FAP24_HUMAN 2019

Gene Name FAP24

Description Fanconi anemia core complex-associated protein 24

Length 215

9606

Sequence

>sp|Q9BTP7|FAP24_HUMAN Fanconi anemia core complex-associated protein 24
MEKNPPDDTGPVHVPLGHIVANEKWRGSQLAQEMQGKIKLIFEDGLTPDFYLSNRCCILYVTEADLVAGNGYRKRLVRVRNSNNLKGIVVVEKTRMSEQYFPALQKFTVLDLGMVLLPVASQMEASCLVIQLVQEQTKEPSKNPLLGKKRALLLSEPSLLRTVQQIPGVGKVKAPLLLQKFPSIQQLSNASIGELEQVVGQAVAQQIHAFFTQPR

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

RD3_HUMAN

Protein RD3

0.371

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

IRF1_HUMAN

Interferon regulatory factor 1

0.327

SPICE_HUMAN

Spindle and centriole-associated protein 1

0.342

SNP47_HUMAN

Synaptosomal-associated protein 47

0.344

CCD18_HUMAN

Coiled-coil domain-containing protein 18

0.345

RN219_HUMAN

RING finger protein 219

0.352

IRF2_HUMAN

Interferon regulatory factor 2

0.352

CEP85_HUMAN

Centrosomal protein of 85 kDa

0.354

KNDC1_HUMAN

Kinase non-catalytic C-lobe domain-containing protein 1

0.355

NKAP1_HUMAN

Uncharacterized protein NKAPD1

0.355

RD3_HUMAN

Protein RD3

0.355

CNST_HUMAN

Consortin

0.360

SLF2_HUMAN

SMC5-SMC6 complex localization factor protein 2

0.360

PHF24_HUMAN

PHD finger protein 24

0.360

PJVK_HUMAN

Pejvakin

0.362

HAUS8_HUMAN

HAUS augmin-like complex subunit 8

0.362

CCNF_HUMAN

Cyclin-F

0.364

TICRR_HUMAN

Treslin

0.366

LRC42_HUMAN

Leucine-rich repeat-containing protein 42

0.366

FBXW2_HUMAN

F-box/WD repeat-containing protein 2

0.366

TAF1A_HUMAN

TATA box-binding protein-associated factor RNA polymerase I subunit A

0.366

F167A_HUMAN

Protein FAM167A

0.366

ZFY27_HUMAN

Protrudin

0.368

WDCP_HUMAN

WD repeat and coiled-coil-containing protein

0.368

MOONR_HUMAN

Protein moonraker

0.369

SFRP3_HUMAN

Secreted frizzled-related protein 3

0.371

DERM_HUMAN

Dermatopontin

0.373

CC157_HUMAN

Coiled-coil domain-containing protein 157

0.375

FBXL5_HUMAN

F-box/LRR-repeat protein 5

0.375

IKBP1_HUMAN

Interleukin-1 receptor-associated kinase 1-binding protein 1

0.375

TSN3_HUMAN

Tetraspanin-3

0.376

OIT3_HUMAN

Oncoprotein-induced transcript 3 protein

0.376

HUNK_HUMAN

Hormonally up-regulated neu tumor-associated kinase

0.376

USPL1_HUMAN

SUMO-specific isopeptidase USPL1

0.378

AMPO_HUMAN

Aminopeptidase O

0.380

NSMF_HUMAN

NMDA receptor synaptonuclear signaling and neuronal migration factor

0.381

AP1AR_HUMAN

AP-1 complex-associated regulatory protein

0.381

MID51_HUMAN

Mitochondrial dynamics protein MID51

0.381

PRD12_HUMAN

PR domain zinc finger protein 12

0.381

GSDME_HUMAN

Gasdermin-E

0.383

F124B_HUMAN

Protein FAM124B

0.383

CASC4_HUMAN

Protein CASC4

0.385

STXB4_HUMAN

Syntaxin-binding protein 4

0.386

TXD16_HUMAN

Thioredoxin domain-containing protein 16

0.388

PARI_HUMAN

PCNA-interacting partner

0.388

SHOT1_HUMAN

Shootin-1

0.388

MTBP_HUMAN

Mdm2-binding protein

0.388

3BP2_HUMAN

SH3 domain-binding protein 2

0.390

NCOA4_HUMAN

Nuclear receptor coactivator 4

0.390

MIPO1_HUMAN

Mirror-image polydactyly gene 1 protein

0.391

PCD20_HUMAN

Protocadherin-20

0.391

CC171_HUMAN

Coiled-coil domain-containing protein 171

0.391

CF062_HUMAN

Uncharacterized protein C6orf62

0.391

SPIDR_HUMAN

DNA repair-scaffolding protein

0.391

F124A_HUMAN

Protein FAM124A

0.391

CTHR1_HUMAN

Collagen triple helix repeat-containing protein 1

0.393

PRDM4_HUMAN

PR domain zinc finger protein 4

0.393

STRA6_HUMAN

Receptor for retinol uptake STRA6

0.394

IQCB1_HUMAN

IQ calmodulin-binding motif-containing protein 1

0.394

ZN451_HUMAN

E3 SUMO-protein ligase ZNF451

0.395

PEAK1_HUMAN

Inactive tyrosine-protein kinase PEAK1

0.395

TNF10_HUMAN

Tumor necrosis factor ligand superfamily member 10

0.395

GEMI4_HUMAN

Gem-associated protein 4

0.395

GP173_HUMAN

Probable G-protein coupled receptor 173

0.395

MIEAP_HUMAN

Mitochondria-eating protein

0.396

ENO4_HUMAN

Enolase 4

0.396

B2L13_HUMAN

Bcl-2-like protein 13

0.397

GP161_HUMAN

G-protein coupled receptor 161

0.397

CEP63_HUMAN

Centrosomal protein of 63 kDa

0.399

BST1_HUMAN

ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2

0.399

VCIP1_HUMAN

Deubiquitinating protein VCIP135

0.400

DCA17_HUMAN

DDB1- and CUL4-associated factor 17

0.400

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 26 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy