RSLAB_HUMAN 2019

Gene Name RSLAB

Description Ras-like protein family member 10B

Length 203

9606

Sequence

>sp|Q96S79|RSLAB_HUMAN Ras-like protein family member 10B
MVSTYRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDFPPISAFPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSETPIIIVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSVGCARCKHVHAALRFQGALRRNRCAIM

Domains

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What is the source the Gene Ontology annotation?

The Gene Ontology annotations are retrieved from the EBI's QuickGO webservice. Further informations are available in the external data sources section

What is the quality of these annotations?

For now, all GO term annotations, regardless of their evidence code, are displayed. No quality filter are used to provide the widest possible range of annotations. You can check the labels near each annotation for evidence details: manually reviewed annotations are displayed in blue, while the automatic ones are in grey.

Help

What is the source the domain annotation?

The domain annotations are dynamically queried from the Interpro database, using EBI webservice.

The source of these annotations is represented by a color code (see legend). You can access the corresponding Uniprot entries in Interpro by clicking on the synthetic representation of each domain.

Help

What are the distances?

The distances shown here are Jaccard distances, which are adapted to binary profiles (presence/absence).

How are they computed?

Distances between two protein of a given species are computed on phylogenetic profile of each protein in model species of the considered database.

Threshold

The goal of this section is to provide proteins with similar distributions to the query, to that end, we set a maximum threshold at 0.4

Proteins with similar distribution in the three Life domains

Identifier

Description

Distance between phylogenetic profiles

PRD16_HUMAN

Histone-lysine N-methyltransferase PRDM16

0.354

TUTLB_HUMAN

Protein turtle homolog B

0.358

VGLL2_HUMAN

Transcription cofactor vestigial-like protein 2

0.363

PRDM8_HUMAN

PR domain zinc finger protein 8

0.368

SCHI1_HUMAN

Schwannomin-interacting protein 1

0.387

CTCF_HUMAN

Transcriptional repressor CTCF

0.387

PA2G3_HUMAN

Group 3 secretory phospholipase A2

0.392

CHRD_HUMAN

Chordin

0.392

RFX7_HUMAN

DNA-binding protein RFX7

0.392

IQIP1_HUMAN

IQCJ-SCHIP1 readthrough transcript protein

0.392

TWSG1_HUMAN

Twisted gastrulation protein homolog 1

0.392

ZEP2_HUMAN

Transcription factor HIVEP2

0.392

ZEP1_HUMAN

Zinc finger protein 40

0.392

GBX2_HUMAN

Homeobox protein GBX-2

0.397

ZN423_HUMAN

Zinc finger protein 423

0.397

GRPR_HUMAN

Gastrin-releasing peptide receptor

0.397

Proteins with similar distribution in Eukaryota

Identifier

Description

Distance between phylogenetic profiles

ETV6_HUMAN

Transcription factor ETV6

0.327

CTCF_HUMAN

Transcriptional repressor CTCF

0.332

PA2G3_HUMAN

Group 3 secretory phospholipase A2

0.344

CUED2_HUMAN

CUE domain-containing protein 2

0.344

VGLL2_HUMAN

Transcription cofactor vestigial-like protein 2

0.347

T183A_HUMAN

Transmembrane protein 183A

0.347

CHSTB_HUMAN

Carbohydrate sulfotransferase 11

0.356

DSCL1_HUMAN

Down syndrome cell adhesion molecule-like protein 1

0.356

GPM6A_HUMAN

Neuronal membrane glycoprotein M6-a

0.356

DLP1_HUMAN

Decaprenyl-diphosphate synthase subunit 2

0.361

TCF21_HUMAN

Transcription factor 21

0.366

NINJ1_HUMAN

Ninjurin-1

0.369

TWSG1_HUMAN

Twisted gastrulation protein homolog 1

0.369

NRF1_HUMAN

Nuclear respiratory factor 1

0.369

DFFB_HUMAN

DNA fragmentation factor subunit beta

0.371

MED30_HUMAN

Mediator of RNA polymerase II transcription subunit 30

0.372

INTU_HUMAN

Protein inturned

0.373

CCD43_HUMAN

Coiled-coil domain-containing protein 43

0.376

SYT14_HUMAN

Synaptotagmin-14

0.379

NKRF_HUMAN

NF-kappa-B-repressing factor

0.379

SP130_HUMAN

Histone deacetylase complex subunit SAP130

0.381

TNR6C_HUMAN

Trinucleotide repeat-containing gene 6C protein

0.383

GABPA_HUMAN

GA-binding protein alpha chain

0.383

T179A_HUMAN

Transmembrane protein 179

0.384

GRPR_HUMAN

Gastrin-releasing peptide receptor

0.384

IKKA_HUMAN

Inhibitor of nuclear factor kappa-B kinase subunit alpha

0.384

NKD1_HUMAN

Protein naked cuticle homolog 1

0.384

UBP1_HUMAN

Ubiquitin carboxyl-terminal hydrolase 1

0.385

DCA10_HUMAN

DDB1- and CUL4-associated factor 10

0.386

ZMYM4_HUMAN

Zinc finger MYM-type protein 4

0.387

CHRD_HUMAN

Chordin

0.389

TM35A_HUMAN

Transmembrane protein 35A

0.389

IKKB_HUMAN

Inhibitor of nuclear factor kappa-B kinase subunit beta

0.390

ID2_HUMAN

DNA-binding protein inhibitor ID-2

0.390

USH1C_HUMAN

Harmonin

0.390

SPRE2_HUMAN

Sprouty-related, EVH1 domain-containing protein 2

0.391

MBD5_HUMAN

Methyl-CpG-binding domain protein 5

0.392

RREB1_HUMAN

Ras-responsive element-binding protein 1

0.392

PQLC3_HUMAN

PQ-loop repeat-containing protein 3

0.392

GCM2_HUMAN

Chorion-specific transcription factor GCMb

0.393

USH1G_HUMAN

Usher syndrome type-1G protein

0.393

SASH3_HUMAN

SAM and SH3 domain-containing protein 3

0.393

PRDM8_HUMAN

PR domain zinc finger protein 8

0.394

KIBRA_HUMAN

Protein KIBRA

0.395

CRBL2_HUMAN

cAMP-responsive element-binding protein-like 2

0.395

CASZ1_HUMAN

Zinc finger protein castor homolog 1

0.395

PHC2_HUMAN

Polyhomeotic-like protein 2

0.395

CRHBP_HUMAN

Corticotropin-releasing factor-binding protein

0.395

ZMYM2_HUMAN

Zinc finger MYM-type protein 2

0.396

KAZRN_HUMAN

Kazrin

0.397

OAF_HUMAN

Out at first protein homolog

0.397

TDRKH_HUMAN

Tudor and KH domain-containing protein

0.397

LYSC_HUMAN

Lysozyme C

0.398

ZN423_HUMAN

Zinc finger protein 423

0.398

ENOX1_HUMAN

Ecto-NOX disulfide-thiol exchanger 1

0.398

REL_HUMAN

Proto-oncogene c-Rel

0.398

CDR2_HUMAN

Cerebellar degeneration-related protein 2

0.398

ZCHC2_HUMAN

Zinc finger CCHC domain-containing protein 2

0.398

SAPC2_HUMAN

Suppressor APC domain-containing protein 2

0.398

K0825_HUMAN

Uncharacterized protein KIAA0825

0.399

NMBR_HUMAN

Neuromedin-B receptor

0.399

MED28_HUMAN

Mediator of RNA polymerase II transcription subunit 28

0.400

KANL1_HUMAN

KAT8 regulatory NSL complex subunit 1

0.400

Orthologs and taxonomic distribution

Eukaryota: Model Organisms
Eukaryota: Whole domain
Three domains

Orthologs found in 35 organisms (of 162)

Taxonomic distribution summary

Help

This section gives an overview of the taxonomic distribution of orthologs in representative clades. Clade names correspond to NCBI taxonomy or to the accepted consensus. Classification of each species into clade is available here

Legend:

Heatmap

Each labelled tile corresponds to a clade and is colored according to the proportion of species in the clade with at least one ortholog using the following scale:

25%

50%

75%

100%

Hover on the heatmap to see the total number of species in which orthologs were found.

Tiles framed in blue indicate the clade for which a 'focused' view is available, you can click the tile to reveal it

Labels

Label colors correspond to one of three domains of Life

Eukaryota

Archaea

Bacteria

Inparalogs

When inparalogs (genes in query species resulting from a duplication event posterior to the speciation with target species) are detected, they can be displayed under the 'See Inparalogs' button. A indicates that this protein is a predicted inparalog to the query protein, relatively to (at least) one species of this clade.

Not found in

The 'Not found in' button offers the list of species in which orthologs where not found, ordered clade by clade

See inparalogs

Orthologs not found in

	Relationship type	Query & inparalogs	Orthologs	Orthologs length	Species	Taxid		Taxonomy	Whole Taxonomy