ACO13_HUMAN 2019

Gene Name ACO13

Description Acyl-coenzyme A thioesterase 13

Length 140

9606

Sequence

>sp|Q9NPJ3|ACO13_HUMAN Acyl-coenzyme A thioesterase 13
MTSMTQSLREVIKAMTKARNFERVLGKITLVSAAPGKVICEMKVEEEHTNAIGTLHGGLTATLVDNISTMALLCTERGAPGVSVDMNITYMSPAKLGEDIVITAHVLKQGKTLAFTSVDLTNKATGKLIAQGRHTKHLGN

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

No protein with similar profile across the domains were found

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

ACSF2_HUMAN

Acyl-CoA synthetase family member 2, mitochondrial

0.318

CSN1_HUMAN

COP9 signalosome complex subunit 1

0.323

ACLY_HUMAN

ATP-citrate synthase

0.326

PPIL2_HUMAN

RING-type E3 ubiquitin-protein ligase PPIL2

0.332

CSN4_HUMAN

COP9 signalosome complex subunit 4

0.332

GCDH_HUMAN

Glutaryl-CoA dehydrogenase, mitochondrial

0.345

RIC1_HUMAN

RAB6A-GEF complex partner protein 1

0.346

CCD12_HUMAN

Coiled-coil domain-containing protein 12

0.346

HEXB_HUMAN

Beta-hexosaminidase subunit beta

0.351

PPWD1_HUMAN

Peptidylprolyl isomerase domain and WD repeat-containing protein 1

0.352

GPTC1_HUMAN

G patch domain-containing protein 1

0.352

CHRD1_HUMAN

Cysteine and histidine-rich domain-containing protein 1

0.353

CSN7A_HUMAN

COP9 signalosome complex subunit 7a

0.353

RBM39_HUMAN

RNA-binding protein 39

0.353

CSN7B_HUMAN

COP9 signalosome complex subunit 7b

0.355

EIF3E_HUMAN

Eukaryotic translation initiation factor 3 subunit E

0.358

MCCB_HUMAN

Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

0.359

EIF3M_HUMAN

Eukaryotic translation initiation factor 3 subunit M

0.359

IVD_HUMAN

Isovaleryl-CoA dehydrogenase, mitochondrial

0.360

CAND1_HUMAN

Cullin-associated NEDD8-dissociated protein 1

0.360

EXOC1_HUMAN

Exocyst complex component 1

0.361

KDM8_HUMAN

Bifunctional peptidase and arginyl-hydroxylase JMJD5

0.361

PIMT_HUMAN

Protein-L-isoaspartate(D-aspartate) O-methyltransferase

0.362

ODBA_HUMAN

2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial

0.362

PPT1_HUMAN

Palmitoyl-protein thioesterase 1

0.362

PCP_HUMAN

Lysosomal Pro-X carboxypeptidase

0.364

EIF3L_HUMAN

Eukaryotic translation initiation factor 3 subunit L

0.366

UVRAG_HUMAN

UV radiation resistance-associated gene protein

0.367

ODBB_HUMAN

2-oxoisovalerate dehydrogenase subunit beta, mitochondrial

0.367

LACB2_HUMAN

Endoribonuclease LACTB2

0.368

GALM_HUMAN

Aldose 1-epimerase

0.368

PPIL1_HUMAN

Peptidyl-prolyl cis-trans isomerase-like 1

0.368

RBM25_HUMAN

RNA-binding protein 25

0.368

EIF3D_HUMAN

Eukaryotic translation initiation factor 3 subunit D

0.368

TFP11_HUMAN

Tuftelin-interacting protein 11

0.369

GALE_HUMAN

UDP-glucose 4-epimerase

0.369

NDUS8_HUMAN

NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial

0.369

WDR48_HUMAN

WD repeat-containing protein 48

0.369

C19L2_HUMAN

CWF19-like protein 2

0.369

ARL8B_HUMAN

ADP-ribosylation factor-like protein 8B

0.369

SYF2_HUMAN

Pre-mRNA-splicing factor SYF2

0.370

CHDH_HUMAN

Choline dehydrogenase, mitochondrial

0.370

NDUV2_HUMAN

NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

0.371

SC16A_HUMAN

Protein transport protein Sec16A

0.373

HEXA_HUMAN

Beta-hexosaminidase subunit alpha

0.373

CP2U1_HUMAN

Cytochrome P450 2U1

0.373

RGP1_HUMAN

RAB6A-GEF complex partner protein 2

0.373

CLPT1_HUMAN

Cleft lip and palate transmembrane protein 1

0.373

CTBL1_HUMAN

Beta-catenin-like protein 1

0.374

DNJC3_HUMAN

DnaJ homolog subfamily C member 3

0.374

AT2A2_HUMAN

Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

0.374

GSTO1_HUMAN

Glutathione S-transferase omega-1

0.374

CP4V2_HUMAN

Cytochrome P450 4V2

0.375

NDUS1_HUMAN

NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial

0.375

NUDC_HUMAN

Nuclear migration protein nudC

0.375

NDUF5_HUMAN

Arginine-hydroxylase NDUFAF5, mitochondrial

0.375

VTA1_HUMAN

Vacuolar protein sorting-associated protein VTA1 homolog

0.377

MOCS1_HUMAN

Molybdenum cofactor biosynthesis protein 1

0.377

CATIN_HUMAN

Cactin

0.377

SCPDL_HUMAN

Saccharopine dehydrogenase-like oxidoreductase

0.378

RBM8A_HUMAN

RNA-binding protein 8A

0.378

U5S1_HUMAN

116 kDa U5 small nuclear ribonucleoprotein component

0.378

COPE_HUMAN

Coatomer subunit epsilon

0.378

GEPH_HUMAN

Gephyrin

0.379

AP2M1_HUMAN

AP-2 complex subunit mu

0.379

EIF3F_HUMAN

Eukaryotic translation initiation factor 3 subunit F

0.379

NDUV1_HUMAN

NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

0.380

MET16_HUMAN

RNA N6-adenosine-methyltransferase METTL16

0.380

MMSA_HUMAN

Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial

0.380

CSN3_HUMAN

COP9 signalosome complex subunit 3

0.380

CSN2_HUMAN

COP9 signalosome complex subunit 2

0.380

CD11B_HUMAN

Cyclin-dependent kinase 11B

0.380

EIF3K_HUMAN

Eukaryotic translation initiation factor 3 subunit K

0.380

TPC10_HUMAN

Trafficking protein particle complex subunit 10

0.381

NDUS2_HUMAN

NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial

0.382

EMC2_HUMAN

ER membrane protein complex subunit 2

0.382

FAN1_HUMAN

Fanconi-associated nuclease 1

0.382

SNR40_HUMAN

U5 small nuclear ribonucleoprotein 40 kDa protein

0.383

CC130_HUMAN

Coiled-coil domain-containing protein 130

0.383

NDUA9_HUMAN

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial

0.383

CPSF5_HUMAN

Cleavage and polyadenylation specificity factor subunit 5

0.384

NDUS4_HUMAN

NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial

0.385

NIPBL_HUMAN

Nipped-B-like protein

0.385

THOC1_HUMAN

THO complex subunit 1

0.385

GALK2_HUMAN

N-acetylgalactosamine kinase

0.386

GID8_HUMAN

Glucose-induced degradation protein 8 homolog

0.386

SND1_HUMAN

Staphylococcal nuclease domain-containing protein 1

0.388

MAK_HUMAN

Serine/threonine-protein kinase MAK

0.389

HCDH_HUMAN

Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial

0.389

RANB9_HUMAN

Ran-binding protein 9

0.389

SC24C_HUMAN

Protein transport protein Sec24C

0.390

RAD1_HUMAN

Cell cycle checkpoint protein RAD1

0.390

DDB1_HUMAN

DNA damage-binding protein 1

0.390

SMYD1_HUMAN

Histone-lysine N-methyltransferase SMYD1

0.391

CP2J2_HUMAN

Cytochrome P450 2J2

0.391

CPSF2_HUMAN

Cleavage and polyadenylation specificity factor subunit 2

0.391

NSRP1_HUMAN

Nuclear speckle splicing regulatory protein 1

0.392

NDUS3_HUMAN

NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

0.392

XRCC6_HUMAN

X-ray repair cross-complementing protein 6

0.392

CD11A_HUMAN

Cyclin-dependent kinase 11A

0.393

BECN1_HUMAN

Beclin-1

0.393

OTUB1_HUMAN

Ubiquitin thioesterase OTUB1

0.393

3HIDH_HUMAN

3-hydroxyisobutyrate dehydrogenase, mitochondrial

0.393

HTR5B_HUMAN

HEAT repeat-containing protein 5B

0.393

EIF3H_HUMAN

Eukaryotic translation initiation factor 3 subunit H

0.394

DNJC8_HUMAN

DnaJ homolog subfamily C member 8

0.394

ESS2_HUMAN

Splicing factor ESS-2 homolog

0.395

VPS54_HUMAN

Vacuolar protein sorting-associated protein 54

0.396

TSSP_HUMAN

Thymus-specific serine protease

0.396

DCA11_HUMAN

DDB1- and CUL4-associated factor 11

0.396

TSN_HUMAN

Translin

0.396

SGPL1_HUMAN

Sphingosine-1-phosphate lyase 1

0.396

EXOC8_HUMAN

Exocyst complex component 8

0.396

MOCOS_HUMAN

Molybdenum cofactor sulfurase

0.396

VPS36_HUMAN

Vacuolar protein-sorting-associated protein 36

0.396

OGT1_HUMAN

UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

0.397

CBSL_HUMAN

Cystathionine beta-synthase-like protein

0.397

CBS_HUMAN

Cystathionine beta-synthase

0.397

STRAP_HUMAN

Serine-threonine kinase receptor-associated protein

0.397

APT_HUMAN

Adenine phosphoribosyltransferase

0.397

KAT3_HUMAN

Kynurenine--oxoglutarate transaminase 3

0.397

CUL3_HUMAN

Cullin-3

0.397

LICH_HUMAN

Lysosomal acid lipase/cholesteryl ester hydrolase

0.397

EXOC5_HUMAN

Exocyst complex component 5

0.397

DHB4_HUMAN

Peroxisomal multifunctional enzyme type 2

0.397

NDUS7_HUMAN

NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

0.397

NDUF6_HUMAN

NADH dehydrogenase (ubiquinone) complex I, assembly factor 6

0.397

PA2G4_HUMAN

Proliferation-associated protein 2G4

0.398

DPYD_HUMAN

Dihydropyrimidine dehydrogenase [NADP(+)]

0.398

NDUF7_HUMAN

Protein arginine methyltransferase NDUFAF7, mitochondrial

0.398

AT2A1_HUMAN

Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

0.398

WDR20_HUMAN

WD repeat-containing protein 20

0.399

AGO3_HUMAN

Protein argonaute-3

0.399

AGO4_HUMAN

Protein argonaute-4

0.399

GLGB_HUMAN

1,4-alpha-glucan-branching enzyme

0.399

SERC_HUMAN

Phosphoserine aminotransferase

0.399

CP2A6_HUMAN

Cytochrome P450 2A6

0.399

VPS51_HUMAN

Vacuolar protein sorting-associated protein 51 homolog

0.399

S45A2_HUMAN

Membrane-associated transporter protein

0.399

DDC_HUMAN

Aromatic-L-amino-acid decarboxylase

0.400

MFAP1_HUMAN

Microfibrillar-associated protein 1

0.400

MDHM_HUMAN

Malate dehydrogenase, mitochondrial

0.400

CGL_HUMAN

Cystathionine gamma-lyase

0.400

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 112 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy