WDR41_HUMAN 2019

Gene Name WDR41

Description WD repeat-containing protein 41

Length 459

9606

Sequence

>sp|Q9HAD4|WDR41_HUMAN WD repeat-containing protein 41
MLRWLIGGGREPQGLAEKSPLQTIGEEQTQNPYTELLVLKAHHDIVRFLVQLDDYRFASAGDDGIVVVWNAQTGEKLLELNGHTQKITAIITFPSLESCEEKNQLILTASADRTVIVWDGDTTRQVQRISCFQSTVKCLTVLQRLDVWLSGGNDLCVWNRKLDLLCKTSHLSDTGISALVEIPKNCVVAAVGKELIIFRLVAPTEGSLEWDILEVKRLLDHQDNILSLINVNDLSFVTGSHVGELIIWDALDWTMQAYERNFWDPSPQLDTQQEIKLCQKSNDISIHHFTCDEENVFAAVGRGLYVYSLQMKRVIACQKTAHDSNVLHVARLPNRQLISCSEDGSVRIWELREKQQLAAEPVPTGFFNMWGFGRVSKQASQPVKKQQENATSCSLELIGDLIGHSSSVEMFLYFEDHGLVTCSADHLIILWKNGERESGLRSLRLFQKLEENGDLYLAV

Domains

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Help

What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

FBX4_HUMAN

F-box only protein 4

0.359

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

NJMU_HUMAN

Protein Njmu-R1

0.319

DEND3_HUMAN

DENN domain-containing protein 3

0.324

KNDC1_HUMAN

Kinase non-catalytic C-lobe domain-containing protein 1

0.326

FBX4_HUMAN

F-box only protein 4

0.335

CCNF_HUMAN

Cyclin-F

0.336

SPICE_HUMAN

Spindle and centriole-associated protein 1

0.338

STRA6_HUMAN

Receptor for retinol uptake STRA6

0.346

CEP85_HUMAN

Centrosomal protein of 85 kDa

0.349

HUNK_HUMAN

Hormonally up-regulated neu tumor-associated kinase

0.349

MID51_HUMAN

Mitochondrial dynamics protein MID51

0.354

AGRV1_HUMAN

Adhesion G-protein coupled receptor V1

0.354

DIXC1_HUMAN

Dixin

0.354

AFAP1_HUMAN

Actin filament-associated protein 1

0.354

STXB4_HUMAN

Syntaxin-binding protein 4

0.360

F167A_HUMAN

Protein FAM167A

0.361

LRC42_HUMAN

Leucine-rich repeat-containing protein 42

0.361

MTBP_HUMAN

Mdm2-binding protein

0.361

PARI_HUMAN

PCNA-interacting partner

0.361

WDCP_HUMAN

WD repeat and coiled-coil-containing protein

0.363

SNP47_HUMAN

Synaptosomal-associated protein 47

0.363

ZFY27_HUMAN

Protrudin

0.363

COMD1_HUMAN

COMM domain-containing protein 1

0.364

FANCB_HUMAN

Fanconi anemia group B protein

0.366

NTF3_HUMAN

Neurotrophin-3

0.368

IQCB1_HUMAN

IQ calmodulin-binding motif-containing protein 1

0.368

IRF2_HUMAN

Interferon regulatory factor 2

0.370

IKBP1_HUMAN

Interleukin-1 receptor-associated kinase 1-binding protein 1

0.370

MIEAP_HUMAN

Mitochondria-eating protein

0.370

HECD4_HUMAN

Probable E3 ubiquitin-protein ligase HECTD4

0.370

IRF1_HUMAN

Interferon regulatory factor 1

0.370

GP161_HUMAN

G-protein coupled receptor 161

0.371

CE034_HUMAN

Uncharacterized protein C5orf34

0.371

NKAP1_HUMAN

Uncharacterized protein NKAPD1

0.373

NECA1_HUMAN

N-terminal EF-hand calcium-binding protein 1

0.373

USPL1_HUMAN

SUMO-specific isopeptidase USPL1

0.373

CEP63_HUMAN

Centrosomal protein of 63 kDa

0.373

AMPO_HUMAN

Aminopeptidase O

0.375

CNTLN_HUMAN

Centlein

0.375

F199X_HUMAN

Protein FAM199X

0.376

LBN_HUMAN

Limbin

0.376

ZFAT_HUMAN

Zinc finger protein ZFAT

0.376

COMD6_HUMAN

COMM domain-containing protein 6

0.376

USH2A_HUMAN

Usherin

0.376

CE112_HUMAN

Centrosomal protein of 112 kDa

0.376

SLF2_HUMAN

SMC5-SMC6 complex localization factor protein 2

0.378

AF1L2_HUMAN

Actin filament-associated protein 1-like 2

0.378

M1AP_HUMAN

Meiosis 1 arrest protein

0.378

MPP9_HUMAN

M-phase phosphoprotein 9

0.378

AF1L1_HUMAN

Actin filament-associated protein 1-like 1

0.378

CEP57_HUMAN

Centrosomal protein of 57 kDa

0.383

RGS22_HUMAN

Regulator of G-protein signaling 22

0.383

TXD16_HUMAN

Thioredoxin domain-containing protein 16

0.383

TICRR_HUMAN

Treslin

0.383

TM168_HUMAN

Transmembrane protein 168

0.383

NCOA4_HUMAN

Nuclear receptor coactivator 4

0.384

FBX41_HUMAN

F-box only protein 41

0.384

MOONR_HUMAN

Protein moonraker

0.386

PCD20_HUMAN

Protocadherin-20

0.386

SPIDR_HUMAN

DNA repair-scaffolding protein

0.386

CCD18_HUMAN

Coiled-coil domain-containing protein 18

0.386

SFRP3_HUMAN

Secreted frizzled-related protein 3

0.388

PRDM4_HUMAN

PR domain zinc finger protein 4

0.388

CP20A_HUMAN

Cytochrome P450 20A1

0.389

MTFR1_HUMAN

Mitochondrial fission regulator 1

0.390

GP173_HUMAN

Probable G-protein coupled receptor 173

0.390

CH076_HUMAN

Uncharacterized protein C8orf76

0.390

DERM_HUMAN

Dermatopontin

0.390

TNF10_HUMAN

Tumor necrosis factor ligand superfamily member 10

0.390

ICE1_HUMAN

Little elongation complex subunit 1

0.390

SLAI2_HUMAN

SLAIN motif-containing protein 2

0.390

GPR63_HUMAN

Probable G-protein coupled receptor 63

0.390

ZN451_HUMAN

E3 SUMO-protein ligase ZNF451

0.390

FBXL5_HUMAN

F-box/LRR-repeat protein 5

0.391

ADPRH_HUMAN

[Protein ADP-ribosylarginine] hydrolase

0.391

AIF1L_HUMAN

Allograft inflammatory factor 1-like

0.391

PRDM2_HUMAN

PR domain zinc finger protein 2

0.391

TARSH_HUMAN

Target of Nesh-SH3

0.391

TSN3_HUMAN

Tetraspanin-3

0.392

CEP70_HUMAN

Centrosomal protein of 70 kDa

0.392

OIT3_HUMAN

Oncoprotein-induced transcript 3 protein

0.392

RD3_HUMAN

Protein RD3

0.394

BST1_HUMAN

ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2

0.394

GNPTG_HUMAN

N-acetylglucosamine-1-phosphotransferase subunit gamma

0.395

CH034_HUMAN

Uncharacterized protein C8orf34

0.396

NUSAP_HUMAN

Nucleolar and spindle-associated protein 1

0.396

DBLOH_HUMAN

Diablo homolog, mitochondrial

0.397

NSMF_HUMAN

NMDA receptor synaptonuclear signaling and neuronal migration factor

0.397

K0355_HUMAN

Uncharacterized protein KIAA0355

0.397

CSPG2_HUMAN

Versican core protein

0.397

TNIP1_HUMAN

TNFAIP3-interacting protein 1

0.397

CYBC1_HUMAN

Cytochrome b-245 chaperone 1

0.397

BCL10_HUMAN

B-cell lymphoma/leukemia 10

0.399

SLAI1_HUMAN

SLAIN motif-containing protein 1

0.399

SNX10_HUMAN

Sorting nexin-10

0.399

GSDME_HUMAN

Gasdermin-E

0.399

NAGPA_HUMAN

N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase

0.400

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 28 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy