AMGO3_HUMAN 2019

Gene Name AMGO3

Description Amphoterin-induced protein 3

Length 504

9606

Sequence

>sp|Q86WK7|AMGO3_HUMAN Amphoterin-induced protein 3
MTWLVLLGTLLCMLRVGLGTPDSEGFPPRALHNCPYKCICAADLLSCTGLGLQDVPAELPAATADLDLSHNALQRLRPGWLAPLFQLRALHLDHNELDALGRGVFVNASGLRLLDLSSNTLRALGRHDLDGLGALEKLLLFNNRLVHLDEHAFHGLRALSHLYLGCNELASFSFDHLHGLSATHLLTLDLSSNRLGHISVPELAALPAFLKNGLYLHNNPLPCDCRLYHLLQRWHQRGLSAVRDFAREYVCLAFKVPASRVRFFQHSRVFENCSSAPALGLERPEEHLYALVGRSLRLYCNTSVPAMRIAWVSPQQELLRAPGSRDGSIAVLADGSLAIGNVQEQHAGLFVCLATGPRLHHNQTHEYNVSVHFPRPEPEAFNTGFTTLLGCAVGLVLVLLYLFAPPCRCCRRACRCRRWPQTPSPLQELSAQSSVLSTTPPDAPSRKASVHKHVVFLEPGRRGLNGRVQLAVAEEFDLYNPGGLQLKAGSESASSIGSEGPMTT

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

CMYA5_HUMAN

Cardiomyopathy-associated protein 5

0.333

CCD71_HUMAN

Coiled-coil domain-containing protein 71

0.333

NOL7_HUMAN

Nucleolar protein 7

0.333

GP146_HUMAN

Probable G-protein coupled receptor 146

0.333

CCR9_HUMAN

C-C chemokine receptor type 9

0.333

Z518A_HUMAN

Zinc finger protein 518A

0.333

CBARP_HUMAN

Voltage-dependent calcium channel beta subunit-associated regulatory protein

0.333

GP141_HUMAN

Probable G-protein coupled receptor 141

0.333

K1C13_HUMAN

Keratin, type I cytoskeletal 13

0.343

K1C15_HUMAN

Keratin, type I cytoskeletal 15

0.343

CD054_HUMAN

Uncharacterized protein C4orf54

0.343

CCR4_HUMAN

C-C chemokine receptor type 4

0.397

TMM71_HUMAN

Transmembrane protein 71

0.397

HBEGF_HUMAN

Proheparin-binding EGF-like growth factor

0.397

CLTR1_HUMAN

Cysteinyl leukotriene receptor 1

0.397

CLD12_HUMAN

Claudin-12

0.397

CC126_HUMAN

Coiled-coil domain-containing protein 126

0.397

TOR4A_HUMAN

Torsin-4A

0.397

GP174_HUMAN

Probable G-protein coupled receptor 174

0.397

ANGL3_HUMAN

Angiopoietin-related protein 3

0.397

CE030_HUMAN

UNC119-binding protein C5orf30

0.397

P2RY1_HUMAN

P2Y purinoceptor 1

0.397

PRR35_HUMAN

Proline-rich protein 35

0.397

DQA1_HUMAN

HLA class II histocompatibility antigen, DQ alpha 1 chain

0.397

LPAR4_HUMAN

Lysophosphatidic acid receptor 4

0.397

IL2RG_HUMAN

Cytokine receptor common subunit gamma

0.397

EMB_HUMAN

Embigin

0.397

SUSD5_HUMAN

Sushi domain-containing protein 5

0.397

CNRG_HUMAN

Retinal rod rhodopsin-sensitive cGMP 3,5-cyclic phosphodiesterase subunit gamma

0.397

TAFA4_HUMAN

Chemokine-like protein TAFA-4

0.397

ZBT38_HUMAN

Zinc finger and BTB domain-containing protein 38

0.397

F171B_HUMAN

Protein FAM171B

0.397

NRN1_HUMAN

Neuritin

0.397

GALA_HUMAN

Galanin peptides

0.397

NIBAN_HUMAN

Protein Niban

0.397

CIART_HUMAN

Circadian-associated transcriptional repressor

0.397

ZN711_HUMAN

Zinc finger protein 711

0.397

IAPP_HUMAN

Islet amyloid polypeptide

0.397

SHSA6_HUMAN

Protein shisa-6

0.397

S22AN_HUMAN

Solute carrier family 22 member 23

0.397

TIFA_HUMAN

TRAF-interacting protein with FHA domain-containing protein A

0.397

FA83C_HUMAN

Protein FAM83C

0.397

LRTM1_HUMAN

Leucine-rich repeat and transmembrane domain-containing protein 1

0.397

RN152_HUMAN

E3 ubiquitin-protein ligase RNF152

0.397

F163A_HUMAN

Protein FAM163A

0.397

SYNCI_HUMAN

Syncoilin

0.397

SMPX_HUMAN

Small muscular protein

0.397

DQA2_HUMAN

HLA class II histocompatibility antigen, DQ alpha 2 chain

0.397

PAR1_HUMAN

Proteinase-activated receptor 1

0.397

CRF_HUMAN

Corticoliberin

0.397

SEM7A_HUMAN

Semaphorin-7A

0.397

ANFC_HUMAN

C-type natriuretic peptide

0.397

LYRIC_HUMAN

Protein LYRIC

0.397

XCR1_HUMAN

Chemokine XC receptor 1

0.397

CART_HUMAN

Cocaine- and amphetamine-regulated transcript protein

0.397

CSH1_HUMAN

Chorionic somatomammotropin hormone 1

0.397

AGR2_HUMAN

Anterior gradient protein 2 homolog

0.397

CNTFR_HUMAN

Ciliary neurotrophic factor receptor subunit alpha

0.397

CK2N2_HUMAN

Calcium/calmodulin-dependent protein kinase II inhibitor 2

0.397

MYCT1_HUMAN

Myc target protein 1

0.397

GPR1_HUMAN

G-protein coupled receptor 1

0.397

CD048_HUMAN

Neuropeptide-like protein C4orf48

0.397

CLUL1_HUMAN

Clusterin-like protein 1

0.397

GPR34_HUMAN

Probable G-protein coupled receptor 34

0.397

UIMC1_HUMAN

BRCA1-A complex subunit RAP80

0.397

ZN653_HUMAN

Zinc finger protein 653

0.397

INSY2_HUMAN

Inhibitory synaptic factor 2A

0.397

ZN652_HUMAN

Zinc finger protein 652

0.397

INHA_HUMAN

Inhibin alpha chain

0.397

GPC5C_HUMAN

G-protein coupled receptor family C group 5 member C

0.397

PIGR_HUMAN

Polymeric immunoglobulin receptor

0.397

GPR18_HUMAN

N-arachidonyl glycine receptor

0.397

VTM2L_HUMAN

V-set and transmembrane domain-containing protein 2-like protein

0.397

LPAR6_HUMAN

Lysophosphatidic acid receptor 6

0.397

CNBP1_HUMAN

Beta-catenin-interacting protein 1

0.397

INAVA_HUMAN

Innate immunity activator protein

0.397

PCD10_HUMAN

Protocadherin-10

0.397

ZBT25_HUMAN

Zinc finger and BTB domain-containing protein 25

0.397

ATOH7_HUMAN

Protein atonal homolog 7

0.397

HEG1_HUMAN

Protein HEG homolog 1

0.397

TM233_HUMAN

Transmembrane protein 233

0.397

ARTN_HUMAN

Artemin

0.397

SOMA_HUMAN

Somatotropin

0.397

ACKR4_HUMAN

Atypical chemokine receptor 4

0.397

TAC2N_HUMAN

Tandem C2 domains nuclear protein

0.397

CSH2_HUMAN

Chorionic somatomammotropin hormone 2

0.397

ZN217_HUMAN

Zinc finger protein 217

0.397

SOM2_HUMAN

Growth hormone variant

0.397

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

TIFA_HUMAN

TRAF-interacting protein with FHA domain-containing protein A

0.329

ACKR4_HUMAN

Atypical chemokine receptor 4

0.345

GPR55_HUMAN

G-protein coupled receptor 55

0.360

GPR20_HUMAN

G-protein coupled receptor 20

0.376

EMB_HUMAN

Embigin

0.397

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 76 organisms (of 929)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy