P2Y13_HUMAN 2019

Gene Name P2Y13

Description P2Y purinoceptor 13

Length 354

9606

Sequence

>sp|Q9BPV8|P2Y13_HUMAN P2Y purinoceptor 13
MTAAIRRQRELSILPKVTLEAMNTTVMQGFNRSERCPRDTRIVQLVFPALYTVVFLTGILLNTLALWVFVHIPSSSTFIIYLKNTLVADLIMTLMLPFKILSDSHLAPWQLRAFVCRFSSVIFYETMYVGIVLLGLIAFDRFLKIIRPLRNIFLKKPVFAKTVSIFIWFFLFFISLPNTILSNKEATPSSVKKCASLKGPLGLKWHQMVNNICQFIFWTVFILMLVFYVVIAKKVYDSYRKSKSKDRKNNKKLEGKVFVVVAVFFVCFAPFHFARVPYTHSQTNNKTDCRLQNQLFIAKETTLFLAATNICMDPLIYIFLCKKFTEKLPCMQGRKTTASSQENHSSQTDNITLG

Domains

Loading...

Help

What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

ZBTB6_HUMAN

Zinc finger and BTB domain-containing protein 6

0.277

FNDC9_HUMAN

Fibronectin type III domain-containing protein 9

0.289

AREG_HUMAN

Amphiregulin

0.378

MSLN_HUMAN

Mesothelin

0.378

ZC21C_HUMAN

Zinc finger C2HC domain-containing protein 1C

0.378

NPY5R_HUMAN

Neuropeptide Y receptor type 5

0.378

TRI14_HUMAN

Tripartite motif-containing protein 14

0.378

VWCE_HUMAN

von Willebrand factor C and EGF domain-containing protein

0.378

CD40L_HUMAN

CD40 ligand

0.378

MFAP3_HUMAN

Microfibril-associated glycoprotein 3

0.378

CLD16_HUMAN

Claudin-16

0.378

PIANP_HUMAN

PILR alpha-associated neural protein

0.378

APOA1_HUMAN

Apolipoprotein A-I

0.392

Z518B_HUMAN

Zinc finger protein 518B

0.392

F174A_HUMAN

Membrane protein FAM174A

0.392

GKN1_HUMAN

Gastrokine-1

0.392

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

CLD16_HUMAN

Claudin-16

0.303

CD40L_HUMAN

CD40 ligand

0.340

MFAP3_HUMAN

Microfibril-associated glycoprotein 3

0.340

INGR1_HUMAN

Interferon gamma receptor 1

0.342

SN_HUMAN

Sialoadhesin

0.342

I13R1_HUMAN

Interleukin-13 receptor subunit alpha-1

0.344

PIANP_HUMAN

PILR alpha-associated neural protein

0.344

LAPM5_HUMAN

Lysosomal-associated transmembrane protein 5

0.344

EMP1_HUMAN

Epithelial membrane protein 1

0.344

GKN1_HUMAN

Gastrokine-1

0.346

CAMP_HUMAN

Cathelicidin antimicrobial peptide

0.346

PDZD9_HUMAN

PDZ domain-containing protein 9

0.349

CCD68_HUMAN

Coiled-coil domain-containing protein 68

0.349

CDHR3_HUMAN

Cadherin-related family member 3

0.360

GSG1_HUMAN

Germ cell-specific gene 1 protein

0.360

THY1_HUMAN

Thy-1 membrane glycoprotein

0.360

TREM2_HUMAN

Triggering receptor expressed on myeloid cells 2

0.363

ACRBP_HUMAN

Acrosin-binding protein

0.363

RESF1_HUMAN

Retroelement silencing factor 1

0.363

TAF1D_HUMAN

TATA box-binding protein-associated factor RNA polymerase I subunit D

0.363

INGR2_HUMAN

Interferon gamma receptor 2

0.363

S10AB_HUMAN

Protein S100-A11

0.363

AKND1_HUMAN

Protein AKNAD1

0.363

ICOS_HUMAN

Inducible T-cell costimulator

0.365

VEXIN_HUMAN

Vexin

0.365

ZN639_HUMAN

Zinc finger protein 639

0.365

IGJ_HUMAN

Immunoglobulin J chain

0.370

AREG_HUMAN

Amphiregulin

0.371

TNF15_HUMAN

Tumor necrosis factor ligand superfamily member 15

0.371

INAR1_HUMAN

Interferon alpha/beta receptor 1

0.373

SUGP2_HUMAN

SURP and G-patch domain-containing protein 2

0.373

IKZF3_HUMAN

Zinc finger protein Aiolos

0.376

CD34_HUMAN

Hematopoietic progenitor cell antigen CD34

0.376

ZN654_HUMAN

Zinc finger protein 654

0.376

CD47_HUMAN

Leukocyte surface antigen CD47

0.378

BPIB4_HUMAN

BPI fold-containing family B member 4

0.378

PPR17_HUMAN

Protein phosphatase 1 regulatory subunit 17

0.378

AMGO2_HUMAN

Amphoterin-induced protein 2

0.378

TMM54_HUMAN

Transmembrane protein 54

0.378

CF132_HUMAN

Uncharacterized protein C6orf132

0.378

TM52B_HUMAN

Transmembrane protein 52B

0.380

TM171_HUMAN

Transmembrane protein 171

0.380

LRAD1_HUMAN

Low-density lipoprotein receptor class A domain-containing protein 1

0.380

SNTAN_HUMAN

Sentan

0.380

SHSA5_HUMAN

Protein shisa-5

0.383

FYB2_HUMAN

FYN-binding protein 2

0.383

ODF2L_HUMAN

Protein BCAP

0.383

ETV3_HUMAN

ETS translocation variant 3

0.385

ZP2_HUMAN

Zona pellucida sperm-binding protein 2

0.385

CD5_HUMAN

T-cell surface glycoprotein CD5

0.386

PSPC_HUMAN

Pulmonary surfactant-associated protein C

0.386

VTDB_HUMAN

Vitamin D-binding protein

0.387

IL5RA_HUMAN

Interleukin-5 receptor subunit alpha

0.387

BCLF1_HUMAN

Bcl-2-associated transcription factor 1

0.387

SACA1_HUMAN

Sperm acrosome membrane-associated protein 1

0.388

SMIM3_HUMAN

Small integral membrane protein 3

0.388

CSF3_HUMAN

Granulocyte colony-stimulating factor

0.392

ROBO4_HUMAN

Roundabout homolog 4

0.392

MMRN1_HUMAN

Multimerin-1

0.395

LIF_HUMAN

Leukemia inhibitory factor

0.395

TRI14_HUMAN

Tripartite motif-containing protein 14

0.395

IL22_HUMAN

Interleukin-22

0.395

PML_HUMAN

Protein PML

0.397

CA094_HUMAN

Uncharacterized protein C1orf94

0.397

SPERT_HUMAN

Spermatid-associated protein

0.397

ZN326_HUMAN

DBIRD complex subunit ZNF326

0.398

CD28_HUMAN

T-cell-specific surface glycoprotein CD28

0.398

LRIF1_HUMAN

Ligand-dependent nuclear receptor-interacting factor 1

0.398

TOX2_HUMAN

TOX high mobility group box family member 2

0.398

PPR1C_HUMAN

Protein phosphatase 1 regulatory subunit 1C

0.398

F13B_HUMAN

Coagulation factor XIII B chain

0.400

CX3C1_HUMAN

CX3C chemokine receptor 1

0.400

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 12 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy