RAB20_HUMAN 2019

Gene Name RAB20

Description Ras-related protein Rab-20

Length 234

9606

Sequence

>sp|Q9NX57|RAB20_HUMAN Ras-related protein Rab-20
MRKPDSKIVLLGDMNVGKTSLLQRYMERRFPDTVSTVGGAFYLKQWRSYNISIWDTAGREQFHGLGSMYCRGAAAIILTYDVNHRQSLVELEDRFLGLTDTASKDCLFAIVGNKVDLTEEGALAGQEKEECSPNMDAGDRVSPRAPKQVQLEDAVALYKKILKYKMLDEQDVPAAEQMCFETSAKTGYNVDLLFETLFDLVVPMILQQRAERPSHTVDISSHKPPKRTRSGCCA

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

SPICE_HUMAN

Spindle and centriole-associated protein 1

0.378

GPR45_HUMAN

Probable G-protein coupled receptor 45

0.392

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

SPICE_HUMAN

Spindle and centriole-associated protein 1

0.289

IRF1_HUMAN

Interferon regulatory factor 1

0.302

CEP85_HUMAN

Centrosomal protein of 85 kDa

0.303

CCNF_HUMAN

Cyclin-F

0.316

TICRR_HUMAN

Treslin

0.318

LRC42_HUMAN

Leucine-rich repeat-containing protein 42

0.318

SNP47_HUMAN

Synaptosomal-associated protein 47

0.319

IRF2_HUMAN

Interferon regulatory factor 2

0.329

KNDC1_HUMAN

Kinase non-catalytic C-lobe domain-containing protein 1

0.332

RD3_HUMAN

Protein RD3

0.332

AMPO_HUMAN

Aminopeptidase O

0.333

PRD12_HUMAN

PR domain zinc finger protein 12

0.335

DIXC1_HUMAN

Dixin

0.336

STXB4_HUMAN

Syntaxin-binding protein 4

0.342

FBXW8_HUMAN

F-box/WD repeat-containing protein 8

0.342

MTBP_HUMAN

Mdm2-binding protein

0.344

TXD16_HUMAN

Thioredoxin domain-containing protein 16

0.344

F167A_HUMAN

Protein FAM167A

0.344

WDCP_HUMAN

WD repeat and coiled-coil-containing protein

0.345

MOONR_HUMAN

Protein moonraker

0.347

STRA6_HUMAN

Receptor for retinol uptake STRA6

0.352

CP20A_HUMAN

Cytochrome P450 20A1

0.352

FBXL5_HUMAN

F-box/LRR-repeat protein 5

0.354

IKBP1_HUMAN

Interleukin-1 receptor-associated kinase 1-binding protein 1

0.354

HUNK_HUMAN

Hormonally up-regulated neu tumor-associated kinase

0.355

GP161_HUMAN

G-protein coupled receptor 161

0.355

NKAP1_HUMAN

Uncharacterized protein NKAPD1

0.357

USPL1_HUMAN

SUMO-specific isopeptidase USPL1

0.357

DCA17_HUMAN

DDB1- and CUL4-associated factor 17

0.360

VCIP1_HUMAN

Deubiquitinating protein VCIP135

0.360

NSMF_HUMAN

NMDA receptor synaptonuclear signaling and neuronal migration factor

0.360

MID51_HUMAN

Mitochondrial dynamics protein MID51

0.360

ZFAT_HUMAN

Zinc finger protein ZFAT

0.360

DBLOH_HUMAN

Diablo homolog, mitochondrial

0.360

BOREA_HUMAN

Borealin

0.368

RGS22_HUMAN

Regulator of G-protein signaling 22

0.368

GSE1_HUMAN

Genetic suppressor element 1

0.368

FBXW2_HUMAN

F-box/WD repeat-containing protein 2

0.368

NPAT_HUMAN

Protein NPAT

0.369

SOSD1_HUMAN

Sclerostin domain-containing protein 1

0.371

MIPO1_HUMAN

Mirror-image polydactyly gene 1 protein

0.371

PRDM4_HUMAN

PR domain zinc finger protein 4

0.373

FANCB_HUMAN

Fanconi anemia group B protein

0.373

SFRP3_HUMAN

Secreted frizzled-related protein 3

0.373

SLAI2_HUMAN

SLAIN motif-containing protein 2

0.374

GPR63_HUMAN

Probable G-protein coupled receptor 63

0.374

PEAK1_HUMAN

Inactive tyrosine-protein kinase PEAK1

0.374

IQCB1_HUMAN

IQ calmodulin-binding motif-containing protein 1

0.375

ENO4_HUMAN

Enolase 4

0.376

HECD4_HUMAN

Probable E3 ubiquitin-protein ligase HECTD4

0.376

RADIL_HUMAN

Ras-associating and dilute domain-containing protein

0.378

DEND3_HUMAN

DENN domain-containing protein 3

0.378

OIT3_HUMAN

Oncoprotein-induced transcript 3 protein

0.378

F219A_HUMAN

Protein FAM219A

0.381

NUSAP_HUMAN

Nucleolar and spindle-associated protein 1

0.381

AP1AR_HUMAN

AP-1 complex-associated regulatory protein

0.383

LBN_HUMAN

Limbin

0.383

F199X_HUMAN

Protein FAM199X

0.383

PHF24_HUMAN

PHD finger protein 24

0.385

CNST_HUMAN

Consortin

0.385

SLF2_HUMAN

SMC5-SMC6 complex localization factor protein 2

0.385

GSDME_HUMAN

Gasdermin-E

0.385

BCL10_HUMAN

B-cell lymphoma/leukemia 10

0.385

FBX4_HUMAN

F-box only protein 4

0.386

SELN_HUMAN

Selenoprotein N

0.388

TM168_HUMAN

Transmembrane protein 168

0.390

TAF1A_HUMAN

TATA box-binding protein-associated factor RNA polymerase I subunit A

0.390

PARI_HUMAN

PCNA-interacting partner

0.390

ZFY27_HUMAN

Protrudin

0.391

TGBR3_HUMAN

Transforming growth factor beta receptor type 3

0.391

FBX41_HUMAN

F-box only protein 41

0.391

NCOA4_HUMAN

Nuclear receptor coactivator 4

0.391

TAXB1_HUMAN

Tax1-binding protein 1

0.392

ZN366_HUMAN

Zinc finger protein 366

0.393

TM101_HUMAN

Transmembrane protein 101

0.393

JMY_HUMAN

Junction-mediating and -regulatory protein

0.393

F124A_HUMAN

Protein FAM124A

0.393

CPLN1_HUMAN

Ciliogenesis and planar polarity effector 1

0.393

ESR2_HUMAN

Estrogen receptor beta

0.393

CCD18_HUMAN

Coiled-coil domain-containing protein 18

0.393

SPIDR_HUMAN

DNA repair-scaffolding protein

0.393

CC181_HUMAN

Coiled-coil domain-containing protein 181

0.395

CE051_HUMAN

UPF0600 protein C5orf51

0.395

HRH2_HUMAN

Histamine H2 receptor

0.395

ZN451_HUMAN

E3 SUMO-protein ligase ZNF451

0.397

GEMI4_HUMAN

Gem-associated protein 4

0.397

TNF10_HUMAN

Tumor necrosis factor ligand superfamily member 10

0.397

ICE1_HUMAN

Little elongation complex subunit 1

0.397

GP173_HUMAN

Probable G-protein coupled receptor 173

0.397

MTFR1_HUMAN

Mitochondrial fission regulator 1

0.397

DERM_HUMAN

Dermatopontin

0.397

RN219_HUMAN

RING finger protein 219

0.397

MIEAP_HUMAN

Mitochondria-eating protein

0.397

GARE1_HUMAN

GRB2-associated and regulator of MAPK protein 1

0.397

CC157_HUMAN

Coiled-coil domain-containing protein 157

0.397

DZAN1_HUMAN

Double zinc ribbon and ankyrin repeat-containing protein 1

0.398

CE034_HUMAN

Uncharacterized protein C5orf34

0.399

LRC73_HUMAN

Leucine-rich repeat-containing protein 73

0.399

DEPD7_HUMAN

DEP domain-containing protein 7

0.399

TSN3_HUMAN

Tetraspanin-3

0.399

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 102 organisms (of 929)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy