CADH7_HUMAN 2019

Gene Name CADH7

Description Cadherin-7

Length 785

9606

Sequence

>sp|Q9ULB5|CADH7_HUMAN Cadherin-7
MKLGKVEFCHFLQLIALFLCFSGMSQAELSRSRSKPYFQSGRSRTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGASSIFIIDENTGDIHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYTAGVPEMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQPYFSVEPKTGVIKTALPNMDREAKDQYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPESLPVASVVARIKAADADIGANAEMEYKIVDGDGLGIFKISVDKETQEGIITIQKELDFEAKTSYTLRIEAANKDADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEATQVGNIIGTVAAHDPDSSNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRETNAIHNITVLAMESQNPSQVGRGYVAITILDINDNAPEFAMDYETTVCENAQPGQVIQKISAVDKDEPSNGHQFYFSLTTDATNNHNFSLKDNKDNTASILTRRNGFRRQEQSVYYLPIFIVDSGSPSLSSTNTLTIRVCDCDADGVAQTCNAEAYVLPAGLSTGALIAILACVLTLLVLILLIVTMRRRKKEPLIFDEERDIRENIVRYDDEGGGEEDTEAFDMAALRNLNVIRDTKTRRDVTPEIQFLSRPAFKSIPDNVIFREFIWERLKEADVDPGAPPYDSLQTYAFEGNGSVAESLSSLDSISSNSDQNYDYLSDWGPRFKRLADMYGTGQESLYS

Domains

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Help

What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

CAD12_HUMAN

Cadherin-12

0.000

CADH4_HUMAN

Cadherin-4

0.000

CADH2_HUMAN

Cadherin-2

0.209

CAD11_HUMAN

Cadherin-11

0.209

CADH6_HUMAN

Cadherin-6

0.209

CADH1_HUMAN

Cadherin-1

0.213

CAD15_HUMAN

Cadherin-15

0.295

IKZF1_HUMAN

DNA-binding protein Ikaros

0.302

TLR5_HUMAN

Toll-like receptor 5

0.354

FLRT2_HUMAN

Leucine-rich repeat transmembrane protein FLRT2

0.361

ZBT44_HUMAN

Zinc finger and BTB domain-containing protein 44

0.361

IKZF2_HUMAN

Zinc finger protein Helios

0.361

TNNC1_HUMAN

Troponin C, slow skeletal and cardiac muscles

0.361

CXB1_HUMAN

Gap junction beta-1 protein

0.361

CXA1_HUMAN

Gap junction alpha-1 protein

0.361

FABPL_HUMAN

Fatty acid-binding protein, liver

0.361

CXA10_HUMAN

Gap junction alpha-10 protein

0.361

FABP6_HUMAN

Gastrotropin

0.361

CXA8_HUMAN

Gap junction alpha-8 protein

0.361

CAD18_HUMAN

Cadherin-18

0.361

CAD20_HUMAN

Cadherin-20

0.361

CLD10_HUMAN

Claudin-10

0.361

TM121_HUMAN

Transmembrane protein 121

0.361

CAD10_HUMAN

Cadherin-10

0.361

CADH8_HUMAN

Cadherin-8

0.361

MYPC1_HUMAN

Myosin-binding protein C, slow-type

0.361

CLD8_HUMAN

Claudin-8

0.361

MYPC3_HUMAN

Myosin-binding protein C, cardiac-type

0.361

CXG1_HUMAN

Gap junction gamma-1 protein

0.361

CLTRN_HUMAN

Collectrin

0.369

CLD1_HUMAN

Claudin-1

0.369

CLDN1_HUMAN

Claudin domain-containing protein 1

0.400

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

CAD11_HUMAN

Cadherin-11

0.305

CADH2_HUMAN

Cadherin-2

0.321

FABP6_HUMAN

Gastrotropin

0.339

CXB1_HUMAN

Gap junction beta-1 protein

0.339

CAD12_HUMAN

Cadherin-12

0.342

NECT1_HUMAN

Nectin-1

0.352

CADH1_HUMAN

Cadherin-1

0.354

CLD10_HUMAN

Claudin-10

0.355

MAL2_HUMAN

Protein MAL2

0.357

BORG2_HUMAN

Cdc42 effector protein 3

0.366

STXB6_HUMAN

Syntaxin-binding protein 6

0.366

ZBT44_HUMAN

Zinc finger and BTB domain-containing protein 44

0.366

JAM3_HUMAN

Junctional adhesion molecule C

0.368

CAD10_HUMAN

Cadherin-10

0.368

MYPC3_HUMAN

Myosin-binding protein C, cardiac-type

0.368

GTF2I_HUMAN

General transcription factor II-I

0.370

PEPL_HUMAN

Periplakin

0.370

ZBT20_HUMAN

Zinc finger and BTB domain-containing protein 20

0.370

NEXN_HUMAN

Nexilin

0.378

FABPL_HUMAN

Fatty acid-binding protein, liver

0.378

PROS_HUMAN

Vitamin K-dependent protein S

0.380

CXG1_HUMAN

Gap junction gamma-1 protein

0.380

CD166_HUMAN

CD166 antigen

0.380

ZN142_HUMAN

Zinc finger protein 142

0.380

MYPC1_HUMAN

Myosin-binding protein C, slow-type

0.380

CADH6_HUMAN

Cadherin-6

0.380

FBLN7_HUMAN

Fibulin-7

0.380

CEP55_HUMAN

Centrosomal protein of 55 kDa

0.380

IKZF2_HUMAN

Zinc finger protein Helios

0.380

VCAM1_HUMAN

Vascular cell adhesion protein 1

0.382

ZBTB1_HUMAN

Zinc finger and BTB domain-containing protein 1

0.382

CXD2_HUMAN

Gap junction delta-2 protein

0.382

CCR7_HUMAN

C-C chemokine receptor type 7

0.382

CKLF3_HUMAN

CKLF-like MARVEL transmembrane domain-containing protein 3

0.382

LGI1_HUMAN

Leucine-rich glioma-inactivated protein 1

0.382

ITGBL_HUMAN

Integrin beta-like protein 1

0.382

ZN335_HUMAN

Zinc finger protein 335

0.382

ZBT18_HUMAN

Zinc finger and BTB domain-containing protein 18

0.382

FMOD_HUMAN

Fibromodulin

0.382

BFSP1_HUMAN

Filensin

0.382

AZI2_HUMAN

5-azacytidine-induced protein 2

0.382

RAG2_HUMAN

V(D)J recombination-activating protein 2

0.382

CLD11_HUMAN

Claudin-11

0.382

ZN711_HUMAN

Zinc finger protein 711

0.384

GPR39_HUMAN

G-protein coupled receptor 39

0.384

IL12B_HUMAN

Interleukin-12 subunit beta

0.384

AUGN_HUMAN

Augurin

0.384

CR025_HUMAN

Uncharacterized protein C18orf25

0.384

CADH4_HUMAN

Cadherin-4

0.384

ZBT41_HUMAN

Zinc finger and BTB domain-containing protein 41

0.384

ZBT37_HUMAN

Zinc finger and BTB domain-containing protein 37

0.389

IKZF1_HUMAN

DNA-binding protein Ikaros

0.389

PCOC2_HUMAN

Procollagen C-endopeptidase enhancer 2

0.391

STC2_HUMAN

Stanniocalcin-2

0.391

SH3B4_HUMAN

SH3 domain-binding protein 4

0.391

NECT3_HUMAN

Nectin-3

0.391

NFL_HUMAN

Neurofilament light polypeptide

0.391

RIC3_HUMAN

Protein RIC-3

0.391

MFA3L_HUMAN

Microfibrillar-associated protein 3-like

0.393

S1PR3_HUMAN

Sphingosine 1-phosphate receptor 3

0.393

NPY_HUMAN

Pro-neuropeptide Y

0.393

P33MX_HUMAN

Putative monooxygenase p33MONOX

0.393

CBLN4_HUMAN

Cerebellin-4

0.393

ZN131_HUMAN

Zinc finger protein 131

0.393

PEDF_HUMAN

Pigment epithelium-derived factor

0.393

STYK1_HUMAN

Tyrosine-protein kinase STYK1

0.393

LEG1_HUMAN

Galectin-1

0.393

MERB1_HUMAN

bMERB domain-containing protein 1

0.393

CALD1_HUMAN

Caldesmon

0.393

ZBT10_HUMAN

Zinc finger and BTB domain-containing protein 10

0.393

PRL_HUMAN

Prolactin

0.393

PENK_HUMAN

Proenkephalin-A

0.393

FAKD2_HUMAN

FAST kinase domain-containing protein 2, mitochondrial

0.393

OCLN_HUMAN

Occludin

0.393

MYZAP_HUMAN

Myocardial zonula adherens protein

0.393

NEXMI_HUMAN

Neurite extension and migration factor

0.393

ZN644_HUMAN

Zinc finger protein 644

0.393

ADNP_HUMAN

Activity-dependent neuroprotector homeobox protein

0.393

PDGFC_HUMAN

Platelet-derived growth factor C

0.393

CO7_HUMAN

Complement component C7

0.393

CAD20_HUMAN

Cadherin-20

0.393

ZPLD1_HUMAN

Zona pellucida-like domain-containing protein 1

0.393

GHR_HUMAN

Growth hormone receptor

0.393

VSTM4_HUMAN

V-set and transmembrane domain-containing protein 4

0.393

SYBU_HUMAN

Syntabulin

0.393

EPYC_HUMAN

Epiphycan

0.393

CFAI_HUMAN

Complement factor I

0.395

GDF9_HUMAN

Growth/differentiation factor 9

0.395

CAVN2_HUMAN

Caveolae-associated protein 2

0.395

K1107_HUMAN

AP2-interacting clathrin-endocytosis protein

0.395

TSN1_HUMAN

Tetraspanin-1

0.395

OLFM4_HUMAN

Olfactomedin-4

0.395

CCPG1_HUMAN

Cell cycle progression protein 1

0.395

DLK2_HUMAN

Protein delta homolog 2

0.395

ERRFI_HUMAN

ERBB receptor feedback inhibitor 1

0.395

SLIK1_HUMAN

SLIT and NTRK-like protein 1

0.395

APOH_HUMAN

Beta-2-glycoprotein 1

0.395

REST_HUMAN

RE1-silencing transcription factor

0.395

SCF_HUMAN

Kit ligand

0.395

MAL_HUMAN

Myelin and lymphocyte protein

0.395

CMGA_HUMAN

Chromogranin-A

0.395

TRH_HUMAN

Pro-thyrotropin-releasing hormone

0.395

CLTRN_HUMAN

Collectrin

0.395

F222B_HUMAN

Protein FAM222B

0.395

UIF_HUMAN

UAP56-interacting factor

0.395

SLIK6_HUMAN

SLIT and NTRK-like protein 6

0.397

ZBTB5_HUMAN

Zinc finger and BTB domain-containing protein 5

0.397

TCIM_HUMAN

Transcriptional and immune response regulator

0.397

ZBT25_HUMAN

Zinc finger and BTB domain-containing protein 25

0.397

IL10_HUMAN

Interleukin-10

0.397

FLIP1_HUMAN

Filamin-A-interacting protein 1

0.400

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 22 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy