KCNK7_HUMAN 2019

Gene Name KCNK7

Description Potassium channel subfamily K member 7

Length 307

9606

Sequence

>sp|Q9Y2U2|KCNK7_HUMAN Potassium channel subfamily K member 7
MGGLRPWSRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLPASLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVASSFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRGRSLHPVIYHLGQLALLGYLLLGLLAMLLAVETFSELPQVRAMGKFFRPSGPVTAEDQGGILGQDELALSTLPPAAPASGQAPAC

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

GFRA4_HUMAN

GDNF family receptor alpha-4

0.354

ZCH12_HUMAN

Zinc finger CCHC domain-containing protein 12

0.354

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

ZN691_HUMAN

Zinc finger protein 691

0.322

SYNE4_HUMAN

Nesprin-4

0.324

ZNF48_HUMAN

Zinc finger protein 48

0.324

FWCH2_HUMAN

FLYWCH family member 2

0.330

RAGE_HUMAN

Advanced glycosylation end product-specific receptor

0.344

S10A8_HUMAN

Protein S100-A8

0.344

ZN189_HUMAN

Zinc finger protein 189

0.347

G6B_HUMAN

Megakaryocyte and platelet inhibitory receptor G6b

0.347

ZFP1_HUMAN

Zinc finger protein 1 homolog

0.347

DBND2_HUMAN

Dysbindin domain-containing protein 2

0.347

CXL16_HUMAN

C-X-C motif chemokine 16

0.347

CALY_HUMAN

Neuron-specific vesicular protein calcyon

0.350

ZN446_HUMAN

Zinc finger protein 446

0.350

PRCA1_HUMAN

Protein PROCA1

0.350

LY6H_HUMAN

Lymphocyte antigen 6H

0.350

ZN202_HUMAN

Zinc finger protein 202

0.365

LAX1_HUMAN

Lymphocyte transmembrane adapter 1

0.365

PA2GF_HUMAN

Group IIF secretory phospholipase A2

0.365

ZSC20_HUMAN

Zinc finger and SCAN domain-containing protein 20

0.365

SPIN4_HUMAN

Spindlin-4

0.368

CD19_HUMAN

B-lymphocyte antigen CD19

0.368

LAT_HUMAN

Linker for activation of T-cells family member 1

0.368

IL2_HUMAN

Interleukin-2

0.368

TNF18_HUMAN

Tumor necrosis factor ligand superfamily member 18

0.368

CSF2_HUMAN

Granulocyte-macrophage colony-stimulating factor

0.368

DKKL1_HUMAN

Dickkopf-like protein 1

0.368

ZSC25_HUMAN

Zinc finger and SCAN domain-containing protein 25

0.371

BPIA3_HUMAN

BPI fold-containing family A member 3

0.371

F209A_HUMAN

Protein FAM209A

0.371

ZN445_HUMAN

Zinc finger protein 445

0.371

ZN174_HUMAN

Zinc finger protein 174

0.371

TRIMM_HUMAN

Probable E3 ubiquitin-protein ligase TRIML2

0.371

IRGQ_HUMAN

Immunity-related GTPase family Q protein

0.371

IL13_HUMAN

Interleukin-13

0.371

CLD9_HUMAN

Claudin-9

0.371

BEX3_HUMAN

Protein BEX3

0.371

IL33_HUMAN

Interleukin-33

0.371

ETV2_HUMAN

ETS translocation variant 2

0.371

ONCM_HUMAN

Oncostatin-M

0.375

IZUM4_HUMAN

Izumo sperm-egg fusion protein 4

0.375

CI131_HUMAN

Uncharacterized protein C9orf131

0.375

F71E1_HUMAN

Protein FAM71E1

0.378

MSTRO_HUMAN

Protein maestro

0.384

GPC5D_HUMAN

G-protein coupled receptor family C group 5 member D

0.384

SPNDC_HUMAN

Spindlin interactor and repressor of chromatin-binding protein

0.384

IL27A_HUMAN

Interleukin-27 subunit alpha

0.384

CQ080_HUMAN

Uncharacterized protein C17orf80

0.387

ZN205_HUMAN

Zinc finger protein 205

0.387

ZKSC2_HUMAN

Zinc finger protein with KRAB and SCAN domains 2

0.387

ZKSC5_HUMAN

Zinc finger protein with KRAB and SCAN domains 5

0.387

CC196_HUMAN

Putative coiled-coil domain-containing protein 196

0.387

IL1A_HUMAN

Interleukin-1 alpha

0.387

TM219_HUMAN

Insulin-like growth factor-binding protein 3 receptor

0.387

RTBDN_HUMAN

Retbindin

0.387

OPALI_HUMAN

Opalin

0.391

CC116_HUMAN

Coiled-coil domain-containing protein 116

0.391

T126B_HUMAN

Complex I assembly factor TMEM126B, mitochondrial

0.391

NGAL_HUMAN

Neutrophil gelatinase-associated lipocalin

0.391

F170A_HUMAN

Protein FAM170A

0.391

ZN449_HUMAN

Zinc finger protein 449

0.391

TRML2_HUMAN

Trem-like transcript 2 protein

0.391

ZN263_HUMAN

Zinc finger protein 263

0.391

SHRM1_HUMAN

Protein Shroom1

0.391

PRR3_HUMAN

Proline-rich protein 3

0.391

LY66F_HUMAN

Lymphocyte antigen 6 complex locus protein G6f

0.391

CP090_HUMAN

Uncharacterized protein C16orf90

0.391

ZKSC8_HUMAN

Zinc finger protein with KRAB and SCAN domains 8

0.394

PRS58_HUMAN

Serine protease 58

0.394

CE046_HUMAN

Uncharacterized protein C5orf46

0.394

ZCCHL_HUMAN

Zinc finger CCCH-type antiviral protein 1-like

0.394

HDBP1_HUMAN

Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

0.394

LY66C_HUMAN

Lymphocyte antigen 6 complex locus protein G6c

0.394

TCAL8_HUMAN

Transcription elongation factor A protein-like 8

0.394

NNAT_HUMAN

Neuronatin

0.394

CD320_HUMAN

CD320 antigen

0.394

FLT3L_HUMAN

Fms-related tyrosine kinase 3 ligand

0.394

MRGRF_HUMAN

Mas-related G-protein coupled receptor member F

0.394

RBAK_HUMAN

RB-associated KRAB zinc finger protein

0.397

ZFP90_HUMAN

Zinc finger protein 90 homolog

0.397

A7L3B_HUMAN

Ataxin-7-like protein 3B

0.397

CK071_HUMAN

Uncharacterized protein C11orf71

0.397

LY65C_HUMAN

Lymphocyte antigen 6 complex locus protein G5c

0.397

ERIC4_HUMAN

Glutamate-rich protein 4

0.397

CD177_HUMAN

CD177 antigen

0.397

ENHO_HUMAN

Adropin

0.397

LYPD4_HUMAN

Ly6/PLAUR domain-containing protein 4

0.397

ZNF23_HUMAN

Zinc finger protein 23

0.397

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 7 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy