CU062_HUMAN 2019

Gene Name CU062

Description Uncharacterized protein C21orf62

Length 219

9606

Sequence

>sp|Q9NYP8|CU062_HUMAN Uncharacterized protein C21orf62
MAPPSRHCLLLISTLGVFALNCFTKGQKNSTLIFTRENTIRNCSCSADIRDCDYSLANLMCNCKTVLPLAVERTSYNGHLTIWFTDTSALGHLLNFTLVQDLKLSLCSTNTLPTEYLAICGLKRLRINMEAKHPFPEQSLLIHSGGDSDSREKPMWLHKGWQPCMYISFLDMALFNRDSAFKSYSIENVTSIANNFPDFSYFRTFPMPSNKSYVVTFIY

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

PPR26_HUMAN

Protein phosphatase 1 regulatory subunit 26

0.250

LRIF1_HUMAN

Ligand-dependent nuclear receptor-interacting factor 1

0.250

CC122_HUMAN

Coiled-coil domain-containing protein 122

0.250

CEFIP_HUMAN

Cardiac-enriched FHL2-interacting protein

0.250

CD3E_HUMAN

T-cell surface glycoprotein CD3 epsilon chain

0.250

APLD1_HUMAN

Apolipoprotein L domain-containing protein 1

0.250

BCLA3_HUMAN

BCLAF1 and THRAP3 family member 3

0.250

KCNE2_HUMAN

Potassium voltage-gated channel subfamily E member 2

0.250

NOBOX_HUMAN

Homeobox protein NOBOX

0.250

CD40L_HUMAN

CD40 ligand

0.258

UIF_HUMAN

UAP56-interacting factor

0.343

C1QA_HUMAN

Complement C1q subcomponent subunit A

0.343

PRSR2_HUMAN

Proline and serine-rich protein 2

0.343

ASPN_HUMAN

Asporin

0.343

TM159_HUMAN

Promethin

0.343

IL1R2_HUMAN

Interleukin-1 receptor type 2

0.343

MLIP_HUMAN

Muscular LMNA-interacting protein

0.343

T3JAM_HUMAN

TRAF3-interacting JNK-activating modulator

0.343

LYVE1_HUMAN

Lymphatic vessel endothelial hyaluronic acid receptor 1

0.343

MANS1_HUMAN

MANSC domain-containing protein 1

0.343

PD1L1_HUMAN

Programmed cell death 1 ligand 1

0.343

VSIG1_HUMAN

V-set and immunoglobulin domain-containing protein 1

0.343

ILDR2_HUMAN

Immunoglobulin-like domain-containing receptor 2

0.343

ZN750_HUMAN

Zinc finger protein 750

0.343

ETAA1_HUMAN

Ewings tumor-associated antigen 1

0.343

TCFL5_HUMAN

Transcription factor-like 5 protein

0.343

GLHA_HUMAN

Glycoprotein hormones alpha chain

0.343

CCGL_HUMAN

Voltage-dependent calcium channel gamma-like subunit

0.343

FETUA_HUMAN

Alpha-2-HS-glycoprotein

0.343

VSI10_HUMAN

V-set and immunoglobulin domain-containing protein 10

0.343

LRC19_HUMAN

Leucine-rich repeat-containing protein 19

0.343

PALB2_HUMAN

Partner and localizer of BRCA2

0.343

CAHM3_HUMAN

Calcium homeostasis modulator protein 3

0.343

PTX3_HUMAN

Pentraxin-related protein PTX3

0.343

FA83A_HUMAN

Protein FAM83A

0.343

ZN365_HUMAN

Protein ZNF365

0.343

COX7B_HUMAN

Cytochrome c oxidase subunit 7B, mitochondrial

0.343

IL6_HUMAN

Interleukin-6

0.354

PRR29_HUMAN

Proline-rich protein 29

0.354

MAMD1_HUMAN

Mastermind-like domain-containing protein 1

0.354

CD6_HUMAN

T-cell differentiation antigen CD6

0.354

CENPU_HUMAN

Centromere protein U

0.354

HHLA1_HUMAN

HERV-H LTR-associating protein 1

0.354

INY2B_HUMAN

Protein INSYN2B

0.354

P2Y14_HUMAN

P2Y purinoceptor 14

0.354

FETA_HUMAN

Alpha-fetoprotein

0.365

IGSF6_HUMAN

Immunoglobulin superfamily member 6

0.365

ZBTB6_HUMAN

Zinc finger and BTB domain-containing protein 6

0.365

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

GLHA_HUMAN

Glycoprotein hormones alpha chain

0.341

PD1L1_HUMAN

Programmed cell death 1 ligand 1

0.369

CC122_HUMAN

Coiled-coil domain-containing protein 122

0.374

BCLA3_HUMAN

BCLAF1 and THRAP3 family member 3

0.378

MAMD1_HUMAN

Mastermind-like domain-containing protein 1

0.380

CMGA_HUMAN

Chromogranin-A

0.382

ZN652_HUMAN

Zinc finger protein 652

0.382

F222B_HUMAN

Protein FAM222B

0.382

UIF_HUMAN

UAP56-interacting factor

0.382

ZBT20_HUMAN

Zinc finger and BTB domain-containing protein 20

0.382

ZBT25_HUMAN

Zinc finger and BTB domain-containing protein 25

0.384

TAC2N_HUMAN

Tandem C2 domains nuclear protein

0.384

SMPX_HUMAN

Small muscular protein

0.384

NOBOX_HUMAN

Homeobox protein NOBOX

0.387

MLIP_HUMAN

Muscular LMNA-interacting protein

0.387

CD3E_HUMAN

T-cell surface glycoprotein CD3 epsilon chain

0.389

MNARL_HUMAN

Major intrinsically disordered NOTCH2-binding receptor 1-like

0.389

CE030_HUMAN

UNC119-binding protein C5orf30

0.389

ZN365_HUMAN

Protein ZNF365

0.389

F1892_HUMAN

Protein FAM189A2

0.391

SYT13_HUMAN

Synaptotagmin-13

0.391

CCGL_HUMAN

Voltage-dependent calcium channel gamma-like subunit

0.393

ERMIN_HUMAN

Ermin

0.393

ZN335_HUMAN

Zinc finger protein 335

0.394

LGI2_HUMAN

Leucine-rich repeat LGI family member 2

0.394

LGI1_HUMAN

Leucine-rich glioma-inactivated protein 1

0.394

TANK_HUMAN

TRAF family member-associated NF-kappa-B activator

0.394

AKA11_HUMAN

A-kinase anchor protein 11

0.394

CLD11_HUMAN

Claudin-11

0.394

NYAP2_HUMAN

Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2

0.394

ZBTB1_HUMAN

Zinc finger and BTB domain-containing protein 1

0.394

PHAG1_HUMAN

Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

0.394

CCSE2_HUMAN

Serine-rich coiled-coil domain-containing protein 2

0.394

GDNF_HUMAN

Glial cell line-derived neurotrophic factor

0.394

ZBT18_HUMAN

Zinc finger and BTB domain-containing protein 18

0.394

CCR7_HUMAN

C-C chemokine receptor type 7

0.394

LUR1L_HUMAN

Leucine rich adaptor protein 1-like

0.394

FMOD_HUMAN

Fibromodulin

0.394

VCAM1_HUMAN

Vascular cell adhesion protein 1

0.394

NLRX1_HUMAN

NLR family member X1

0.394

MBP_HUMAN

Myelin basic protein

0.394

PALMD_HUMAN

Palmdelphin

0.394

SKA3_HUMAN

Spindle and kinetochore-associated protein 3

0.394

CXD2_HUMAN

Gap junction delta-2 protein

0.394

CKLF3_HUMAN

CKLF-like MARVEL transmembrane domain-containing protein 3

0.394

ANGT_HUMAN

Angiotensinogen

0.394

LEPR_HUMAN

Leptin receptor

0.394

AZI2_HUMAN

5-azacytidine-induced protein 2

0.394

CD40L_HUMAN

CD40 ligand

0.396

DCSTP_HUMAN

Dendritic cell-specific transmembrane protein

0.397

CXL14_HUMAN

C-X-C motif chemokine 14

0.397

K1671_HUMAN

Uncharacterized protein KIAA1671

0.397

ZN711_HUMAN

Zinc finger protein 711

0.397

ZBT24_HUMAN

Zinc finger and BTB domain-containing protein 24

0.397

GP149_HUMAN

Probable G-protein coupled receptor 149

0.397

APC16_HUMAN

Anaphase-promoting complex subunit 16

0.397

CAVN4_HUMAN

Caveolae-associated protein 4

0.397

DSG2_HUMAN

Desmoglein-2

0.397

EDN1_HUMAN

Endothelin-1

0.397

ESM1_HUMAN

Endothelial cell-specific molecule 1

0.397

PCD10_HUMAN

Protocadherin-10

0.397

T4S4_HUMAN

Transmembrane 4 L6 family member 4

0.397

LBH_HUMAN

Protein LBH

0.397

SYNCI_HUMAN

Syncoilin

0.397

MA7D2_HUMAN

MAP7 domain-containing protein 2

0.397

CA052_HUMAN

UPF0690 protein C1orf52

0.399

LYVE1_HUMAN

Lymphatic vessel endothelial hyaluronic acid receptor 1

0.399

PKHO1_HUMAN

Pleckstrin homology domain-containing family O member 1

0.399

PCD12_HUMAN

Protocadherin-12

0.399

ZN638_HUMAN

Zinc finger protein 638

0.399

GEMC1_HUMAN

Geminin coiled-coil domain-containing protein 1

0.399

SCAR3_HUMAN

Scavenger receptor class A member 3

0.399

TM114_HUMAN

Transmembrane protein 114

0.399

CX021_HUMAN

Uncharacterized protein CXorf21

0.399

PRSR2_HUMAN

Proline and serine-rich protein 2

0.399

CEP68_HUMAN

Centrosomal protein of 68 kDa

0.399

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 15 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy