ARMT1_HUMAN 2019

Gene Name ARMT1

Description Protein-glutamate O-methyltransferase

Length 441

9606

Sequence

>sp|Q9H993|ARMT1_HUMAN Protein-glutamate O-methyltransferase
MAVVPASLSGQDVGSFAYLTIKDRIPQILTKVIDTLHRHKSEFFEKHGEEGVEAEKKAISLLSKLRNELQTDKPFIPLVEKFVDTDIWNQYLEYQQSLLNESDGKSRWFYSPWLLVECYMYRRIHEAIIQSPPIDYFDVFKESKEQNFYGSQESIIALCTHLQQLIRTIEDLDENQLKDEFFKLLQISLWGNKCDLSLSGGESSSQNTNVLNSLEDLKPFILLNDMEHLWSLLSNCKKTREKASATRVYIVLDNSGFELVTDLILADFLLSSELATEVHFYGKTIPWFVSDTTIHDFNWLIEQVKHSNHKWMSKCGADWEEYIKMGKWVYHNHIFWTLPHEYCAMPQVAPDLYAELQKAHLILFKGDLNYRKLTGDRKWEFSVPFHQALNGFHPAPLCTIRTLKAEIQVGLQPGQGEQLLASEPSWWTTGKYGIFQYDGPL

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

No protein with similar profile across the domains were found

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

ACON_HUMAN

Aconitate hydratase, mitochondrial

0.292

GSH1_HUMAN

Glutamate--cysteine ligase catalytic subunit

0.301

ACATN_HUMAN

Acetyl-coenzyme A transporter 1

0.302

DEPD5_HUMAN

GATOR complex protein DEPDC5

0.304

AT2C1_HUMAN

Calcium-transporting ATPase type 2C member 1

0.309

VIGLN_HUMAN

Vigilin

0.311

CCHL_HUMAN

Cytochrome c-type heme lyase

0.314

RRAGA_HUMAN

Ras-related GTP-binding protein A

0.315

SOS1_HUMAN

Son of sevenless homolog 1

0.319

S2536_HUMAN

Solute carrier family 25 member 36

0.322

DOT1L_HUMAN

Histone-lysine N-methyltransferase, H3 lysine-79 specific

0.323

NPRL2_HUMAN

GATOR complex protein NPRL2

0.324

COR1C_HUMAN

Coronin-1C

0.324

RRAGC_HUMAN

Ras-related GTP-binding protein C

0.328

DYHC1_HUMAN

Cytoplasmic dynein 1 heavy chain 1

0.328

RCC1_HUMAN

Regulator of chromosome condensation

0.331

RRAGD_HUMAN

Ras-related GTP-binding protein D

0.332

PAN3_HUMAN

PAN2-PAN3 deadenylation complex subunit PAN3

0.333

ARGI2_HUMAN

Arginase-2, mitochondrial

0.333

PAK2_HUMAN

Serine/threonine-protein kinase PAK 2

0.333

S2533_HUMAN

Solute carrier family 25 member 33

0.334

RICTR_HUMAN

Rapamycin-insensitive companion of mTOR

0.335

CLCN3_HUMAN

H(+)/Cl(-) exchange transporter 3

0.336

CACP_HUMAN

Carnitine O-acetyltransferase

0.336

SYCC_HUMAN

Cysteine--tRNA ligase, cytoplasmic

0.336

SYYC_HUMAN

Tyrosine--tRNA ligase, cytoplasmic

0.336

CNDP2_HUMAN

Cytosolic non-specific dipeptidase

0.338

RMND1_HUMAN

Required for meiotic nuclear division protein 1 homolog

0.340

PP2BA_HUMAN

Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform

0.340

CUL1_HUMAN

Cullin-1

0.340

PAK1_HUMAN

Serine/threonine-protein kinase PAK 1

0.340

TOM70_HUMAN

Mitochondrial import receptor subunit TOM70

0.340

PGPS1_HUMAN

CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial

0.340

PAK3_HUMAN

Serine/threonine-protein kinase PAK 3

0.340

AT133_HUMAN

Probable cation-transporting ATPase 13A3

0.341

SOS2_HUMAN

Son of sevenless homolog 2

0.342

STRP1_HUMAN

Striatin-interacting protein 1

0.342

CLCN5_HUMAN

H(+)/Cl(-) exchange transporter 5

0.343

TM9S2_HUMAN

Transmembrane 9 superfamily member 2

0.343

CLCN4_HUMAN

H(+)/Cl(-) exchange transporter 4

0.343

PLPL6_HUMAN

Neuropathy target esterase

0.343

DPP4_HUMAN

Dipeptidyl peptidase 4

0.346

DPP10_HUMAN

Inactive dipeptidyl peptidase 10

0.348

GOLP3_HUMAN

Golgi phosphoprotein 3

0.349

PYC_HUMAN

Pyruvate carboxylase, mitochondrial

0.349

SURF4_HUMAN

Surfeit locus protein 4

0.349

H33_HUMAN

Histone H3.3

0.350

CORO6_HUMAN

Coronin-6

0.350

TBC20_HUMAN

TBC1 domain family member 20

0.350

AL4A1_HUMAN

Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial

0.350

PLPL7_HUMAN

Patatin-like phospholipase domain-containing protein 7

0.350

RRAGB_HUMAN

Ras-related GTP-binding protein B

0.350

LIS1_HUMAN

Platelet-activating factor acetylhydrolase IB subunit alpha

0.351

SEPR_HUMAN

Prolyl endopeptidase FAP

0.351

SLMAP_HUMAN

Sarcolemmal membrane-associated protein

0.353

CC14A_HUMAN

Dual specificity protein phosphatase CDC14A

0.354

SEPT7_HUMAN

Septin-7

0.354

PAN2_HUMAN

PAN2-PAN3 deadenylation complex catalytic subunit PAN2

0.354

CMC1_HUMAN

Calcium-binding mitochondrial carrier protein Aralar1

0.354

GGPPS_HUMAN

Geranylgeranyl pyrophosphate synthase

0.356

S39A9_HUMAN

Zinc transporter ZIP9

0.356

HID1_HUMAN

Protein HID1

0.356

DC1I2_HUMAN

Cytoplasmic dynein 1 intermediate chain 2

0.356

ARGI1_HUMAN

Arginase-1

0.356

DCPS_HUMAN

m7GpppX diphosphatase

0.356

ASM_HUMAN

Sphingomyelin phosphodiesterase

0.359

DPOG1_HUMAN

DNA polymerase subunit gamma-1

0.360

MTAP_HUMAN

S-methyl-5-thioadenosine phosphorylase

0.361

GORS2_HUMAN

Golgi reassembly-stacking protein 2

0.361

PP2BC_HUMAN

Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform

0.362

LMA2L_HUMAN

VIP36-like protein

0.362

S35F6_HUMAN

Solute carrier family 35 member F6

0.363

COR1B_HUMAN

Coronin-1B

0.364

COR1A_HUMAN

Coronin-1A

0.364

SYNC_HUMAN

Asparagine--tRNA ligase, cytoplasmic

0.365

PP2BB_HUMAN

Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform

0.366

AADAT_HUMAN

Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial

0.366

RABX5_HUMAN

Rab5 GDP/GTP exchange factor

0.366

CLAT_HUMAN

Choline O-acetyltransferase

0.367

COX5A_HUMAN

Cytochrome c oxidase subunit 5A, mitochondrial

0.367

AVL9_HUMAN

Late secretory pathway protein AVL9 homolog

0.367

LMAN2_HUMAN

Vesicular integral-membrane protein VIP36

0.368

RAGP1_HUMAN

Ran GTPase-activating protein 1

0.370

GYS2_HUMAN

Glycogen [starch] synthase, liver

0.370

TMED9_HUMAN

Transmembrane emp24 domain-containing protein 9

0.370

NUCG_HUMAN

Endonuclease G, mitochondrial

0.371

OGFD1_HUMAN

Prolyl 3-hydroxylase OGFOD1

0.371

GYS1_HUMAN

Glycogen [starch] synthase, muscle

0.372

YLAT2_HUMAN

Y+L amino acid transporter 2

0.372

KDM4C_HUMAN

Lysine-specific demethylase 4C

0.372

CTDS1_HUMAN

Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

0.373

STRP2_HUMAN

Striatin-interacting protein 2

0.373

CDK9_HUMAN

Cyclin-dependent kinase 9

0.374

DIC_HUMAN

Mitochondrial dicarboxylate carrier

0.374

RDHE2_HUMAN

Epidermal retinol dehydrogenase 2

0.374

CTDSL_HUMAN

CTD small phosphatase-like protein

0.374

STAM1_HUMAN

Signal transducing adapter molecule 1

0.374

PBDC1_HUMAN

Protein PBDC1

0.374

MIO_HUMAN

GATOR complex protein MIOS

0.375

ATP9A_HUMAN

Probable phospholipid-transporting ATPase IIA

0.375

ZNT1_HUMAN

Zinc transporter 1

0.375

DPP6_HUMAN

Dipeptidyl aminopeptidase-like protein 6

0.376

CAN7_HUMAN

Calpain-7

0.377

C560_HUMAN

Succinate dehydrogenase cytochrome b560 subunit, mitochondrial

0.377

SNX12_HUMAN

Sorting nexin-12

0.378

KDM4A_HUMAN

Lysine-specific demethylase 4A

0.378

TMED4_HUMAN

Transmembrane emp24 domain-containing protein 4

0.379

CPSF4_HUMAN

Cleavage and polyadenylation specificity factor subunit 4

0.379

IDH3G_HUMAN

Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial

0.380

GDE_HUMAN

Glycogen debranching enzyme

0.380

COQ7_HUMAN

5-demethoxyubiquinone hydroxylase, mitochondrial

0.380

FBXW7_HUMAN

F-box/WD repeat-containing protein 7

0.380

AT134_HUMAN

Probable cation-transporting ATPase 13A4

0.381

RDH13_HUMAN

Retinol dehydrogenase 13

0.383

STT3B_HUMAN

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B

0.383

CL065_HUMAN

Probable peptide chain release factor C12orf65, mitochondrial

0.384

NSMA_HUMAN

Sphingomyelin phosphodiesterase 2

0.384

AT2C2_HUMAN

Calcium-transporting ATPase type 2C member 2

0.384

SNX3_HUMAN

Sorting nexin-3

0.385

OXDD_HUMAN

D-aspartate oxidase

0.385

ATP9B_HUMAN

Probable phospholipid-transporting ATPase IIB

0.386

RHOA_HUMAN

Transforming protein RhoA

0.386

CMC2_HUMAN

Calcium-binding mitochondrial carrier protein Aralar2

0.386

DOCK5_HUMAN

Dedicator of cytokinesis protein 5

0.386

TSC2_HUMAN

Tuberin

0.386

UBE3C_HUMAN

Ubiquitin-protein ligase E3C

0.386

GATA4_HUMAN

Transcription factor GATA-4

0.387

HIP1_HUMAN

Huntingtin-interacting protein 1

0.387

MOT12_HUMAN

Monocarboxylate transporter 12

0.388

DOP1_HUMAN

Protein dopey-1

0.388

XPA_HUMAN

DNA repair protein complementing XP-A cells

0.388

TXTP_HUMAN

Tricarboxylate transport protein, mitochondrial

0.388

SRF_HUMAN

Serum response factor

0.389

HGS_HUMAN

Hepatocyte growth factor-regulated tyrosine kinase substrate

0.389

HIP1R_HUMAN

Huntingtin-interacting protein 1-related protein

0.389

PARL_HUMAN

Presenilins-associated rhomboid-like protein, mitochondrial

0.389

PLK1_HUMAN

Serine/threonine-protein kinase PLK1

0.389

MPIP1_HUMAN

M-phase inducer phosphatase 1

0.390

EP15R_HUMAN

Epidermal growth factor receptor substrate 15-like 1

0.390

LBR_HUMAN

Delta(14)-sterol reductase

0.390

WDR59_HUMAN

GATOR complex protein WDR59

0.391

SYRM_HUMAN

Probable arginine--tRNA ligase, mitochondrial

0.391

DOCK3_HUMAN

Dedicator of cytokinesis protein 3

0.391

MK14_HUMAN

Mitogen-activated protein kinase 14

0.392

KDM4B_HUMAN

Lysine-specific demethylase 4B

0.392

HEM1_HUMAN

5-aminolevulinate synthase, nonspecific, mitochondrial

0.392

CBPB1_HUMAN

Carboxypeptidase B

0.392

DYR_HUMAN

Dihydrofolate reductase

0.393

QPCT_HUMAN

Glutaminyl-peptide cyclotransferase

0.394

UB2G2_HUMAN

Ubiquitin-conjugating enzyme E2 G2

0.394

TRM44_HUMAN

Probable tRNA (uracil-O(2)-)-methyltransferase

0.395

YLAT1_HUMAN

Y+L amino acid transporter 1

0.395

CBPA1_HUMAN

Carboxypeptidase A1

0.395

SEC62_HUMAN

Translocation protein SEC62

0.397

MYEF2_HUMAN

Myelin expression factor 2

0.397

DOP2_HUMAN

Protein dopey-2

0.397

DCTN5_HUMAN

Dynactin subunit 5

0.398

AT132_HUMAN

Cation-transporting ATPase 13A2

0.398

SUPT3_HUMAN

Transcription initiation protein SPT3 homolog

0.399

PAXI_HUMAN

Paxillin

0.399

ATPA_HUMAN

ATP synthase subunit alpha, mitochondrial

0.399

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 116 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy