IGJ_HUMAN 2019

Gene Name IGJ

Description Immunoglobulin J chain

Length 159

9606

Sequence

>sp|P01591|IGJ_HUMAN Immunoglobulin J chain
MKNHLLFWGVLAVFIKAVHVKAQEDERIVLVDNKCKCARITSRIIRSSEDPNEDIVERNIRIIVPLNNRENISDPTSPLRTRFVYHLSDLCKKCDPTEVELDNQIVTATQSNICDEDSATETCYTYDRNKCYTAVVPLVYGGETKMVETALTPDACYPD

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

PSYR_HUMAN

Psychosine receptor

0.000

SACA1_HUMAN

Sperm acrosome membrane-associated protein 1

0.289

L37A3_HUMAN

Leucine-rich repeat-containing protein 37A3

0.289

TAAR5_HUMAN

Trace amine-associated receptor 5

0.289

L37A1_HUMAN

Leucine-rich repeat-containing protein 37A

0.289

EGLN_HUMAN

Endoglin

0.289

VSIG4_HUMAN

V-set and immunoglobulin domain-containing protein 4

0.289

MB214_HUMAN

Protein mab-21-like 4

0.289

L37A2_HUMAN

Leucine-rich repeat-containing protein 37A2

0.289

SIAL_HUMAN

Bone sialoprotein 2

0.289

A0A0G2JMZ2_HUMAN

Uncharacterized protein

0.289

IQCJ_HUMAN

IQ domain-containing protein J

0.289

NCMAP_HUMAN

Noncompact myelin-associated protein

0.302

CX3C1_HUMAN

CX3C chemokine receptor 1

0.302

DMRTB_HUMAN

Doublesex- and mab-3-related transcription factor B1

0.302

ICOS_HUMAN

Inducible T-cell costimulator

0.302

IRAK2_HUMAN

Interleukin-1 receptor-associated kinase-like 2

0.392

AKND1_HUMAN

Protein AKNAD1

0.392

AKAP8_HUMAN

A-kinase anchor protein 8

0.392

GIMD1_HUMAN

GTPase IMAP family member GIMD1

0.392

INGR1_HUMAN

Interferon gamma receptor 1

0.392

LPAR5_HUMAN

Lysophosphatidic acid receptor 5

0.392

MFAP5_HUMAN

Microfibrillar-associated protein 5

0.392

ZN654_HUMAN

Zinc finger protein 654

0.392

LRC8B_HUMAN

Volume-regulated anion channel subunit LRRC8B

0.392

IL22_HUMAN

Interleukin-22

0.392

CCD27_HUMAN

Coiled-coil domain-containing protein 27

0.392

ICOSL_HUMAN

ICOS ligand

0.392

IGSF1_HUMAN

Immunoglobulin superfamily member 1

0.392

ZBTB6_HUMAN

Zinc finger and BTB domain-containing protein 6

0.392

TAF1D_HUMAN

TATA box-binding protein-associated factor RNA polymerase I subunit D

0.392

REG4_HUMAN

Regenerating islet-derived protein 4

0.392

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

IGSF1_HUMAN

Immunoglobulin superfamily member 1

0.243

TRI14_HUMAN

Tripartite motif-containing protein 14

0.331

IL22_HUMAN

Interleukin-22

0.331

TREM2_HUMAN

Triggering receptor expressed on myeloid cells 2

0.331

VEXIN_HUMAN

Vexin

0.333

ZN639_HUMAN

Zinc finger protein 639

0.333

ICOS_HUMAN

Inducible T-cell costimulator

0.333

VSIG4_HUMAN

V-set and immunoglobulin domain-containing protein 4

0.338

TRAT1_HUMAN

T-cell receptor-associated transmembrane adapter 1

0.341

CLD16_HUMAN

Claudin-16

0.346

INGR1_HUMAN

Interferon gamma receptor 1

0.346

CD34_HUMAN

Hematopoietic progenitor cell antigen CD34

0.346

PIANP_HUMAN

PILR alpha-associated neural protein

0.349

BCAS1_HUMAN

Breast carcinoma-amplified sequence 1

0.349

LAPM5_HUMAN

Lysosomal-associated transmembrane protein 5

0.349

CF132_HUMAN

Uncharacterized protein C6orf132

0.349

CAMP_HUMAN

Cathelicidin antimicrobial peptide

0.351

GKN1_HUMAN

Gastrokine-1

0.351

SHSA5_HUMAN

Protein shisa-5

0.354

FYB2_HUMAN

FYN-binding protein 2

0.354

EVI2A_HUMAN

Protein EVI2A

0.359

THY1_HUMAN

Thy-1 membrane glycoprotein

0.365

FSHB_HUMAN

Follitropin subunit beta

0.365

GSG1_HUMAN

Germ cell-specific gene 1 protein

0.365

ACRBP_HUMAN

Acrosin-binding protein

0.368

S10AB_HUMAN

Protein S100-A11

0.368

RESF1_HUMAN

Retroelement silencing factor 1

0.368

TAF1D_HUMAN

TATA box-binding protein-associated factor RNA polymerase I subunit D

0.368

ZN777_HUMAN

Zinc finger protein 777

0.370

CA094_HUMAN

Uncharacterized protein C1orf94

0.370

P2Y13_HUMAN

P2Y purinoceptor 13

0.370

SPERT_HUMAN

Spermatid-associated protein

0.370

PML_HUMAN

Protein PML

0.370

CX3C1_HUMAN

CX3C chemokine receptor 1

0.373

GKN2_HUMAN

Gastrokine-2

0.373

MISSL_HUMAN

MAPK-interacting and spindle-stabilizing protein-like

0.375

TRI41_HUMAN

E3 ubiquitin-protein ligase TRIM41

0.378

SUGP2_HUMAN

SURP and G-patch domain-containing protein 2

0.378

NCMAP_HUMAN

Noncompact myelin-associated protein

0.378

MFAP3_HUMAN

Microfibril-associated glycoprotein 3

0.378

INAR1_HUMAN

Interferon alpha/beta receptor 1

0.378

CD40L_HUMAN

CD40 ligand

0.378

FA83A_HUMAN

Protein FAM83A

0.380

ZN654_HUMAN

Zinc finger protein 654

0.380

PPR17_HUMAN

Protein phosphatase 1 regulatory subunit 17

0.383

CD47_HUMAN

Leukocyte surface antigen CD47

0.383

KCD19_HUMAN

BTB/POZ domain-containing protein KCTD19

0.383

BPIB4_HUMAN

BPI fold-containing family B member 4

0.383

TNFL8_HUMAN

Tumor necrosis factor ligand superfamily member 8

0.386

TM52B_HUMAN

Transmembrane protein 52B

0.386

SNTAN_HUMAN

Sentan

0.386

IL23R_HUMAN

Interleukin-23 receptor

0.386

ICOSL_HUMAN

ICOS ligand

0.386

LNP1_HUMAN

Leukemia NUP98 fusion partner 1

0.386

TM171_HUMAN

Transmembrane protein 171

0.386

ODFP1_HUMAN

Outer dense fiber protein 1

0.386

CD72_HUMAN

B-cell differentiation antigen CD72

0.386

CKLF6_HUMAN

CKLF-like MARVEL transmembrane domain-containing protein 6

0.386

I10R1_HUMAN

Interleukin-10 receptor subunit alpha

0.386

EGLN_HUMAN

Endoglin

0.386

MYOZ3_HUMAN

Myozenin-3

0.386

OPT_HUMAN

Opticin

0.388

TPO_HUMAN

Thrombopoietin

0.388

EPCR_HUMAN

Endothelial protein C receptor

0.388

ZPBP2_HUMAN

Zona pellucida-binding protein 2

0.388

ACRO_HUMAN

Acrosin

0.388

IL15_HUMAN

Interleukin-15

0.388

KCD18_HUMAN

BTB/POZ domain-containing protein KCTD18

0.388

ODF2L_HUMAN

Protein BCAP

0.388

TM139_HUMAN

Transmembrane protein 139

0.388

CD5_HUMAN

T-cell surface glycoprotein CD5

0.391

VTDB_HUMAN

Vitamin D-binding protein

0.392

SMIM3_HUMAN

Small integral membrane protein 3

0.394

SHLD1_HUMAN

Shieldin complex subunit 1

0.394

NPY5R_HUMAN

Neuropeptide Y receptor type 5

0.394

PDPN_HUMAN

Podoplanin

0.394

MROH7_HUMAN

Maestro heat-like repeat-containing protein family member 7

0.394

MTCP1_HUMAN

Protein p13 MTCP-1

0.394

SACA1_HUMAN

Sperm acrosome membrane-associated protein 1

0.394

CQ064_HUMAN

Uncharacterized protein C17orf64

0.396

ZN282_HUMAN

Zinc finger protein 282

0.396

CDHR3_HUMAN

Cadherin-related family member 3

0.397

CD8B2_HUMAN

Putative T-cell surface glycoprotein CD8 beta-2 chain

0.400

MMRN1_HUMAN

Multimerin-1

0.400

VSIG1_HUMAN

V-set and immunoglobulin domain-containing protein 1

0.400

INGR2_HUMAN

Interferon gamma receptor 2

0.400

AKAP8_HUMAN

A-kinase anchor protein 8

0.400

MFAP5_HUMAN

Microfibrillar-associated protein 5

0.400

LIF_HUMAN

Leukemia inhibitory factor

0.400

ZC21C_HUMAN

Zinc finger C2HC domain-containing protein 1C

0.400

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 11 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy