NIF3L_HUMAN 2019

Gene Name NIF3L

Description NIF3-like protein 1

Length 377

9606

Sequence

>sp|Q9GZT8|NIF3L_HUMAN NIF3-like protein 1
MLSSCVRPVPTTVRFVDSLICNSSRSFMDLKALLSSLNDFASLSFAESWDNVGLLVEPSPPHTVNTLFLTNDLTEEVMEEVLQKKADLILSYHPPIFRPMKRITWNTWKERLVIRALENRVGIYSPHTAYDAAPQGVNNWLAKGLGACTSRPIHPSKAPNYPTEGNHRVEFNVNYTQDLDKVMSAVKGIDGVSVTSFSARTGNEEQTRINLNCTQKALMQVVDFLSRNKQLYQKTEILSLEKPLLLHTGMGRLCTLDESVSLATMIDRIKRHLKLSHIRLALGVGRTLESQVKVVALCAGSGSSVLQGVEADLYLTGEMSHHDTLDAASQGINVILCEHSNTERGFLSDLRDMLDSHLENKINIILSETDRDPLQVV

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

No protein with similar profile across the domains were found

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

POMT2_HUMAN

Protein O-mannosyl-transferase 2

0.282

SYNC_HUMAN

Asparagine--tRNA ligase, cytoplasmic

0.306

SYRM_HUMAN

Probable arginine--tRNA ligase, mitochondrial

0.315

TOM70_HUMAN

Mitochondrial import receptor subunit TOM70

0.330

PAK2_HUMAN

Serine/threonine-protein kinase PAK 2

0.337

SEPT7_HUMAN

Septin-7

0.341

GATA4_HUMAN

Transcription factor GATA-4

0.343

CLCN3_HUMAN

H(+)/Cl(-) exchange transporter 3

0.343

IQGA1_HUMAN

Ras GTPase-activating-like protein IQGAP1

0.344

ATP9A_HUMAN

Probable phospholipid-transporting ATPase IIA

0.344

SRF_HUMAN

Serum response factor

0.346

SLMAP_HUMAN

Sarcolemmal membrane-associated protein

0.346

CUL1_HUMAN

Cullin-1

0.347

PAK1_HUMAN

Serine/threonine-protein kinase PAK 1

0.347

PAK3_HUMAN

Serine/threonine-protein kinase PAK 3

0.347

GOLP3_HUMAN

Golgi phosphoprotein 3

0.349

ERGI2_HUMAN

Endoplasmic reticulum-Golgi intermediate compartment protein 2

0.349

FBXW7_HUMAN

F-box/WD repeat-containing protein 7

0.350

CLCN5_HUMAN

H(+)/Cl(-) exchange transporter 5

0.350

HEM1_HUMAN

5-aminolevulinate synthase, nonspecific, mitochondrial

0.350

H33_HUMAN

Histone H3.3

0.350

CLCN4_HUMAN

H(+)/Cl(-) exchange transporter 4

0.350

GATA6_HUMAN

Transcription factor GATA-6

0.350

AL4A1_HUMAN

Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial

0.350

BAT1_HUMAN

b(0,+)-type amino acid transporter 1

0.353

VIGLN_HUMAN

Vigilin

0.354

GATA5_HUMAN

Transcription factor GATA-5

0.356

DOP1_HUMAN

Protein dopey-1

0.358

RHOA_HUMAN

Transforming protein RhoA

0.359

GGPPS_HUMAN

Geranylgeranyl pyrophosphate synthase

0.359

SOS1_HUMAN

Son of sevenless homolog 1

0.360

RAGP1_HUMAN

Ran GTPase-activating protein 1

0.361

UB2G2_HUMAN

Ubiquitin-conjugating enzyme E2 G2

0.362

ATP9B_HUMAN

Probable phospholipid-transporting ATPase IIB

0.362

PP2BA_HUMAN

Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform

0.363

GSH1_HUMAN

Glutamate--cysteine ligase catalytic subunit

0.363

SURF4_HUMAN

Surfeit locus protein 4

0.363

NPRL2_HUMAN

GATOR complex protein NPRL2

0.365

SUPT3_HUMAN

Transcription initiation protein SPT3 homolog

0.366

DEPD5_HUMAN

GATOR complex protein DEPDC5

0.366

ZNT1_HUMAN

Zinc transporter 1

0.367

HIP1_HUMAN

Huntingtin-interacting protein 1

0.370

DPP4_HUMAN

Dipeptidyl peptidase 4

0.370

DPOG1_HUMAN

DNA polymerase subunit gamma-1

0.371

RICTR_HUMAN

Rapamycin-insensitive companion of mTOR

0.371

HIP1R_HUMAN

Huntingtin-interacting protein 1-related protein

0.372

DPP10_HUMAN

Inactive dipeptidyl peptidase 10

0.372

GATA3_HUMAN

Trans-acting T-cell-specific transcription factor GATA-3

0.373

KAP2_HUMAN

cAMP-dependent protein kinase type II-alpha regulatory subunit

0.373

WDR59_HUMAN

GATOR complex protein WDR59

0.374

COX5A_HUMAN

Cytochrome c oxidase subunit 5A, mitochondrial

0.374

DOP2_HUMAN

Protein dopey-2

0.375

RRAGA_HUMAN

Ras-related GTP-binding protein A

0.375

TM9S2_HUMAN

Transmembrane 9 superfamily member 2

0.375

PGPS1_HUMAN

CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial

0.375

KAP3_HUMAN

cAMP-dependent protein kinase type II-beta regulatory subunit

0.377

GYS2_HUMAN

Glycogen [starch] synthase, liver

0.377

SIR2_HUMAN

NAD-dependent protein deacetylase sirtuin-2

0.377

GDE_HUMAN

Glycogen debranching enzyme

0.378

PAN3_HUMAN

PAN2-PAN3 deadenylation complex subunit PAN3

0.378

GYS1_HUMAN

Glycogen [starch] synthase, muscle

0.379

LIS1_HUMAN

Platelet-activating factor acetylhydrolase IB subunit alpha

0.380

RRAGC_HUMAN

Ras-related GTP-binding protein C

0.380

SEPR_HUMAN

Prolyl endopeptidase FAP

0.380

SOS2_HUMAN

Son of sevenless homolog 2

0.381

PBDC1_HUMAN

Protein PBDC1

0.382

AADAT_HUMAN

Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial

0.382

RHOC_HUMAN

Rho-related GTP-binding protein RhoC

0.382

IQGA3_HUMAN

Ras GTPase-activating-like protein IQGAP3

0.383

CMC1_HUMAN

Calcium-binding mitochondrial carrier protein Aralar1

0.383

GATA2_HUMAN

Endothelial transcription factor GATA-2

0.383

AVL9_HUMAN

Late secretory pathway protein AVL9 homolog

0.384

ACON_HUMAN

Aconitate hydratase, mitochondrial

0.384

RMND1_HUMAN

Required for meiotic nuclear division protein 1 homolog

0.384

PP2BC_HUMAN

Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform

0.384

S2536_HUMAN

Solute carrier family 25 member 36

0.385

CACP_HUMAN

Carnitine O-acetyltransferase

0.385

DYR_HUMAN

Dihydrofolate reductase

0.385

DOT1L_HUMAN

Histone-lysine N-methyltransferase, H3 lysine-79 specific

0.386

RCC1_HUMAN

Regulator of chromosome condensation

0.387

PP2BB_HUMAN

Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform

0.388

SYYC_HUMAN

Tyrosine--tRNA ligase, cytoplasmic

0.389

S2533_HUMAN

Solute carrier family 25 member 33

0.389

RAD52_HUMAN

DNA repair protein RAD52 homolog

0.389

QPCT_HUMAN

Glutaminyl-peptide cyclotransferase

0.389

OGFD1_HUMAN

Prolyl 3-hydroxylase OGFOD1

0.390

SNX12_HUMAN

Sorting nexin-12

0.391

AT2C1_HUMAN

Calcium-transporting ATPase type 2C member 1

0.392

SNX3_HUMAN

Sorting nexin-3

0.392

DPP6_HUMAN

Dipeptidyl aminopeptidase-like protein 6

0.393

SORL_HUMAN

Sortilin-related receptor

0.393

HEM0_HUMAN

5-aminolevulinate synthase, erythroid-specific, mitochondrial

0.393

TRM44_HUMAN

Probable tRNA (uracil-O(2)-)-methyltransferase

0.393

STRP1_HUMAN

Striatin-interacting protein 1

0.393

AT133_HUMAN

Probable cation-transporting ATPase 13A3

0.393

TSC2_HUMAN

Tuberin

0.393

ARGI2_HUMAN

Arginase-2, mitochondrial

0.394

DYHC1_HUMAN

Cytoplasmic dynein 1 heavy chain 1

0.394

DHR11_HUMAN

Dehydrogenase/reductase SDR family member 11

0.395

GORS2_HUMAN

Golgi reassembly-stacking protein 2

0.395

RRAGD_HUMAN

Ras-related GTP-binding protein D

0.396

PAN2_HUMAN

PAN2-PAN3 deadenylation complex catalytic subunit PAN2

0.396

PLPL6_HUMAN

Neuropathy target esterase

0.397

SYCC_HUMAN

Cysteine--tRNA ligase, cytoplasmic

0.397

COR1C_HUMAN

Coronin-1C

0.397

LIPT_HUMAN

Lipoyltransferase 1, mitochondrial

0.397

S38AB_HUMAN

Putative sodium-coupled neutral amino acid transporter 11

0.398

PPBT_HUMAN

Alkaline phosphatase, tissue-nonspecific isozyme

0.399

DOCK5_HUMAN

Dedicator of cytokinesis protein 5

0.399

S39A9_HUMAN

Zinc transporter ZIP9

0.400

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 101 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy