CAD24_HUMAN 2019

Gene Name CAD24

Description Cadherin-24

Length 819

9606

Sequence

>sp|Q86UP0|CAD24_HUMAN Cadherin-24
MWGLVRLLLAWLGGWGCMGRLAAPARAWAGSREHPGPALLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAADLDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVSFQGPLGPDANFTVQDNRDGSASLLLPSRPAPPRHAPYLVPIELWDWGQPALSSTATVTVSVCRCQPDGSVASCWPEAHLSAAGLSTGALLAIITCVGALLALVVLFVALRRQKQEALMVLEEEDVRENIITYDDEGGGEEDTEAFDITALQNPDGAAPPAPGPPARRDVLPRARVSRQPRPPGPADVAQLLALRLREADEDPGVPPYDSVQVYGYEGRGSSCGSLSSLGSGSEAGGAPGPAEPLDDWGPLFRTLAELYGAKEPPAP

Domains

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Help

What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

No protein with similar profile across the domains were found

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

ZNF18_HUMAN

Zinc finger protein 18

0.309

LAT_HUMAN

Linker for activation of T-cells family member 1

0.311

ZKSC5_HUMAN

Zinc finger protein with KRAB and SCAN domains 5

0.333

RAGE_HUMAN

Advanced glycosylation end product-specific receptor

0.333

F186B_HUMAN

Protein FAM186B

0.333

IL1A_HUMAN

Interleukin-1 alpha

0.333

CC116_HUMAN

Coiled-coil domain-containing protein 116

0.336

G6B_HUMAN

Megakaryocyte and platelet inhibitory receptor G6b

0.336

DBND2_HUMAN

Dysbindin domain-containing protein 2

0.336

NGAL_HUMAN

Neutrophil gelatinase-associated lipocalin

0.336

LAX1_HUMAN

Lymphocyte transmembrane adapter 1

0.354

SPAT9_HUMAN

Spermatogenesis-associated protein 9

0.354

PA2GF_HUMAN

Group IIF secretory phospholipase A2

0.354

ZN202_HUMAN

Zinc finger protein 202

0.354

DKKL1_HUMAN

Dickkopf-like protein 1

0.356

IL5_HUMAN

Interleukin-5

0.356

CD19_HUMAN

B-lymphocyte antigen CD19

0.356

PRS37_HUMAN

Probable inactive serine protease 37

0.356

O13C7_HUMAN

Olfactory receptor 13C7

0.356

IL2_HUMAN

Interleukin-2

0.356

CSF2_HUMAN

Granulocyte-macrophage colony-stimulating factor

0.356

TMCO2_HUMAN

Transmembrane and coiled-coil domain-containing protein 2

0.356

ZN496_HUMAN

Zinc finger protein 496

0.356

CKLF5_HUMAN

CKLF-like MARVEL transmembrane domain-containing protein 5

0.359

MASTR_HUMAN

MEF2-activating motif and SAP domain-containing transcriptional regulator

0.359

CLD9_HUMAN

Claudin-9

0.359

CDSN_HUMAN

Corneodesmosin

0.359

CC121_HUMAN

Coiled-coil domain-containing protein 121

0.372

GL6D1_HUMAN

Putative glycosyltransferase 6 domain-containing protein 1

0.372

GPC5D_HUMAN

G-protein coupled receptor family C group 5 member D

0.372

IL27A_HUMAN

Interleukin-27 subunit alpha

0.372

AKAP3_HUMAN

A-kinase anchor protein 3

0.372

SPNDC_HUMAN

Spindlin interactor and repressor of chromatin-binding protein

0.372

TSKS_HUMAN

Testis-specific serine kinase substrate

0.372

CQ080_HUMAN

Uncharacterized protein C17orf80

0.375

ZKSC2_HUMAN

Zinc finger protein with KRAB and SCAN domains 2

0.375

TM219_HUMAN

Insulin-like growth factor-binding protein 3 receptor

0.375

DMKN_HUMAN

Dermokine

0.375

S10A8_HUMAN

Protein S100-A8

0.375

CC196_HUMAN

Putative coiled-coil domain-containing protein 196

0.375

ZKSC1_HUMAN

Zinc finger protein with KRAB and SCAN domains 1

0.375

ZSC29_HUMAN

Zinc finger and SCAN domain-containing protein 29

0.375

KRBA1_HUMAN

Protein KRBA1

0.378

F170A_HUMAN

Protein FAM170A

0.378

ZFP1_HUMAN

Zinc finger protein 1 homolog

0.378

F229B_HUMAN

Protein FAM229B

0.378

TMC5A_HUMAN

Transmembrane and coiled-coil domain-containing protein 5A

0.378

CD70_HUMAN

CD70 antigen

0.378

LY66F_HUMAN

Lymphocyte antigen 6 complex locus protein G6f

0.378

ZN189_HUMAN

Zinc finger protein 189

0.378

CJ120_HUMAN

Uncharacterized protein C10orf120

0.378

TREM1_HUMAN

Triggering receptor expressed on myeloid cells 1

0.378

ZN449_HUMAN

Zinc finger protein 449

0.378

ZN200_HUMAN

Zinc finger protein 200

0.378

F205A_HUMAN

Protein FAM205A

0.378

ZN263_HUMAN

Zinc finger protein 263

0.378

OPALI_HUMAN

Opalin

0.378

PRCA1_HUMAN

Protein PROCA1

0.381

PRS58_HUMAN

Serine protease 58

0.381

LY6H_HUMAN

Lymphocyte antigen 6H

0.381

CD320_HUMAN

CD320 antigen

0.381

ZN446_HUMAN

Zinc finger protein 446

0.381

LY66C_HUMAN

Lymphocyte antigen 6 complex locus protein G6c

0.381

CK042_HUMAN

Uncharacterized protein C11orf42

0.386

T4S19_HUMAN

Transmembrane 4 L6 family member 19

0.389

FNDC8_HUMAN

Fibronectin type III domain-containing protein 8

0.389

T53G5_HUMAN

TP53-target gene 5 protein

0.389

PRIC4_HUMAN

Prickle-like protein 4

0.389

NKG7_HUMAN

Protein NKG7

0.392

NAR3_HUMAN

Ecto-ADP-ribosyltransferase 3

0.392

CBLN3_HUMAN

Cerebellin-3

0.392

IL24_HUMAN

Interleukin-24

0.392

ZSC20_HUMAN

Zinc finger and SCAN domain-containing protein 20

0.392

TRML1_HUMAN

Trem-like transcript 1 protein

0.392

ZN184_HUMAN

Zinc finger protein 184

0.395

OR2F1_HUMAN

Olfactory receptor 2F1

0.395

ZSC10_HUMAN

Zinc finger and SCAN domain-containing protein 10

0.395

MEFV_HUMAN

Pyrin

0.395

ZN691_HUMAN

Zinc finger protein 691

0.395

TNF18_HUMAN

Tumor necrosis factor ligand superfamily member 18

0.395

CCL22_HUMAN

C-C motif chemokine 22

0.395

BPIA1_HUMAN

BPI fold-containing family A member 1

0.395

BPIB1_HUMAN

BPI fold-containing family B member 1

0.395

ACTT3_HUMAN

Actin-related protein T3

0.395

CCR10_HUMAN

C-C chemokine receptor type 10

0.395

IL13_HUMAN

Interleukin-13

0.398

BEX3_HUMAN

Protein BEX3

0.398

ZNF48_HUMAN

Zinc finger protein 48

0.398

ETV2_HUMAN

ETS translocation variant 2

0.398

LY6D_HUMAN

Lymphocyte antigen 6D

0.398

BPIA3_HUMAN

BPI fold-containing family A member 3

0.398

PRR19_HUMAN

Proline-rich protein 19

0.398

CB074_HUMAN

Uncharacterized protein C2orf74

0.398

ODAM_HUMAN

Odontogenic ameloblast-associated protein

0.398

PKHH3_HUMAN

Pleckstrin homology domain-containing family H member 3

0.398

ZSC25_HUMAN

Zinc finger and SCAN domain-containing protein 25

0.398

MEPE_HUMAN

Matrix extracellular phosphoglycoprotein

0.398

IRGQ_HUMAN

Immunity-related GTPase family Q protein

0.398

TRIMM_HUMAN

Probable E3 ubiquitin-protein ligase TRIML2

0.398

IL36G_HUMAN

Interleukin-36 gamma

0.398

IL33_HUMAN

Interleukin-33

0.398

ZN174_HUMAN

Zinc finger protein 174

0.398

CAVN3_HUMAN

Caveolae-associated protein 3

0.398

ZN445_HUMAN

Zinc finger protein 445

0.398

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 11 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy