAGGKKEEETPNHAAEAMPDGPGMTAASGKLYQFRHPVRLFWPKSKCYDYLYQEAEALLKNFPIQATISFYEDSDSEDEIEDLTCEN

Domains

Loading...

Help

What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

TM116_HUMAN

Transmembrane protein 116

0.224

F1891_HUMAN

Protein FAM189A1

0.309

HMGX3_HUMAN

HMG domain-containing protein 3

0.309

LR14B_HUMAN

Leucine-rich repeat-containing protein 14B

0.309

VEGFC_HUMAN

Vascular endothelial growth factor C

0.309

HPLN1_HUMAN

Hyaluronan and proteoglycan link protein 1

0.309

RAMP1_HUMAN

Receptor activity-modifying protein 1

0.316

F241A_HUMAN

Uncharacterized protein FAM241A

0.316

K1549_HUMAN

UPF0606 protein KIAA1549

0.316

SHL2A_HUMAN

Protein shisa-like-2A

0.316

ADNP2_HUMAN

Activity-dependent neuroprotector homeobox protein 2

0.316

LRC8C_HUMAN

Volume-regulated anion channel subunit LRRC8C

0.316

KLD7A_HUMAN

Kelch domain-containing protein 7A

0.316

CTXN3_HUMAN

Cortexin-3

0.324

TMG3_HUMAN

Transmembrane gamma-carboxyglutamic acid protein 3

0.324

HNMT_HUMAN

Histamine N-methyltransferase

0.369

FADS6_HUMAN

Fatty acid desaturase 6

0.369

PKR2_HUMAN

Prokineticin receptor 2

0.369

MASP1_HUMAN

Mannan-binding lectin serine protease 1

0.369

PIT1_HUMAN

Pituitary-specific positive transcription factor 1

0.369

EURL_HUMAN

Protein EURL homolog

0.378

LGI1_HUMAN

Leucine-rich glioma-inactivated protein 1

0.378

CAHM1_HUMAN

Calcium homeostasis modulator protein 1

0.378

SCG3_HUMAN

Secretogranin-3

0.378

F181A_HUMAN

Protein FAM181A

0.378

CCDC3_HUMAN

Coiled-coil domain-containing protein 3

0.378

PEX26_HUMAN

Peroxisome assembly protein 26

0.378

TR19L_HUMAN

Tumor necrosis factor receptor superfamily member 19L

0.378

LGI2_HUMAN

Leucine-rich repeat LGI family member 2

0.378

PROK1_HUMAN

Prokineticin-1

0.378

EDAR_HUMAN

Tumor necrosis factor receptor superfamily member EDAR

0.378

GPR26_HUMAN

G-protein coupled receptor 26

0.378

PKR1_HUMAN

Prokineticin receptor 1

0.378

TSN18_HUMAN

Tetraspanin-18

0.378

EDNRB_HUMAN

Endothelin receptor type B

0.378

LARGN_HUMAN

Protein Largen

0.378

NYX_HUMAN

Nyctalopin

0.378

T255A_HUMAN

Transmembrane protein 255A

0.378

SCAR5_HUMAN

Scavenger receptor class A member 5

0.378

GPR19_HUMAN

Probable G-protein coupled receptor 19

0.378

HBAZ_HUMAN

Hemoglobin subunit zeta

0.378

MC4R_HUMAN

Melanocortin receptor 4

0.378

ZBT10_HUMAN

Zinc finger and BTB domain-containing protein 10

0.378

ZHX2_HUMAN

Zinc fingers and homeoboxes protein 2

0.378

LRAD3_HUMAN

Low-density lipoprotein receptor class A domain-containing protein 3

0.378

EDNRA_HUMAN

Endothelin-1 receptor

0.378

I10R2_HUMAN

Interleukin-10 receptor subunit beta

0.378

PGBD5_HUMAN

PiggyBac transposable element-derived protein 5

0.378

PTN_HUMAN

Pleiotrophin

0.378

ZN148_HUMAN

Zinc finger protein 148

0.378

TPA_HUMAN

Tissue-type plasminogen activator

0.378

PCLI1_HUMAN

PTB-containing, cubilin and LRP1-interacting protein

0.378

CRBA1_HUMAN

Beta-crystallin A3

0.378

GAK1B_HUMAN

Golgi-associated kinase 1B

0.378

THMS1_HUMAN

Protein THEMIS

0.378

RAMP3_HUMAN

Receptor activity-modifying protein 3

0.378

HPLN4_HUMAN

Hyaluronan and proteoglycan link protein 4

0.378

PRLHR_HUMAN

Prolactin-releasing peptide receptor

0.378

RFXAP_HUMAN

Regulatory factor X-associated protein

0.378

PRLR_HUMAN

Prolactin receptor

0.378

EFCC1_HUMAN

EF-hand and coiled-coil domain-containing protein 1

0.378

RLF_HUMAN

Zinc finger protein Rlf

0.378

C2C4C_HUMAN

C2 calcium-dependent domain-containing protein 4C

0.378

CXL14_HUMAN

C-X-C motif chemokine 14

0.387

FETUB_HUMAN

Fetuin-B

0.387

DSN1_HUMAN

Kinetochore-associated protein DSN1 homolog

0.387

TM240_HUMAN

Transmembrane protein 240

0.387

AKP8L_HUMAN

A-kinase anchor protein 8-like

0.387

ZN638_HUMAN

Zinc finger protein 638

0.387

SYT13_HUMAN

Synaptotagmin-13

0.387

CO039_HUMAN

Uncharacterized protein C15orf39

0.387

BTC_HUMAN

Probetacellulin

0.387

TMG4_HUMAN

Transmembrane gamma-carboxyglutamic acid protein 4

0.387

CHP3_HUMAN

Calcineurin B homologous protein 3

0.387

CRBA2_HUMAN

Beta-crystallin A2

0.387

CALC_HUMAN

Calcitonin

0.387

K1C18_HUMAN

Keratin, type I cytoskeletal 18

0.387

F1892_HUMAN

Protein FAM189A2

0.387

MPZL1_HUMAN

Myelin protein zero-like protein 1

0.387

RHBD2_HUMAN

Rhomboid domain-containing protein 2

0.387

HECA2_HUMAN

HEPACAM family member 2

0.387

SNN_HUMAN

Stannin

0.387

EVPL_HUMAN

Envoplakin

0.387

GAK1A_HUMAN

Golgi-associated kinase 1A

0.387

BT1A1_HUMAN

Butyrophilin subfamily 1 member A1

0.387

HXC13_HUMAN

Homeobox protein Hox-C13

0.387

K2C8_HUMAN

Keratin, type II cytoskeletal 8

0.387

C2TA_HUMAN

MHC class II transactivator

0.387

ZN319_HUMAN

Zinc finger protein 319

0.387

GLPC_HUMAN

Glycophorin-C

0.387

R51A1_HUMAN

RAD51-associated protein 1

0.387

JCAD_HUMAN

Junctional protein associated with coronary artery disease

0.387

SETBP_HUMAN

SET-binding protein

0.387

CML1_HUMAN

Chemokine-like receptor 1

0.387

AHDC1_HUMAN

AT-hook DNA-binding motif-containing protein 1

0.387

MRP_HUMAN

MARCKS-related protein

0.387

CU058_HUMAN

Uncharacterized protein C21orf58

0.397

IGSF5_HUMAN

Immunoglobulin superfamily member 5

0.397

PRRP_HUMAN

Prolactin-releasing peptide

0.397

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

RFXAP_HUMAN

Regulatory factor X-associated protein

0.378

ZN148_HUMAN

Zinc finger protein 148

0.388

HPLN1_HUMAN

Hyaluronan and proteoglycan link protein 1

0.393

MASP1_HUMAN

Mannan-binding lectin serine protease 1

0.393

LR75A_HUMAN

Leucine-rich repeat-containing protein 75A

0.397

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 19 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy