ABEC1_HUMAN 2019

Gene Name ABEC1

Description C->U-editing enzyme APOBEC-1

Length 236

9606

Sequence

>sp|P41238|ABEC1_HUMAN C->U-editing enzyme APOBEC-1
MTSEKGPSTGDPTLRRRIEPWEFDVFYDPRELRKEACLLYEIKWGMSRKIWRSSGKNTTNHVEVNFIKKFTSERDFHPSMSCSITWFLSWSPCWECSQAIREFLSRHPGVTLVIYVARLFWHMDQQNRQGLRDLVNSGVTIQIMRASEYYHCWRNFVNYPPGDEAHWPQYPPLWMMLYALELHCIILSLPPCLKISRRWQNHLTFFRLHLQNCHYQTIPPHILLATGLIHPSVAWR

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

TBC21_HUMAN

TBC1 domain family member 21

0.000

DMP1_HUMAN

Dentin matrix acidic phosphoprotein 1

0.000

ACTT2_HUMAN

Actin-related protein T2

0.000

O6C74_HUMAN

Olfactory receptor 6C74

0.000

NKG7_HUMAN

Protein NKG7

0.000

TACT_HUMAN

T-cell surface protein tactile

0.000

PRS54_HUMAN

Inactive serine protease 54

0.000

HPIP_HUMAN

Host cell factor C1 regulator 1

0.000

ARM12_HUMAN

Armadillo repeat-containing protein 12

0.000

CQ064_HUMAN

Uncharacterized protein C17orf64

0.000

OR6C1_HUMAN

Olfactory receptor 6C1

0.000

CC159_HUMAN

Coiled-coil domain-containing protein 159

0.000

PRS53_HUMAN

Serine protease 53

0.000

SMRP1_HUMAN

Spermatid-specific manchette-related protein 1

0.000

AKAP4_HUMAN

A-kinase anchor protein 4

0.000

TM139_HUMAN

Transmembrane protein 139

0.000

IL15_HUMAN

Interleukin-15

0.302

K1C23_HUMAN

Keratin, type I cytoskeletal 23

0.302

MISSL_HUMAN

MAPK-interacting and spindle-stabilizing protein-like

0.302

BASP1_HUMAN

Brain acid soluble protein 1

0.302

CC185_HUMAN

Coiled-coil domain-containing protein 185

0.302

NFAM1_HUMAN

NFAT activation molecule 1

0.302

MROH7_HUMAN

Maestro heat-like repeat-containing protein family member 7

0.302

GSDMA_HUMAN

Gasdermin-A

0.302

CD5_HUMAN

T-cell surface glycoprotein CD5

0.302

ZPBP1_HUMAN

Zona pellucida-binding protein 1

0.302

TB182_HUMAN

182 kDa tankyrase-1-binding protein

0.302

IL9R_HUMAN

Interleukin-9 receptor

0.302

CBY3_HUMAN

Protein chibby homolog 3

0.302

SPERT_HUMAN

Spermatid-associated protein

0.302

FYB2_HUMAN

FYN-binding protein 2

0.302

OSTP_HUMAN

Osteopontin

0.302

GKN2_HUMAN

Gastrokine-2

0.302

M4A15_HUMAN

Membrane-spanning 4-domains subfamily A member 15

0.302

AKAP5_HUMAN

A-kinase anchor protein 5

0.302

CF132_HUMAN

Uncharacterized protein C6orf132

0.302

TNFL8_HUMAN

Tumor necrosis factor ligand superfamily member 8

0.302

IL23R_HUMAN

Interleukin-23 receptor

0.302

MTCP1_HUMAN

Protein p13 MTCP-1

0.302

NPS_HUMAN

Neuropeptide S

0.302

VEXIN_HUMAN

Vexin

0.302

TM109_HUMAN

Transmembrane protein 109

0.302

MALL_HUMAN

MAL-like protein

0.302

CO062_HUMAN

Uncharacterized protein C15orf62, mitochondrial

0.302

O10D4_HUMAN

Putative olfactory receptor 10D4

0.316

M4A8_HUMAN

Membrane-spanning 4-domains subfamily A member 8

0.316

I36RA_HUMAN

Interleukin-36 receptor antagonist protein

0.316

OR6C2_HUMAN

Olfactory receptor 6C2

0.316

I27RA_HUMAN

Interleukin-27 receptor subunit alpha

0.316

IQCF6_HUMAN

IQ domain-containing protein F6

0.316

OR6Y1_HUMAN

Olfactory receptor 6Y1

0.316

O2AP1_HUMAN

Olfactory receptor 2AP1

0.316

LMTD2_HUMAN

Lamin tail domain-containing protein 2

0.316

OR1E2_HUMAN

Olfactory receptor 1E2

0.316

O13G1_HUMAN

Olfactory receptor 13G1

0.316

IL1RA_HUMAN

Interleukin-1 receptor antagonist protein

0.316

OR1F1_HUMAN

Olfactory receptor 1F1

0.316

VSIG8_HUMAN

V-set and immunoglobulin domain-containing protein 8

0.316

TM247_HUMAN

Transmembrane protein 247

0.316

O6C68_HUMAN

Olfactory receptor 6C68

0.316

SPAT9_HUMAN

Spermatogenesis-associated protein 9

0.316

ACTL9_HUMAN

Actin-like protein 9

0.316

O13A1_HUMAN

Olfactory receptor 13A1

0.316

FNDC8_HUMAN

Fibronectin type III domain-containing protein 8

0.316

IQCF1_HUMAN

IQ domain-containing protein F1

0.316

T4S19_HUMAN

Transmembrane 4 L6 family member 19

0.316

CNPY1_HUMAN

Protein canopy homolog 1

0.316

OR6F1_HUMAN

Olfactory receptor 6F1

0.316

OR1E1_HUMAN

Olfactory receptor 1E1

0.316

NIBL2_HUMAN

Niban-like protein 2

0.316

OR6C3_HUMAN

Olfactory receptor 6C3

0.316

FAIM3_HUMAN

Fas apoptotic inhibitory molecule 3

0.316

O11G2_HUMAN

Olfactory receptor 11G2

0.316

WFDC5_HUMAN

WAP four-disulfide core domain protein 5

0.316

S10A9_HUMAN

Protein S100-A9

0.316

O11H6_HUMAN

Olfactory receptor 11H6

0.316

AKAP3_HUMAN

A-kinase anchor protein 3

0.316

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

TNFL8_HUMAN

Tumor necrosis factor ligand superfamily member 8

0.310

TM139_HUMAN

Transmembrane protein 139

0.312

CD47_HUMAN

Leukocyte surface antigen CD47

0.346

CF132_HUMAN

Uncharacterized protein C6orf132

0.346

ODFP1_HUMAN

Outer dense fiber protein 1

0.349

IL15_HUMAN

Interleukin-15

0.351

OSTP_HUMAN

Osteopontin

0.354

CD5_HUMAN

T-cell surface glycoprotein CD5

0.354

CD019_HUMAN

Uncharacterized protein C4orf19

0.354

ACRBP_HUMAN

Acrosin-binding protein

0.365

I22R1_HUMAN

Interleukin-22 receptor subunit alpha-1

0.365

LIF_HUMAN

Leukemia inhibitory factor

0.365

ZN777_HUMAN

Zinc finger protein 777

0.368

SPERT_HUMAN

Spermatid-associated protein

0.368

VEXIN_HUMAN

Vexin

0.368

CX3C1_HUMAN

CX3C chemokine receptor 1

0.370

MUCEN_HUMAN

Endomucin

0.373

IL1RA_HUMAN

Interleukin-1 receptor antagonist protein

0.375

ZPBP1_HUMAN

Zona pellucida-binding protein 1

0.375

TM109_HUMAN

Transmembrane protein 109

0.375

TACT_HUMAN

T-cell surface protein tactile

0.375

INGR1_HUMAN

Interferon gamma receptor 1

0.378

BPIB4_HUMAN

BPI fold-containing family B member 4

0.380

PIANP_HUMAN

PILR alpha-associated neural protein

0.380

EMP1_HUMAN

Epithelial membrane protein 1

0.380

I13R1_HUMAN

Interleukin-13 receptor subunit alpha-1

0.380

I10R1_HUMAN

Interleukin-10 receptor subunit alpha

0.383

LRC55_HUMAN

Leucine-rich repeat-containing protein 55

0.383

EGLN_HUMAN

Endoglin

0.383

SHSA5_HUMAN

Protein shisa-5

0.386

PDZD9_HUMAN

PDZ domain-containing protein 9

0.386

EPCR_HUMAN

Endothelial protein C receptor

0.386

TM156_HUMAN

Transmembrane protein 156

0.388

CENPA_HUMAN

Histone H3-like centromeric protein A

0.388

CC198_HUMAN

Uncharacterized protein CCDC198

0.388

MTCP1_HUMAN

Protein p13 MTCP-1

0.391

UPK3L_HUMAN

Uroplakin-3b-like protein 1

0.394

ARM12_HUMAN

Armadillo repeat-containing protein 12

0.394

THY1_HUMAN

Thy-1 membrane glycoprotein

0.395

SHPS1_HUMAN

Tyrosine-protein phosphatase non-receptor type substrate 1

0.395

TREM2_HUMAN

Triggering receptor expressed on myeloid cells 2

0.397

RESF1_HUMAN

Retroelement silencing factor 1

0.397

AKND1_HUMAN

Protein AKNAD1

0.397

S10AB_HUMAN

Protein S100-A11

0.397

TAF1D_HUMAN

TATA box-binding protein-associated factor RNA polymerase I subunit D

0.397

SEM4A_HUMAN

Semaphorin-4A

0.397

INLR1_HUMAN

Interferon lambda receptor 1

0.400

ICOS_HUMAN

Inducible T-cell costimulator

0.400

SIAL_HUMAN

Bone sialoprotein 2

0.400

TB182_HUMAN

182 kDa tankyrase-1-binding protein

0.400

PML_HUMAN

Protein PML

0.400

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 68 organisms (of 929)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy