ARL15_HUMAN 2019

Gene Name ARL15

Description ADP-ribosylation factor-like protein 15

Length 204

9606

Sequence

>sp|Q9NXU5|ARL15_HUMAN ADP-ribosylation factor-like protein 15
MSDLRITEAFLYMDYLCFRALCCKGPPPARPEYDLVCIGLTGSGKTSLLSKLCSESPDNVVSTTGFSIKAVPFQNAILNVKELGGADNIRKYWSRYYQGSQGVIFVLDSASSEDDLEAARNELHSALQHPQLCTLPFLILANHQDKPAARSVQEIKKYFELEPLARGKRWILQPCSLDDMDALKDSFSQLINLLEEKDHEAVRM

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

No protein with similar profile across the domains were found

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

SG196_HUMAN

Protein O-mannose kinase

0.326

FBXW8_HUMAN

F-box/WD repeat-containing protein 8

0.329

SNP47_HUMAN

Synaptosomal-associated protein 47

0.332

IKBP1_HUMAN

Interleukin-1 receptor-associated kinase 1-binding protein 1

0.341

CEP85_HUMAN

Centrosomal protein of 85 kDa

0.342

KNDC1_HUMAN

Kinase non-catalytic C-lobe domain-containing protein 1

0.344

F199X_HUMAN

Protein FAM199X

0.347

SPICE_HUMAN

Spindle and centriole-associated protein 1

0.355

TICRR_HUMAN

Treslin

0.355

RGS22_HUMAN

Regulator of G-protein signaling 22

0.355

F167A_HUMAN

Protein FAM167A

0.355

JMY_HUMAN

Junction-mediating and -regulatory protein

0.358

CF062_HUMAN

Uncharacterized protein C6orf62

0.358

DERM_HUMAN

Dermatopontin

0.362

CP20A_HUMAN

Cytochrome P450 20A1

0.363

CC157_HUMAN

Coiled-coil domain-containing protein 157

0.364

RN219_HUMAN

RING finger protein 219

0.364

LRC73_HUMAN

Leucine-rich repeat-containing protein 73

0.366

TSN3_HUMAN

Tetraspanin-3

0.366

CH034_HUMAN

Uncharacterized protein C8orf34

0.369

F219A_HUMAN

Protein FAM219A

0.369

DCA17_HUMAN

DDB1- and CUL4-associated factor 17

0.370

DIXC1_HUMAN

Dixin

0.370

GNPTG_HUMAN

N-acetylglucosamine-1-phosphotransferase subunit gamma

0.370

THRB_HUMAN

Prothrombin

0.371

MID51_HUMAN

Mitochondrial dynamics protein MID51

0.371

LBN_HUMAN

Limbin

0.371

AP1AR_HUMAN

AP-1 complex-associated regulatory protein

0.371

AF1L1_HUMAN

Actin filament-associated protein 1-like 1

0.373

PHF24_HUMAN

PHD finger protein 24

0.373

AF1L2_HUMAN

Actin filament-associated protein 1-like 2

0.373

BCL10_HUMAN

B-cell lymphoma/leukemia 10

0.373

F124B_HUMAN

Protein FAM124B

0.373

CNST_HUMAN

Consortin

0.373

RFTN1_HUMAN

Raftlin

0.376

CCNF_HUMAN

Cyclin-F

0.376

STXB4_HUMAN

Syntaxin-binding protein 4

0.376

CRDL2_HUMAN

Chordin-like protein 2

0.378

MTBP_HUMAN

Mdm2-binding protein

0.378

LRC42_HUMAN

Leucine-rich repeat-containing protein 42

0.378

TXD16_HUMAN

Thioredoxin domain-containing protein 16

0.378

FBXW2_HUMAN

F-box/WD repeat-containing protein 2

0.378

PAWR_HUMAN

PRKC apoptosis WT1 regulator protein

0.380

NCOA4_HUMAN

Nuclear receptor coactivator 4

0.380

WDCP_HUMAN

WD repeat and coiled-coil-containing protein

0.380

F124A_HUMAN

Protein FAM124A

0.381

MOONR_HUMAN

Protein moonraker

0.381

CCD18_HUMAN

Coiled-coil domain-containing protein 18

0.381

CPLN1_HUMAN

Ciliogenesis and planar polarity effector 1

0.381

TM196_HUMAN

Transmembrane protein 196

0.383

MYRIP_HUMAN

Rab effector MyRIP

0.383

MK06_HUMAN

Mitogen-activated protein kinase 6

0.383

IQCB1_HUMAN

IQ calmodulin-binding motif-containing protein 1

0.384

ZN451_HUMAN

E3 SUMO-protein ligase ZNF451

0.385

TNF10_HUMAN

Tumor necrosis factor ligand superfamily member 10

0.385

IRF2_HUMAN

Interferon regulatory factor 2

0.386

IRF1_HUMAN

Interferon regulatory factor 1

0.386

ENO4_HUMAN

Enolase 4

0.386

MIEAP_HUMAN

Mitochondria-eating protein

0.386

FBXL5_HUMAN

F-box/LRR-repeat protein 5

0.386

CE034_HUMAN

Uncharacterized protein C5orf34

0.388

HUNK_HUMAN

Hormonally up-regulated neu tumor-associated kinase

0.388

OIT3_HUMAN

Oncoprotein-induced transcript 3 protein

0.388

KNOP1_HUMAN

Lysine-rich nucleolar protein 1

0.389

RD3_HUMAN

Protein RD3

0.390

USPL1_HUMAN

SUMO-specific isopeptidase USPL1

0.390

NKAP1_HUMAN

Uncharacterized protein NKAPD1

0.390

BST1_HUMAN

ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2

0.390

ZF64B_HUMAN

Zinc finger protein 64

0.391

CS044_HUMAN

Uncharacterized protein C19orf44

0.391

CNTLN_HUMAN

Centlein

0.391

AMPO_HUMAN

Aminopeptidase O

0.391

PTTG_HUMAN

Pituitary tumor-transforming gene 1 protein-interacting protein

0.392

ZFAT_HUMAN

Zinc finger protein ZFAT

0.393

PRD12_HUMAN

PR domain zinc finger protein 12

0.393

CSPG2_HUMAN

Versican core protein

0.393

FSIP1_HUMAN

Fibrous sheath-interacting protein 1

0.393

AFAP1_HUMAN

Actin filament-associated protein 1

0.393

GSDME_HUMAN

Gasdermin-E

0.395

MPP9_HUMAN

M-phase phosphoprotein 9

0.395

SLAI1_HUMAN

SLAIN motif-containing protein 1

0.395

I17RD_HUMAN

Interleukin-17 receptor D

0.397

HPLN1_HUMAN

Hyaluronan and proteoglycan link protein 1

0.397

PJVK_HUMAN

Pejvakin

0.397

ENDD1_HUMAN

Endonuclease domain-containing 1 protein

0.397

CASC4_HUMAN

Protein CASC4

0.397

M3K14_HUMAN

Mitogen-activated protein kinase kinase kinase 14

0.397

HAUS8_HUMAN

HAUS augmin-like complex subunit 8

0.397

SELN_HUMAN

Selenoprotein N

0.397

C8AP2_HUMAN

CASP8-associated protein 2

0.399

CA074_HUMAN

UPF0739 protein C1orf74

0.399

ZN507_HUMAN

Zinc finger protein 507

0.399

GSE1_HUMAN

Genetic suppressor element 1

0.399

PARI_HUMAN

PCNA-interacting partner

0.399

SPAT7_HUMAN

Spermatogenesis-associated protein 7

0.399

TM168_HUMAN

Transmembrane protein 168

0.399

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 24 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy