MITD1_HUMAN 2019

Gene Name MITD1

Description MIT domain-containing protein 1

Length 249

9606

Sequence

>sp|Q8WV92|MITD1_HUMAN MIT domain-containing protein 1
MAKSGLRQDPQSTAAATVLKRAVELDSESRYPQALVCYQEGIDLLLQVLKGTKDNTKRCNLREKISKYMDRAENIKKYLDQEKEDGKYHKQIKIEENATGFSYESLFREYLNETVTEVWIEDPYIRHTHQLYNFLRFCEMLIKRPCKVKTIHLLTSLDEGIEQVQQSRGLQEIEESLRSHGVLLEVQYSSSIHDREIRFNNGWMIKIGRGLDYFKKPQSRFSLGYCDFDLRPCHETTVDIFHKKHTKNI

Domains

Loading...

Help

What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

TM39B_HUMAN

Transmembrane protein 39B

0.396

TTC17_HUMAN

Tetratricopeptide repeat protein 17

0.400

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

WDR37_HUMAN

WD repeat-containing protein 37

0.341

P85A_HUMAN

Phosphatidylinositol 3-kinase regulatory subunit alpha

0.353

RT22_HUMAN

28S ribosomal protein S22, mitochondrial

0.359

BMP4_HUMAN

Bone morphogenetic protein 4

0.359

TM39A_HUMAN

Transmembrane protein 39A

0.360

AFAD_HUMAN

Afadin

0.362

NDUAA_HUMAN

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial

0.362

RGAP1_HUMAN

Rac GTPase-activating protein 1

0.363

HD_HUMAN

Huntingtin

0.363

PDC10_HUMAN

Programmed cell death protein 10

0.364

TM39B_HUMAN

Transmembrane protein 39B

0.366

UNC79_HUMAN

Protein unc-79 homolog

0.367

ERP44_HUMAN

Endoplasmic reticulum resident protein 44

0.369

BMP2_HUMAN

Bone morphogenetic protein 2

0.370

UBR5_HUMAN

E3 ubiquitin-protein ligase UBR5

0.371

RIMB2_HUMAN

RIMS-binding protein 2

0.372

TTC17_HUMAN

Tetratricopeptide repeat protein 17

0.373

RHG17_HUMAN

Rho GTPase-activating protein 17

0.374

PACS1_HUMAN

Phosphofurin acidic cluster sorting protein 1

0.374

PP4P2_HUMAN

Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

0.379

CSKP_HUMAN

Peripheral plasma membrane protein CASK

0.381

MIGA2_HUMAN

Mitoguardin 2

0.382

HINFP_HUMAN

Histone H4 transcription factor

0.382

CACB2_HUMAN

Voltage-dependent L-type calcium channel subunit beta-2

0.382

PICK1_HUMAN

PRKCA-binding protein

0.382

BICD1_HUMAN

Protein bicaudal D homolog 1

0.384

RUND1_HUMAN

RUN domain-containing protein 1

0.384

NDST1_HUMAN

Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1

0.385

ZO1_HUMAN

Tight junction protein ZO-1

0.385

CYLD_HUMAN

Ubiquitin carboxyl-terminal hydrolase CYLD

0.385

HS2ST_HUMAN

Heparan sulfate 2-O-sulfotransferase 1

0.386

ITB1_HUMAN

Integrin beta-1

0.386

CNTP1_HUMAN

Contactin-associated protein 1

0.386

PCX1_HUMAN

Pecanex-like protein 1

0.387

TAOK1_HUMAN

Serine/threonine-protein kinase TAO1

0.387

DAB1_HUMAN

Disabled homolog 1

0.387

ARFP1_HUMAN

Arfaptin-1

0.388

TAOK3_HUMAN

Serine/threonine-protein kinase TAO3

0.388

RSBNL_HUMAN

Round spermatid basic protein 1-like protein

0.388

CBL_HUMAN

E3 ubiquitin-protein ligase CBL

0.388

VRK1_HUMAN

Serine/threonine-protein kinase VRK1

0.388

FERM1_HUMAN

Fermitin family homolog 1

0.389

WLS_HUMAN

Protein wntless homolog

0.389

FERM2_HUMAN

Fermitin family homolog 2

0.389

CACB4_HUMAN

Voltage-dependent L-type calcium channel subunit beta-4

0.389

MAPK2_HUMAN

MAP kinase-activated protein kinase 2

0.389

KPBB_HUMAN

Phosphorylase b kinase regulatory subunit beta

0.389

TRIO_HUMAN

Triple functional domain protein

0.389

BICD2_HUMAN

Protein bicaudal D homolog 2

0.389

NDST2_HUMAN

Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2

0.390

STON1_HUMAN

Stonin-1

0.390

GIT2_HUMAN

ARF GTPase-activating protein GIT2

0.390

E41L5_HUMAN

Band 4.1-like protein 5

0.391

CPEB1_HUMAN

Cytoplasmic polyadenylation element-binding protein 1

0.391

ZO2_HUMAN

Tight junction protein ZO-2

0.391

SNRK_HUMAN

SNF-related serine/threonine-protein kinase

0.392

SPE39_HUMAN

Spermatogenesis-defective protein 39 homolog

0.393

OPA1_HUMAN

Dynamin-like 120 kDa protein, mitochondrial

0.393

YAF2_HUMAN

YY1-associated factor 2

0.393

AT1B1_HUMAN

Sodium/potassium-transporting ATPase subunit beta-1

0.394

AT1B4_HUMAN

Protein ATP1B4

0.394

ANKL2_HUMAN

Ankyrin repeat and LEM domain-containing protein 2

0.394

SNX6_HUMAN

Sorting nexin-6

0.395

ILF2_HUMAN

Interleukin enhancer-binding factor 2

0.395

JIP4_HUMAN

C-Jun-amino-terminal kinase-interacting protein 4

0.395

MAPK3_HUMAN

MAP kinase-activated protein kinase 3

0.395

NUMB_HUMAN

Protein numb homolog

0.395

C43BP_HUMAN

Collagen type IV alpha-3-binding protein

0.395

TEF_HUMAN

Thyrotroph embryonic factor

0.395

TSN5_HUMAN

Tetraspanin-5

0.395

HTF4_HUMAN

Transcription factor 12

0.395

ANLN_HUMAN

Anillin

0.395

ECSIT_HUMAN

Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

0.395

SSRG_HUMAN

Translocon-associated protein subunit gamma

0.396

FA8A1_HUMAN

Protein FAM8A1

0.396

SO4A1_HUMAN

Solute carrier organic anion transporter family member 4A1

0.396

IP3KB_HUMAN

Inositol-trisphosphate 3-kinase B

0.397

SMCE1_HUMAN

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

0.398

MPDZ_HUMAN

Multiple PDZ domain protein

0.398

RM40_HUMAN

39S ribosomal protein L40, mitochondrial

0.398

PACN1_HUMAN

Protein kinase C and casein kinase substrate in neurons protein 1

0.399

OFUT1_HUMAN

GDP-fucose protein O-fucosyltransferase 1

0.400

PAR6B_HUMAN

Partitioning defective 6 homolog beta

0.400

TM38A_HUMAN

Trimeric intracellular cation channel type A

0.400

TNIK_HUMAN

TRAF2 and NCK-interacting protein kinase

0.400

SNX27_HUMAN

Sorting nexin-27

0.400

APBA2_HUMAN

Amyloid-beta A4 precursor protein-binding family A member 2

0.400

MTA1_HUMAN

Metastasis-associated protein MTA1

0.400

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 47 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy