TBA3E_HUMAN 2019

Gene Name TBA3E

Description Tubulin alpha-3E chain

Length 450

9606

Sequence

>sp|Q6PEY2|TBA3E_HUMAN Tubulin alpha-3E chain
MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAASNYARGHYTIGKEIVDLVLDRIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYSKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLVHKFDLMYAKWAFVHWYVGEGMEEGEFSEAREDLAALEKDCEEVGVDSVEAEAEEGEAY

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

TBA4A_HUMAN

Tubulin alpha-4A chain

0.309

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

TBA4A_HUMAN

Tubulin alpha-4A chain

0.286

SC11B_HUMAN

Putative signal peptidase complex catalytic subunit SEC11B

0.299

TBA1C_HUMAN

Tubulin alpha-1C chain

0.314

NCB2L_HUMAN

Nuclear cap-binding protein subunit 2-like

0.331

TBB2A_HUMAN

Tubulin beta-2A chain

0.335

CANB2_HUMAN

Calcineurin subunit B type 2

0.336

RS4Y2_HUMAN

40S ribosomal protein S4, Y isoform 2

0.337

TKTL1_HUMAN

Transketolase-like protein 1

0.339

P4R3C_HUMAN

Protein PPP4R3C

0.344

TBB4A_HUMAN

Tubulin beta-4A chain

0.344

PAPOB_HUMAN

Poly(A) polymerase beta

0.345

AG1L2_HUMAN

Putative glycosyltransferase ALG1L2

0.345

RAB6D_HUMAN

Ras-related protein Rab-6D

0.346

RS26L_HUMAN

Putative 40S ribosomal protein S26-like 1

0.349

RAB6C_HUMAN

Ras-related protein Rab-6C

0.349

TBA3C_HUMAN

Tubulin alpha-3C chain

0.349

HSP76_HUMAN

Heat shock 70 kDa protein 6

0.350

RS4Y1_HUMAN

40S ribosomal protein S4, Y isoform 1

0.352

TBA3D_HUMAN

Tubulin alpha-3D chain

0.356

I3L4J1_HUMAN

Uncharacterized protein (Fragment)

0.363

TBB3_HUMAN

Tubulin beta-3 chain

0.363

PRPS3_HUMAN

Ribose-phosphate pyrophosphokinase 3

0.365

H31_HUMAN

Histone H3.1

0.369

RL37L_HUMAN

Putative 60S ribosomal protein L37a-like protein

0.371

TBA8_HUMAN

Tubulin alpha-8 chain

0.371

TBB2B_HUMAN

Tubulin beta-2B chain

0.373

TBB5_HUMAN

Tubulin beta chain

0.375

CLH2_HUMAN

Clathrin heavy chain 2

0.376

NP1L2_HUMAN

Nucleosome assembly protein 1-like 2

0.376

IF2GL_HUMAN

Eukaryotic translation initiation factor 2 subunit 3B

0.378

ADT4_HUMAN

ADP/ATP translocase 4

0.378

TBA1B_HUMAN

Tubulin alpha-1B chain

0.379

VA0D2_HUMAN

V-type proton ATPase subunit d 2

0.380

CERS4_HUMAN

Ceramide synthase 4

0.381

CSK23_HUMAN

Casein kinase II subunit alpha 3

0.382

ERD21_HUMAN

ER lumen protein-retaining receptor 1

0.383

PABP3_HUMAN

Polyadenylate-binding protein 3

0.384

CSK22_HUMAN

Casein kinase II subunit alpha

0.384

RBBP7_HUMAN

Histone-binding protein RBBP7

0.384

CERS3_HUMAN

Ceramide synthase 3

0.385

H2BFS_HUMAN

Histone H2B type F-S

0.386

TBB8_HUMAN

Tubulin beta-8 chain

0.388

TBB6_HUMAN

Tubulin beta-6 chain

0.389

RLA0L_HUMAN

60S acidic ribosomal protein P0-like

0.389

QCR1_HUMAN

Cytochrome b-c1 complex subunit 1, mitochondrial

0.390

PIPSL_HUMAN

Putative PIP5K1A and PSMD4-like protein

0.390

TKTL2_HUMAN

Transketolase-like protein 2

0.391

UE2NL_HUMAN

Putative ubiquitin-conjugating enzyme E2 N-like

0.391

HDAC1_HUMAN

Histone deacetylase 1

0.391

TCPW_HUMAN

T-complex protein 1 subunit zeta-2

0.391

IF5AL_HUMAN

Eukaryotic translation initiation factor 5A-1-like

0.392

VATB1_HUMAN

V-type proton ATPase subunit B, kidney isoform

0.392

TOP1M_HUMAN

DNA topoisomerase I, mitochondrial

0.392

A0A1W2PQ64_HUMAN

SSU72 pseudogene 5

0.392

A0A1W2PQ27_HUMAN

SSU72 pseudogene 7

0.393

A0A1W2PQJ5_HUMAN

SSU72 pseudogene 3

0.393

AK1BF_HUMAN

Aldo-keto reductase family 1 member B15

0.394

A0A1W2PR75_HUMAN

SSU72 pseudogene 8

0.394

H2A1J_HUMAN

Histone H2A type 1-J

0.395

A0A1W2PQC6_HUMAN

SSU72 pseudogene 4

0.395

A0A1W2PQD8_HUMAN

SSU72 pseudogene 2

0.395

TBA1A_HUMAN

Tubulin alpha-1A chain

0.395

TV23C_HUMAN

Golgi apparatus membrane protein TVP23 homolog C

0.395

VPP2_HUMAN

V-type proton ATPase 116 kDa subunit a isoform 2

0.395

VPP3_HUMAN

V-type proton ATPase 116 kDa subunit a isoform 3

0.396

ERF3A_HUMAN

Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

0.396

GTR7_HUMAN

Solute carrier family 2, facilitated glucose transporter member 7

0.397

RL10L_HUMAN

60S ribosomal protein L10-like

0.397

HS71B_HUMAN

Heat shock 70 kDa protein 1B

0.398

HS71A_HUMAN

Heat shock 70 kDa protein 1A

0.398

GSK3A_HUMAN

Glycogen synthase kinase-3 alpha

0.398

AP1M2_HUMAN

AP-1 complex subunit mu-2

0.398

H2B1L_HUMAN

Histone H2B type 1-L

0.398

PAP1L_HUMAN

Polyadenylate-binding protein 1-like

0.399

RPB1C_HUMAN

DNA-directed RNA polymerase II subunit RPB11-b2

0.399

H2A1H_HUMAN

Histone H2A type 1-H

0.400

CHM4P_HUMAN

Putative charged multivesicular body protein 4B-like protein CHMP4BP1

0.400

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 115 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy