LRC55_HUMAN 2019

Gene Name LRC55

Description Leucine-rich repeat-containing protein 55

Length 298

9606

Sequence

>sp|Q6ZSA7|LRC55_HUMAN Leucine-rich repeat-containing protein 55
MGDTWAQLPWPGPPHPAMLLISLLLAAGLMHSDAGTSCPVLCTCRNQVVDCSSQRLFSVPPDLPMDTRNLSLAHNRITAVPPGYLTCYMELQVLDLHNNSLMELPRGLFLHAKRLAHLDLSYNNFSHVPADMFQEAHGLVHIDLSHNPWLRRVHPQAFQGLMQLRDLDLSYGGLAFLSLEALEGLPGLVTLQIGGNPWVCGCTMEPLLKWLRNRIQRCTADSQLAECRGPPEVEGAPLFSLTEESFKACHLTLTLDDYLFIAFVGFVVSIASVATNFLLGITANCCHRWSKASEEEEI

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

CC185_HUMAN

Coiled-coil domain-containing protein 185

0.289

TM109_HUMAN

Transmembrane protein 109

0.289

IL23R_HUMAN

Interleukin-23 receptor

0.289

CFC1_HUMAN

Cryptic protein

0.378

CFC1B_HUMAN

Cryptic family protein 1B

0.378

GSG1_HUMAN

Germ cell-specific gene 1 protein

0.378

K1755_HUMAN

Uncharacterized protein KIAA1755

0.378

SIAL_HUMAN

Bone sialoprotein 2

0.392

L37A3_HUMAN

Leucine-rich repeat-containing protein 37A3

0.392

L37A2_HUMAN

Leucine-rich repeat-containing protein 37A2

0.392

TMM54_HUMAN

Transmembrane protein 54

0.392

SACA1_HUMAN

Sperm acrosome membrane-associated protein 1

0.392

A0A0G2JMZ2_HUMAN

Uncharacterized protein

0.392

ZSWM9_HUMAN

Uncharacterized protein ZSWIM9

0.392

PDZD9_HUMAN

PDZ domain-containing protein 9

0.392

ZBTB4_HUMAN

Zinc finger and BTB domain-containing protein 4

0.392

L37A1_HUMAN

Leucine-rich repeat-containing protein 37A

0.392

EGLN_HUMAN

Endoglin

0.392

MB214_HUMAN

Protein mab-21-like 4

0.392

IQCJ_HUMAN

IQ domain-containing protein J

0.392

VSIG4_HUMAN

V-set and immunoglobulin domain-containing protein 4

0.392

CALI_HUMAN

Calicin

0.392

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

TM139_HUMAN

Transmembrane protein 139

0.287

I22R1_HUMAN

Interleukin-22 receptor subunit alpha-1

0.306

TAF1D_HUMAN

TATA box-binding protein-associated factor RNA polymerase I subunit D

0.306

SIAL_HUMAN

Bone sialoprotein 2

0.308

INGR1_HUMAN

Interferon gamma receptor 1

0.322

PIANP_HUMAN

PILR alpha-associated neural protein

0.324

CD47_HUMAN

Leukocyte surface antigen CD47

0.324

CF132_HUMAN

Uncharacterized protein C6orf132

0.324

IL23R_HUMAN

Interleukin-23 receptor

0.327

ODFP1_HUMAN

Outer dense fiber protein 1

0.327

TNFL8_HUMAN

Tumor necrosis factor ligand superfamily member 8

0.327

EGLN_HUMAN

Endoglin

0.327

SHPS1_HUMAN

Tyrosine-protein phosphatase non-receptor type substrate 1

0.342

GSG1_HUMAN

Germ cell-specific gene 1 protein

0.342

THY1_HUMAN

Thy-1 membrane glycoprotein

0.342

RESF1_HUMAN

Retroelement silencing factor 1

0.344

LIF_HUMAN

Leukemia inhibitory factor

0.344

ZN777_HUMAN

Zinc finger protein 777

0.346

VEXIN_HUMAN

Vexin

0.346

TB182_HUMAN

182 kDa tankyrase-1-binding protein

0.346

CA094_HUMAN

Uncharacterized protein C1orf94

0.346

SPERT_HUMAN

Spermatid-associated protein

0.346

CE57L_HUMAN

Centrosomal protein CEP57L1

0.354

MFAP3_HUMAN

Microfibril-associated glycoprotein 3

0.356

SUGP2_HUMAN

SURP and G-patch domain-containing protein 2

0.356

INAR1_HUMAN

Interferon alpha/beta receptor 1

0.356

CD34_HUMAN

Hematopoietic progenitor cell antigen CD34

0.358

CLD16_HUMAN

Claudin-16

0.358

I13R1_HUMAN

Interleukin-13 receptor subunit alpha-1

0.360

KCD19_HUMAN

BTB/POZ domain-containing protein KCTD19

0.360

BPIB4_HUMAN

BPI fold-containing family B member 4

0.360

SHSA5_HUMAN

Protein shisa-5

0.365

EPCR_HUMAN

Endothelial protein C receptor

0.365

PDZD9_HUMAN

PDZ domain-containing protein 9

0.365

IL15_HUMAN

Interleukin-15

0.365

CD5_HUMAN

T-cell surface glycoprotein CD5

0.368

SMRP1_HUMAN

Spermatid-specific manchette-related protein 1

0.370

MROH7_HUMAN

Maestro heat-like repeat-containing protein family member 7

0.370

SACA1_HUMAN

Sperm acrosome membrane-associated protein 1

0.370

VTDB_HUMAN

Vitamin D-binding protein

0.371

IL17B_HUMAN

Interleukin-17B

0.371

ARM12_HUMAN

Armadillo repeat-containing protein 12

0.373

SPT16_HUMAN

Spermatogenesis-associated protein 16

0.373

CDHR3_HUMAN

Cadherin-related family member 3

0.376

INGR2_HUMAN

Interferon gamma receptor 2

0.378

ACRBP_HUMAN

Acrosin-binding protein

0.378

S10AB_HUMAN

Protein S100-A11

0.378

TRI14_HUMAN

Tripartite motif-containing protein 14

0.378

TREM2_HUMAN

Triggering receptor expressed on myeloid cells 2

0.378

IL22_HUMAN

Interleukin-22

0.378

BRNP2_HUMAN

BMP/retinoic acid-inducible neural-specific protein 2

0.378

ICOS_HUMAN

Inducible T-cell costimulator

0.380

PML_HUMAN

Protein PML

0.380

INLR1_HUMAN

Interferon lambda receptor 1

0.380

LSME1_HUMAN

Leucine-rich single-pass membrane protein 1

0.383

CL050_HUMAN

Uncharacterized protein C12orf50

0.383

OSTB_HUMAN

Organic solute transporter subunit beta

0.383

UPKL2_HUMAN

Uroplakin-3b-like protein 2

0.383

CNTF_HUMAN

Ciliary neurotrophic factor

0.383

CX3C1_HUMAN

CX3C chemokine receptor 1

0.383

GKN2_HUMAN

Gastrokine-2

0.383

MB214_HUMAN

Protein mab-21-like 4

0.383

ABEC1_HUMAN

C->U-editing enzyme APOBEC-1

0.383

TNF15_HUMAN

Tumor necrosis factor ligand superfamily member 15

0.385

UPK1B_HUMAN

Uroplakin-1b

0.385

IL18_HUMAN

Interleukin-18

0.387

CD40L_HUMAN

CD40 ligand

0.387

CCL17_HUMAN

C-C motif chemokine 17

0.388

ZPBP1_HUMAN

Zona pellucida-binding protein 1

0.388

CP071_HUMAN

Uncharacterized protein C16orf71

0.388

X3CL1_HUMAN

Fractalkine

0.388

LY86_HUMAN

Lymphocyte antigen 86

0.390

K1755_HUMAN

Uncharacterized protein KIAA1755

0.390

CF163_HUMAN

Uncharacterized protein C6orf163

0.390

HXD13_HUMAN

Homeobox protein Hox-D13

0.390

ZN654_HUMAN

Zinc finger protein 654

0.390

BCAS1_HUMAN

Breast carcinoma-amplified sequence 1

0.392

CCD27_HUMAN

Coiled-coil domain-containing protein 27

0.392

CC110_HUMAN

Coiled-coil domain-containing protein 110

0.392

LAPM5_HUMAN

Lysosomal-associated transmembrane protein 5

0.392

TM215_HUMAN

Transmembrane protein 215

0.392

GKN1_HUMAN

Gastrokine-1

0.395

CAMP_HUMAN

Cathelicidin antimicrobial peptide

0.395

TM171_HUMAN

Transmembrane protein 171

0.395

TM52B_HUMAN

Transmembrane protein 52B

0.395

ECSCR_HUMAN

Endothelial cell-specific chemotaxis regulator

0.395

I10R1_HUMAN

Interleukin-10 receptor subunit alpha

0.395

INAR2_HUMAN

Interferon alpha/beta receptor 2

0.395

CD72_HUMAN

B-cell differentiation antigen CD72

0.395

CKLF6_HUMAN

CKLF-like MARVEL transmembrane domain-containing protein 6

0.395

SNTAN_HUMAN

Sentan

0.395

MALL_HUMAN

MAL-like protein

0.395

A1AG1_HUMAN

Alpha-1-acid glycoprotein 1

0.395

MYOZ3_HUMAN

Myozenin-3

0.395

FYB2_HUMAN

FYN-binding protein 2

0.397

PDCD1_HUMAN

Programmed cell death protein 1

0.397

TSN32_HUMAN

Tetraspanin-32

0.397

CCD68_HUMAN

Coiled-coil domain-containing protein 68

0.397

ZPBP2_HUMAN

Zona pellucida-binding protein 2

0.397

COLC2_HUMAN

Colorectal cancer-associated protein 2

0.400

CC198_HUMAN

Uncharacterized protein CCDC198

0.400

CD019_HUMAN

Uncharacterized protein C4orf19

0.400

OSTP_HUMAN

Osteopontin

0.400

DMRTB_HUMAN

Doublesex- and mab-3-related transcription factor B1

0.400

K2C80_HUMAN

Keratin, type II cytoskeletal 80

0.400

TM156_HUMAN

Transmembrane protein 156

0.400

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 12 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy