MBOA7_HUMAN 2019

Gene Name MBOA7

Description Lysophospholipid acyltransferase 7

Length 472

9606

Sequence

>sp|Q96N66|MBOA7_HUMAN Lysophospholipid acyltransferase 7
MSPEEWTYLVVLLISIPIGFLFKKAGPGLKRWGAAAVGLGLTLFTCGPHTLHSLVTILGTWALIQAQPCSCHALALAWTFSYLLFFRALSLLGLPTPTPFTNAVQLLLTLKLVSLASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFRMRFYVAWIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTDFCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLTIPLCLAAEGRLESALRGRLSPGGQKAWDWVHWFLKMRAYDYMCMGFVLLSLADTLRYWASIYFCIHFLALAALGLGLALGGGSPSRRKAASQPTSLAPEKLREE

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

No protein with similar profile across the domains were found

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

PP4P1_HUMAN

Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

0.335

AT1B2_HUMAN

Sodium/potassium-transporting ATPase subunit beta-2

0.350

TSN17_HUMAN

Tetraspanin-17

0.356

GLCE_HUMAN

D-glucuronyl C5-epimerase

0.357

ELF4_HUMAN

ETS-related transcription factor Elf-4

0.361

IP3KC_HUMAN

Inositol-trisphosphate 3-kinase C

0.367

DVL2_HUMAN

Segment polarity protein dishevelled homolog DVL-2

0.367

ILF2_HUMAN

Interleukin enhancer-binding factor 2

0.370

BMP4_HUMAN

Bone morphogenetic protein 4

0.370

NUMB_HUMAN

Protein numb homolog

0.370

ECSIT_HUMAN

Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

0.370

CNTP1_HUMAN

Contactin-associated protein 1

0.372

RGAP1_HUMAN

Rac GTPase-activating protein 1

0.373

TRIO_HUMAN

Triple functional domain protein

0.375

P85A_HUMAN

Phosphatidylinositol 3-kinase regulatory subunit alpha

0.375

PHKG2_HUMAN

Phosphorylase b kinase gamma catalytic chain, liver/testis isoform

0.376

BMP2_HUMAN

Bone morphogenetic protein 2

0.380

PLXA3_HUMAN

Plexin-A3

0.380

AT1B1_HUMAN

Sodium/potassium-transporting ATPase subunit beta-1

0.381

AT1B4_HUMAN

Protein ATP1B4

0.381

HINFP_HUMAN

Histone H4 transcription factor

0.381

SC5A8_HUMAN

Sodium-coupled monocarboxylate transporter 1

0.381

TMOD4_HUMAN

Tropomodulin-4

0.382

RUND1_HUMAN

RUN domain-containing protein 1

0.383

TSN5_HUMAN

Tetraspanin-5

0.383

RIMS2_HUMAN

Regulating synaptic membrane exocytosis protein 2

0.383

RUNX2_HUMAN

Runt-related transcription factor 2

0.383

RB6I2_HUMAN

ELKS/Rab6-interacting/CAST family member 1

0.383

ITB1_HUMAN

Integrin beta-1

0.384

PAR6A_HUMAN

Partitioning defective 6 homolog alpha

0.384

RIMS1_HUMAN

Regulating synaptic membrane exocytosis protein 1

0.385

CACB1_HUMAN

Voltage-dependent L-type calcium channel subunit beta-1

0.385

FBX25_HUMAN

F-box only protein 25

0.385

DVL3_HUMAN

Segment polarity protein dishevelled homolog DVL-3

0.386

SPRY7_HUMAN

SPRY domain-containing protein 7

0.386

MINK1_HUMAN

Misshapen-like kinase 1

0.386

APBA2_HUMAN

Amyloid-beta A4 precursor protein-binding family A member 2

0.387

FERM2_HUMAN

Fermitin family homolog 2

0.387

TM38A_HUMAN

Trimeric intracellular cation channel type A

0.387

SMAD1_HUMAN

Mothers against decapentaplegic homolog 1

0.388

SSRD_HUMAN

Translocon-associated protein subunit delta

0.388

BEST2_HUMAN

Bestrophin-2

0.388

RIPL1_HUMAN

RILP-like protein 1

0.389

FLI1_HUMAN

Friend leukemia integration 1 transcription factor

0.389

ROBO2_HUMAN

Roundabout homolog 2

0.389

LIPA3_HUMAN

Liprin-alpha-3

0.389

UNC5D_HUMAN

Netrin receptor UNC5D

0.390

3BP5L_HUMAN

SH3 domain-binding protein 5-like

0.391

RIMS4_HUMAN

Regulating synaptic membrane exocytosis protein 4

0.391

TM38B_HUMAN

Trimeric intracellular cation channel type B

0.391

OPA1_HUMAN

Dynamin-like 120 kDa protein, mitochondrial

0.391

ACADV_HUMAN

Very long-chain specific acyl-CoA dehydrogenase, mitochondrial

0.391

PCX3_HUMAN

Pecanex-like protein 3

0.392

SLIT1_HUMAN

Slit homolog 1 protein

0.392

BAP18_HUMAN

Chromatin complexes subunit BAP18

0.392

PLXA2_HUMAN

Plexin-A2

0.392

VAV2_HUMAN

Guanine nucleotide exchange factor VAV2

0.393

RT25_HUMAN

28S ribosomal protein S25, mitochondrial

0.393

RSBN1_HUMAN

Lysine-specific demethylase 9

0.393

MAPK3_HUMAN

MAP kinase-activated protein kinase 3

0.393

ARFP2_HUMAN

Arfaptin-2

0.393

MED19_HUMAN

Mediator of RNA polymerase II transcription subunit 19

0.393

APBA1_HUMAN

Amyloid-beta A4 precursor protein-binding family A member 1

0.393

AT1B3_HUMAN

Sodium/potassium-transporting ATPase subunit beta-3

0.394

CSRN2_HUMAN

Cysteine/serine-rich nuclear protein 2

0.395

FA8A1_HUMAN

Protein FAM8A1

0.395

BAF_HUMAN

Barrier-to-autointegration factor

0.395

PACS1_HUMAN

Phosphofurin acidic cluster sorting protein 1

0.395

PO4F3_HUMAN

POU domain, class 4, transcription factor 3

0.396

ELF2_HUMAN

ETS-related transcription factor Elf-2

0.396

CREL2_HUMAN

Cysteine-rich with EGF-like domain protein 2

0.396

SMCE1_HUMAN

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

0.396

MED11_HUMAN

Mediator of RNA polymerase II transcription subunit 11

0.397

URP2_HUMAN

Fermitin family homolog 3

0.397

CSTN3_HUMAN

Calsyntenin-3

0.397

RIMS3_HUMAN

Regulating synaptic membrane exocytosis protein 3

0.397

FLOWR_HUMAN

Calcium channel flower homolog

0.398

JIP1_HUMAN

C-Jun-amino-terminal kinase-interacting protein 1

0.398

FERM1_HUMAN

Fermitin family homolog 1

0.398

WLS_HUMAN

Protein wntless homolog

0.398

PAR6B_HUMAN

Partitioning defective 6 homolog beta

0.398

MAPK2_HUMAN

MAP kinase-activated protein kinase 2

0.398

MIGA1_HUMAN

Mitoguardin 1

0.399

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 45 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy