RAB6D_HUMAN 2019

Gene Name RAB6D

Description Ras-related protein Rab-6D

Length 254

9606

Sequence

>sp|Q53S08|RAB6D_HUMAN Ras-related protein Rab-6D
MSAGGDFGNPLRKFKLVFLGEQSVAKTSLITRFRYDSFDNTYQAIIGIDFLSKTMYLEDGTIGLRLWDTAGQERLRSLIPRYIRDSAAAVVVYDITNVNSFQQTTKWIDDVRTEGGSDVIITLVGNKTDLADKRQVSIEEGERKAKGLNVTFIETRAKAGYNVKQLFRRVAAALPGMESTQDGSREDMSDIKLEKPQEQTVSEGGCSCYSPMSSSTLPQKPPYSFIDCSVNIGLNLFPSLITFCNSSLLPVSWR

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

RAB6C_HUMAN

Ras-related protein Rab-6C

0.091

CLH2_HUMAN

Clathrin heavy chain 2

0.394

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

RAB6C_HUMAN

Ras-related protein Rab-6C

0.051

PRPS3_HUMAN

Ribose-phosphate pyrophosphokinase 3

0.343

TBA3E_HUMAN

Tubulin alpha-3E chain

0.346

I3L4J1_HUMAN

Uncharacterized protein (Fragment)

0.347

RS4Y2_HUMAN

40S ribosomal protein S4, Y isoform 2

0.350

AG1L2_HUMAN

Putative glycosyltransferase ALG1L2

0.352

UE2NL_HUMAN

Putative ubiquitin-conjugating enzyme E2 N-like

0.356

P4R3C_HUMAN

Protein PPP4R3C

0.357

PAPOB_HUMAN

Poly(A) polymerase beta

0.358

RAB6B_HUMAN

Ras-related protein Rab-6B

0.360

CLH2_HUMAN

Clathrin heavy chain 2

0.361

TOP1M_HUMAN

DNA topoisomerase I, mitochondrial

0.361

RS4Y1_HUMAN

40S ribosomal protein S4, Y isoform 1

0.361

H2BFS_HUMAN

Histone H2B type F-S

0.363

RAB6A_HUMAN

Ras-related protein Rab-6A

0.364

IF2GL_HUMAN

Eukaryotic translation initiation factor 2 subunit 3B

0.370

H2B1L_HUMAN

Histone H2B type 1-L

0.371

ADT4_HUMAN

ADP/ATP translocase 4

0.373

IF5AL_HUMAN

Eukaryotic translation initiation factor 5A-1-like

0.375

H2A1J_HUMAN

Histone H2A type 1-J

0.376

RPB1B_HUMAN

DNA-directed RNA polymerase II subunit RPB11-b1

0.376

H2B1M_HUMAN

Histone H2B type 1-M

0.376

RPB1C_HUMAN

DNA-directed RNA polymerase II subunit RPB11-b2

0.377

H2B1O_HUMAN

Histone H2B type 1-O

0.377

CANB2_HUMAN

Calcineurin subunit B type 2

0.378

DDX3Y_HUMAN

ATP-dependent RNA helicase DDX3Y

0.380

RS26L_HUMAN

Putative 40S ribosomal protein S26-like 1

0.380

H2B1H_HUMAN

Histone H2B type 1-H

0.380

TCPW_HUMAN

T-complex protein 1 subunit zeta-2

0.381

H2A1H_HUMAN

Histone H2A type 1-H

0.381

CERS4_HUMAN

Ceramide synthase 4

0.381

TKTL1_HUMAN

Transketolase-like protein 1

0.382

KDM5D_HUMAN

Lysine-specific demethylase 5D

0.382

H2B1N_HUMAN

Histone H2B type 1-N

0.382

ADT3_HUMAN

ADP/ATP translocase 3

0.384

H2B1J_HUMAN

Histone H2B type 1-J

0.384

NAA16_HUMAN

N-alpha-acetyltransferase 16, NatA auxiliary subunit

0.384

CSK23_HUMAN

Casein kinase II subunit alpha 3

0.385

H2A1A_HUMAN

Histone H2A type 1-A

0.386

H2A1D_HUMAN

Histone H2A type 1-D

0.386

TBA1C_HUMAN

Tubulin alpha-1C chain

0.387

NCB2L_HUMAN

Nuclear cap-binding protein subunit 2-like

0.387

SC11B_HUMAN

Putative signal peptidase complex catalytic subunit SEC11B

0.387

PABP3_HUMAN

Polyadenylate-binding protein 3

0.387

PIPSL_HUMAN

Putative PIP5K1A and PSMD4-like protein

0.388

NP1L2_HUMAN

Nucleosome assembly protein 1-like 2

0.388

RL37L_HUMAN

Putative 60S ribosomal protein L37a-like protein

0.388

VATC2_HUMAN

V-type proton ATPase subunit C 2

0.389

NACA2_HUMAN

Nascent polypeptide-associated complex subunit alpha-2

0.389

RLA0L_HUMAN

60S acidic ribosomal protein P0-like

0.389

TBB2A_HUMAN

Tubulin beta-2A chain

0.390

VATE2_HUMAN

V-type proton ATPase subunit E 2

0.390

MRP2_HUMAN

Canalicular multispecific organic anion transporter 1

0.390

TKTL2_HUMAN

Transketolase-like protein 2

0.391

COPG1_HUMAN

Coatomer subunit gamma-1

0.391

IF1AY_HUMAN

Eukaryotic translation initiation factor 1A, Y-chromosomal

0.392

DNPEP_HUMAN

Aspartyl aminopeptidase

0.392

H2B1K_HUMAN

Histone H2B type 1-K

0.392

QCR1_HUMAN

Cytochrome b-c1 complex subunit 1, mitochondrial

0.392

A0A1W2PQ64_HUMAN

SSU72 pseudogene 5

0.392

TV23C_HUMAN

Golgi apparatus membrane protein TVP23 homolog C

0.392

AP1G2_HUMAN

AP-1 complex subunit gamma-like 2

0.393

CC50B_HUMAN

Cell cycle control protein 50B

0.393

IDI2_HUMAN

Isopentenyl-diphosphate delta-isomerase 2

0.393

S61A2_HUMAN

Protein transport protein Sec61 subunit alpha isoform 2

0.393

H2B1A_HUMAN

Histone H2B type 1-A

0.393

A0A1W2PR75_HUMAN

SSU72 pseudogene 8

0.394

HDAC1_HUMAN

Histone deacetylase 1

0.394

H2AX_HUMAN

Histone H2AX

0.394

ERD21_HUMAN

ER lumen protein-retaining receptor 1

0.394

H2AJ_HUMAN

Histone H2A.J

0.394

PRPS2_HUMAN

Ribose-phosphate pyrophosphokinase 2

0.395

TBA1B_HUMAN

Tubulin alpha-1B chain

0.395

RBBP7_HUMAN

Histone-binding protein RBBP7

0.395

PGK2_HUMAN

Phosphoglycerate kinase 2

0.396

A0A1W2PQ27_HUMAN

SSU72 pseudogene 7

0.396

A0A1W2PQJ5_HUMAN

SSU72 pseudogene 3

0.396

R113B_HUMAN

RING finger protein 113B

0.397

H2A3_HUMAN

Histone H2A type 3

0.397

H2A1C_HUMAN

Histone H2A type 1-C

0.397

A0A1B0GUL7_HUMAN

Uncharacterized protein

0.397

ADT1_HUMAN

ADP/ATP translocase 1

0.397

H2A1_HUMAN

Histone H2A type 1

0.397

A0A1W2PQC6_HUMAN

SSU72 pseudogene 4

0.398

A0A1W2PQD8_HUMAN

SSU72 pseudogene 2

0.398

VPP4_HUMAN

V-type proton ATPase 116 kDa subunit a isoform 4

0.398

TBB2B_HUMAN

Tubulin beta-2B chain

0.398

H2B1D_HUMAN

Histone H2B type 1-D

0.398

ALAT1_HUMAN

Alanine aminotransferase 1

0.398

GSK3A_HUMAN

Glycogen synthase kinase-3 alpha

0.398

AP1M2_HUMAN

AP-1 complex subunit mu-2

0.398

TBB4A_HUMAN

Tubulin beta-4A chain

0.399

CERS3_HUMAN

Ceramide synthase 3

0.399

EF1A3_HUMAN

Putative elongation factor 1-alpha-like 3

0.399

S14L6_HUMAN

Putative SEC14-like protein 6

0.399

NACAM_HUMAN

Nascent polypeptide-associated complex subunit alpha, muscle-specific form

0.400

H2A2C_HUMAN

Histone H2A type 2-C

0.400

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 121 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy