F118B_HUMAN 2019

Gene Name F118B

Description Protein FAM118B

Length 351

9606

Sequence

>sp|Q9BPY3|F118B_HUMAN Protein FAM118B
MASTGSQASDIDEIFGFFNDGEPPTKKPRKLLPSLKTKKPRELVLVIGTGISAAVAPQVPALKSWKGLIQALLDAAIDFDLLEDEESKKFQKCLHEDKNLVHVAHDLIQKLSPRTSNVRSTFFKDCLYEVFDDLESKMEDSGKQLLQSVLHLMENGALVLTTNFDNLLELYAADQGKQLESLDLTDEKKVLEWAQEKRKLSVLHIHGVYTNPSGIVLHPAGYQNVLRNTEVMREIQKLYENKSFLFLGCGWTVDDTTFQALFLEAVKHKSDLEHFMLVRRGDVDEFKKLRENMLDKGIKVISYGDDYADLPEYFKRLTCEISTRGTSAGMVREGQLNGSSAAHSEIRGCST

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

No protein with similar profile across the domains were found

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

ZN644_HUMAN

Zinc finger protein 644

0.383

P33MX_HUMAN

Putative monooxygenase p33MONOX

0.383

ZN131_HUMAN

Zinc finger protein 131

0.383

PDGFC_HUMAN

Platelet-derived growth factor C

0.383

OCLN_HUMAN

Occludin

0.383

MERB1_HUMAN

bMERB domain-containing protein 1

0.383

MFA3L_HUMAN

Microfibrillar-associated protein 3-like

0.383

NEXMI_HUMAN

Neurite extension and migration factor

0.383

MYZAP_HUMAN

Myocardial zonula adherens protein

0.383

ADNP_HUMAN

Activity-dependent neuroprotector homeobox protein

0.383

GHR_HUMAN

Growth hormone receptor

0.383

LEG1_HUMAN

Galectin-1

0.383

VSTM4_HUMAN

V-set and transmembrane domain-containing protein 4

0.383

SYBU_HUMAN

Syntabulin

0.383

PENK_HUMAN

Proenkephalin-A

0.383

PRL_HUMAN

Prolactin

0.383

NPY_HUMAN

Pro-neuropeptide Y

0.383

ZPLD1_HUMAN

Zona pellucida-like domain-containing protein 1

0.383

PGFRL_HUMAN

Platelet-derived growth factor receptor-like protein

0.385

REST_HUMAN

RE1-silencing transcription factor

0.385

HBEGF_HUMAN

Proheparin-binding EGF-like growth factor

0.385

FNDC7_HUMAN

Fibronectin type III domain-containing protein 7

0.385

CC126_HUMAN

Coiled-coil domain-containing protein 126

0.385

R7BP_HUMAN

Regulator of G-protein signaling 7-binding protein

0.385

CFAI_HUMAN

Complement factor I

0.385

ZN652_HUMAN

Zinc finger protein 652

0.385

AL5AP_HUMAN

Arachidonate 5-lipoxygenase-activating protein

0.387

CEP55_HUMAN

Centrosomal protein of 55 kDa

0.394

ZN142_HUMAN

Zinc finger protein 142

0.394

CCD80_HUMAN

Coiled-coil domain-containing protein 80

0.394

CD166_HUMAN

CD166 antigen

0.394

GCR_HUMAN

Glucocorticoid receptor

0.394

LUR1L_HUMAN

Leucine rich adaptor protein 1-like

0.396

CCR7_HUMAN

C-C chemokine receptor type 7

0.396

CXCR4_HUMAN

C-X-C chemokine receptor type 4

0.396

SKA3_HUMAN

Spindle and kinetochore-associated protein 3

0.396

CDCP1_HUMAN

CUB domain-containing protein 1

0.396

CKLF3_HUMAN

CKLF-like MARVEL transmembrane domain-containing protein 3

0.396

ZN335_HUMAN

Zinc finger protein 335

0.396

EDAR_HUMAN

Tumor necrosis factor receptor superfamily member EDAR

0.396

F131B_HUMAN

Protein FAM131B

0.396

ZP3_HUMAN

Zona pellucida sperm-binding protein 3

0.396

GDNF_HUMAN

Glial cell line-derived neurotrophic factor

0.396

TANK_HUMAN

TRAF family member-associated NF-kappa-B activator

0.396

CLD11_HUMAN

Claudin-11

0.396

LEPR_HUMAN

Leptin receptor

0.396

AKA11_HUMAN

A-kinase anchor protein 11

0.396

GPNMB_HUMAN

Transmembrane glycoprotein NMB

0.396

FMOD_HUMAN

Fibromodulin

0.396

CAD17_HUMAN

Cadherin-17

0.396

FPRP_HUMAN

Prostaglandin F2 receptor negative regulator

0.396

ZBT18_HUMAN

Zinc finger and BTB domain-containing protein 18

0.396

LRC52_HUMAN

Leucine-rich repeat-containing protein 52

0.396

CO8B_HUMAN

Complement component C8 beta chain

0.396

PALMD_HUMAN

Palmdelphin

0.396

AZI2_HUMAN

5-azacytidine-induced protein 2

0.396

MNAR1_HUMAN

Major intrinsically disordered Notch2-binding receptor 1

0.396

SPIN1_HUMAN

Spindlin-1

0.396

TF_HUMAN

Tissue factor

0.396

CXD2_HUMAN

Gap junction delta-2 protein

0.396

TEFF1_HUMAN

Tomoregulin-1

0.396

F1711_HUMAN

Protein FAM171A1

0.396

ZBTB2_HUMAN

Zinc finger and BTB domain-containing protein 2

0.396

ANGT_HUMAN

Angiotensinogen

0.396

PHAG1_HUMAN

Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

0.396

ITGBL_HUMAN

Integrin beta-like protein 1

0.396

M3K8_HUMAN

Mitogen-activated protein kinase kinase kinase 8

0.396

ZBT16_HUMAN

Zinc finger and BTB domain-containing protein 16

0.396

ZBTB1_HUMAN

Zinc finger and BTB domain-containing protein 1

0.396

RAG2_HUMAN

V(D)J recombination-activating protein 2

0.396

TMM51_HUMAN

Transmembrane protein 51

0.396

ABEC2_HUMAN

C->U-editing enzyme APOBEC-2

0.396

NLRX1_HUMAN

NLR family member X1

0.396

VCAM1_HUMAN

Vascular cell adhesion protein 1

0.396

LUZP1_HUMAN

Leucine zipper protein 1

0.396

BFSP1_HUMAN

Filensin

0.396

SMS_HUMAN

Somatostatin

0.396

PTHR_HUMAN

Parathyroid hormone-related protein

0.396

PRDM5_HUMAN

PR domain zinc finger protein 5

0.396

LYRIC_HUMAN

Protein LYRIC

0.396

MBP_HUMAN

Myelin basic protein

0.396

NYAP2_HUMAN

Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2

0.396

CCSE2_HUMAN

Serine-rich coiled-coil domain-containing protein 2

0.396

ZN711_HUMAN

Zinc finger protein 711

0.398

TECTB_HUMAN

Beta-tectorin

0.398

XK_HUMAN

Membrane transport protein XK

0.398

F163A_HUMAN

Protein FAM163A

0.398

OGR1_HUMAN

Ovarian cancer G-protein coupled receptor 1

0.398

EMB_HUMAN

Embigin

0.398

IL12B_HUMAN

Interleukin-12 subunit beta

0.398

PCD10_HUMAN

Protocadherin-10

0.398

PD1L1_HUMAN

Programmed cell death 1 ligand 1

0.398

CLCF1_HUMAN

Cardiotrophin-like cytokine factor 1

0.398

TNR25_HUMAN

Tumor necrosis factor receptor superfamily member 25

0.400

CNTFR_HUMAN

Ciliary neurotrophic factor receptor subunit alpha

0.400

LYVE1_HUMAN

Lymphatic vessel endothelial hyaluronic acid receptor 1

0.400

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 19 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy