RAB6C_HUMAN 2019

Gene Name RAB6C

Description Ras-related protein Rab-6C

Length 254

9606

Sequence

>sp|Q9H0N0|RAB6C_HUMAN Ras-related protein Rab-6C
MSAGGDFGNPLRKFKLVFLGEQSVAKTSLITRFRYDSFDNTYQAIIGIDFLSKTMYLEDGTIGLRLWDTAGQERLRSLIPRYIRDSAAAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIITLVGNRTDLADKRQVSVEEGERKAKGLNVTFIETRAKAGYNVKQLFRRVAAALPGMESTQDGSREDMSDIKLEKPQEQTVSEGGCSCYSPMSSSTLPQKPPYSFIDCSVNIGLNLFPSLITFCNSSLLPVSWR

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

RAB6D_HUMAN

Ras-related protein Rab-6D

0.091

H2A1J_HUMAN

Histone H2A type 1-J

0.400

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

RAB6D_HUMAN

Ras-related protein Rab-6D

0.051

PRPS3_HUMAN

Ribose-phosphate pyrophosphokinase 3

0.340

I3L4J1_HUMAN

Uncharacterized protein (Fragment)

0.344

RS4Y2_HUMAN

40S ribosomal protein S4, Y isoform 2

0.347

TBA3E_HUMAN

Tubulin alpha-3E chain

0.349

AG1L2_HUMAN

Putative glycosyltransferase ALG1L2

0.352

UE2NL_HUMAN

Putative ubiquitin-conjugating enzyme E2 N-like

0.352

PAPOB_HUMAN

Poly(A) polymerase beta

0.354

RAB6B_HUMAN

Ras-related protein Rab-6B

0.357

P4R3C_HUMAN

Protein PPP4R3C

0.357

TOP1M_HUMAN

DNA topoisomerase I, mitochondrial

0.358

RS4Y1_HUMAN

40S ribosomal protein S4, Y isoform 1

0.358

H2BFS_HUMAN

Histone H2B type F-S

0.360

CLH2_HUMAN

Clathrin heavy chain 2

0.361

RAB6A_HUMAN

Ras-related protein Rab-6A

0.361

IF2GL_HUMAN

Eukaryotic translation initiation factor 2 subunit 3B

0.367

H2B1L_HUMAN

Histone H2B type 1-L

0.368

IF5AL_HUMAN

Eukaryotic translation initiation factor 5A-1-like

0.372

H2A1J_HUMAN

Histone H2A type 1-J

0.373

RPB1B_HUMAN

DNA-directed RNA polymerase II subunit RPB11-b1

0.373

H2B1M_HUMAN

Histone H2B type 1-M

0.373

RPB1C_HUMAN

DNA-directed RNA polymerase II subunit RPB11-b2

0.374

H2B1O_HUMAN

Histone H2B type 1-O

0.374

ADT4_HUMAN

ADP/ATP translocase 4

0.376

RS26L_HUMAN

Putative 40S ribosomal protein S26-like 1

0.377

DDX3Y_HUMAN

ATP-dependent RNA helicase DDX3Y

0.377

H2B1H_HUMAN

Histone H2B type 1-H

0.377

TCPW_HUMAN

T-complex protein 1 subunit zeta-2

0.378

H2A1H_HUMAN

Histone H2A type 1-H

0.378

H2B1N_HUMAN

Histone H2B type 1-N

0.379

ADT3_HUMAN

ADP/ATP translocase 3

0.381

H2B1J_HUMAN

Histone H2B type 1-J

0.381

CANB2_HUMAN

Calcineurin subunit B type 2

0.381

CERS4_HUMAN

Ceramide synthase 4

0.381

NAA16_HUMAN

N-alpha-acetyltransferase 16, NatA auxiliary subunit

0.381

KDM5D_HUMAN

Lysine-specific demethylase 5D

0.382

TKTL1_HUMAN

Transketolase-like protein 1

0.382

CSK23_HUMAN

Casein kinase II subunit alpha 3

0.382

H2A1A_HUMAN

Histone H2A type 1-A

0.383

H2A1D_HUMAN

Histone H2A type 1-D

0.383

PABP3_HUMAN

Polyadenylate-binding protein 3

0.384

PIPSL_HUMAN

Putative PIP5K1A and PSMD4-like protein

0.385

RL37L_HUMAN

Putative 60S ribosomal protein L37a-like protein

0.385

NACA2_HUMAN

Nascent polypeptide-associated complex subunit alpha-2

0.386

TBA1C_HUMAN

Tubulin alpha-1C chain

0.386

RLA0L_HUMAN

60S acidic ribosomal protein P0-like

0.386

VATE2_HUMAN

V-type proton ATPase subunit E 2

0.387

NP1L2_HUMAN

Nucleosome assembly protein 1-like 2

0.388

TKTL2_HUMAN

Transketolase-like protein 2

0.388

COPG1_HUMAN

Coatomer subunit gamma-1

0.388

VATC2_HUMAN

V-type proton ATPase subunit C 2

0.388

IF1AY_HUMAN

Eukaryotic translation initiation factor 1A, Y-chromosomal

0.389

H2B1K_HUMAN

Histone H2B type 1-K

0.389

A0A1W2PQ64_HUMAN

SSU72 pseudogene 5

0.389

NCB2L_HUMAN

Nuclear cap-binding protein subunit 2-like

0.389

SC11B_HUMAN

Putative signal peptidase complex catalytic subunit SEC11B

0.390

IDI2_HUMAN

Isopentenyl-diphosphate delta-isomerase 2

0.390

CC50B_HUMAN

Cell cycle control protein 50B

0.390

H2B1A_HUMAN

Histone H2B type 1-A

0.391

S61A2_HUMAN

Protein transport protein Sec61 subunit alpha isoform 2

0.391

A0A1W2PR75_HUMAN

SSU72 pseudogene 8

0.391

ERD21_HUMAN

ER lumen protein-retaining receptor 1

0.391

H2AX_HUMAN

Histone H2AX

0.391

H2AJ_HUMAN

Histone H2A.J

0.391

PRPS2_HUMAN

Ribose-phosphate pyrophosphokinase 2

0.392

TBA1B_HUMAN

Tubulin alpha-1B chain

0.392

TV23C_HUMAN

Golgi apparatus membrane protein TVP23 homolog C

0.392

MRP2_HUMAN

Canalicular multispecific organic anion transporter 1

0.392

TBB2A_HUMAN

Tubulin beta-2A chain

0.392

AP1G2_HUMAN

AP-1 complex subunit gamma-like 2

0.393

PGK2_HUMAN

Phosphoglycerate kinase 2

0.393

A0A1W2PQJ5_HUMAN

SSU72 pseudogene 3

0.393

A0A1W2PQ27_HUMAN

SSU72 pseudogene 7

0.393

R113B_HUMAN

RING finger protein 113B

0.394

HDAC1_HUMAN

Histone deacetylase 1

0.394

H2A3_HUMAN

Histone H2A type 3

0.394

H2A1C_HUMAN

Histone H2A type 1-C

0.394

A0A1B0GUL7_HUMAN

Uncharacterized protein

0.394

ADT1_HUMAN

ADP/ATP translocase 1

0.394

DNPEP_HUMAN

Aspartyl aminopeptidase

0.394

H2A1_HUMAN

Histone H2A type 1

0.395

A0A1W2PQC6_HUMAN

SSU72 pseudogene 4

0.395

A0A1W2PQD8_HUMAN

SSU72 pseudogene 2

0.395

QCR1_HUMAN

Cytochrome b-c1 complex subunit 1, mitochondrial

0.395

H2B1D_HUMAN

Histone H2B type 1-D

0.395

RBBP7_HUMAN

Histone-binding protein RBBP7

0.395

GSK3A_HUMAN

Glycogen synthase kinase-3 alpha

0.395

ALAT1_HUMAN

Alanine aminotransferase 1

0.395

TBB4A_HUMAN

Tubulin beta-4A chain

0.396

EF1A3_HUMAN

Putative elongation factor 1-alpha-like 3

0.396

NACAM_HUMAN

Nascent polypeptide-associated complex subunit alpha, muscle-specific form

0.397

H2A2C_HUMAN

Histone H2A type 2-C

0.397

VPP4_HUMAN

V-type proton ATPase 116 kDa subunit a isoform 4

0.397

AP1M2_HUMAN

AP-1 complex subunit mu-2

0.398

ERF3A_HUMAN

Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

0.398

KPYR_HUMAN

Pyruvate kinase PKLR

0.398

CERS3_HUMAN

Ceramide synthase 3

0.398

H2A1B_HUMAN

Histone H2A type 1-B/E

0.399

GTR14_HUMAN

Solute carrier family 2, facilitated glucose transporter member 14

0.399

COPG2_HUMAN

Coatomer subunit gamma-2

0.399

2AAB_HUMAN

Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

0.400

VATB1_HUMAN

V-type proton ATPase subunit B, kidney isoform

0.400

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 122 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy